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1.发明申请公开(公告)号：US20030045603A1
公开(公告)日：2003-03-06
申请号：US10262869
申请日：2002-10-03
发明人： Ronald Salovey , Harry A. McKellop , Fu-Wen Shen
IPC分类号： A61F002/00 , C08F210/00
CPC分类号： A61F2/30 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/468 , A61F2002/30233 , A61F2002/3082 , A61F2002/30879 , A61F2002/3611 , A61F2230/0069 , A61L27/16 , B29B13/08 , B29C43/00 , B29C43/16 , B29C71/0063 , B29C2035/085 , B29K2023/0683 , B29K2105/24 , B29K2995/0087 , B29K2995/0089 , B29L2031/7532 , C08J5/00 , C08J7/047 , C08J2323/06 , C08L23/06
摘要： The present invention discloses a method for enhancing the wear-resistance of polymers by crosslinking them, especially before irradiation sterilization. In particular, this invention presents the use of chemically crosslinked ultrahigh molecular weight polyethylene in in vivo implants.
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2.发明申请Crosslinking of polyethylene for low wear using radiation and thermal treatments 有权使用辐射和热处理交联聚乙烯低磨损公开(公告)号：US20020037944A1
公开(公告)日：2002-03-28
申请号：US09795229
申请日：2001-02-26
发明人： Fu-Wen Shen , Harry A. McKellop , Ronald Salovey
IPC分类号： C08J003/28
CPC分类号： A61F2/30767 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/468 , A61F2002/30084 , A61F2002/3414 , A61F2002/3429 , A61F2002/3611 , A61L27/16 , B29C43/00 , B29C43/16 , B29C71/02 , B29C71/04 , B29C2035/085 , B29C2071/022 , B29K2023/0675 , B29K2023/0683 , B29K2995/0087 , B29K2995/0089 , B29L2031/7532 , C08J3/28 , C08J7/08 , C08J7/123 , C08J2323/06 , Y10S525/937 , C08L23/06
摘要： The present invention discloses methods for enhancing the wear-resistance of polymers, the resulting polymers, and in vivo implants made from such polymers. One aspect of this invention presents a method whereby a polymer is irradiated, preferably with gamma radiation, then thermally treated, such as by remelting of annealing. The resulting polymeric composition preferably has its most oxidized surface layer removed. Another aspect of the invention presents a general method for optimizing the wear resistance and desirable physical and/or chemical properties of a polymer by crosslinking and thermally treating it. The resulting polymeric compositions is wear-resistant and may be fabricated into an in vivo implant.
摘要翻译： 本发明公开了提高聚合物，所得聚合物和由这些聚合物制成的体内植入物的耐磨性的方法。 本发明的一个方面提出了一种方法，其中聚合物优选用γ辐射照射，然后进行热处理，例如通过重熔退火。 所得的聚合物组合物优选地除去其最被氧化的表面层。 本发明的另一方面提出了通过交联和热处理来优化聚合物的耐磨性和所需物理和/或化学性质的一般方法。 所得的聚合物组合物是耐磨的并且可以制成体内植入物。
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3.发明申请Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints 审中-公开化学交联超高分子量聚乙烯人造人体接头公开(公告)号：US20010049401A1
公开(公告)日：2001-12-06
申请号：US09898192
申请日：2001-07-02
发明人： Ronald Salovey , Harry A. McKellop , Fu-Wen Shen
IPC分类号： A61F002/00
CPC分类号： A61F2/30 , A61F2/3094 , A61F2/32 , A61F2/34 , A61F2/468 , A61F2002/30233 , A61F2002/3082 , A61F2002/30879 , A61F2002/3611 , A61F2230/0069 , A61L27/16 , B29B13/08 , B29C43/00 , B29C43/16 , B29C71/0063 , B29C2035/085 , B29K2023/0683 , B29K2105/24 , B29K2995/0087 , B29K2995/0089 , B29L2031/7532 , C08J5/00 , C08J7/047 , C08J2323/06 , C08L23/06
摘要： The present invention discloses a method for enhancing the wear-resistance of polymers by crosslinking them, especially before irradiation sterilization. In particular, this invention presents the use of chemically crosslinked ultrahigh molecular weight polyethylene in in vivo implants.
摘要翻译： 本发明公开了一种提高聚合物的耐磨性的方法，特别是在照射灭菌之前。 特别地，本发明提供了在体内植入物中使用化学交联的超高分子量聚乙烯。
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公开(公告)号：US09242025B2
公开(公告)日：2016-01-26
申请号：US14489069
申请日：2014-09-17
申请人： ORTHOPAEDIC HOSPITAL
发明人： Harry A. McKellop , Fu-Wen Shen
IPC分类号： C08J3/28 , A61F2/32 , A61L27/16 , A61L2/08 , A61L27/50 , B65B55/16 , B29C35/08 , B29C43/00 , B29C47/00 , A61F2/30 , A61F2/34 , A61F2/38 , B29K23/00
CPC分类号： A61L27/16 , A61F2/3094 , A61F2/34 , A61F2/38 , A61L2/081 , A61L27/50 , A61L2430/24 , B29C35/0805 , B29C35/0866 , B29C43/003 , B29C47/0004 , B29C2035/085 , B29C2035/0877 , B29K2023/0683 , B65B55/16 , C08J3/28 , C08J2323/06 , C08L23/06
摘要： The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.
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公开(公告)号：US20150096264A1
公开(公告)日：2015-04-09
申请号：US14566084
申请日：2014-12-10
发明人： Harry A. McKellop , Fu-Wen Shen
CPC分类号： A61L27/16 , A61F2/3094 , A61F2/34 , A61F2/38 , A61L2/081 , A61L27/50 , A61L2430/24 , B29C35/0805 , B29C35/0866 , B29C43/003 , B29C47/0004 , B29C2035/085 , B29C2035/0877 , B29K2023/0683 , B65B55/16 , C08J3/28 , C08J2323/06 , C08L23/06
摘要： The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.
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6.发明申请公开(公告)号：US20140235745A1
公开(公告)日：2014-08-21
申请号：US14262553
申请日：2014-04-25
发明人： Harry A. McKellop , Fu-Wen Shen
CPC分类号： A61L27/16 , A61F2/3094 , A61F2/34 , A61F2/38 , A61L2/081 , A61L27/50 , A61L2430/24 , B29C35/0805 , B29C35/0866 , B29C43/003 , B29C47/0004 , B29C2035/085 , B29C2035/0877 , B29K2023/0683 , B65B55/16 , C08J3/28 , C08J2323/06 , C08L23/06
摘要： The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.
摘要翻译： 本发明提出了制造耐氧化和耐磨聚乙烯的方法和由其制成的医疗植入物。 优选地，植入物是假肢关节的部件，例如人造髋关节或膝关节的支承部件。 还公开了所得的抗氧化和耐磨聚乙烯和植入物。
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公开(公告)号：US09302028B2
公开(公告)日：2016-04-05
申请号：US14262553
申请日：2014-04-25
申请人： ORTHOPAEDIC HOSPITAL
发明人： Harry A. McKellop , Fu-Wen Shen
IPC分类号： C08G73/06 , A61L27/16 , A61L2/08 , A61L27/50 , C08J3/28 , B65B55/16 , B29C35/08 , B29C43/00 , B29C47/00 , A61F2/30 , A61F2/34 , A61F2/38 , B29K23/00
CPC分类号： A61L27/16 , A61F2/3094 , A61F2/34 , A61F2/38 , A61L2/081 , A61L27/50 , A61L2430/24 , B29C35/0805 , B29C35/0866 , B29C43/003 , B29C47/0004 , B29C2035/085 , B29C2035/0877 , B29K2023/0683 , B65B55/16 , C08J3/28 , C08J2323/06 , C08L23/06
摘要： The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.
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公开(公告)号：US09155817B2
公开(公告)日：2015-10-13
申请号：US14566084
申请日：2014-12-10
申请人： ORTHOPAEDIC HOSPITAL
发明人： Harry A. McKellop , Fu-Wen Shen
IPC分类号： C08J3/28 , A61F2/32 , A61L27/16 , A61L2/08 , A61L27/50 , B65B55/16 , B29C35/08 , B29C43/00 , B29C47/00 , A61F2/30 , A61F2/34 , A61F2/38 , B29K23/00
CPC分类号： A61L27/16 , A61F2/3094 , A61F2/34 , A61F2/38 , A61L2/081 , A61L27/50 , A61L2430/24 , B29C35/0805 , B29C35/0866 , B29C43/003 , B29C47/0004 , B29C2035/085 , B29C2035/0877 , B29K2023/0683 , B65B55/16 , C08J3/28 , C08J2323/06 , C08L23/06
摘要： The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.
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9.发明申请公开(公告)号：US20150007527A1
公开(公告)日：2015-01-08
申请号：US14489069
申请日：2014-09-17
发明人： Harry A. McKellop , Fu-Wen Shen
CPC分类号： A61L27/16 , A61F2/3094 , A61F2/34 , A61F2/38 , A61L2/081 , A61L27/50 , A61L2430/24 , B29C35/0805 , B29C35/0866 , B29C43/003 , B29C47/0004 , B29C2035/085 , B29C2035/0877 , B29K2023/0683 , B65B55/16 , C08J3/28 , C08J2323/06 , C08L23/06
摘要： The present invention presents methods for making oxidation-resistant and wear-resistant polyethylenes and medical implants made therefrom. Preferably, the implants are components of prosthetic joints, e.g., a bearing component of an artificial hip or knee joint. The resulting oxidation-resistant and wear-resistant polyethylenes and implants are also disclosed.
摘要翻译： 本发明提出了制造耐氧化和耐磨聚乙烯的方法和由其制成的医疗植入物。 优选地，植入物是假肢关节的部件，例如人造髋关节或膝关节的支承部件。 还公开了所得的抗氧化和耐磨聚乙烯和植入物。
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