FULLY INTEGRATED COMPLEMENTARY METAL OXIDE SEMICONDUCTOR (CMOS) FOURIER TRANSFORM INFRARED (FTIR) SPECTROMETER AND RAMAN SPECTROMETER
    1.
    发明申请
    FULLY INTEGRATED COMPLEMENTARY METAL OXIDE SEMICONDUCTOR (CMOS) FOURIER TRANSFORM INFRARED (FTIR) SPECTROMETER AND RAMAN SPECTROMETER 审中-公开
    完全集成的补充金属氧化物半导体(CMOS)FOURIER变换红外(FTIR)光谱仪和拉曼光谱仪

    公开(公告)号:US20130321816A1

    公开(公告)日:2013-12-05

    申请号:US13985550

    申请日:2012-02-14

    IPC分类号: G01J3/45

    摘要: A Fourier Transform Infrared (FTIR) Spectrometer integrated in a CMOS technology on a Silicon-on-Insulator (SOI) wafer is disclosed. The present invention is fully integrated into a compact, miniaturized, low cost, CMOS fabrication compatible chip. The present invention may be operated in various infrared regions ranging from 1.1 μm to 15 μm or it can cover the full spectrum from 1.1 μm to 15 μm all at once.The CMOS-FTIR spectrometer disclosed herein has high spectral resolution, no movable parts, no lenses, is compact, not prone to damage in harsh external conditions and can be fabricated with a standard CMOS technology, allowing the mass production of FTIR spectrometers. The fully integrated CMOS-FTIR spectrometer is suitable for battery operation; any and all functionality can be integrated on a chip with standard CMOS technology. The disclosed invention for the FTIR spectrometer may also be adapted for a CMOS-Raman spectrometer.

    摘要翻译: 公开了在绝缘体上硅(SOI)晶片上集成在CMOS技术中的傅里叶变换红外(FTIR)光谱仪。 本发明完全集成到紧凑型,小型化,低成本的CMOS制造兼容芯片中。 本发明可以在从1.1μm到15μm的各种红外区域中操作,或者它可以一次覆盖1.1μm至15μm的全光谱。 本文公开的CMOS-FTIR光谱仪具有高光谱分辨率,无可移动部件,无透镜,紧凑,在恶劣的外部条件下不容易损坏,并且可以使用标准CMOS技术制造,允许大量生产FTIR光谱仪。 完全集成的CMOS-FTIR光谱仪适用于电池操作; 任何和所有功能可以集成在具有标准CMOS技术的芯片上。 所公开的FTIR光谱仪的发明也可以适用于CMOS-拉曼光谱仪。

    INGESTIBLE IMPLEMENT FOR WEIGHT CONTROL
    2.
    发明申请
    INGESTIBLE IMPLEMENT FOR WEIGHT CONTROL 有权
    不可控制的重量控制

    公开(公告)号:US20100215732A1

    公开(公告)日:2010-08-26

    申请号:US12294659

    申请日:2007-03-29

    摘要: An orally administrable implement for expanding in a stomach of an animal, including a mammal, to fill a space in the stomach, is provided for weight control. The implement includes: a fluid-permeable expandable container having a first dimension and a second dimension; and a plurality of clusters comprising a swellable material contained within the container and capable of swelling when contacted with a fluid; whereby when the implement is ingested, the fluid in the stomach enters the container causing the clusters therein to swell and the container to expand from the first dimension to the second dimension.

    摘要翻译: 提供用于在包括哺乳动物的动物的胃中扩张以填充胃中的空间的可口服施用的装置,用于重量控制。 所述工具包括:具有第一尺寸和第二尺寸的流体可渗透的可膨胀容器; 以及包括容纳在容器内并且当与流体接触时能够膨胀的可溶胀材料的多个簇; 从而当器具被摄取时,胃中的流体进入容器,导致其中的簇膨胀并且容器从第一尺寸膨胀到第二尺寸。

    Cytometer
    3.
    发明申请
    Cytometer 审中-公开
    细胞计数器

    公开(公告)号:US20070086918A1

    公开(公告)日:2007-04-19

    申请号:US11278173

    申请日:2006-03-31

    IPC分类号: G01N33/00

    CPC分类号: G01N15/1484 G01N15/1459

    摘要: A real-time digital cytometer on a chip system utilizing a custom near field CMOS active pixel intelligent sensor that is flip-chip attached to a fluidic microchannel etched in a thin glass substrate. The CMOS active pixel sensor, fabricated using a 0.18 micron process, is a mixed signal chip comprising a sixteen pixel linear adaptive spatial filter coupled to a digital serial interface. This near field hybrid digital sensor topology obviates the need for both high resolution analog to digital conversion as well as conventional microscopy for the realization of real time optical cytometry. The custom sensor based design approach affords efficient scaling into a tiled multi-channel sensing configuration. The complete system, supported by a handheld graphical user interface and control module, demonstrates a viable micro total analysis sub-system for sample preparation and analysis which can support a wide range of applications ranging from cytometry to cell growth kinetics and analysis and various forms of fluid and droplet metering on an integrated and compact microfluidic platform.

    摘要翻译: 一种利用定制的近场CMOS有源像素智能传感器的芯片系统上的实时数字细胞仪,其被倒装连接到在薄玻璃基板上蚀刻的流体微通道。 使用0.18微米工艺制造的CMOS有源像素传感器是包括耦合到数字串行接口的十六像素线性自适应空间滤波器的混合信号芯片。 这种近场混合数字传感器拓扑结构不需要高分辨率模数转换以及常规显微镜来实现实时光学细胞计数。 基于定制传感器的设计方法提供了有效的扩展到平铺多通道感测配置。 完整的系统由手持式图形用户界面和控制模块支持,展示了可用于样品制备和分析的可行的微型总分析子系统,可以支持从细胞计数到细胞生长动力学和分析的各种应用,以及各种形式的 流体和液滴计量在集成和紧凑的微流体平台上。

    Image sensor with high dynamic range linear output
    4.
    发明授权
    Image sensor with high dynamic range linear output 有权
    具有高动态范围线性输出的图像传感器

    公开(公告)号:US07190398B1

    公开(公告)日:2007-03-13

    申请号:US09654922

    申请日:2000-09-05

    IPC分类号: H04N3/14 G03B7/00

    摘要: Designs and operational methods to increase the dynamic range of image sensors and APS devices in particular by achieving more than one integration times for each pixel thereof. An APS system with more than one column-parallel signal chains for readout are described for maintaining a high frame rate in readout. Each active pixel is sampled for multiple times during a single frame readout, thus resulting in multiple integration times. The operation methods can also be used to obtain multiple integration times for each pixel with an APS design having a single column-parallel signal chain for readout. Furthermore, analog-to-digital conversion of high speed and high resolution can be implemented.

    摘要翻译: 特别是通过为其每个像素实现一个以上的积分时间来增加图像传感器和APS装置的动态范围的设计和操作方法。 描述了具有用于读出的多个列并行信号链的APS系统,用于在读出中维持高帧速率。 在单帧读出期间,每个有源像素被采样多次,从而导致多次积分时间。 操作方法也可以用于通过具有单列并行信号链的APS设计为每个像素获得多个积分时间用于读出。 此外,可以实现高速和高分辨率的模数转换。

    Center of mass detection via an active pixel sensor
    6.
    发明授权
    Center of mass detection via an active pixel sensor 失效
    通过有源像素传感器进行质量检测中心

    公开(公告)号:US06476860B1

    公开(公告)日:2002-11-05

    申请号:US09114347

    申请日:1998-07-13

    IPC分类号: H04N5225

    摘要: An imaging system for identifying the location of the center of mass (“COM”) in an image. In one aspect, an imaging system includes a plurality of photosensitive elements arranged in a matrix. A center of mass circuit coupled to the photosensitive elements includes a resistive network and a normalization circuit including at least one bipolar transistor. The center of mass circuit identifies a center of mass location in the matrix and includes: a row circuit, where the row circuit identifies a center of mass row value in each row of the matrix and identifies a row intensity for each row; a horizontal circuit, where the horizontal circuit identifies a center of mass horizontal value; and a vertical circuit, where the vertical circuit identifies a center of mass vertical value. The horizontal and vertical center of mass values indicate the coordinates of the center of mass location for the image.

    摘要翻译: 用于识别图像中的质心(“COM”)的位置的成像系统。 在一个方面,成像系统包括以矩阵形式布置的多个感光元件。 耦合到感光元件的质量电路的中心包括电阻网络和包括至少一个双极晶体管的归一化电路。 质心电路识别矩阵中的质心位置,包括:行电路,其中行电路识别矩阵的每行中的质心行值,并识别每行的行强度; 水平电路,其中水平电路识别质心水平值; 和垂直电路,其中垂直电路标识质心垂直值。 水平和垂直质心值表示图像的质心位置的坐标。

    Ingestible implement for weight control
    8.
    发明授权
    Ingestible implement for weight control 有权
    用于体重控制的可食用器具

    公开(公告)号:US09579227B2

    公开(公告)日:2017-02-28

    申请号:US13687153

    申请日:2012-11-28

    IPC分类号: A61M29/00 A61F5/00

    CPC分类号: A61F5/0073

    摘要: An orally administrable implement for expanding in a stomach of an animal, including a mammal, to fill a space in the stomach, is provided for weight control. The implement includes: a fluid-permeable expandable container having a first dimension and a second dimension; and a plurality of clusters comprising a swellable material contained within the container and capable of swelling when contacted with a fluid; whereby when the implement is ingested, the fluid in the stomach enters the container causing the clusters therein to swell and the container to expand from the first dimension to the second dimension.

    摘要翻译: 提供用于在包括哺乳动物的动物的胃中扩张以填充胃中的空间的可口服施用的装置,用于重量控制。 所述工具包括:具有第一尺寸和第二尺寸的流体可渗透的可膨胀容器; 以及包括容纳在容器内并且当与流体接触时能够膨胀的可溶胀材料的多个簇; 从而当器具被摄取时,胃中的流体进入容器,导致其中的簇膨胀并且容器从第一尺寸膨胀到第二尺寸。

    Ingestible implement for weight control
    10.
    发明授权
    Ingestible implement for weight control 有权
    用于体重控制的可食用器具

    公开(公告)号:US08389003B2

    公开(公告)日:2013-03-05

    申请号:US12294659

    申请日:2007-03-29

    摘要: An orally administrable implement for expanding in a stomach of an animal, including a mammal, to fill a space in the stomach, is provided for weight control. The implement includes: a fluid-permeable expandable container having a first dimension and a second dimension; and a plurality of clusters comprising a swellable material contained within the container and capable of swelling when contacted with a fluid; whereby when the implement is ingested, the fluid in the stomach enters the container causing the clusters therein to swell and the container to expand from the first dimension to the second dimension.

    摘要翻译: 提供用于在包括哺乳动物的动物的胃中扩张以填充胃中的空间的可口服施用的装置,用于重量控制。 所述工具包括:具有第一尺寸和第二尺寸的流体可渗透的可膨胀容器; 以及包括容纳在容器内并且当与流体接触时能够膨胀的可溶胀材料的多个簇; 从而当器具被摄取时,胃中的流体进入容器,导致其中的簇膨胀并且容器从第一尺寸膨胀到第二尺寸。