Abstract:
The present invention relates to a collapsible pocket-sized ball toy and a pocket-sized container or package for the toy, wherein the toy comprises a light weight exterior covering surrounding a light weight expandable spring.
Abstract:
Compounds of the formula I are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy, particular in the management of pain, and more particularly in the management of pain during labor.
Abstract:
An impermeable cooled closing plug adapted for closing the end of a semiconductor manufacture processing tube is made of a material selected from the group consisting of quartz, silicon and silicon carbide, which materials have low heat conductivity and high chemical stability. The cooling effects of a cooling liquid supplied to the entrance flange of a processing tube are isolated from the tube closing plug by virtue of the low heat conductivity, thus preventing unwanted condensation effects at the entrance of the tube.
Abstract:
Compositions comprising an antioxidant directed or indirectly conjugated to an aromatic-cationic peptide are provide. Said antioxidants are selected from TEMPO, Tro, PBN, AHDP, DBHP, Caf and Hem and may be conjugated to the aromatic-cationic peptide directly or indirectly via a linker to the N-terminus, C-terminus or a side chain of an amino acid residue of the aromatic-cationic peptide. In some embodiments, the aromatic-cationic peptide is 2′,6′-Dmt-D-Arg-Phe-Lys-NH2, Phe-D-Arg-Phe-Lys-NH2 or D-Arg-2′,6′-Dmt-Lys-Phe-NH2. These conjugates have increased antioxidant activity as compared to the unconjugated aromatic-cationic peptide and have utility in treating complex regional pain syndrome.
Abstract:
The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2 a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1.
Abstract:
The present invention provides methods for stimulating mu-opioid receptors with agonist peptides in a mammal in need thereof. The methods comprise administering to the mammal an effective amount of a selective mu-opioid receptor agonist peptide that comprises at least two α-amino acid residues. At least one of the amino acid residues has a positive charge. The amino acid residue in the first position is a tyrosine or tyrosine derivative. The amino acid in the second position is a D-α-amino acid. The present invention also provides methods of treating a mammal suffering from conditions or diseases by administering to the mammal an effective amount of the peptides.
Abstract:
The present invention provides a solid-state rotational rate sensor device formed by a thin-film for generating an electrical voltage output proportional to the rate of rotational motion. The precision thin-film piezoelectric elements are configured and arranged on a semi-rigid structure to detect rotation (such as pitch, roll, and yaw) while rejecting spurious noise created by vibration, thermal gradients, and electromagnetic interference.
Abstract:
A valve arrangement of a loom includes valve modules held between flange plates and sharing a common inlet feeding into a common inner valve space. A valve outlet of each valve module leads to an insertion nozzle or nozzle group, and is controlled by a valve disk actuated by a piezoelectric actuator to rapidly dynamically adjust the pressure profile. A quality parameter, characteristic of the thread insertion flight time of each weft thread, is stored in a data bank and has a nominal pressure profile for achieving a nominal thread flight time allocated thereto. The actual thread flight time of each weft thread is measured and compared with the stored nominal thread flight time. A control signal responsive to the time difference is provided to the valve arrangement to control the piezoelectric actuator so as to adjust the pressure and/or the quantity of the pressure medium provided through the valve module to the connected insertion nozzle. Alternatively, the control signal is provided to the main loom rotational drive to adjust the rotational speed of the loom.
Abstract:
A method and apparatus employs Hall probes for contactless, longitudinal and transversal homogeneity examination of a critical current density j.sub.c in a superconductor tape that is cooled to below a transition temperature T.sub.c. The cooled superconductor tape is pulled through an external, locally limited magnetic field that has a constant gradient and a fixed magnetic field axis. The magnetic field generated by a screening current induced in a region of the superconductor tape penetrated by the external magnetic field is scanned using a first Hall probe at a distance of a few tenths of millimeters to the superconductor tape. The external magnetic field outside of a field range of the induced persistent currents is measured with a second Hall probe. A compensated difference between the first and second Hall probe signals is used as a qualitative measure for a critical current density j.sub.c (x) and its longitudinal homogeneity which varies locally with respect to a longitudinal axis of the superconductor tape. The compensated difference is formed by adjusting a test difference between the two Hall probe signals to zero as a result of measuring the external magnetic field by both Hall probes in a dummy measurement conducted without the superconductor tape. A transverse homogeneity with a linear Hall probe array that is positioned crosswise to the longitudinal axis of the superconductor tape and extends broadside over the superconductor tape is measured after all Hall probes in the array have first been adjusted to zero with a signal from the second probe. Quantitative locally critical current densities are specified from the Hall probe signals by a resistive calibration obtained from a current-voltage measurement.