POCKET BALL TOY
    1.
    发明申请
    POCKET BALL TOY 审中-公开
    POCKET BALL玩具

    公开(公告)号:US20140349791A1

    公开(公告)日:2014-11-27

    申请号:US14284323

    申请日:2014-05-21

    Applicant: Peter Schiller

    Inventor: Peter Schiller

    CPC classification number: A63B39/00 A63B2039/003 A63B2210/54

    Abstract: The present invention relates to a collapsible pocket-sized ball toy and a pocket-sized container or package for the toy, wherein the toy comprises a light weight exterior covering surrounding a light weight expandable spring.

    Abstract translation: 本发明涉及一种可折叠的口袋尺寸的球形玩具和用于玩具的袖珍尺寸的容器或包装,其中该玩具包括围绕重量轻的可膨胀弹簧的重量轻的外部覆盖物。

    Compounds useful in pain management
    2.
    发明授权
    Compounds useful in pain management 有权
    化合物可用于疼痛管理

    公开(公告)号:US06703483B1

    公开(公告)日:2004-03-09

    申请号:US09590165

    申请日:2000-06-09

    Applicant: Peter Schiller

    Inventor: Peter Schiller

    CPC classification number: C07K5/1016 A61K38/00 A61K38/07

    Abstract: Compounds of the formula I are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy, particular in the management of pain, and more particularly in the management of pain during labor.

    Abstract translation: 本申请中公开和要求保护的式I化合物及其药学上可接受的盐,包含新化合物的药物组合物及其在治疗中的用途,特别是在治疗疼痛方面的用途,尤其是在劳动中的疼痛管理中 。

    AROMATIC-CATIONIC PEPTIDES CONJUGATED TO ANTIOXIDANTS AND THEIR USE IN TREATING COMPLEX REGIONAL PAIN SYNDROME

    公开(公告)号:US20200308220A1

    公开(公告)日:2020-10-01

    申请号:US15779593

    申请日:2016-11-29

    Abstract: Compositions comprising an antioxidant directed or indirectly conjugated to an aromatic-cationic peptide are provide. Said antioxidants are selected from TEMPO, Tro, PBN, AHDP, DBHP, Caf and Hem and may be conjugated to the aromatic-cationic peptide directly or indirectly via a linker to the N-terminus, C-terminus or a side chain of an amino acid residue of the aromatic-cationic peptide. In some embodiments, the aromatic-cationic peptide is 2′,6′-Dmt-D-Arg-Phe-Lys-NH2, Phe-D-Arg-Phe-Lys-NH2 or D-Arg-2′,6′-Dmt-Lys-Phe-NH2. These conjugates have increased antioxidant activity as compared to the unconjugated aromatic-cationic peptide and have utility in treating complex regional pain syndrome.

    METHODS FOR PREVENTING MITOCHONDRIAL PERMEABILITY TRANSITION
    6.
    发明申请
    METHODS FOR PREVENTING MITOCHONDRIAL PERMEABILITY TRANSITION 有权
    防止麻醉渗透性过渡的方法

    公开(公告)号:US20070027087A1

    公开(公告)日:2007-02-01

    申请号:US11427804

    申请日:2006-06-30

    Abstract: The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2 a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1.

    Abstract translation: 本发明提供了减少或预防线粒体渗透性转换的方法。 该方法包括施用有效量的具有至少一个净正电荷的芳族阳离子肽; 至少四个氨基酸; 最多约20个氨基酸; 净正电荷的最小数量(p t)之间的关系,其中2 a是小于或等于p < t + 1,除了当a为1时,p 也可以为1。

    Medicinal Uses of Mu-Opioid Receptor Agonists
    7.
    发明申请
    Medicinal Uses of Mu-Opioid Receptor Agonists 有权
    Mu-Opioid受体激动剂的药物用途

    公开(公告)号:US20070027070A1

    公开(公告)日:2007-02-01

    申请号:US11427606

    申请日:2006-06-29

    CPC classification number: A61K38/12 A61K38/07 A61K38/08

    Abstract: The present invention provides methods for stimulating mu-opioid receptors with agonist peptides in a mammal in need thereof. The methods comprise administering to the mammal an effective amount of a selective mu-opioid receptor agonist peptide that comprises at least two α-amino acid residues. At least one of the amino acid residues has a positive charge. The amino acid residue in the first position is a tyrosine or tyrosine derivative. The amino acid in the second position is a D-α-amino acid. The present invention also provides methods of treating a mammal suffering from conditions or diseases by administering to the mammal an effective amount of the peptides.

    Abstract translation: 本发明提供了在有需要的哺乳动物中用激动剂肽刺激μ-阿片受体的方法。 所述方法包括向哺乳动物施用有效量的包含至少两个α-氨基酸残基的选择性μ-阿片受体激动剂肽。 至少一个氨基酸残基具有正电荷。 第一位置的氨基酸残基是酪氨酸或酪氨酸衍生物。 第二个位置的氨基酸是D-α-氨基酸。 本发明还提供了通过向哺乳动物施用有效量的肽来治疗患有病症或疾病的哺乳动物的方法。

    Solid-state rotational rate sensor device and method
    8.
    发明申请
    Solid-state rotational rate sensor device and method 审中-公开
    固态转速传感器装置及方法

    公开(公告)号:US20060032307A1

    公开(公告)日:2006-02-16

    申请号:US11202937

    申请日:2005-08-12

    Applicant: Peter Schiller

    Inventor: Peter Schiller

    CPC classification number: G01C19/56

    Abstract: The present invention provides a solid-state rotational rate sensor device formed by a thin-film for generating an electrical voltage output proportional to the rate of rotational motion. The precision thin-film piezoelectric elements are configured and arranged on a semi-rigid structure to detect rotation (such as pitch, roll, and yaw) while rejecting spurious noise created by vibration, thermal gradients, and electromagnetic interference.

    Abstract translation: 本发明提供一种由薄膜形成的固态转速传感器装置,用于产生与旋转运动速率成比例的电压输出。 精密薄膜压电元件被配置和布置在半刚性结构上以检测旋转(例如俯仰,滚转和偏转),同时抑制由振动,热梯度和电磁干扰产生的杂散噪声。

    Jet loom and method for achieving substantially identical weaving cycle times
    9.
    发明授权
    Jet loom and method for achieving substantially identical weaving cycle times 失效
    喷气织机和实现基本相同的织造周期时间的方法

    公开(公告)号:US06439271B2

    公开(公告)日:2002-08-27

    申请号:US09875783

    申请日:2001-06-06

    CPC classification number: D03D47/306 D03D47/3033

    Abstract: A valve arrangement of a loom includes valve modules held between flange plates and sharing a common inlet feeding into a common inner valve space. A valve outlet of each valve module leads to an insertion nozzle or nozzle group, and is controlled by a valve disk actuated by a piezoelectric actuator to rapidly dynamically adjust the pressure profile. A quality parameter, characteristic of the thread insertion flight time of each weft thread, is stored in a data bank and has a nominal pressure profile for achieving a nominal thread flight time allocated thereto. The actual thread flight time of each weft thread is measured and compared with the stored nominal thread flight time. A control signal responsive to the time difference is provided to the valve arrangement to control the piezoelectric actuator so as to adjust the pressure and/or the quantity of the pressure medium provided through the valve module to the connected insertion nozzle. Alternatively, the control signal is provided to the main loom rotational drive to adjust the rotational speed of the loom.

    Abstract translation: 织机的阀门装置包括保持在凸缘板之间并且共用共同的入口进入公共内部阀空间的阀模块。 每个阀模块的阀出口通向插入喷嘴或喷嘴组,由压电致动器驱动的阀盘控制,以快速动态调节压力分布。 每个纬纱的螺纹插入飞行时间的特性的质量参数存储在数据库中,并且具有用于实现分配给其的公称螺纹飞行时间的标称压力分布。 测量每个纬纱的实际螺纹飞行时间,并与存储的标称螺纹飞行时间进行比较。 响应于时间差的控制信号被提供给阀装置以控制压电致动器,以便将通过阀模块提供的压力介质的压力和/或数量调节到连接的插入喷嘴。 或者,控制信号被提供到主织机旋转驱动器以调节织机的转速。

    Method and measuring apparatus for a contactless longitudinal and
transversal homogeneity examination of critical current density in
superconductor tape
    10.
    发明授权
    Method and measuring apparatus for a contactless longitudinal and transversal homogeneity examination of critical current density in superconductor tape 失效
    用于超导带中临界电流密度的非接触式纵向和横向均匀性检查的方法和测量装置

    公开(公告)号:US6034527A

    公开(公告)日:2000-03-07

    申请号:US65491

    申请日:1998-04-24

    CPC classification number: G01R33/1246 G01R33/0094

    Abstract: A method and apparatus employs Hall probes for contactless, longitudinal and transversal homogeneity examination of a critical current density j.sub.c in a superconductor tape that is cooled to below a transition temperature T.sub.c. The cooled superconductor tape is pulled through an external, locally limited magnetic field that has a constant gradient and a fixed magnetic field axis. The magnetic field generated by a screening current induced in a region of the superconductor tape penetrated by the external magnetic field is scanned using a first Hall probe at a distance of a few tenths of millimeters to the superconductor tape. The external magnetic field outside of a field range of the induced persistent currents is measured with a second Hall probe. A compensated difference between the first and second Hall probe signals is used as a qualitative measure for a critical current density j.sub.c (x) and its longitudinal homogeneity which varies locally with respect to a longitudinal axis of the superconductor tape. The compensated difference is formed by adjusting a test difference between the two Hall probe signals to zero as a result of measuring the external magnetic field by both Hall probes in a dummy measurement conducted without the superconductor tape. A transverse homogeneity with a linear Hall probe array that is positioned crosswise to the longitudinal axis of the superconductor tape and extends broadside over the superconductor tape is measured after all Hall probes in the array have first been adjusted to zero with a signal from the second probe. Quantitative locally critical current densities are specified from the Hall probe signals by a resistive calibration obtained from a current-voltage measurement.

    Abstract translation: 一种方法和装置使用霍尔探头进行非接触式,纵向和横向均匀性检查,该超临界电流密度jc在冷却至转变温度Tc以下的超导带中。 冷却的超导体带被拉动通过具有恒定梯度和固定磁场轴的外部局部受限的磁场。 通过在由外部磁场穿透的超导体带的区域中感应的屏蔽电流产生的磁场,使用距离超导体磁带的十分之几毫米的第一霍尔探头进行扫描。 用第二霍尔探头测量感应持续电流的场范围外的外部磁场。 第一和第二霍尔探测信号之间的补偿差异被用作临界电流密度jc(x)及其相对于超导带的纵轴局部变化的纵向均匀性的定性测量。 通过将两个霍尔探头信号之间的测试差调整为零,作为通过两个霍尔探针在没有超导带的虚拟测量中的外部磁场的结果来形成补偿差分。 在阵列中的所有霍尔探针首先通过来自第二探针的信号调节到零之后,测量与线性霍尔探针阵列的横向均匀性,该直线霍尔探针阵列与超导带的纵向轴线交叉定位并在超导带上延伸越过侧面 。 通过从电流 - 电压测量获得的电阻校准,从霍尔探针信号中指定定量局部临界电流密度。

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