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1.发明授权公开(公告)号：US07505130B2
公开(公告)日：2009-03-17
申请号：US11942420
申请日：2007-11-19
Applicant: David J. Brady , Scott T. McCain , Michael E. Gehm , Michael E. Sullivan , Prasant Potuluri
Inventor： David J. Brady , Scott T. McCain , Michael E. Gehm , Michael E. Sullivan , Prasant Potuluri
CPC classification number: G01J3/2846 , G01J3/02 , G01J3/0205 , G01J3/0208 , G01J3/0218 , G01J3/0229
Abstract: A class of aperture coded spectrometer is optimized for the spectral characterization of diffuse sources. The instrument achieves high throughput and high spatial resolution by replacing the slit of conventional dispersive spectrometers with a spatial filter or mask. A number of masks can be used including Harmonic masks, Legendre masks, and Hadamard masks.
Abstract translation: 一类孔径编码光谱仪针对扩散源的光谱特征进行了优化。 该仪器通过用空间滤波器或掩模代替常规色散光谱仪的狭缝，实现了高通量和高空间分辨率。 可以使用多个掩模，包括谐波掩模，Legendre面具和Hadamard面具。
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公开(公告)号：US20080059240A1
公开(公告)日：2008-03-06
申请号：US11609443
申请日：2006-12-12
Applicant: Prasant Potuluri , David Brady , Michael Fuller
Inventor： Prasant Potuluri , David Brady , Michael Fuller
CPC classification number: G06F19/3462 , G06F19/00 , G06Q50/22 , G06Q50/24
Abstract: Embodiments of the present invention relate to systems and methods for communicating pharmaceutical verification information between a server and a node using a network. A node includes a pharmaceutical identification and verification system. The verification information includes a known spectral signature of a known pharmaceutical and a corresponding known pharmaceutical name and dosage strength of the known pharmaceutical. The server stores the verification information in a server database. The node receives the verification information from the server, stores the verification information in the client database, reads a pharmaceutical name and dosage strength from a container enclosing a pharmaceutical, obtains a detected spectral signature for the pharmaceutical, and compares the detected spectral signature to the at least one known spectral signature. The pharmaceutical identification and verification system includes a static multimodal multiplex spectrometer. The verification information can also include a spectral signature of a known container.
Abstract translation: 本发明的实施例涉及用于在服务器和使用网络的节点之间传送药物验证信息的系统和方法。 节点包括药物识别和验证系统。 验证信息包括已知药物的已知光谱特征和已知药物的相应的已知药物名称和剂量强度。 服务器将验证信息存储在服务器数据库中。 节点从服务器接收验证信息，将验证信息存储在客户端数据库中，从包含药品的容器读取药品名称和剂量强度，获得检测到的药品光谱特征，并将检测到的光谱特征与 至少一个已知的光谱特征。 药物鉴定和验证系统包括静态多模式多重光谱仪。 验证信息还可以包括已知容器的光谱签名。
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公开(公告)号：US20100209004A1
公开(公告)日：2010-08-19
申请号：US12705955
申请日：2010-02-15
Applicant: Prasant Potuluri , David J. Brady
Inventor： Prasant Potuluri , David J. Brady
CPC classification number: G01N21/31 , G01N21/65 , G01N21/9508 , G01N33/15 , G01N2021/651 , G01N2201/0221
Abstract: A spectroscopic chemical compound identification system includes a container, a memory, a spectrometer, and a processor. The container receives unknown chemical compound. The memory stores a plurality of spectral signatures corresponding to known chemical compounds. The spectrometer measures a spectral signature of the unknown chemical compound through the container. The processor is connected to the memory and the spectrometer, performs a comparison of the spectral signature with at least one of the plurality of spectral signatures, and determines the identity of the unknown chemical compound from the comparison. The system can be housed in a portable handheld housing. A chemical compound can include a pharmaceutical or controlled substance. The system can be also be used to determine if a pharmaceutical or controlled substance is present within an unknown mixture of chemical compounds.
Abstract translation: 光谱化学化合物识别系统包括容器，存储器，光谱仪和处理器。 容器收到未知的化合物。 存储器存储对应于已知化合物的多个光谱特征。 光谱仪通过容器测量未知化合物的光谱特征。 处理器连接到存储器和光谱仪，执行光谱特征与多个光谱特征中的至少一个的比较，并从比较中确定未知化合物的身份。 该系统可以容纳在便携式手持式外壳中。 化合物可以包括药物或受控物质。 该系统还可用于确定未知的化合物混合物内是否存在药物或受控物质。
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公开(公告)号：US07720694B2
公开(公告)日：2010-05-18
申请号：US11609443
申请日：2006-12-12
Applicant: Prasant Potuluri , David J. Brady , Michael Fuller
Inventor： Prasant Potuluri , David J. Brady , Michael Fuller
IPC: G06Q10/00
CPC classification number: G06F19/3462 , G06F19/00 , G06Q50/22 , G06Q50/24
Abstract: Embodiments of the present invention relate to systems and methods for communicating pharmaceutical verification information between a server and a node using a network. A node includes a pharmaceutical identification and verification system. The verification information includes a known spectral signature of a known pharmaceutical and a corresponding known pharmaceutical name and dosage strength of the known pharmaceutical. The server stores the verification information in a server database. The node receives the verification information from the server, stores the verification information in the client database, reads a pharmaceutical name and dosage strength from a container enclosing a pharmaceutical, obtains a detected spectral signature for the pharmaceutical, and compares the detected spectral signature to the at least one known spectral signature. The pharmaceutical identification and verification system includes a static multimodal multiplex spectrometer. The verification information can also include a spectral signature of a known container.
Abstract translation: 本发明的实施例涉及用于在服务器和使用网络的节点之间传送药物验证信息的系统和方法。 节点包括药物识别和验证系统。 验证信息包括已知药物的已知光谱特征和已知药物的相应的已知药物名称和剂量强度。 服务器将验证信息存储在服务器数据库中。 节点从服务器接收验证信息，将验证信息存储在客户端数据库中，从包含药品的容器读取药品名称和剂量强度，获得检测到的药品光谱特征，并将检测到的光谱特征与 至少一个已知的光谱特征。 药物鉴定和验证系统包括静态多模式多重光谱仪。 验证信息还可以包括已知容器的光谱签名。
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公开(公告)号：US07616306B2
公开(公告)日：2009-11-10
申请号：US11831832
申请日：2007-07-31
Applicant: David J. Brady , Nikos Pitsianis , Xiaobai Sun , Prasant Potuluri
Inventor： David J. Brady , Nikos Pitsianis , Xiaobai Sun , Prasant Potuluri
IPC: G01J3/28
CPC classification number: G06T9/00 , H04N19/105 , H04N19/12 , H04N19/132 , H04N19/14 , H04N19/176 , H04N19/18 , H04N19/184 , H04N19/59 , H04N19/593 , H04N19/63
Abstract: An optical wavemeter includes a slit, a diffraction grating, a mask, a complementary grating, and a detector. A monochromatic source is incident on the slit. The diffraction grating produces an image of the slit in an image plane at a horizontal position that is wavelength dependent. The mask has a two-dimensional pattern of transmission variations and produces different vertical intensity channels for different spectral channels. The complementary grating produces a stationary image of the slit independent of wavelength. The detector measures vertical variations in intensity of the stationary image, and the mask is created so that the number of measurements made by the detector is less than the number of spectral channels sampled.
Abstract translation: 光波长计包括狭缝，衍射光栅，掩模，互补光栅和检测器。 单色源入射在狭缝上。 衍射光栅在波长相关的水平位置处在像平面中产生狭缝的图像。 掩模具有传输变化的二维图案，并为不同的光谱通道产生不同的垂直强度通道。 互补光栅产生独立于波长的狭缝的静止图像。 检测器测量静止图像的强度的垂直变化，并且创建掩模，使得由检测器进行的测量的数量小于采样的频谱通道的数量。
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Patent Agency Ranking
公开(公告)号：US07463179B2
公开(公告)日：2008-12-09
申请号：US11831855
申请日：2007-07-31
Applicant: David J. Brady , Nikos Pitsianis , Xiaobai Sun , Prasant Potuluri
Inventor： David J. Brady , Nikos Pitsianis , Xiaobai Sun , Prasant Potuluri
IPC: H03M1/12
CPC classification number: G06T9/00 , H04N19/105 , H04N19/12 , H04N19/132 , H04N19/14 , H04N19/176 , H04N19/18 , H04N19/184 , H04N19/59 , H04N19/593 , H04N19/63
Abstract: An optical signal is compressively sampled using an optical component to encode multiplex measurements. A mapping from the optical signal to a detector array is created using spatial and/or spectral dispersion. Signals transmitted by a plurality of transmissive elements of the optical component are detected at each sensor of a plurality of sensors of the detector array dispersed spatially with respect to the optical component. Each sensor of a plurality of sensors produces a measurement resulting in a number of measurements. A number of estimated optical signal values is calculated from the number of measurements and a transmission function. The transmission function is selected so that the number of measurements is less than the number of estimated optical signal values.
Abstract translation: 使用光学部件对光信号进行压缩采样以对多重测量进行编码。 使用空间和/或光谱色散创建从光信号到检测器阵列的映射。 在相对于光学部件在空间上分散的检测器阵列的多个传感器的每个传感器的每个传感器处检测由光学部件的多个透射元件发送的信号。 多个传感器中的每个传感器产生测量，导致多个测量。 根据测量次数和传输函数计算出多个估计的光信号值。 选择发送功能，使得测量次数小于估计的光信号值的数量。
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公开(公告)号：US07379181B2
公开(公告)日：2008-05-27
申请号：US11421903
申请日：2006-06-02
Applicant: David J. Brady , Prasant Potuluri , Michael E. Sullivan
Inventor： David J. Brady , Prasant Potuluri , Michael E. Sullivan
CPC classification number: G01J3/02 , G01J3/0216 , G01J3/0218 , G01J3/0221 , G01J3/0229 , G01J3/2803 , G01J3/2846 , G02B2207/129
Abstract: A spatial filter for an optical system, such as an optical spectrometer, collects and spatially filters light using a fiber bundle having a plurality of fibers disposed therein. At an input end of the fiber bundle, the fibers are typically packed tightly together to optimize the collection efficiency. At an output end, the fibers are spread out from the fiber bundle and arranged within a two-dimensional output area according to a two-dimensional pattern corresponding to a coded aperture function. As a result, the two-dimensional pattern of the output end spatially filters the light collected by the input end. Corresponding methods are also described.
Abstract translation: 用于诸如光谱仪的光学系统的空间滤光器使用其中布置有多个光纤的纤维束聚集并空间地过滤光。 在纤维束的输入端，通常将纤维紧密地包装在一起以优化收集效率。 在输出端，根据与编码孔径函数对应的二维图案，纤维从纤维束展开并布置在二维输出区域内。 结果，输出端的二维图案对输入端收集的光进行空间滤波。 还描述了相应的方法。
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公开(公告)号：US20070165220A1
公开(公告)日：2007-07-19
申请号：US11421903
申请日：2006-06-02
Applicant: David J. Brady , Prasant Potuluri , Michael E. Sullivan
Inventor： David J. Brady , Prasant Potuluri , Michael E. Sullivan
IPC: G01J3/04
CPC classification number: G01J3/02 , G01J3/0216 , G01J3/0218 , G01J3/0221 , G01J3/0229 , G01J3/2803 , G01J3/2846 , G02B2207/129
Abstract: A spatial filter for an optical system, such as an optical spectrometer, collects and spatially filters light using a fiber bundle having a plurality of fibers disposed therein. At an input end of the fiber bundle, the fibers are typically packed tightly together to optimize the collection efficiency. At an output end, the fibers are spread out from the fiber bundle and arranged within a two-dimensional output area according to a two-dimensional pattern corresponding to a coded aperture function. As a result, the two-dimensional pattern of the output end spatially filters the light collected by the input end. Corresponding methods are also described.
Abstract translation: 用于诸如光谱仪的光学系统的空间滤光器使用其中布置有多根纤维的纤维束聚集并空间地过滤光。 在纤维束的输入端，通常将纤维紧密包装在一起，以优化收集效率。 在输出端，根据与编码孔径函数对应的二维图案，纤维从纤维束展开并布置在二维输出区域内。 结果，输出端的二维图案对输入端收集的光进行空间滤波。 还描述了相应的方法。
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公开(公告)号：US07218395B2
公开(公告)日：2007-05-15
申请号：US11454923
申请日：2006-06-19
Applicant: Stephen T. Kaye , Prasant Potuluri , David J. Brady , Michael Fuller , Michael E. Sullivan
Inventor： Stephen T. Kaye , Prasant Potuluri , David J. Brady , Michael Fuller , Michael E. Sullivan
CPC classification number: G01J3/44 , B07C5/344 , G01J3/02 , G01J3/0264 , G01J3/28 , G01J3/2846 , G01J2003/4424 , G01N21/3563 , G01N21/3577 , G01N21/359 , G01N21/65 , G01N21/9508 , G01N2021/3595 , G01N2021/651 , G01N2201/129
Abstract: A prescription verification system includes a database that contains a plurality of spectral signatures corresponding to identified pharmaceuticals. A multimodal multiplex sampling (MMS) spectrometer obtains a spectra of a pharmaceutical to be identified and verified. The pharmaceutical can be inside or out of a vial. The prescription verification system includes algorithms for matching spectra of pharmaceuticals to be verified obtaining using the MMS spectrometer to spectral signatures contained in the database corresponding to identified pharmaceuticals. The prescription verification system further includes algorithms for identifying such pharmaceuticals to be verified.
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公开(公告)号：US08731959B2
公开(公告)日：2014-05-20
申请号：US12705955
申请日：2010-02-15
Applicant: Prasant Potuluri , David J. Brady
Inventor： Prasant Potuluri , David J. Brady
CPC classification number: G01N21/31 , G01N21/65 , G01N21/9508 , G01N33/15 , G01N2021/651 , G01N2201/0221
Abstract: A spectroscopic chemical compound identification system includes a container, a memory, a spectrometer, and a processor. The container receives unknown chemical compound. The memory stores a plurality of spectral signatures corresponding to known chemical compounds. The spectrometer measures a spectral signature of the unknown chemical compound through the container. The processor is connected to the memory and the spectrometer, performs a comparison of the spectral signature with at least one of the plurality of spectral signatures, and determines the identity of the unknown chemical compound from the comparison. The system can be housed in a portable handheld housing. A chemical compound can include a pharmaceutical or controlled substance. The system can be also be used to determine if a pharmaceutical or controlled substance is present within an unknown mixture of chemical compounds.
Abstract translation: 光谱化学化合物识别系统包括容器，存储器，光谱仪和处理器。 容器收到未知的化合物。 存储器存储对应于已知化合物的多个光谱特征。 光谱仪通过容器测量未知化合物的光谱特征。 处理器连接到存储器和光谱仪，执行光谱特征与多个光谱特征中的至少一个的比较，并从比较中确定未知化合物的身份。 该系统可以容纳在便携式手持式外壳中。 化合物可以包括药物或受控物质。 该系统还可用于确定未知的化合物混合物内是否存在药物或受控物质。
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