公开(公告)号：US20230052697A1

公开(公告)日：2023-02-16

申请号：US17710756

申请日：2022-03-31

申请人： Progenity, Inc.

发明人： Pankaj OBEROI ,  Sharat SINGH ,  Amin MAZLOOM

IPC分类号： G01N33/537 ,  G01N33/68 ,  G01N33/74

摘要： Described herein are methods, compositions, kits, and systems for detecting free and bound PlGF, and using detection of such species to distinguish between pregnant women with or without preeclampsia or related conditions.

公开(公告)号：US20230041197A1

公开(公告)日：2023-02-09

申请号：US17253799

申请日：2019-06-19

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Sharat Singh ,  Christopher Loren Wahl ,  Harry Stylli ,  Kevin David Howe ,  Arana Perera

IPC分类号： A61M31/00 ,  A61K38/19

摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immunomodulator.

公开(公告)号：US11363964B2

公开(公告)日：2022-06-21

申请号：US15940407

申请日：2018-03-29

申请人： Progenity Inc.

发明人： Mitchell Lawrence Jones ,  Yi Liu ,  Kate LeeAnn Bechtel ,  Christopher Loren Wahl

IPC分类号： A61B5/06 ,  A61B5/00 ,  A61B5/07 ,  G16H40/67 ,  A61B5/11 ,  A61B10/00

摘要： Ingestible devices are disclosed that provide very high localization accuracy for the devices when present in the GI tract of a body. Related systems and methods are also disclosed.

公开(公告)号：US20220135666A1

公开(公告)日：2022-05-05

申请号：US16769983

申请日：2018-12-13

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Sharat Singh ,  Christopher Loren Wahl ,  Harry Stylli ,  Kevin David Howe ,  Aruna Perera

IPC分类号： C07K16/24 ,  A61K31/4196 ,  A61K31/4245 ,  A61K31/428 ,  A61K31/436 ,  A61K31/519 ,  A61K31/606 ,  A61K38/08 ,  A61K38/13 ,  A61K9/48 ,  C07K16/28 ,  A61K9/19 ,  A61K31/573

摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a S1P modulator.

公开(公告)号：US11241562B2

公开(公告)日：2022-02-08

申请号：US16299537

申请日：2019-03-12

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Russell B. Ford ,  Edward G. Solomon ,  Jeffrey A. Shimizu

IPC分类号： A61M31/00 ,  A61B10/00 ,  A61B10/02 ,  A61B5/00 ,  A61K9/00 ,  A61B1/04 ,  A61B10/04

摘要： Ingestible devices with a relatively large payload volume or sample volume, as well as related components, systems and methods, are disclosed.

公开(公告)号：US20210373001A1

公开(公告)日：2021-12-02

申请号：US17393708

申请日：2021-08-04

申请人： Progenity, Inc.

发明人： Pankaj OBEROI ,  Sharat SINGH ,  Amin MAZLOOM

IPC分类号： G01N33/537 ,  G01N33/68 ,  G01N33/74

摘要： Described herein are methods, compositions, kits, and systems for detecting free and bound PlGF, and using detection of such species to distinguish between pregnant women with or without preeclampsia or related conditions.

公开(公告)号：US20210138213A1

公开(公告)日：2021-05-13

申请号：US16496791

申请日：2018-03-30

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Sharat Singh ,  Christopher Loren Wahl ,  Harry Stylli

IPC分类号： A61M31/00 ,  A61K9/00 ,  A61P1/04 ,  C07K16/24 ,  A61K31/436 ,  A61K9/48 ,  C07K16/28 ,  A61K38/13 ,  C12N15/113

摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with an immune modulatory agent (e.g., a CD40/CD40L inhibitor).

公开(公告)号：US20200264188A1

公开(公告)日：2020-08-20

申请号：US16646552

申请日：2018-09-13

申请人： PROGENITY, INC.

发明人： Matthew COOPER ,  Sharat SINGH ,  Karen A.F. COPELAND ,  Lyndal HESTERBERG ,  Amin R. MAZLOOM ,  Mohammad ABBASI ,  Richard Giulio DEL MASTRO

IPC分类号： G01N33/68 ,  G16B25/10 ,  G01N33/543 ,  A61K31/166 ,  A61K31/4422 ,  A61K31/277 ,  A61K31/4168 ,  A61K31/502 ,  A61K31/198 ,  A61K31/549 ,  A61K31/517 ,  A61K31/138

摘要： Disclosed herein are methods, kits, tests, and systems for detecting, predicting, monitoring, or ruling out preeclampsia in pregnant women. Also provided herein are novel diagnostic markers, methods of data analysis, assay formats, and kits employing such markers to improve one or more characteristics of a test for identifying or ruling out preeclampsia based on biomarkers from patient samples.

公开(公告)号：US20200245897A1

公开(公告)日：2020-08-06

申请号：US16839107

申请日：2020-04-03

申请人： Progenity, Inc.

发明人： Mitchell Lawrence Jones ,  Christopher Loren Wahl ,  Gene Alan Wey ,  Aaron Olafur Laurence Philippsen ,  Mark Sasha Drlik ,  Iman Niknia

IPC分类号： A61B5/07 ,  A61B1/04 ,  A61M31/00

摘要： Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

公开(公告)号：US20200221954A1

公开(公告)日：2020-07-16

申请号：US16827807

申请日：2020-03-24

申请人： Progenity, Inc.

发明人： Sharat Singh ,  Mitchell Lawrence Jones ,  Christopher Loren Wahl

IPC分类号： A61B5/00 ,  A61B10/00 ,  A61K45/06 ,  A61K49/00 ,  C12M1/00 ,  C12N1/20 ,  C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  G01N1/10 ,  G01N1/20 ,  G01N1/38 ,  G01N21/76 ,  G01N33/487 ,  G01N33/483 ,  G01N33/58 ,  A61B5/07

摘要： The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.