公开(公告)号：US06579862B1

公开(公告)日：2003-06-17

申请号：US09280448

申请日：1999-03-30

申请人： Ram Pratap ,  Ram Chandra Gupta ,  Ramesh Chander ,  Ashok Kumar Khanna ,  Arvind Kumar Srivastava ,  Deepak Raina ,  Satyavan Singh ,  Savita Srivastava ,  Anil Kumar Rastogi ,  Omkar Prasad Asthana ,  Swarn Nityanand ,  Nitya Anand ,  Ashim Ghatak ,  Narinder Kumar Kapoor ,  Sukh Dev

发明人： Ram Pratap ,  Ram Chandra Gupta ,  Ramesh Chander ,  Ashok Kumar Khanna ,  Arvind Kumar Srivastava ,  Deepak Raina ,  Satyavan Singh ,  Savita Srivastava ,  Anil Kumar Rastogi ,  Omkar Prasad Asthana ,  Swarn Nityanand ,  Nitya Anand ,  Ashim Ghatak ,  Narinder Kumar Kapoor ,  Sukh Dev

IPC分类号： A61K3158

CPC分类号： A61K31/573 ,  C07J13/005 ,  C07J13/007

摘要： The invention provides a method of using pregnadienones and pregnadienols represented by the structural formula (I): containing at least one olefinic bond in or on their D-ring for the treatment of hyperlipidemic and hyperglycemic conditions in mammals wherein X═OH or O and the olefinic bonds are at 4(5); 5(6); 16(17); or 17(20) or various combinations, and wherein the compounds contain at lest one olefinic bond in or on their D-ring. The method comprises administering an effective amount of said compounds to recipient mammals.

摘要翻译： 本发明提供了一种使用由结构式（I）表示的孕ad酮和孕二烯醇的方法：在D环中或其D环上含有至少一个烯键，用于治疗哺乳动物中的高脂血症和高血糖病症，其中X = OH或O， 烯键为4（5）; 5（6）; 16（17）; 或17（20）或各种组合，并且其中所述化合物在其D环中或其上含有至少一个烯键。 该方法包括向受体哺乳动物施用有效量的所述化合物。

公开(公告)号：US20120071649A1

公开(公告)日：2012-03-22

申请号：US13254416

申请日：2010-03-04

申请人： Venugopal Venkatarama Durvasula ,  Parendu Dhirajlal Rathod ,  Ram Chandra Aryan ,  Chandra Has Khanduri

发明人： Venugopal Venkatarama Durvasula ,  Parendu Dhirajlal Rathod ,  Ram Chandra Aryan ,  Chandra Has Khanduri

IPC分类号： C07D417/04

CPC分类号： C07D281/16

摘要： The present invention relates to an improved process for the preparation of quetiapine and pharmaceutically acceptable salts. It also relates to improved process for the preparation of intermediates of quetiapine.

摘要翻译： 本发明涉及一种制备喹硫平和药学上可接受的盐的改进方法。 它还涉及改进制备喹硫平中间体的方法。

公开(公告)号：US20060031957A1

公开(公告)日：2006-02-09

申请号：US10913792

申请日：2004-08-06

申请人： Suman Khanuja ,  Raj Lal ,  Arun Agnihotri ,  Ajit Shasany ,  Ali Naqvi ,  Samresh Dwivedi ,  Hari Misra ,  Om Dhawan ,  Alok Kalra ,  Aparbal Singh ,  Janak Bahl ,  Saudan Singh ,  Dharani Patra ,  Shilpi Agarwal ,  Mahendra Darokar ,  Anil Gupta ,  Moti Gupta ,  Ram Chandra

发明人： Suman Khanuja ,  Raj Lal ,  Arun Agnihotri ,  Ajit Shasany ,  Ali Naqvi ,  Samresh Dwivedi ,  Hari Misra ,  Om Dhawan ,  Alok Kalra ,  Aparbal Singh ,  Janak Bahl ,  Saudan Singh ,  Dharani Patra ,  Shilpi Agarwal ,  Mahendra Darokar ,  Anil Gupta ,  Moti Gupta ,  Ram Chandra

IPC分类号： A01H1/02

CPC分类号： A01H5/12

摘要： Indian basil, Ocimum basilicum, belongs to the family of Lamiaceae. The essential oil of Indian basil extracted via hydro or steam distillation from the leaves or whole plants is used to flavour foods, dental and oral products, in fragrances, and in traditional rituals and medicines. Extracted essential oil has also been shown to contain biologically active constituents that are insecticidal, nematicidal, fungistatic or which have antimicrobial properties. The present invention relates to the development of an early, short duration, dwarf, high essential oil, methyl chavicol and linalool yielding variety of Indian basil (Ocimum basilicum), Family—Lamiaceae) named as ‘CIM-SAUMYA’. This new variety of Indian basil was developed through open pollination in the germplasm followed by half-sib progeny selection and evaluation for the yield characters of selected population for 3 years in field conditions. The new cultivar possesses better growth and vegetative growth and is able to produce higher herbage, oil and better combination of methyl chavicol and linalool yield per unit area as compared to other control genotypes

摘要翻译： 印度罗勒，罗勒属，属于百叶科科。 通过水蒸气或蒸汽蒸馏从叶子或整个植物中提取的印度罗勒香精油用于调味香料中的食物，牙科和口服产品，以及传统的仪式和药物。 提取的精油也显示含有具有杀虫，杀线虫，抑菌或具有抗微生物特性的生物活性成分。 本发明涉及被命名为“CIM-SAUMYA”的印度罗勒（Ocaly basilicum）的家族 - 唇形科的早期，短期，矮化，高精油，甲基辣椒素和芳樟醇产生品种的开发。 这种新种类的印度罗勒是通过在种质上的开放授粉开发的，然后进行半同胞后代选择，并对现场条件下所选群体的产量特征进行评估3年。 与其他对照基因型相比，新品种具有更好的生长和营养生长，能够产生更高的草药，油和更好的单位面积甲基切维醇和芳樟醇产量的组合

公开(公告)号：US06875758B2

公开(公告)日：2005-04-05

申请号：US10385936

申请日：2003-03-14

申请人： Ram Pratap ,  Ram Chandra Gupta ,  Ramesh Chander ,  Ashok Kumar Khanna ,  Arvind Kumar Srivastava ,  Deepak Raina ,  Satyavan Singh ,  Savita Srivastava ,  Anil Kumar Rastogi ,  Omkar Prasad Asthana ,  Swarn Nityanand ,  Nitya Anand ,  Ashim Ghatak ,  Narinder Kumar Kapoor ,  Sukh Dev

发明人： Ram Pratap ,  Ram Chandra Gupta ,  Ramesh Chander ,  Ashok Kumar Khanna ,  Arvind Kumar Srivastava ,  Deepak Raina ,  Satyavan Singh ,  Savita Srivastava ,  Anil Kumar Rastogi ,  Omkar Prasad Asthana ,  Swarn Nityanand ,  Nitya Anand ,  Ashim Ghatak ,  Narinder Kumar Kapoor ,  Sukh Dev

IPC分类号： C07J13/00 ,  A61K31/56 ,  A61K31/59

CPC分类号： A61K31/573 ,  C07J13/005 ,  C07J13/007

摘要： The invention provides a method of using pregnadienones and pregnadienols represented by the structural formula (I) as shown herein below Wherein X═OH or O or combination thereof and positioning of olefinic bonds are at 4(5); 5(6); 16(17); 17(20) or various combinations and said compounds containing at least one olefinic bond in or on their D-ring for the treatment of hyperlipidemic and hyperglycemic conditions in mammals, said method comprising administering an effective amount of the said compounds to the recipient mammals.

摘要翻译： 本发明提供了一种使用由下式结构式（I）表示的孕ad酮和孕二烯醇的方法，其中X = OH或O或其组合，烯键的定位为4（5）; 5（6）; 16（17）; 17（20）或各种组合，并且所述化合物在其D环上或其D环上含有至少一个烯键，用于治疗哺乳动物中的高脂血症和高血糖病症，所述方法包括向受体哺乳动物施用有效量的所述化合物。

公开(公告)号：US5961818A

公开(公告)日：1999-10-05

申请号：US282979

申请日：1999-03-31

申请人： Ajit Ram Chandra Pradhan ,  Nagabhatla Viswanadham ,  Mohan Lal Sharma ,  Uma Shanker ,  Nirmalya Ray ,  Turuga Sundara Rama Prasada Rao

发明人： Ajit Ram Chandra Pradhan ,  Nagabhatla Viswanadham ,  Mohan Lal Sharma ,  Uma Shanker ,  Nirmalya Ray ,  Turuga Sundara Rama Prasada Rao

IPC分类号： B01J29/40 ,  C10G11/05 ,  C10G35/06 ,  C10G35/095

CPC分类号： C10G35/095 ,  B01J29/405 ,  C10G35/065 ,  B01J2229/26 ,  B01J2229/42 ,  C10G2400/28 ,  C10G2400/30

摘要： The present invention relates to a process for production of LPG and high octane aromatic hydrocarbon from non-economically viable petroleum feedstock, which comprises passing the same feedstock through zinc-aluminosilicate molecular sieve (Zn-ZSM-5), in a reactor at a temperature in the range of 300-600.degree. C. pressure 1 to 30 atmosphere liquid hourly space velocity of 1 to 10 hr.sup.-1 and nitrogen to hydrocarbon molar ratio 1 to 4.

摘要翻译： 本发明涉及从非经济上可行的石油原料生产液化石油气和高辛烷值芳烃的方法，该方法包括使相同的原料通过锌 - 铝硅酸盐分子筛（Zn-ZSM-5），在反应器中温度 在300-600℃的压力范围内，压力为1〜30个大气压，时空速度为1〜10小时-1，氮与烃的摩尔比为1〜4。

公开(公告)号：US07435877B2

公开(公告)日：2008-10-14

申请号：US10913792

申请日：2004-08-06

申请人： Suman Preet Singh Khanuja ,  Raj Kishori Lal ,  Arun Kumar Agnihotri ,  Ajit Kumar Shasany ,  Ali Arif Naqvi ,  Samresh Dwivedi ,  Hari Om Misra ,  Om Prakesh Dhawan ,  Alok Kalra ,  Aparbal Singh ,  Janak Raj Bahl ,  Saudan Singh ,  Dharani Dhar Patra ,  Shilpi Agarwal ,  Mahendra Pandurang Darokar ,  Anil Kumar Gupta ,  Moti Lal Gupta ,  Ram Chandra

发明人： Suman Preet Singh Khanuja ,  Raj Kishori Lal ,  Arun Kumar Agnihotri ,  Ajit Kumar Shasany ,  Ali Arif Naqvi ,  Samresh Dwivedi ,  Hari Om Misra ,  Om Prakesh Dhawan ,  Alok Kalra ,  Aparbal Singh ,  Janak Raj Bahl ,  Saudan Singh ,  Dharani Dhar Patra ,  Shilpi Agarwal ,  Mahendra Pandurang Darokar ,  Anil Kumar Gupta ,  Moti Lal Gupta ,  Ram Chandra

IPC分类号： A01H5/00 ,  A01H5/10

CPC分类号： A01H5/12

摘要： Indian basil, Ocimum basilicum, belongs to the family of Lamiaceae. The essential oil of Indian basil extracted via hydro or steam distillation from the leaves or whole plants is used to flavor foods, dental and oral products, in fragrances, and in traditional rituals and medicines. Extracted essential oil has also been shown to contain biologically active constituents that are insecticidal, nematicidal, fungistatic or which have antimicrobial properties. The present invention relates to the development of an early, short duration, dwarf, high essential oil, methy chavicol and linalool yielding variety of Indian basil (Ocimum basilicum). Family—Lamiaceae) named as ‘CIM-SAUMYA’. This new variety of Indian basil was developed through open pollination in the germplasm followed by half-sib progeny selection and evaluation for the yield characters of selected population for 3 years in field conditions. The new cultivar possesses better growth and vegetative growth and is able to produce higher herbage, oil and better combination of methyl chavicol and linalool yield per unit area as compared to other control genotypes.

摘要翻译： 印度罗勒，罗勒属，属于百叶科科。 通过水蒸气或蒸汽蒸馏从叶子或整个植物中提取的印度罗勒香精油用于调味香料中的食物，牙科和口服产品，以及传统的仪式和药物。 提取的精油也显示含有具有杀虫，杀线虫，抑菌或具有抗微生物特性的生物活性成分。 本发明涉及印度罗勒（Ocimum basilicum）的早期，短期，矮化，高精油，甲基切瓦克醇和里哪醇生产品种的发展。 名为“CIM-SAUMYA”的家庭 - 唇形科）。 这种新种类的印度罗勒是通过在种质上的开放授粉开发的，然后进行半同胞后代选择，并对现场条件下所选群体的产量特征进行评估3年。 与其他对照基因型相比，新品种具有更好的生长和营养生长，能够产生更高的草药，油和更好的单位面积甲基切维醇和芳樟醇产量的组合。

公开(公告)号：US07404962B1

公开(公告)日：2008-07-29

申请号：US10296215

申请日：2000-08-30

申请人： Francis Joseph Pinto ,  Swati Ajay Piramal ,  Ram Pratap ,  Amiya Prasad Bhaduri ,  Harsh Pati Thapliyal ,  Sunil Kumar Puri ,  Guru Prasad Dutta ,  Anil Kumar Dwivedi ,  Satyawan Singh ,  Pratima Srivastava ,  Vikash Chandra Pandey ,  Sudhir Srivastava ,  Shio Kumar Singh ,  Ram Chandra Gupta ,  Jagdishwar Sahai Srivastava ,  Omkar Prasad Asthana

发明人： Francis Joseph Pinto ,  Swati Ajay Piramal ,  Ram Pratap ,  Amiya Prasad Bhaduri ,  Harsh Pati Thapliyal ,  Sunil Kumar Puri ,  Guru Prasad Dutta ,  Anil Kumar Dwivedi ,  Satyawan Singh ,  Pratima Srivastava ,  Vikash Chandra Pandey ,  Sudhir Srivastava ,  Shio Kumar Singh ,  Ram Chandra Gupta ,  Jagdishwar Sahai Srivastava ,  Omkar Prasad Asthana

IPC分类号： A61K39/015 ,  C07D215/38

CPC分类号： A61K31/4706 ,  A61K31/47 ,  Y02A50/411 ,  A61K2300/00

摘要： A combination kit for the treatment of malaria caused by Plasmodium vivax (P. vivax) having individual doses of an anti-malarial agent, 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I) in the form of capsules; individual doses of the anti-malarial agent, chloroquine in the form of tablets; and instruction material for the administration of the two anti-malarial drugs. The combination kit is particularly suited for a 6 days treatment regimen where the treatment is rendered by five tablets containing 500 mg of chloroquine phosphate (equivalent to 300 mg base), three to be taken on day one and one each on days two and three; and five capsules containing 25 mg of 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I), one each to be taken on days two to six.

摘要翻译： 用于治疗由间日疟原虫（间日疟原虫）引起的疟疾的组合试剂盒，其具有单个剂量的抗疟剂，3- [1 - [[4 - [（6-甲氧基-8-喹啉基）氨基]戊基] 氨基]亚乙基] - 二氢-2（3H） - 呋喃酮（I） 单剂量的抗疟剂，片剂形式的氯喹; 以及两种抗疟药物的管理指导材料。 组合试剂盒特别适用于6天的治疗方案，其中使用含有500mg磷酸氯喹（相当于300mg碱）的五片，第三天服用三次，第二天和第三次服用一次; 和5粒含有25mg 3- [1 - [[4 - [（6-甲氧基-8-喹啉基）氨基]戊基]氨基]亚乙基] - 二氢-2（3H） - 呋喃酮（I）的胶囊， 在二至六天内服用。

公开(公告)号：US06730838B1

公开(公告)日：2004-05-04

申请号：US09276720

申请日：1999-03-26

申请人： Jawahar Ram Sharma ,  Raj Kishori Lal ,  Ajai Prakash Gupta ,  Hari Om Misra ,  Vasudha Pant ,  Ram Chandra ,  Mohd Rashid

发明人： Jawahar Ram Sharma ,  Raj Kishori Lal ,  Ajai Prakash Gupta ,  Hari Om Misra ,  Vasudha Pant ,  Ram Chandra ,  Mohd Rashid

IPC分类号： A01H100

CPC分类号： A01H5/10 ,  A01H5/02

摘要： The present invention relates to an opiumless and alkaloid-free non-narcotic opium poppy designated as var. Sujata having the following morphological/argonomic features: Days to 50% flowering 100-105 Plant height (cm)  80-100 Peduncle length (cm)  18-20 Peduncle colour Patchy-black No. of capsules/branches per plant  3-4 Capsule shape Flat Capsule surface ˜glabrous (white bloom +) No. of stigmatic rays per capsule  10-12 Shape and size of stigmatic rays slightly small, flattened Latex-flow on incision Absent Seed count per gram of weight 3040-3310 Seed colour Dull-white Seed shape Reniform Seed size Bold (Thickness ++) Seed yield (g/m2) 120-140 Straw yield (g/m2) 135-150 (Capsule hulls) Opium alkaloids in straw Absent.

摘要翻译： 本发明涉及一种无鸦片和无生物碱的非麻醉罂粟，称为var。 Sujata具有以下形态/神经元特征：

公开(公告)号：US20140121233A1

公开(公告)日：2014-05-01

申请号：US14124169

申请日：2012-06-11

申请人： Ritu Aneja ,  Ram Chandra Mishra

发明人： Ritu Aneja ,  Ram Chandra Mishra

IPC分类号： C07D491/056

CPC分类号： C07D491/056 ,  C07D491/04

摘要： Compound of Formula (I) and use thereof as microtubule modulating agents in the treatment of cancer are described herein.

摘要翻译： 本文描述了式（I）的化合物及其作为治疗癌症的微管调节剂的用途。

公开(公告)号：US07183291B2

公开(公告)日：2007-02-27

申请号：US09316313

申请日：1999-05-21

申请人： Ram Pratap ,  Amiya Prasad Bhaduri ,  Harsh Pati Thapliyal ,  Sunil Kumar Puri ,  Guru Prasad Dutta ,  Anil Kumar Dwivedi ,  Satyawan Singh ,  Pratima Srivastava ,  Vikash Chandra Pandey ,  Sudhir Srivastava ,  Shio Kumar Singh ,  Ram Chandra Gupta ,  Jagdishwar Sahai Srivastava ,  Omkar Prasad Asthana

发明人： Ram Pratap ,  Amiya Prasad Bhaduri ,  Harsh Pati Thapliyal ,  Sunil Kumar Puri ,  Guru Prasad Dutta ,  Anil Kumar Dwivedi ,  Satyawan Singh ,  Pratima Srivastava ,  Vikash Chandra Pandey ,  Sudhir Srivastava ,  Shio Kumar Singh ,  Ram Chandra Gupta ,  Jagdishwar Sahai Srivastava ,  Omkar Prasad Asthana

IPC分类号： C07D215/38 ,  A61K31/4709

CPC分类号： C07D405/12 ,  A61K31/4709 ,  Y02A50/411

摘要： The present invention a novel use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine in the treatment and controlling the spread of malaria. In particular, the present invention discloses a method of treatment of malaria by the use of primaquine derivative N1-(3-ethylidinotetrahydrofuran-2-one)-N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine as a gametocytocidal agent.

摘要翻译： 本发明提供了一种新颖的使用伯氨基衍生物N - （3-乙基吡啶四氢呋喃-2-酮）-N 4 - （6-甲氧基-8-喹啉基）-1 ，4-戊二胺治疗和控制疟疾传播。 特别地，本发明公开了一种通过使用伯氨基衍生物N 1 - （3-乙基吡啶四氢呋喃-2-酮）-N 4 - （ 6-甲氧基-8-喹啉基）-1,4-戊二胺作为杀丝菌剂。