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公开(公告)号：US20180355407A1
公开(公告)日：2018-12-13
申请号：US15579834
申请日：2016-06-27
IPC分类号： C12Q1/6806 , B01L3/00
CPC分类号： C12Q1/6806 , B01L3/502738 , B01L3/502761 , B01L3/502784 , B01L7/52 , B01L2200/027 , B01L2200/141 , B01L2300/021 , B01L2400/0424 , B01L2400/0436 , B01L2400/0439 , B01L2400/0487 , B01L2400/06 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629
摘要： The present invention relates to the field of microfluidics and in particular to methods for co-localizing a particle comprising DNA and/or RNA with a known barcode oligonucleotide. Thereby, the transcriptome or DNA of a cell can be barcoded and correlated to a cell phenotype or examined for the effect of a drug on the cell. The invention also provides microfluidic devices and systems having properties which make them particularly suitable for use in the methods of the invention.
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公开(公告)号：US20180095014A1
公开(公告)日：2018-04-05
申请号：US15727465
申请日：2017-10-06
申请人： Christoph Merten , Ramesh Utharala
发明人： Christoph Merten , Ramesh Utharala
IPC分类号： G01N1/28
CPC分类号： G01N1/28 , B01L3/502784 , B01L2200/026 , B01L2200/061 , B01L2200/0673 , B01L2200/0694 , B01L2300/0816 , B01L2400/0481 , B01L2400/0487 , G01J3/46 , G01J2003/466 , Y10T137/0318 , Y10T137/469 , Y10T137/877
摘要： An apparatus and a method for providing one or more substance liquids to a microfluidic channel network (30). The microfluidic apparatus includes valves for switching the one or more substance liquids to a microfluidic channel network (30). The apparatus can be used to generate a sequence of the one or more substance liquids as individual droplets in an immiscible separation liquid wherein individual ones of the sequence of droplets are located between the separation liquid.
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公开(公告)号：US20140332083A1
公开(公告)日：2014-11-13
申请号：US14344478
申请日：2012-09-14
申请人： Christoph Merten , Ramesh Utharala
发明人： Christoph Merten , Ramesh Utharala
CPC分类号： G01N1/28 , B01L3/502784 , B01L2200/026 , B01L2200/061 , B01L2200/0673 , B01L2200/0694 , B01L2300/0816 , B01L2400/0481 , B01L2400/0487 , G01J3/46 , G01J2003/466 , Y10T137/0318 , Y10T137/469 , Y10T137/877
摘要： The present disclosure teaches an apparatus and a method for providing one or more substance liquids to a microfluidic channel network (30). The microfluidic apparatus includes valves for switching the one or more substance liquids to a microfluidic channel network (30). The apparatus can be used to generate a sequence of the one or more substance liquids as individual droplets in an immiscible separation liquid wherein individual ones of the sequence of droplets are located between the separation liquid.
摘要翻译： 本公开教导了一种用于向微流体通道网络（30）提供一种或多种物质液体的装置和方法。 微流体装置包括用于将一种或多种物质液体切换到微流体通道网络（30）的阀。 该装置可用于在不混溶的分离液体中产生作为单独液滴的一种或多种物质液体的序列，其中液滴序列中的单个液滴位于分离液体之间。
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公开(公告)号：US10215671B2
公开(公告)日：2019-02-26
申请号：US15727465
申请日：2017-10-06
申请人： Christoph Merten , Ramesh Utharala
发明人： Christoph Merten , Ramesh Utharala
摘要： An apparatus and a method for providing one or more substance liquids to a microfluidic channel network (30). The microfluidic apparatus includes valves for switching the one or more substance liquids to a microfluidic channel network (30). The apparatus can be used to generate a sequence of the one or more substance liquids as individual droplets in an immiscible separation liquid wherein individual ones of the sequence of droplets are located between the separation liquid.
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公开(公告)号：US09810607B2
公开(公告)日：2017-11-07
申请号：US14344478
申请日：2012-09-14
申请人： Christoph Merten , Ramesh Utharala
发明人： Christoph Merten , Ramesh Utharala
CPC分类号： G01N1/28 , B01L3/502784 , B01L2200/026 , B01L2200/061 , B01L2200/0673 , B01L2200/0694 , B01L2300/0816 , B01L2400/0481 , B01L2400/0487 , G01J3/46 , G01J2003/466 , Y10T137/0318 , Y10T137/469 , Y10T137/877
摘要： The present disclosure teaches an apparatus and a method for providing one or more substance liquids to a microfluidic channel network (30). The microfluidic apparatus includes valves for switching the one or more substance liquids to a microfluidic channel network (30). The apparatus can be used to generate a sequence of the one or more substance liquids as individual droplets in an immiscible separation liquid wherein individual ones of the sequence of droplets are located between the separation liquid.
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