公开(公告)号：US08975067B2

公开(公告)日：2015-03-10

申请号：US13995524

申请日：2011-12-20

Applicant: William E. Foltz ,  Francois Ahimou ,  G. Marco Bommarito ,  Robert A. Asmus ,  Louis C. Haddad ,  Tushar A. Kshirsagar

Inventor： William E. Foltz ,  Francois Ahimou ,  G. Marco Bommarito ,  Robert A. Asmus ,  Louis C. Haddad ,  Tushar A. Kshirsagar

IPC: C12M3/00

CPC classification number: C12Q1/22 ,  C12Q1/25 ,  G01N21/78 ,  G01N31/226 ,  G01N33/573 ,  G01N2021/7786 ,  G01N2458/00

Abstract: Sterilization indicators that include a neutralizer, such indicators useful for testing the effectiveness of a sterilization procedure by measuring the activity of an active enzyme whose activity is correlated with the survival of microorganisms.

Abstract translation: 包括中和剂的消毒指示剂，这些指标可用于通过测量活性与微生物存活相关的活性酶的活性来测试灭菌程序的有效性。

公开(公告)号：US08623935B2

公开(公告)日：2014-01-07

申请号：US12811184

申请日：2008-12-31

Applicant: Terry R. Hobbs ,  Robert A. Asmus

Inventor： Terry R. Hobbs ,  Robert A. Asmus

IPC: C08K5/00 ,  C08K5/05

CPC classification number: A01N25/02 ,  A01N25/10 ,  A01N47/44 ,  A01N2300/00

Abstract: Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a hydrophobic polymer soluble in the lower alcohol; an emollient ester such as diesters of bibasic acids and triesters of citric acid; and an optional fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

Abstract translation: 提供了抗微生物组合物，其包括含有较低C 2 -C 5醇和水的水醇溶剂体系; 阳离子抗菌剂，如葡萄糖酸洗必太; 可溶于低级醇的疏水性聚合物; 一种软化酯如二元酸二酯和柠檬酸三酯; 和含有至少一个游离羟基的任选的脂肪组分，例如C 12 -C 21脂肪醇，C 12 -C 21脂肪酸酯，C 12 -C 21脂肪醚，C 12 -C 21脂肪酰胺及其组合。 本文所述的组合物显示出改进的抗微生物效能和改善的美容优雅。

公开(公告)号：US20120164056A1

公开(公告)日：2012-06-28

申请号：US13381219

申请日：2010-06-28

Applicant: Louis C. Haddad ,  William E. Foltz ,  Greggory S. Bennett ,  Robert A. Asmus

Inventor： Louis C. Haddad ,  William E. Foltz ,  Greggory S. Bennett ,  Robert A. Asmus

IPC: A61L2/20 ,  C09K3/00 ,  C01B21/36

CPC classification number: A61L2/20 ,  A61L2/202 ,  A61L2/206 ,  A61L2/208 ,  A61L2/24 ,  A61L2202/11 ,  A61L2202/122 ,  A61L2202/14 ,  A61L2202/24 ,  C01B11/022 ,  C01B21/20 ,  C01B21/36

Abstract: The disclosure provides processes and systems for sterilizing an object using a sterilant gas. In some embodiments, the sterilant gas is produced by the thermal decomposition of a salt. Compositions to generate sterilant gasses are also disclosed.

Abstract translation: 本公开提供了使用灭菌气体对物体进行灭菌的过程和系统。 在一些实施方案中，消毒剂气体是通过盐的热分解产生的。 还公开了产生灭菌气体的组合物。

公开(公告)号：US20110110869A1

公开(公告)日：2011-05-12

申请号：US13006583

申请日：2011-01-14

Applicant: Matthew T. Scholz ,  Robert A. Asmus ,  Jill R. Charpentier

Inventor： Matthew T. Scholz ,  Robert A. Asmus ,  Jill R. Charpentier

IPC: A61K9/12

CPC classification number: A61K8/34 ,  A61K8/342 ,  A61K8/37 ,  A61K8/39 ,  A61K8/416 ,  A61K8/604 ,  A61K8/86 ,  A61Q17/005 ,  A61Q19/00 ,  Y10S514/846 ,  Y10S514/873 ,  Y10S514/944 ,  Y10S514/945 ,  Y10S514/946 ,  Y10S514/975

Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.

Abstract translation: 公开了包含低级醇和水的组合物，其重量比为约35:65至100:0，至少0.5重量％至8.0重量％的包含至少两种乳化剂的增稠剂体系，每种乳化剂存在于至少0.05 重量％，并且其中每种乳化剂由至少一个疏水基团和至少一个亲水基团组成。 组合物可用作术前洗刷替代物，洗剂或其他手制剂。

公开(公告)号：US20100331411A1

公开(公告)日：2010-12-30

申请号：US12878786

申请日：2010-09-09

Applicant: Robert A. Asmus

Inventor： Robert A. Asmus

IPC: A01N31/02 ,  A01N47/44 ,  A01N31/08 ,  A01N31/16 ,  A01N37/36 ,  A01P1/00 ,  B67D7/76

CPC classification number: A61K8/894 ,  A61K8/34 ,  A61K8/731 ,  A61K8/86 ,  A61Q17/005 ,  C11D1/82 ,  C11D3/0094 ,  C11D3/2006 ,  C11D3/201 ,  C11D3/225 ,  C11D3/3707 ,  C11D3/48

Abstract: A composition, systems for dispensing the composition and methods for the use of the composition are described. The composition comprises: (A) Monohydric alcohol in an amount sufficient to provide antimicrobial activity; (B) Surfactant comprising a dimethicone surfactant; and (C) Builder, the builder in an amount sufficient to provide stability or to improve the stability of a foam formed from the composition.

公开(公告)号：US06458341B1

公开(公告)日：2002-10-01

申请号：US09089872

申请日：1998-06-04

Applicant: Sharon M. Rozzi ,  Robert A. Asmus ,  Brian R. Morrison

Inventor： Sharon M. Rozzi ,  Robert A. Asmus ,  Brian R. Morrison

IPC: A61K722

CPC classification number: A61K8/345 ,  A61K8/43 ,  A61Q11/00 ,  Y10T428/2938

Abstract: Devices, coating compositions and methods for making such compositions are provided, wherein the coatings deliver chlorhexidine gluconate from a stable non-aqueous system.

Abstract translation: 提供了用于制备这种组合物的装置，涂料组合物和方法，其中所述涂层从稳定的非水系统递送氯己定葡萄糖酸氯己定。

公开(公告)号：US09278155B2

公开(公告)日：2016-03-08

申请号：US10456811

申请日：2003-06-05

Applicant: Robert A. Asmus ,  Beatrice C. Etzold ,  Joy A. Packard

Inventor： Robert A. Asmus ,  Beatrice C. Etzold ,  Joy A. Packard

IPC: A61F13/02 ,  A61L15/58 ,  C09J133/24 ,  C08K5/053 ,  C08L1/00 ,  C08L5/00

CPC classification number: A61L15/58 ,  C08K5/053 ,  C08L1/00 ,  C08L5/00 ,  C08L2666/26 ,  C09J133/24 ,  C08L39/04

Abstract: A hydrophilic, pressure-sensitive adhesive composition comprising crosslinked poly(N-vinyl lactam), a swelling agent, and a modifying polymer in an amount sufficient to form a cohesive pressure-sensitive adhesive composition is provided. The composition is useful as a medical secural of percutaneous devices. The composition is also useful as a drug delivery device to deliver antimicrobial agents, pharmaceuticals or other active ingredients to or through skin. A method of preparation of the composition is also disclosed.

Abstract translation: 提供一种亲水性压敏粘合剂组合物，其包含交联的聚（N-乙烯基内酰胺），溶胀剂和改进聚合物，其量足以形成内聚压敏粘合剂组合物。 该组合物可用作经皮装置的医学证实。 该组合物还可用作药物递送装置，以将抗微生物剂，药物或其它活性成分递送至皮肤或通过皮肤。 还公开了组合物的制备方法。

公开(公告)号：US08338491B2

公开(公告)日：2012-12-25

申请号：US12445376

申请日：2007-10-25

Applicant: Robert A. Asmus ,  Terry R. Hobbs

Inventor： Robert A. Asmus ,  Terry R. Hobbs

IPC: A01N33/18 ,  A61K6/00

CPC classification number: A61K31/155 ,  A01N31/02 ,  A01N33/12 ,  A01N47/44 ,  A01N25/02 ,  A01N37/04 ,  A01N37/36 ,  A01N2300/00

Abstract: Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water; a cationic antimicrobial agent such as chlorhexidine gluconate; a fatty component containing at least one free hydroxyl group, such as a C12-C21 fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C21 fatty amide, and combinations thereof; and optionally an emollient ester such as diesters of bibasic acids and triesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.

Abstract translation: 提供了抗微生物组合物，其包括含有较低C 2 -C 5醇和水的水醇溶剂体系; 阳离子抗菌剂，如葡萄糖酸洗必太; 含有至少一个游离羟基的脂肪成分，如C12-C21脂肪醇，C12-C21脂肪酸酯，C12-C21脂肪醚，C12-C21脂肪酰胺及其组合; 和任选的软化酯，例如二元酸的二酯和柠檬酸的三酯。 本文所述的组合物显示出改进的抗微生物效能和改善的美容优雅。

公开(公告)号：US20120184929A1

公开(公告)日：2012-07-19

申请号：US13350580

申请日：2012-01-13

Applicant: Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

Inventor： Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

IPC: A61M35/00

CPC classification number: A61M35/006

Abstract: Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.

Abstract translation: 公开了皮肤防腐剂组合物分配器和使用方法。 皮肤消毒组合物分配器可以包括具有一个或多个壁的容器，所述壁在正常环氧乙烷灭菌过程中基本上不渗透环氧乙烷气体。 在一些实施例中，容器可以包括没有金属箔阻挡层的柔性壁。 除了用于分配容器内的皮肤消毒组合物的一个或多个开口之外，容器还可以包括一个或多个通气口。 分配器可以包括具有亲水性泡沫的涂布器。

公开(公告)号：US08105306B2

公开(公告)日：2012-01-31

申请号：US10821078

申请日：2004-04-08

Applicant: Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

Inventor： Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

IPC: A61B19/00 ,  A61L2/18 ,  A61L2/20

CPC classification number: A61L2/0088 ,  A61M35/003 ,  A61M35/006

Abstract: Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.