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公开(公告)号:US20090081257A1
公开(公告)日:2009-03-26
申请号:US10591203
申请日:2005-02-28
申请人: Robert J. Maier , John S. Gunn
发明人: Robert J. Maier , John S. Gunn
IPC分类号: A61K39/108 , C12N1/21 , A61K39/02 , A61P37/04 , A61P31/04 , A61K35/74 , A61K39/112
CPC分类号: C12N9/0067 , A61K39/0258 , A61K39/0275 , A61K39/105 , A61K2039/522 , C12Y112/01002 , Y02A50/47 , Y02A50/474 , Y02A50/482 , Y02A50/484 , Y10S435/879
摘要: The present disclosure describes pathogenic bacteria that have been modified to be deficient in NiFe hydrogenase activity; compositions comprising such modified bacteria, and the use of such bacteria to protect animals from pathogenic enteric bacterial infections.
摘要翻译: 本公开描述已经被修饰为缺乏NiFe氢化酶活性的病原菌; 包含这种修饰细菌的组合物,以及这种细菌用于保护动物免受致病性肠道细菌感染的用途。
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公开(公告)号:US5308616A
公开(公告)日:1994-05-03
申请号:US563171
申请日:1990-08-06
申请人: Robert J. Maier
发明人: Robert J. Maier
CPC分类号: C12R1/01 , C05F11/08 , Y10S435/822
摘要: The present invention relates to mutant strains of Bradyrhizobium japonicum that are characterized in an increased nitrogen fixation rate and an altered molybdenum metabolism. The mutant strains require higher levels of molybdate than wild-type Bradyrhizobium japonicum for expression of nitrate reductase activity. In addition, the mutant strains express free-living nitrogenase activity in medium treated to remove molybdate, where the wild-type require molybdate supplementation.
摘要翻译: 本发明涉及具有增加的固氮率和改变的钼代谢的特征在于日本的Bradyrhizobium japonicum的突变菌株。 突变菌株比野生型Bradyrhizobium japonicum需要更高水平的钼酸盐,用于表达硝酸还原酶活性。 此外,突变菌株在处理的培养基中表达自由活性的氮酶活性以除去钼酸盐,其中野生型需要补充钼酸盐。
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公开(公告)号:US07919081B2
公开(公告)日:2011-04-05
申请号:US10591203
申请日:2005-02-28
申请人: Robert J. Maier , John S. Gunn
发明人: Robert J. Maier , John S. Gunn
CPC分类号: C12N9/0067 , A61K39/0258 , A61K39/0275 , A61K39/105 , A61K2039/522 , C12Y112/01002 , Y02A50/47 , Y02A50/474 , Y02A50/482 , Y02A50/484 , Y10S435/879
摘要: The present disclosure describes pathogenic bacteria that have been modified to be deficient in NiFe hydrogenase activity; compositions comprising such modified bacteria, and the use of such bacteria to protect animals from pathogenic enteric bacterial infections.
摘要翻译: 本公开描述已经被修饰为缺乏NiFe氢化酶活性的病原菌; 包含这种修饰细菌的组合物,以及这种细菌用于保护动物免受致病性肠道细菌感染的用途。
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公开(公告)号:USD364721S
公开(公告)日:1995-12-05
申请号:US32444
申请日:1994-12-19
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