METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION
    3.
    发明申请
    METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION 审中-公开
    改善细胞功能的方法和组合物

    公开(公告)号:US20100247679A1

    公开(公告)日:2010-09-30

    申请号:US12754160

    申请日:2010-04-05

    申请人: Ronan Power

    发明人: Ronan Power

    IPC分类号: A61K33/04 A61P25/16 A61P25/28

    摘要: The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).

    摘要翻译: 本发明涉及用于改变细胞功能的组合物和方法。 特别地,本发明提供了包含硒(例如,SEL-PLEX)的组合物及其使用方法(例如,作为治疗和/或预防性治疗)。 另外,本发明证明当施用于受试者时,具体形式的硒(例如,SEL-PLEX)具有改变(例如,降低)各种组织中的基因表达的能力(例如,与未施用的受试者的表达相比较) 硒)。

    Methods for separating soluble selenoglycoproteins
    6.
    发明授权
    Methods for separating soluble selenoglycoproteins 有权
    分离可溶性硒代糖蛋白的方法

    公开(公告)号:US08263752B2

    公开(公告)日:2012-09-11

    申请号:US13051646

    申请日:2011-03-18

    IPC分类号: C07K1/30 C07K1/36

    摘要: The invention relates to soluble selenium compositions and methods of production, separation and purification thereof. In particular the present invention provides methods of preparing water soluble selenoglycoproteins (e.g., via extracting selenoglycoproteins from selenium enriched yeast), methods of supplementing a selenium deficient composition via admixing water soluble selenoglycoproteins with the selenium deficient composition, compositions comprising the water soluble selenoglycoproteins and methods of administering the same.

    摘要翻译: 本发明涉及可溶性硒组合物及其生产,分离和纯化方法。 特别地,本发明提供了制备水溶性硒代糖蛋白的方法(例如,通过从富硒酵母提取硒代糖蛋白),通过将水溶性硒代糖蛋白与缺硒组合物混合来补充硒缺乏组合物的方法,包含水溶性硒代糖蛋白的组合物和方法 的管理。

    Compositions and methods for establishing and/or maintaining pregnancy
    8.
    发明授权
    Compositions and methods for establishing and/or maintaining pregnancy 有权
    用于建立和/或维持怀孕的组成和方法

    公开(公告)号:US08846111B2

    公开(公告)日:2014-09-30

    申请号:US12122331

    申请日:2008-05-16

    IPC分类号: A61K33/04 A61K36/06

    摘要: Compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment) are provided. For example, compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same are provided for treating and/or preventing one or more conditions (e.g., problems) disorders, and/or diseases related to establishing and/or maintaining a pregnancy. Compositions and methods of the invention find use in, among other things, research and clinical (e.g., preventative and therapeutic) applications.

    摘要翻译: 提供了包含硒(例如有机硒(例如,硒化酵母(例如,SEL-PLEX))的组合物)及其使用方法(例如,作为治疗和/或预防性治疗)。 例如,提供包含硒(例如有机硒(例如,硒化酵母(例如,SEL-PLEX))的组合物)及其使用方法用于治疗和/或预防一种或多种病症(例如问题)障碍, 和/或与建立和/或维持怀孕相关的疾病。 本发明的组合物和方法尤其可用于研究和临床(例如预防和治疗)应用。

    METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION
    9.
    发明申请
    METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION 审中-公开
    改善细胞功能的方法和组合物

    公开(公告)号:US20110008466A1

    公开(公告)日:2011-01-13

    申请号:US12833782

    申请日:2010-07-09

    IPC分类号: A61K33/04 A61P25/28 A61P25/16

    CPC分类号: A61K33/04

    摘要: The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).

    摘要翻译: 本发明涉及用于改变细胞功能的组合物和方法。 特别地,本发明提供了包含硒(例如,SEL-PLEX)的组合物及其使用方法(例如,作为治疗和/或预防性治疗)。 另外,本发明证明当施用于受试者时,具体形式的硒(例如,SEL-PLEX)具有改变(例如,降低)各种组织中的基因表达的能力(例如,与未施用的受试者的表达相比较) 硒)。

    Methods and compositions for altering cell function
    10.
    发明申请
    Methods and compositions for altering cell function 审中-公开
    用于改变细胞功能的方法和组合物

    公开(公告)号:US20080107755A1

    公开(公告)日:2008-05-08

    申请号:US11789275

    申请日:2007-04-24

    IPC分类号: A61K33/04 A61P25/16 A61P25/28

    CPC分类号: A61K33/04

    摘要: The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).

    摘要翻译: 本发明涉及用于改变细胞功能的组合物和方法。 特别地,本发明提供了包含硒(例如,SEL-PLEX)的组合物及其使用方法(例如,作为治疗和/或预防性治疗)。 另外,本发明证明当施用于受试者时,具体形式的硒(例如,SEL-PLEX)具有改变(例如,降低)各种组织中的基因表达的能力(例如,与未施用的受试者的表达相比较) 硒)。