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    IMAGE ANALYZING DEVICE AND IMAGE ANALYZING METHOD
    1.
    发明申请
    IMAGE ANALYZING DEVICE AND IMAGE ANALYZING METHOD 有权

    公开(公告)号：US20220292671A1

    公开(公告)日：2022-09-15

    申请号：US17624886

    申请日：2019-07-10

    Applicant: CYBERNET SYSTEMS CO., LTD. ,  SHOWA UNIVERSITY

    Inventor： Masashi Misawa ,  Yuichi Mori ,  Shin-ei Kudo ,  Takashi Wakisaka ,  Hideo Kahara

    IPC: G06T7/00 ,  G16H30/40 ,  G16H50/20

    Abstract: An object to allow an automatic discrimination between a super enlarged image and a non-enlarged image in a computer diagnosis assistance system that analyzes a state of an epithelium using an image analysis. An image analyzing device according to this disclosure is the image analyzing device to be connected to an endoscope, and includes a target image determination unit that obtains an image from the endoscope and determines whether or not the image is a target image using a halation region included in the image, and an image analyzing unit that analyzes a state of an epithelium, captured by the endoscope, using the target image when the image is the target image.

    DETECTION METHOD AND DETECTION DEVICE OF CIRCULATING TUMOR CELL
    3.
    发明申请
    DETECTION METHOD AND DETECTION DEVICE OF CIRCULATING TUMOR CELL 审中-公开

    公开(公告)号：US20200284796A1

    公开(公告)日：2020-09-10

    申请号：US16807567

    申请日：2020-03-03

    Applicant: Showa University

    Inventor： Michio NAOE ,  Yoshio OGAWA ,  Hikaru ISHII

    IPC: G01N33/574 ,  B01L3/00 ,  G01N15/14

    Abstract: A detection method of detecting CTCs as target cells contained in a test sample, the method includes a concentration step of concentrating the target cells contained in the test sample, a labeling step of labeling the target cells and other components by bringing the concentrated test sample into contact with first labeling antibodies in which antibodies specifically binding to antigens, which exclude antigens expressing in epithelial cells and specifically express in the target cells, are labeled by a first labeling substance, and into contact with second labeling antibodies in which antibodies binding to antigens expressing in the other components excluding the target cells are labeled by a second labeling substance, and a detection step of detecting, from the test sample, cells that are labeled by the first labeling antibodies and are not labeled by the second labeling antibodies as the target cells.

    DENTAL ULTRASONIC CLEANING DEVICE AND METHOD FOR CLEANING TEETH OR DENTURES BY USING ULTRASONIC WAVES
    6.
    发明申请
    DENTAL ULTRASONIC CLEANING DEVICE AND METHOD FOR CLEANING TEETH OR DENTURES BY USING ULTRASONIC WAVES 有权
    牙科超声清洁装置及使用超声波清洗牙齿或牙齿的方法

    公开(公告)号：US20150111169A1

    公开(公告)日：2015-04-23

    申请号：US14404459

    申请日：2013-04-26

    Applicant: SHOWA UNIVERSITY

    Inventor： Matsuo Yamamoto ,  Takashi Takiguchi ,  Masanori Sato ,  Katsuyuki Inagaki ,  Kazumasa Kubota ,  Hideo Kozaka ,  Toshiaki Miyamoto

    IPC: A61C17/20 ,  A61C17/02

    CPC classification number: A61C17/20 ,  A61C17/0202 ,  A61C17/0208

    Abstract: Provided is a dental ultrasonic cleaning device that efficiently cleans teeth or dentures in an oral cavity using ultrasonic waves. A dental ultrasonic cleaning device 1 emits ultrasonic waves through a cleaning-liquid (W1) to the surface of a cleaning-target 26, ultrasonically cleaning it. An ultrasonic born 24 propagates ultrasonic waves being generated by an ultrasonic-wave transducer 23 and emits them from the vibratory surface 25 provided at the tip-end of the horn 24. A liquid-reserving part 27 is provided, surrounding the vibratory surface 25 of the ultrasonic horn 24, which temporarily reserves the cleaning-liquid (W1) between the vibratory surface 25 and the cleaning-target 26. A cap-member 33 is provided at a certain interval opposite the liquid-reserving part 27. A cleaning-liquid discharge-tube inlet 35 is connected to a vacuum tube 36 within the cap-member 33, allowing the cleaning-liquid W1 used during the ultrasonic cleaning to be vacuumed from the oral cavity, into the cap-member 33, and then discharged through the vacuum tube 36.

    Abstract translation: 提供一种使用超声波有效地清洁口腔中的牙齿或假牙的牙科超声波清洗装置。 牙科用超声波清洗装置1通过清洗液（W1）向清洁对象物26的表面发射超声波，进行超声波清洗。 超声波出生的24传播由超声波换能器23产生的超声波，并从设置在喇叭24的前端的振动面25发射出来。设置液体保留部27，围绕振动面25的振动面25 超声波喇叭24临时保存振动表面25和清洁对象26之间的清洁液（W1）。盖部件33以与液体储存部分27相对的一定间隔设置。清洁液体 排出管入口35连接到盖构件33内的真空管36，使得在超声波清洗期间使用的清洁液W1从口腔抽吸到盖构件33中，然后通过 真空管36。

    APPARATUS AND METHOD FOR EVALUATING DIABETIC PERIPHERAL NEUROPATHY
    10.
    发明申请
    APPARATUS AND METHOD FOR EVALUATING DIABETIC PERIPHERAL NEUROPATHY 审中-公开
    用于评估糖尿病性外周神经病变的装置和方法

    公开(公告)号：US20150182158A1

    公开(公告)日：2015-07-02

    申请号：US14411470

    申请日：2012-09-18

    Applicant: Noriyo TAKAHASHI ,  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY ,  SHOWA UNIVERSITY ,  ASUKA ELECTRIC CO., LTD.

    Inventor： Shuichi Ino ,  Mitsuru Sato ,  Noriyo Takahashi ,  Shinichi Yoshimura

    IPC: A61B5/00

    CPC classification number: A61B5/4076 ,  A61B5/0051 ,  A61B5/4005 ,  A61B5/4029 ,  A61B5/4827 ,  A61B5/6829 ,  A61B5/742 ,  F04C2270/041

    Abstract: [Problem]To provide an apparatus for measuring a sensory threshold at the time of application of a moving stimulus to a sole simply with high reproducibility and evaluating peripheral neuropathy originating in diabetes.[Solution]Provided are a foot pedestal 2, a probe 4 for applying a moving stimulus to a sole, and a probe driving structure 3, disposed on a base 1, for operating the probe 4 to separately move in directions intersecting at right angles along the sole. Also provided are an input switch 5 to be operated by a subject recognizing a moving stimulus, a drive controller 51 for controlling drive condition of the probe driving structure 3, and a main controller B for evaluating a measured sensory threshold. The main controller B preliminarily stores reference data of known sensory thresholds obtained by applying a moving stimulus to a sole of patients, and age correction factors calculated from standard values of sensory thresholds based on different ages of patients. The drive controller 51 controls drive condition of the probe driving structure 3 by using the reference data and the age correction factors to conduct a primary stimulus applying condition. Further, a secondary stimulus applying condition, and a tertiary stimulus applying condition are sequentially conducted to measure a sensory threshold.

    Abstract translation: 本发明提供一种用于在将运动刺激应用于鞋底的情况下测量感觉阈值的装置，简单地具有高再现性并评估源于糖尿病的周围神经病变。 [解决方案]设置有脚踏座2，用于向鞋底施加移动刺激的探针4和设置在基座1上的探针驱动结构3，用于操作探针4以沿直角相交的方向分开移动 唯一的。 还提供了由被识别移动刺激的被摄体操作的输入开关5，用于控制探针驱动结构3的驱动条件的驱动控制器51和用于评估测量的感觉阈值的主控制器B. 主控制器B预先存储通过将运动刺激应用于患者唯一而获得的已知感觉阈值的参考数据，以及基于患者不同年龄的感觉阈值的标准值计算的年龄校正因子。 驱动控制器51通过使用参考数据和年龄校正因子来控制探针驱动结构3的驱动条件以进行主刺激施加条件。 此外，依次进行二次刺激施加条件和三次刺激施加条件以测量感觉阈值。

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