-
1.发明申请OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS 审中-公开氧合物衍生物及其在治疗神经疾病中的应用公开(公告)号：US20150018338A1
公开(公告)日：2015-01-15
申请号：US14324883
申请日：2014-07-07
Applicant: Sangamesh BADIGER , Murali CHEBROLU , Mathias FREDERIKSEN , Philipp HOLZER , Konstanze HURTH , Rainer Martin LEUOEND , Rainer MACHAUER , Henrik MOEBITZ , Ulf NEUMANN , Rita RAMOS , Henrich RUEEGER , Michael SCHAEFER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
Inventor： Sangamesh BADIGER , Murali CHEBROLU , Mathias FREDERIKSEN , Philipp HOLZER , Konstanze HURTH , Rainer Martin LEUOEND , Rainer MACHAUER , Henrik MOEBITZ , Ulf NEUMANN , Rita RAMOS , Henrich RUEEGER , Michael SCHAEFER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
IPC: C07D487/04 , A61K31/5377 , C07D413/14 , C07D471/04 , C07D417/12 , A61K31/553 , C07D413/12
CPC classification number: C07D487/04 , A61K31/5377 , A61K31/553 , A61K45/06 , C07D265/30 , C07D267/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.
Abstract translation: 本发明涉及下式的新型杂环化合物，其中所有变量如本说明书中所定义，以游离形式或盐形式，其制备，其医疗用途和包含它们的药物。
-
2.发明申请Novel Heterocyclic Derivatives and Their Use in the Treatment of Neurological Disorders 有权新型杂环衍生物及其在神经障碍治疗中的应用公开(公告)号：US20140107118A1
公开(公告)日：2014-04-17
申请号：US14136855
申请日：2013-12-20
Applicant: Sangamesh BADIGER , Murali CHEBROLU , Konstanze HURTH , Sebastien JACQUIER , Rainer Martin LUEOEND , Rainer MACHAUER , Heinrich RUEEGER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
Inventor： Sangamesh BADIGER , Murali CHEBROLU , Konstanze HURTH , Sebastien JACQUIER , Rainer Martin LUEOEND , Rainer MACHAUER , Heinrich RUEEGER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
IPC: C07D413/14 , C07D487/04 , C07D471/04 , A61K31/5377
CPC classification number: C07D413/14 , A61K31/5377 , C07B59/002 , C07B2200/05 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.
Abstract translation: 本发明涉及下式的新型杂环化合物，其中所有变量如本说明书中所定义，其药物组合物，其组合及其作为药物的用途，特别是用于通过BACE-抑制剂的抑制治疗阿尔茨海默病或糖尿病， 1或BACE-2。
-
![Diaza-spiro[5.5]undecanes](/abs-image/US/2012/04/26/US20120101110A1/abs.jpg.150x150.jpg)
公开(公告)号：US20120101110A1
公开(公告)日：2012-04-26
申请号：US13275837
申请日：2011-10-18
Applicant: Sangamesh BADIGER , Dirk BEHNKE , Claudia BETSCHART , Simona COTESTA , Samuel HINTERMANN , Silvio OFNER , Chetan PANDIT , Bernard Lucien ROY
Inventor： Sangamesh BADIGER , Dirk BEHNKE , Claudia BETSCHART , Simona COTESTA , Samuel HINTERMANN , Silvio OFNER , Chetan PANDIT , Bernard Lucien ROY
IPC: A61K31/506 , A61K31/444 , A61K31/497 , A61P25/00 , A61P25/18 , A61P25/28 , A61K31/438 , C07D471/10 , A61P25/30
CPC classification number: C07D471/10 , A61K31/444 , A61K31/506 , A61K45/06 , C07D519/00
Abstract: The invention relates to compound of the formula I in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
Abstract translation: 本发明涉及式I化合物，其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备，用作药物和包含它的药物。
-
公开(公告)号：US08742106B2
公开(公告)日：2014-06-03
申请号：US13517115
申请日：2010-12-20
Applicant: Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Murali Chebrolu , Simona Cotesta , Samuel Hintermann , Arndt Meyer , Chetan Pandit
Inventor： Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Murali Chebrolu , Simona Cotesta , Samuel Hintermann , Arndt Meyer , Chetan Pandit
IPC: C07D471/04 , C07D498/04 , C07D519/00
CPC classification number: C07D471/04 , C07D498/04 , C07D519/00
Abstract: The invention relates to compound of the formula (I′) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
Abstract translation: 本发明涉及式（I'）的化合物，其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备，用作药物和包含它的药物。
-
公开(公告)号：US07521465B2
公开(公告)日：2009-04-21
申请号：US11096718
申请日：2005-03-31
Applicant: Bishwajit Nag , Abhijeet Nag , Debendranath Dey , Shiv Kumar Agarwal , Partha Neogi , Gaddam Om Reddy , Sangamesh Badiger , Gajendra Singh , Surendra Kumar Pandey , Santhanagopalan Chithra
Inventor： Bishwajit Nag , Abhijeet Nag , Debendranath Dey , Shiv Kumar Agarwal , Partha Neogi , Gaddam Om Reddy , Sangamesh Badiger , Gajendra Singh , Surendra Kumar Pandey , Santhanagopalan Chithra
IPC: A61K31/426 , A61K31/421
CPC classification number: C07D277/20 , A61K31/4164 , A61K31/421 , A61K31/426 , C07D277/34 , C07D277/36
Abstract: Novel diphenyl ether derivatives are provided that exhibit activity useful for reducing glucose, cholesterol, and/or triglyceride levels in plasma, and for treatment of obesity, inflammation, immunological diseases, autoimmune diseases, diabetes and disorders associated with insulin resistance.
Abstract translation: 提供新的二苯醚衍生物，其显示可用于降低血浆中的葡萄糖，胆固醇和/或甘油三酯水平的活性，以及用于治疗肥胖，炎症，免疫疾病，自身免疫性疾病，糖尿病和与胰岛素抵抗相关的疾病。
-
Patent Agency Ranking
公开(公告)号：US20050288341A1
公开(公告)日：2005-12-29
申请号：US11096718
申请日：2005-03-31
Applicant: Bishwajit Nag , Abhijeet Nag , Debendranath Dey , Shiv Agarwal , Partha Neogi , Gaddam Reddy , Sangamesh Badiger , Gajendra Singh , Surendra Pandey , Santhanagopalan Chithra
Inventor： Bishwajit Nag , Abhijeet Nag , Debendranath Dey , Shiv Agarwal , Partha Neogi , Gaddam Reddy , Sangamesh Badiger , Gajendra Singh , Surendra Pandey , Santhanagopalan Chithra
IPC: A61K31/4164 , A61K31/421 , A61K31/426
CPC classification number: C07D277/20 , A61K31/4164 , A61K31/421 , A61K31/426 , C07D277/34 , C07D277/36
Abstract: Novel diphenyl ether derivatives are provided that exhibit activity useful for reducing glucose, cholesterol, and/or triglyceride levels in plasma, and for treatment of obesity, inflammation, immunological diseases, autoimmune diseases, diabetes and disorders associated with insulin resistance.
Abstract translation: 提供新的二苯醚衍生物，其显示可用于降低血浆中的葡萄糖，胆固醇和/或甘油三酯水平的活性，以及用于治疗肥胖，炎症，免疫疾病，自身免疫性疾病，糖尿病和与胰岛素抵抗相关的疾病。
-
7.发明申请Novel Heterocyclic Derivatives and Their Use in the Treatment of Neurological Disorders 审中-公开新型杂环衍生物及其在神经障碍治疗中的应用公开(公告)号：US20150203481A1
公开(公告)日：2015-07-23
申请号：US14482662
申请日：2014-09-10
Applicant: Sangamesh BADIGER , Murali CHEBROLU , Konstanze HURTH , Sebastien JACQUIER , Rainer Martin LUEOEND , Rainer MACHAUER , Heinrich RUEEGER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
Inventor： Sangamesh BADIGER , Murali CHEBROLU , Konstanze HURTH , Sebastien JACQUIER , Rainer Martin LUEOEND , Rainer MACHAUER , Heinrich RUEEGER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
IPC: C07D413/14 , C07D487/04 , C07D471/04 , A61K31/5377
CPC classification number: C07D413/14 , A61K31/5377 , C07B59/002 , C07B2200/05 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.
Abstract translation: 本发明涉及下式的新型杂环化合物，其中所有变量如本说明书中所定义，其药物组合物，其组合及其作为药物的用途，特别是用于通过BACE-抑制剂的抑制治疗阿尔茨海默病或糖尿病， 1或BACE-2。
-
8.发明申请OXAZINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS 审中-公开氧合物衍生物及其在治疗神经疾病中的应用公开(公告)号：US20120302558A1
公开(公告)日：2012-11-29
申请号：US13255036
申请日：2011-07-13
Applicant: Sangamesh Badiger , Murali Chebrolu , Mathias Frederiksen , Philipp Holzer , Konstanze Hurth , Rainer Martin Lueoend , Rainer Machauer , Henrik Moebitz , Ulf Neumann , Rita Ramos , Heinrich Rueeger , Michael Schaefer , Marina Tintelnot-Blomley , Siem Jacob Veenstra , Markus Voegtle , Lei Li , Hui Liu , Xin Xiong
Inventor： Sangamesh Badiger , Murali Chebrolu , Mathias Frederiksen , Philipp Holzer , Konstanze Hurth , Rainer Martin Lueoend , Rainer Machauer , Henrik Moebitz , Ulf Neumann , Rita Ramos , Heinrich Rueeger , Michael Schaefer , Marina Tintelnot-Blomley , Siem Jacob Veenstra , Markus Voegtle , Lei Li , Hui Liu , Xin Xiong
IPC: A61K31/5377 , A61P25/28 , C07D413/12
CPC classification number: C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.
Abstract translation: 本发明涉及下式的新型杂环化合物，其中所有变量如本说明书中所定义，以游离形式或盐形式，其制备，其医疗用途和包含它们的药物。
-
![DIAZA-SPIRO[5.5]UNDECANES](/abs-image/US/2012/10/18/US20120264748A1/abs.jpg.150x150.jpg)
公开(公告)号：US20120264748A1
公开(公告)日：2012-10-18
申请号：US13517111
申请日：2010-12-20
Applicant: Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Simona Cotesta , Jürgen Hans-Hermann Hinrichs , Silvio Ofner , Chetan Pandit , Jürgen Wagner
Inventor： Sangamesh Badiger , Dirk Behnke , Claudia Betschart , Vinod Chaudhari , Simona Cotesta , Jürgen Hans-Hermann Hinrichs , Silvio Ofner , Chetan Pandit , Jürgen Wagner
IPC: C07D471/10 , A61K31/438 , A61K31/506 , A61K31/5377 , A61P3/00 , A61K31/5025 , A61P25/00 , A61P25/30 , A61P25/28 , A61K31/502 , A61K31/538
CPC classification number: C07D471/10
Abstract: The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
Abstract translation: 本发明涉及式（I）化合物，其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备，用作药物和包含它的药物。
-
10.发明申请公开(公告)号：US20110021520A1
公开(公告)日：2011-01-27
申请号：US12842360
申请日：2010-07-23
Applicant: Sangamesh BADIGER , Murali CHEBROLU , Mathias FREDERIKSEN , Philipp HOLZER , Konstanze HURTH , Rainer Martin LUEOEND , Rainer MACHAUER , Henrik MOEBITZ , Ulf NEUMANN , Rita RAMOS , Heinrich RUEEGER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
Inventor： Sangamesh BADIGER , Murali CHEBROLU , Mathias FREDERIKSEN , Philipp HOLZER , Konstanze HURTH , Rainer Martin LUEOEND , Rainer MACHAUER , Henrik MOEBITZ , Ulf NEUMANN , Rita RAMOS , Heinrich RUEEGER , Marina TINTELNOT-BLOMLEY , Siem Jacob VEENSTRA , Markus VOEGTLE
IPC: A61K31/5377 , C07D413/12 , C07D419/12 , C07D265/30 , A61K31/5375 , A61P25/28
CPC classification number: C07D487/04 , A61K31/5377 , A61K31/553 , A61K45/06 , C07D265/30 , C07D267/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their medical use and to medicaments comprising them.
Abstract translation: 本发明涉及下式的新型杂环化合物，其中所有变量如本说明书中所定义，以游离形式或盐形式，其制备，其医疗用途和包含它们的药物。
-
-
-
-
-
-
-
-
-
Search Results
18
records
(took 0.027 seconds)
