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公开(公告)号：US20110256114A1
公开(公告)日：2011-10-20
申请号：US13167414
申请日：2011-06-23
CPC分类号： C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要： A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
摘要翻译： 一种多肽，其包含由序列表的SEQ ID NO：5所示的氨基酸序列组成的多肽或由序列中一至数个氨基酸残基的缺失，添加，插入或取代的氨基酸序列组成的多肽， 能够构成HLA-A24限制性MAGE-A4143-151特异性T细胞受体的多肽以及由序列表的SEQ ID NO：2所示的氨基酸序列组成的多肽。
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公开(公告)号：US08383401B2
公开(公告)日：2013-02-26
申请号：US13167414
申请日：2011-06-23
CPC分类号： C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要： A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
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公开(公告)号：US20090068209A1
公开(公告)日：2009-03-12
申请号：US12113822
申请日：2008-05-01
CPC分类号： C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要： The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译： 本发明涉及具有诱导识别抗原的T淋巴细胞的活性的T淋巴细胞和使用T淋巴细胞的技术。
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公开(公告)号：US08168191B2
公开(公告)日：2012-05-01
申请号：US12113822
申请日：2008-05-01
CPC分类号： C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要： The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译： 本发明涉及具有诱导T淋巴细胞识别抗原的活性的T淋巴细胞和使用T淋巴细胞的技术。
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公开(公告)号：US20120093708A1
公开(公告)日：2012-04-19
申请号：US13378389
申请日：2010-07-22
摘要： Provided is an extracting and separating device which includes: an ash reactor 12 for preparing a solution having a temperature of about 60° C. by using incineration ash containing sodium, potassium, and chlorine; a cooling crystallizer 16 for reducing the temperature of the solution to 30° C. to produce and separate potassium chloride; an absorption tower 11 for reacting the solution with carbon dioxide-containing gas to produce and separate sodium hydrogen carbonate; and a circulation path 13 for returning to the ash reactor 12 a liquid obtained after the production and separation of the potassium chloride in the cooling crystallizer 16 and the sodium hydrogen carbonate in the absorption tower 11.
摘要翻译： 提供了一种提取分离装置，其包括：灰烬反应器12，用于通过使用含有钠，钾和氯的焚烧灰制备温度为约60℃的溶液; 冷却结晶器16，用于将溶液的温度降低至30℃以产生和分离氯化钾; 用于使溶液与含二氧化碳的气体反应以产生和分离碳酸氢钠的吸收塔11; 以及循环路径13，用于在冷却结晶器16中生产和分离氯化钾之后获得的液体和吸收塔11中的碳酸氢钠返回到灰尘反应器12。
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公开(公告)号：US08003770B2
公开(公告)日：2011-08-23
申请号：US11991964
申请日：2006-09-07
CPC分类号： C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要： A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
摘要翻译： 一种多肽，其包含由序列表的SEQ ID NO：5所示的氨基酸序列组成的多肽或由序列中一至数个氨基酸残基的缺失，添加，插入或取代的氨基酸序列组成的多肽， 能够构成HLA-A24限制性MAGE-A4143-151特异性T细胞受体的多肽以及由序列表的SEQ ID NO：2所示的氨基酸序列组成的多肽。
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公开(公告)号：US09243227B2
公开(公告)日：2016-01-26
申请号：US13431542
申请日：2012-03-27
IPC分类号： C12N5/00 , C12N5/0783 , A61K39/00 , A61K48/00
CPC分类号： C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要： The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
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公开(公告)号：US20120238012A1
公开(公告)日：2012-09-20
申请号：US13431542
申请日：2012-03-27
IPC分类号： C12N5/10 , C12N5/0783
CPC分类号： C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要： The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译： 本发明涉及具有诱导T淋巴细胞识别抗原的活性的T淋巴细胞和使用T淋巴细胞的技术。
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公开(公告)号：US20090324566A1
公开(公告)日：2009-12-31
申请号：US11991964
申请日：2006-09-07
IPC分类号： A61K45/00 , C07K14/00 , C07K16/00 , C07H21/00 , C12N15/74 , C12N5/10 , A61K31/7088 , A61P35/00
CPC分类号： C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要： A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
摘要翻译： 一种多肽，其包含由序列表的SEQ ID NO：5所示的氨基酸序列组成的多肽或由序列中一至数个氨基酸残基的缺失，添加，插入或取代的氨基酸序列组成的多肽， 能够构成HLA-A24限制性MAGE-A4143-151特异性T细胞受体的多肽以及由序列表的SEQ ID NO：2所示的氨基酸序列组成的多肽。
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公开(公告)号：US20060073126A1
公开(公告)日：2006-04-06
申请号：US11171365
申请日：2005-07-01
CPC分类号： C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要： The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译： 本发明涉及具有诱导T淋巴细胞识别抗原的活性的T淋巴细胞和使用T淋巴细胞的技术。
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