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公开(公告)号:US20110256114A1
公开(公告)日:2011-10-20
申请号:US13167414
申请日:2011-06-23
CPC分类号: C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要: A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
摘要翻译: 一种多肽,其包含由序列表的SEQ ID NO:5所示的氨基酸序列组成的多肽或由序列中一至数个氨基酸残基的缺失,添加,插入或取代的氨基酸序列组成的多肽, 能够构成HLA-A24限制性MAGE-A4143-151特异性T细胞受体的多肽以及由序列表的SEQ ID NO:2所示的氨基酸序列组成的多肽。
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公开(公告)号:US08168191B2
公开(公告)日:2012-05-01
申请号:US12113822
申请日:2008-05-01
CPC分类号: C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要: The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译: 本发明涉及具有诱导T淋巴细胞识别抗原的活性的T淋巴细胞和使用T淋巴细胞的技术。
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公开(公告)号:US08003770B2
公开(公告)日:2011-08-23
申请号:US11991964
申请日:2006-09-07
CPC分类号: C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要: A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
摘要翻译: 一种多肽,其包含由序列表的SEQ ID NO:5所示的氨基酸序列组成的多肽或由序列中一至数个氨基酸残基的缺失,添加,插入或取代的氨基酸序列组成的多肽, 能够构成HLA-A24限制性MAGE-A4143-151特异性T细胞受体的多肽以及由序列表的SEQ ID NO:2所示的氨基酸序列组成的多肽。
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公开(公告)号:US08383401B2
公开(公告)日:2013-02-26
申请号:US13167414
申请日:2011-06-23
CPC分类号: C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要: A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
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公开(公告)号:US20090068209A1
公开(公告)日:2009-03-12
申请号:US12113822
申请日:2008-05-01
CPC分类号: C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要: The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译: 本发明涉及具有诱导识别抗原的T淋巴细胞的活性的T淋巴细胞和使用T淋巴细胞的技术。
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公开(公告)号:US09243227B2
公开(公告)日:2016-01-26
申请号:US13431542
申请日:2012-03-27
IPC分类号: C12N5/00 , C12N5/0783 , A61K39/00 , A61K48/00
CPC分类号: C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要: The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
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公开(公告)号:US20120238012A1
公开(公告)日:2012-09-20
申请号:US13431542
申请日:2012-03-27
IPC分类号: C12N5/10 , C12N5/0783
CPC分类号: C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要: The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译: 本发明涉及具有诱导T淋巴细胞识别抗原的活性的T淋巴细胞和使用T淋巴细胞的技术。
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公开(公告)号:US20090324566A1
公开(公告)日:2009-12-31
申请号:US11991964
申请日:2006-09-07
IPC分类号: A61K45/00 , C07K14/00 , C07K16/00 , C07H21/00 , C12N15/74 , C12N5/10 , A61K31/7088 , A61P35/00
CPC分类号: C07K14/705 , A61K35/12 , A61K38/00 , C07K14/7051 , C12N5/0636 , C12N2501/515 , C12N2510/00
摘要: A polypeptide comprising a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 5 of Sequence Listing or a polypeptide consisting of an amino acid sequence having deletion, addition, insertion or substitution of one to several amino acid residues in the sequence, the polypeptide being capable of constituting an HLA-A24-restricted, MAGE-A4143-151-specific T cell receptor together with a polypeptide consisting of an amino acid sequence shown in SEQ ID NO: 2 of Sequence Listing.
摘要翻译: 一种多肽,其包含由序列表的SEQ ID NO:5所示的氨基酸序列组成的多肽或由序列中一至数个氨基酸残基的缺失,添加,插入或取代的氨基酸序列组成的多肽, 能够构成HLA-A24限制性MAGE-A4143-151特异性T细胞受体的多肽以及由序列表的SEQ ID NO:2所示的氨基酸序列组成的多肽。
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公开(公告)号:US20060073126A1
公开(公告)日:2006-04-06
申请号:US11171365
申请日:2005-07-01
CPC分类号: C12N5/0636 , A61K39/00 , A61K39/0011 , A61K48/00 , A61K2039/5154 , A61K2039/5156
摘要: The present invention relates to a T lymphocyte having an activity to induce a T lymphocyte recognizing an antigen and a technique to use the T lymphocyte.
摘要翻译: 本发明涉及具有诱导T淋巴细胞识别抗原的活性的T淋巴细胞和使用T淋巴细胞的技术。
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