公开(公告)号：US5008188A

公开(公告)日：1991-04-16

申请号：US117439

申请日：1987-11-04

申请人： Hideaki Yamada ,  Yoshiki Tani ,  Sakayu Shimizu ,  Shozo Shiozaki

发明人： Hideaki Yamada ,  Yoshiki Tani ,  Sakayu Shimizu ,  Shozo Shiozaki

IPC分类号： C12P19/40 ,  C12R1/01 ,  C12R1/05 ,  C12R1/06 ,  C12R1/065 ,  C12R1/13 ,  C12R1/15 ,  C12R1/20 ,  C12R1/265 ,  C12R1/29 ,  C12R1/32 ,  C12R1/365 ,  C12R1/385 ,  C12R1/465 ,  C12R1/62 ,  C12R1/625 ,  C12R1/64 ,  C12R1/645 ,  C12R1/65 ,  C12R1/66 ,  C12R1/77 ,  C12R1/78 ,  C12R1/785 ,  C12R1/80 ,  C12R1/84 ,  C12R1/845 ,  C12R1/88 ,  C12P13/12 ,  C12P19/18

CPC分类号： C12P19/40

摘要： Process for producing S-adenosyl-L-homocysteine, which comprises reacting adenosine with homocysteine by contacting them in an aqueous medium in the presence of cells or treated cells of a microorganism of a specified genus having the ability to synthesize S-adenosyl-L-homocysteine from adenosine and homocysteine, and collecting the S-adenosyl-L-homocysteine synthesized.

摘要翻译： 该方法包括使腺苷与同型半胱氨酸反应，通过在具有合成S-腺苷-L-同型半胱氨酸的能力的特定属的微生物的细胞或处理细胞的存在下在水性介质中接触， 来自腺苷和高半胱氨酸的同型半胱氨酸，并收集合成的S-腺苷-L-高半胱氨酸。

公开(公告)号：US3950453A

公开(公告)日：1976-04-13

申请号：US478995

申请日：1974-06-13

申请人： Minoru Ishiguro ,  Yuzo Takeuchi ,  Shozo Shiozaki

发明人： Minoru Ishiguro ,  Yuzo Takeuchi ,  Shozo Shiozaki

IPC分类号： C08F2/00 ,  C08F240/00 ,  C08F297/00

CPC分类号： C08F240/00

摘要： A process for preparing petroleum resins having a low melt viscosity and satisfactory compatibility, characterized by firstly polymerizing a first feed portion comprising at least one chain conjugated diolefin having 4 to 5 carbon atoms and at least one monoolefinic unsaturated hydrocarbon having 4 to 10 carbon atoms in a proportion of 20 - 80 percent by weight of the monomers contained in the first feed portion and secondly polymerizing a second feed portion comprising at least one such chain conjugated diolefin and, if desired, at least one such monoolefinic unsaturated hydrocarbon, the first and second polymerizations being successively conducted in the presence of a Friedel-Crafts type catalyst in a polymerization reactor or reactors connected in series to each other.

摘要翻译： 一种制备具有低熔体粘度和令人满意的相容性的石油树脂的方法，其特征在于首先将包含至少一个具有4至5个碳原子的链共轭二烯烃和至少一种具有4至10个碳原子的单烯属不饱和烃的第一进料部分聚合在 占第一进料部分中所含单体重量的20-80％，其次聚合第二进料部分，该第二进料部分包含至少一种这样的链共轭二烯烃，如果需要，至少一种这样的单烯烃不饱和烃，第一和第二 在Friedel-Crafts型催化剂存在下，在彼此串联连接的聚合反应器或反应器中连续进行聚合。

公开(公告)号：US4609626A

公开(公告)日：1986-09-02

申请号：US634208

申请日：1984-07-25

申请人： Hideaki Yamada ,  Sakayu Shimizu ,  Shozo Shiozaki

发明人： Hideaki Yamada ,  Sakayu Shimizu ,  Shozo Shiozaki

IPC分类号： C12N9/14 ,  C12R1/01 ,  C12R1/05 ,  C12R1/06 ,  C12R1/065 ,  C12R1/13 ,  C12R1/15 ,  C12R1/20 ,  C12R1/265 ,  C12R1/29 ,  C12R1/365 ,  C12R1/38 ,  C12R1/465 ,  C12R1/64 ,  C12R1/645 ,  C12R1/32

CPC分类号： C12N9/14 ,  Y10S435/822 ,  Y10S435/829 ,  Y10S435/83 ,  Y10S435/831 ,  Y10S435/843 ,  Y10S435/85 ,  Y10S435/863 ,  Y10S435/867 ,  Y10S435/872 ,  Y10S435/874 ,  Y10S435/886

摘要： A method for producing S-adenosyl-L-homocysteine hydrolase, which comprises cultivating a microorganism having the ability to produce S-adenosyl-L-homocysteine hydrolase within its cells in a nutrient medium to accumulate said hydrolase in the cells, said microorganism being a bacterium belonging to the genera Alcaligenes, Pseudomonas, Acinetobacter, Arthrobacter, Enterobacter, Rhodopseudomonas, Agrobacterium, Micrococcus, Corynebacterium, Brevibacterium, Chromobacterium, Xanthomonas, Flavobacterium, Cellulomonas, Azotobacter and Protaminobacter, or an actinomycete belonging to the genera Streptomyces, Mycobacterium, Nocardia, Streptoverticillium, Micromonospora, Micropolyspora, Streptosporangium and Microellobosporia; and then recovering S-adenosyl-L-homocysteine hydrolase from the cells.

摘要翻译： 一种S-腺苷-L-高半胱氨酸水解酶的制造方法，其特征在于，在营养培养基中培养具有在其细胞内产生S-腺苷-L-高半胱氨酸水解酶的能力的微生物，以在细胞中积聚所述水解酶，所述微生物为 属于产碱杆菌属，假单胞菌属，不动杆菌属，节杆菌属，肠杆菌属，红假单胞菌属，土壤杆菌属，微球菌属，棒状杆菌属，短杆菌属，色杆菌属，黄单胞菌属，黄杆菌属，单核细菌属，固氮菌属和Protaminobacter属的细菌或属于链霉菌属，分枝杆菌属，诺卡氏菌属， 链霉菌，小单孢菌，微孢子虫，链球菌属和微球菌属; 然后从细胞中回收S-腺苷-L-高半胱氨酸水解酶。

公开(公告)号：US4020260A

公开(公告)日：1977-04-26

申请号：US557128

申请日：1975-03-10

申请人： Shozo Shiozaki ,  Yonesaku Shinohara ,  Takeo Miyake

发明人： Shozo Shiozaki ,  Yonesaku Shinohara ,  Takeo Miyake

IPC分类号： C08F2/00 ,  C08F2/04 ,  C08F32/00 ,  C08F36/00 ,  C08F236/04 ,  C08F4/00 ,  C08F232/00 ,  C08L7/00

CPC分类号： C08F236/045

摘要： Hydrocarbon resins comprising about 95-35% by weight of units derived from 1,3-pentadiene, about 1-50% by weight of units derived from cyclododecatriene, and O-about 40% by weight of units derived from at least one monoolefin containing 5 carbon atoms, having a softening point of from about 100.degree. to about 160.degree. C., and being substantially gel-free. The hydrocarbon resins can be prepared by polymerizing a monomeric mixture comprising 1,3-pentadiene in the presence of a Friedel-Crafts type metal halide catalyst, said monomeric mixture comprising about 95-35% by weight of 1,3-pentadiene, about 1-50% by weight of cyclododecatriene, and 0-about 50% by weight of at least one monoolefin containing 5 carbon atoms.

摘要翻译： 包含约95-35重量％的衍生自1,3-戊二烯的单元，约1-50重量％衍生自环十二碳三烯的单元的烃树脂和约40重量％的衍生自至少一种含有 5个碳原子，软化点为约100至约160℃，基本上不含凝胶。 烃树脂可以通过在Friedel-Crafts型金属卤化物催化剂的存在下聚合包含1,3-戊二烯的单体混合物来制备，所述单体混合物包含约95-35％（重量）的1,3-戊二烯，约1 -50重量％的环十二碳三烯和0-约50重量％的至少一种含有5个碳原子的单烯烃。

公开(公告)号：US4605625A

公开(公告)日：1986-08-12

申请号：US706393

申请日：1985-02-27

申请人： Hideaki Yamada ,  Sakayu Shimizu ,  Shozo Shiozaki

发明人： Hideaki Yamada ,  Sakayu Shimizu ,  Shozo Shiozaki

IPC分类号： C12N9/14 ,  C12P13/04 ,  C12P19/40 ,  C12R1/385 ,  C12R1/40 ,  C12P19/26 ,  C12P19/28

CPC分类号： C12P13/04 ,  C12N9/14 ,  C12P19/40 ,  Y10S435/829 ,  Y10S435/874 ,  Y10S435/877 ,  Y10S435/929 ,  Y10S435/94

摘要： S-adenosyl-L-homocysteine is produced by contacting adenosine with D-homocysteine in an aqueous medium in the presence of cells or treated cells of a microorganism of the genus Pseudomonas having the ability to racemize D-homocysteine to DL-homocysteine and in the presence of S-adenosyl-L-homocysteine hydrolase, to synthesize S-adenosyl-L-homocysteine, and thereafter collecting it.

摘要翻译： S-腺苷-L-高半胱氨酸是通过在具有将D-高半胱氨酸外消旋化为DL-同型半胱氨酸的能力的假单胞菌属的微生物的细胞或处理细胞的存在下在水性介质中将腺苷与D-高半胱氨酸接触而产生的， 存在S-腺苷-L-高半胱氨酸水解酶，合成S-腺苷-L-高半胱氨酸，然后收集。

公开(公告)号：US4562149A

公开(公告)日：1985-12-31

申请号：US463990

申请日：1983-02-04

申请人： Shozo Shiozaki ,  Hideaki Yamada ,  Yoshiki Tani ,  Sakayu Shimizu

发明人： Shozo Shiozaki ,  Hideaki Yamada ,  Yoshiki Tani ,  Sakayu Shimizu

IPC分类号： C12N1/18 ,  C12P19/40 ,  C12P13/12 ,  C12N1/16 ,  C12P19/32

CPC分类号： C12P19/40 ,  C12N1/18 ,  Y10S435/94 ,  Y10S435/942

摘要： A yeast culture containing at least 10% by weight, based on the dry cell, of S-adenosyl methionine; and a process for producing S-adenosyl methionine, which comprises cultivating a yeast having the ability to produce S-adenosyl methionine in a liquid culture medium containing methionine to accumulate at least 10% by weight, based on the dry yeast cells, of S-adenosyl methionine in the yeast cells, separating the yeast cells from the culture medium, and thereafter obtaining S-adenosyl methionine in a stable form from the yeast cells.

摘要翻译： 含有至少10重量％的基于干细胞的S-腺苷甲硫氨酸的酵母培养物; 以及生产S-腺苷甲硫氨酸的方法，其包括在含有甲硫氨酸的液体培养基中培养具有产生S-腺苷甲硫氨酸能力的酵母以基于所述干酵母细胞累积至少10重量％的S- 腺苷甲硫氨酸，从培养基中分离酵母细胞，然后从酵母细胞中获得稳定形式的S-腺苷甲硫氨酸。