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公开(公告)号：US20170340785A1
公开(公告)日：2017-11-30
申请号：US15521040
申请日：2014-10-23
CPC分类号： A61M1/0281 , A61M1/3692 , A61M1/3696 , A61M2205/12 , B04B5/0442 , B04B7/00 , B04B7/08
摘要： An autotransfusion system for separating fluid constituents includes a centrifuge housing and a rotatable driving member mounted within the centrifuge housing. The rotatable driving member is configured to receive therein and rotationally engage any one of a plurality of centrifuge bowls with different heights. In some embodiments, the centrifuge bowl is integrated with a fluid line organizer to provide for easy and efficient organization of a plurality of different fluid lines incorporated into the autotransfusion system. In some embodiments, the centrifuge bowl and fluid line organizer are easily and efficiently coupled to the centrifuge housing for autotransfusion processing.
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公开(公告)号：US20170319767A1
公开(公告)日：2017-11-09
申请号：US15525853
申请日：2014-11-12
发明人： Andrea Zaniboni , Sara Menozzi , Francesco Benatti
CPC分类号： A61M1/1698 , B01D53/22 , B01D63/02 , B01D2313/23 , B01D2313/56
摘要： A blood processing apparatus includes a housing, a shell, a fiber bundle, and an elastic tube. The housing has a blood inlet and a blood outlet and the shell is situated in the housing and configured to receive blood through the blood inlet. The shell includes a surface and one or more apertures extending through the surface to permit the blood to flow to an exterior of the shell. The fiber bundle includes gas exchanger hollow fibers situated about the shell such that gas flows through and the blood flows across the gas exchanger hollow fibers. The elastic tube includes a fiber web situated about the fiber bundle and configured to elastically constrain and protect the gas exchanger hollow fibers during the insertion into the housing. The fiber web has a pore size that permits the blood to flow across the fiber web without filtering micro-emboli from the blood.
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3.发明申请Holder for heart valve prostheses, corresponding storage arrangement, delivery instrument and kit 有权心脏瓣膜假体支架，相应的储存装置，输送仪器和试剂盒公开(公告)号：US20160128819A1
公开(公告)日：2016-05-12
申请号：US14998237
申请日：2015-12-23
CPC分类号： A61F2/0095 , A61B50/30 , A61B2050/3005 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2002/9522 , B65D81/02 , B65D81/18
摘要： Disclosed herein are various embodiments of a holder (1) for heart valve prostheses (V). Embodiments of the holder (1) include: a hub portion (2) having a longitudinal axis (X1), an engagement portion (4) coupled to the hub portion (2) and including plural finger members (5) variably positionable relative to the hub portion (2) between a collapsed condition wherein the finger members (5) are closed onto the hub portion (2) and an expanded condition wherein the finger members (5) radially protrude with respect to the hub portion (2) to engage a heart valve prosthesis (V). The finger members (5) are L-shaped.Also disclosed are a storage arrangement and delivery instrument and a kit for crimping, loading and delivering an expandable heart valve prosthesis (V).
摘要翻译： 这里公开了用于心脏瓣膜假体（V）的保持器（1）的各种实施例。 保持器（1）的实施例包括：具有纵向轴线（X1）的毂部分（2），联接到轮毂部分（2）的接合部分（4），并且包括相对于所述轮毂部分（2）可变地定位的多个指状构件 在其中手指构件（5）关闭到轮毂部分（2）上的折叠状态和扩张状态之间的轮毂部分（2），其中指状构件（5）相对于轮毂部分（2）径向突出以接合 心脏瓣膜假体（V）。 指状构件（5）为L形。 还公开了一种存储装置和递送装置以及用于卷曲，装载和递送可膨胀心脏瓣膜假体（V）的套件。
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公开(公告)号：US20130261742A1
公开(公告)日：2013-10-03
申请号：US13849461
申请日：2013-03-22
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/0095 , A61F2/2412 , A61F2002/9522
摘要： A kit for facilitating crimping of a prosthetic heart valve for implantation at an aortic valve site in a human heart, the aortic valve site including a plurality of valve sinuses, the kit comprising a prosthetic aortic heart valve having a tubular structure and a first central axis including an anchoring structure comprising an annular outflow member, an annular inflow member, and a plurality of axial connection formations arranged in pairs angularly distributed around the central axis, and a plurality of leaflets coupled to the anchoring structure and adapted to substantially allow blood flow in a first direction and to substantially prevent blood flow in a second direction. The kit further includes a holder member comprising a first disc support member that includes a central hub and a plurality of bridge elements, wherein the hub and the bridge elements extend axially from opposite sides of the disc support member; and a second ring support member that includes receptacles for coupling with the bridge elements, and a plurality of finger formations protruding axially from the ring member and extending lengthwise along at least a portion of the prosthetic aortic heart valve.
摘要翻译： 一种用于促进假体心脏瓣膜的压接以用于植入人心脏中的主动脉瓣部位的试剂盒，所述主动脉瓣部位包括多个瓣膜窦，该试剂盒包括具有管状结构的假体主动脉瓣心脏瓣膜和第一中心轴线 包括锚定结构，其包括环形流出构件，环形流入构件以及围绕所述中心轴线成角度地分布成对的多个轴向连接结构，以及耦合到所述锚定结构并且适于基本上允许血液流动的多个叶片 第一方向并且基本上防止在第二方向上的血液流动。 该套件还包括保持器构件，其包括第一盘支撑构件，该第一盘支撑构件包括中心轮毂和多个桥接元件，其中轮毂和桥接元件从盘支撑构件的相对侧轴向延伸; 以及第二环支撑构件，其包括用于与所述桥接元件联接的插座，以及从所述环构件轴向突出并沿所述假体主动脉瓣心脏的至少一部分纵向延伸的多个指状结构。
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5.发明授权公开(公告)号：US10293098B2
公开(公告)日：2019-05-21
申请号：US16127662
申请日：2018-09-11
发明人： Elisa Maculan , Laura Scholze
摘要： A system for removing undesirable elements from blood. The system includes a centrifuge bowl to separate the blood into components according to relative densities of the components, a pump to provide wash solution that washes the blood in the centrifuge bowl, and a controller to wash the blood in the centrifuge bowl in a first wash and remove first undesirable elements and to wash the blood in the centrifuge bowl in a second wash and remove trapped undesirable elements. The controller to further mix the blood and the wash solution in the centrifuge bowl and provide diluted blood, separate the diluted blood into concentrated blood and the wash solution, fill the centrifuge bowl with previously concentrated blood to build a buffy coat, and empty the centrifuge bowl of the concentrated blood and the previously concentrated blood after the buffy coat is reached.
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公开(公告)号：US20150051698A1
公开(公告)日：2015-02-19
申请号：US14325746
申请日：2014-07-08
IPC分类号： A61F2/24
CPC分类号： A61F2/2457 , A61F2/2412 , A61F2/2445 , A61F2/2448 , A61F2/2466
摘要： Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.
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公开(公告)号：US09155622B2
公开(公告)日：2015-10-13
申请号：US14325746
申请日：2014-07-08
IPC分类号： A61F2/24
CPC分类号： A61F2/2457 , A61F2/2412 , A61F2/2445 , A61F2/2448 , A61F2/2466
摘要： Described is a prosthetic device and methods for repairing a mitral valve having an annulus, leaflets, and chordae tendinae. The device comprises an elongate band including a plurality of reference elements that are located along the elongate band and protrude inwardly with respect thereto towards a center of the annulus, the plurality of reference elements being adapted to receive a corresponding plurality of artificial cords that are tied onto the reference elements and the plurality of reference elements adapted to be cut or removed in order to release the tied artificial cords.
摘要翻译： 描述了一种修复装置和修复具有环状，小叶和腱索的二尖瓣的方法。 该装置包括细长带，其包括沿着细长带定位并相对于其朝向环的中心向内突出的多个参考元件，多个参考元件适于接收相应的多个被连接的人造绳 到参考元件和适于被切割或移除的多个参考元件以便释放被连接的人造绳。
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公开(公告)号：US20170156866A1
公开(公告)日：2017-06-08
申请号：US15433970
申请日：2017-02-15
CPC分类号： A61F2/2496 , A61B5/02 , A61B5/103 , A61B5/1076 , A61B5/6871
摘要： A device for measuring an internal dimension of a native cardiac valve annulus includes an elongated support member having a proximal portion and a distal portion. A measuring portion is coupled to the distal portion, and an indicator is coupled to the proximal portion of the support member. The measuring portion is biased towards a deployed configuration such that when deployed it applies an outwardly directed radial force to the native valve annulus.
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公开(公告)号：US20140188217A1
公开(公告)日：2014-07-03
申请号：US14176533
申请日：2014-02-10
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/06 , A61F2/064 , A61F2/2409 , A61F2/2427 , A61F2/2436 , A61F2002/9522 , Y10T29/49412
摘要： A kit for implanting a prosthetic vascular conduit includes a prosthetic vascular conduit for coupling to a prosthetic valve having an annular portion. The conduit includes a terminal collar member for receiving the valve. The kit further includes a holder including a shaft and a hub including a receiving portion configured for housing a prosthetic valve. The conduit is fitted on the holder so that at least a portion of the conduit wraps over the receiving portion of the hub. A sleeve member fitted onto the conduit in a position corresponding to the receiving portion of the hub, and a portion of the collar member is wrapped or folded over the sleeve member. The sleeve member is slidable away from the hub to unwrap the collar member such that it is disposed around the annular portion of a prosthetic valve.
摘要翻译： 用于植入假体血管导管的套件包括用于联接到具有环形部分的假体瓣膜的假体血管导管。 导管包括用于接收阀的端子套环构件。 套件还包括保持器，其包括轴和毂，包括构造成容纳人造瓣膜的接收部分。 导管安装在保持器上，使得至少一部分导管缠绕在毂的接收部分上。 套筒构件在对应于轮毂的接收部分的位置中安装到导管上，并且套环构件的一部分被卷绕或折叠在套筒构件上。 套筒构件可以从轮毂滑动以展开套环构件，使得其围绕假肢瓣膜的环形部分设置。
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公开(公告)号：US20130345800A1
公开(公告)日：2013-12-26
申请号：US13972022
申请日：2013-08-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/2469 , A61F2/848 , A61F2210/0014 , A61F2220/0008 , A61F2220/0075 , A61F2230/0054 , A61F2250/001 , Y10T29/49833
摘要： A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site.
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