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公开(公告)号：US09329112B2
公开(公告)日：2016-05-03
申请号：US13982312
申请日：2012-01-25
CPC分类号： G01N1/42 , B01L3/508 , B01L2200/0647 , B01L2200/16 , B01L2300/06 , B01L2300/0829 , B01L2300/0832 , Y10T436/2525
摘要： A container holding, and a method of storing, freeze-dried biological samples. The container includes a chamber having an upper portion and a lower portion. The chamber includes a wall, and the lower portion of the chamber is fluidly connected to the upper portion of the chamber such that, when liquid is received at the upper portion, the received liquid can pass to and accumulate in the lower portion. Further, the freeze-dried material is located in the lower portion, and the container includes a physical structure in the form of a stop protruding inwards from the wall, the physical structure being for inhibiting the freeze-dried material from moving from the lower portion of the chamber to the upper portion of the chamber.
摘要翻译： 容器的容器，以及冷冻干燥的生物样品的储存方法。 容器包括具有上部和下部的腔室。 腔室包括壁，腔室的下部流体地连接到腔室的上部，使得当液体在上部被容纳时，所接收的液体可以传递并且积聚在下部。 此外，冷冻干燥材料位于下部，容器包括从壁向内突出的止挡件形式的物理结构，该物理结构用于抑制冻干材料从下部移动 的腔室的上部。
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公开(公告)号：USD709210S1
公开(公告)日：2014-07-15
申请号：US29402999
申请日：2011-09-30
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公开(公告)号：USD705444S1
公开(公告)日：2014-05-20
申请号：US29403000
申请日：2011-09-30
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公开(公告)号：US20130284680A1
公开(公告)日：2013-10-31
申请号：US13996604
申请日：2011-12-20
CPC分类号： B01D33/01 , B01D29/118 , B01L3/00 , B01L3/502 , B01L3/508 , B01L2200/0684 , B01L2200/141 , B01L2300/0681 , B01L2300/0832 , B01L2400/0478
摘要： Embodiments of the present invention relate to a filtration device and method for filtering liquids. In conventional devices, a liquid is placed in a vial, and a plunger, having a filter membrane located at one end, is depressed into the vial, causing the liquid to pass through the filter membrane into the interior of the plunger, where it is stored until required for further processing. However, such plungers are typically made of a plastics material. It is undesirable to store the filtered liquid in contact with plastics for extended periods of time, as contaminants may leach from the plastics material into the sample. In embodiments of the present invention, a filtrate receptacle made from a different material to the plunger, such as a glass material, is located in the interior of the plunger and the filtered liquid collected in the filtrate receptacle after passing through the filter membrane. This allows the filtered liquid to be held isolated from the plastics material, thereby protecting it from contamination.
摘要翻译： 本发明的实施例涉及一种用于过滤液体的过滤装置和方法。 在常规装置中，将液体放置在小瓶中，并且具有位于一端的过滤膜的柱塞被压入小瓶中，使得液体通过过滤膜进入柱塞的内部，其中 存储直到进一步处理为止。 然而，这种柱塞通常由塑料材料制成。 将过滤的液体与塑料接触较长时间是不希望的，因为污染物可能从塑料材料浸出到样品中。 在本发明的实施例中，由与柱塞不同的材料（例如玻璃材料）制成的滤液容器位于柱塞的内部，并且滤过的液体在通过过滤膜之后被收集在滤液容器中。 这使得过滤的液体被保持与塑料材料隔离，从而防止其被污染。
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公开(公告)号：US20130260477A1
公开(公告)日：2013-10-03
申请号：US13990144
申请日：2011-11-24
IPC分类号： B01L3/00
CPC分类号： B01L3/508 , B01L9/52 , B01L2200/025 , B01L2200/12 , B01L2300/02 , B01L2300/069 , B01L2300/0819 , B01L2300/0822 , G01N1/312 , G01N35/00732 , Y10T436/25
摘要： Embodiments of the invention relate to methods of assembling an apparatus for holding biological samples. Conventionally, storage media are encased in a relatively thin flexible cardboard frame. Such constructions are vulnerable to damage from moisture and mechanical forces; these defects may subsequently cause problems for automated handling systems. In an embodiment, these defects are prevented by providing a pair of rigid frames, each frame comprising an aperture; placing a biological sample storage medium between the two frames so that the biological sample storage medium at least partly overlaps each of the apertures in the frames; and joining the two frames to fix the biological sample storage medium in place while allowing access to the biological sample storage medium via each of the apertures. Thus, in embodiments of the present invention, the frames can be rigid and waterproof, and provide a robust storage media for biological samples. At least one pre-defined area of weakness can be provided in the frames, to allow removal of a portion of the frames.
摘要翻译： 本发明的实施例涉及组装用于保持生物样品的装置的方法。 通常，存储介质被封装在相对薄的柔性纸板框架中。 这种结构容易受到水分和机械力的损害; 这些缺陷可能随后引起自动化处理系统的问题。 在一个实施例中，通过提供一对刚性框架来防止这些缺陷，每个框架包括孔; 将生物样品存储介质放置在两个框架之间，使得生物样品存储介质至少部分地与框架中的每个孔重叠; 并且连接两个框架以将生物样品存储介质固定到位，同时允许经由每个孔进入生物样品存储介质。 因此，在本发明的实施例中，框架可以是刚性和防水的，并为生物样品提供坚固的存储介质。 可以在框架中提供至少一个预定义的弱点区域，以允许移除框架的一部分。
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公开(公告)号：USD686340S1
公开(公告)日：2013-07-16
申请号：US29415882
申请日：2012-03-15
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7.发明授权Controlled transfer biological sample collection devices and methods of using such devices 有权受控转移生物样品收集装置和使用这种装置的方法公开(公告)号：US08468901B2
公开(公告)日：2013-06-25
申请号：US12449603
申请日：2008-02-15
申请人： Michael A. Harvey , Breck O. Parker , Stevan Paul Tortorella , Elizabeth A. Moran , John Pipinias
发明人： Michael A. Harvey , Breck O. Parker , Stevan Paul Tortorella , Elizabeth A. Moran , John Pipinias
IPC分类号： B01L3/00
CPC分类号： B01L9/00 , B01L3/5023 , B01L3/505 , B01L2200/027 , B01L2300/069 , G01N1/02 , G01N2001/028 , G01N2035/00356
摘要： The field of the present invention pertains to a controlled transfer biological collection device using a dry solid storage and transfer medium and a method for the collection of biological material of interest (genetic or proteinaceous material) in a form suitable for storage and/or subsequent analysis. Specifically, the present invention provides for a sampling device that controls the transfer of the biological sample to the storage medium by holding the storage medium and a moveable sample collection cmember having an analyte collection surface. The invention further provides for a method not only for storing a biological analyte on this collection device but also for analyzing the stored biological analyte using methods that are suited for automated analyzing systems.
摘要翻译： 本发明的领域涉及使用干燥固体储存和转移介质的受控转移生物收集装置和用于以适于储存和/或随后分析的形式收集目的生物材料（遗传或蛋白质材料）的方法 。 具体地，本发明提供一种采样装置，其通过保持存储介质和具有分析物收集表面的可移动的样品收集组件来控制生物样品向存储介质的转移。 本发明还提供了不仅用于将生物分析物储存在该收集装置上的方法，而且还用于使用适合于自动分析系统的方法分析储存的生物分析物的方法。
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公开(公告)号：US10155183B2
公开(公告)日：2018-12-18
申请号：US13996604
申请日：2011-12-20
摘要： Embodiments of the present invention relate to a filtration device and method for filtering liquids. In conventional devices, a liquid is placed in a vial, and a plunger, having a filter membrane located at one end, is depressed into the vial, causing the liquid to pass through the filter membrane into the interior of the plunger, where it is stored until required for further processing. However, such plungers are typically made of a plastics material. It is undesirable to store the filtered liquid in contact with plastics for extended periods of time, as contaminants may leach from the plastics material into the sample. In embodiments of the present invention, a filtrate receptacle made from a different material to the plunger, such as a glass material, is located in the interior of the plunger and the filtered liquid collected in the filtrate receptacle after passing through the filter membrane. This allows the filtered liquid to be held isolated from the plastics material, thereby protecting it from contamination.
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公开(公告)号：US09534990B2
公开(公告)日：2017-01-03
申请号：US14005909
申请日：2012-03-15
CPC分类号： G01N1/312 , B01L3/5029 , B01L3/5055 , B01L7/00 , B01L2200/0678 , B01L2300/0822 , G01N1/2813 , G01N1/44 , G01N2001/2826 , G01N2001/4027 , Y10T436/2525
摘要： The present invention generally relates to systems and methods for preserving biological samples and, more particularly, an arrangement for drying biological samples disposed on sample storage substrates. The systems and methods for preserving biological samples can include a heating element such as a chemical heating pad that facilitates drying of the biological samples.
摘要翻译： 本发明一般涉及用于保存生物样品的系统和方法，更具体地说，涉及一种用于干燥设置在样品存储基底上的生物样品的装置。 用于保存生物样品的系统和方法可以包括加热元件，例如促进生物样品干燥的化学加热垫。
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公开(公告)号：US09433942B2
公开(公告)日：2016-09-06
申请号：US13990144
申请日：2011-11-24
CPC分类号： B01L3/508 , B01L9/52 , B01L2200/025 , B01L2200/12 , B01L2300/02 , B01L2300/069 , B01L2300/0819 , B01L2300/0822 , G01N1/312 , G01N35/00732 , Y10T436/25
摘要： Apparatus for holding biological samples and methods of assembling the same are disclosed. In an embodiment, a pair of rigid frames is described, each frame comprising an aperture. A biological sample storage medium is placed between the two frames so that the biological sample storage medium at least partly overlaps each of the apertures in the frames. The two frames are joined to fix the biological sample storage medium in place while allowing access to the biological sample storage medium via each of the apertures. The frames can be rigid and waterproof, and provide a robust storage media for biological samples. At least one pre-defined area of weakness can be provided in the frames, to allow removal of a portion of the frames, which may correspond to indicia on the storage medium.
摘要翻译： 公开了用于保持生物样品的装置及其组装方法。 在一个实施例中，描述了一对刚性框架，每个框架包括孔。 将生物样品存储介质放置在两个框架之间，使得生物样品存储介质至少部分地与框架中的每个孔重叠。 连接两个框架以将生物样品存储介质固定就位，同时允许经由每个孔进入生物样品存储介质。 框架可以是刚性和防水的，并为生物样品提供坚固的存储介质。 可以在框架中提供至少一个预定义的弱点区域，以允许去除可能对应于存储介质上的标记的框架的一部分。
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