公开(公告)号：US12024539B1

公开(公告)日：2024-07-02

申请号：US17090365

申请日：2020-11-05

Applicant: Subhajit Dasgupta

Inventor： Subhajit Dasgupta

IPC: C07K14/00 ,  G16B5/00

CPC classification number: C07K14/001 ,  G16B5/00

Abstract: The invented non-homologous peptide sequences are able to form dimers with corresponding amyloid beta (Aβ), its precursor protein (APP) and enzyme gamma secretase (GSA) as observed by using fixed z-axis overlay computer modeling. [The dipole moment values of these dimeric peptide structures are increased with respect to individual Aβ peptide (1-42) and APP fragments].

公开(公告)号：US11613562B2

公开(公告)日：2023-03-28

申请号：US17346245

申请日：2021-06-13

Applicant: Subhajit Dasgupta

Inventor： Subhajit Dasgupta

IPC: C07K14/165

Abstract: The multi-epitope SARS-COV2 Spike peptides are analyzed for their ability to form association or binding complex with HLA-DR1 and human TLR8 by using computer modeling and molecular docking experiments. These peptides are identified as candidates for vaccine development as well as antibody-based immunotherapy.

公开(公告)号：US20220098245A1

公开(公告)日：2022-03-31

申请号：US17346245

申请日：2021-06-13

Applicant: Dr. Subhajit Dasgupta

Inventor： Subhajit Dasgupta

IPC: C07K14/165

Abstract: The multi-epitope SARS-COV2 Spike peptides are analyzed for their ability to form association or binding complex with HLA-DR1 and human TLR8 by using computer modeling and molecular docking experiments. These peptides are identified as candidates for vaccine development as well as antibody-based immunotherapy.

公开(公告)号：US20230250136A1

公开(公告)日：2023-08-10

申请号：US17736755

申请日：2022-05-04

Applicant: Dr. Subhajit Dasgupta

Inventor： Subhajit Dasgupta

IPC: C07K14/165 ,  A61P31/14

CPC classification number: C07K14/165 ,  A61P31/14

Abstract: The identified peptide sequences form moderate to strong heterodimeric complexes with SARS-COV2 (B.1.617.2) virus Spike envelope proteins and a range of virus nonstructural protein sequences NSP1-14. These identified peptides are proposed to use in antiviral immunotherapy and supportive combination with chemical compound(s) for chemotherapy. The sequence ID of the identified peptides are, Seq1: ISD1, Seq2: ISD2, Seq3: ISD3, Seq4: ISD4, Seq5: ISD5, Seq6: ISD6, Seq7 Ip2, Seq8: Ip1, Seq9: Ip3, Seq10: Ip5, Seq11: Ip7, Seq12: Ip8, Seq13: Ip9, Seq14: SOI1, Seq15: SOI2, Seq16: SOI5, Seq17: SOI7, Seq18: SOI9, Seq19: SO10, Seq20: SO11.

公开(公告)号：US20180308272A1

公开(公告)日：2018-10-25

申请号：US15493195

申请日：2017-04-21

Applicant: Abhishek R. Appu ,  Prasoonkumar Surti ,  Srivallaba Mysore ,  Subhajit Dasgupta ,  Hiroshi Akiba ,  Eric J. Hoekstra ,  Linda L. Hurd ,  Travis T. Schluessler ,  Daren J. Schmidt

Inventor： Abhishek R. Appu ,  Prasoonkumar Surti ,  Srivallaba Mysore ,  Subhajit Dasgupta ,  Hiroshi Akiba ,  Eric J. Hoekstra ,  Linda L. Hurd ,  Travis T. Schluessler ,  Daren J. Schmidt

IPC: G06T15/00 ,  G06F9/54 ,  G06F1/32 ,  G06T15/50

CPC classification number: G06T15/005 ,  G06T1/20 ,  G06T15/503

Abstract: Briefly, in accordance with one or more embodiments, a processor receives an incoming data stream that includes alpha channel data, and a memory stores an application programming interface (API). The API is to route the alpha channel data to a fixed point blending unit to perform one or more blending operations using fixed point representation of the alpha channel data. The API is further to route the incoming data stream to a floating point blending unit to perform operations involving floating point representation of the incoming data.

公开(公告)号：US07080168B2

公开(公告)日：2006-07-18

申请号：US10622285

申请日：2003-07-18

Applicant: Subhajit Dasgupta ,  Jaisimha Bannur ,  Anujan Varma

Inventor： Subhajit Dasgupta ,  Jaisimha Bannur ,  Anujan Varma

IPC: G06F3/00

CPC classification number: H04L49/254 ,  H04L47/50 ,  H04L47/522 ,  H04L47/621 ,  H04L47/6255

Abstract: In general, in one aspect, the disclosure describes an apparatus that includes a plurality of flow controllable queues containing data to be transmitted. The queues are organized by flow. The apparatus also includes a plurality of destinations to receive data from the plurality of queues. The apparatus further includes a controller to continually maintain an aggregate count of data ready for transmission to the destinations and determine next queue to transmit data from based at least partially on the aggregate counts.

Abstract translation: 一般来说，一方面，本公开描述了一种包括多个可流式控制的队列的装置，其包含要发送的数据。 队列按流程组织。 该装置还包括从多个队列接收数据的多个目的地。 该装置还包括控制器，用于连续地维护准备好传输到目的地的数据的聚合计数，并且确定下一个队列以至少部分地基于总计数传送数据。

公开(公告)号：US20050015388A1

公开(公告)日：2005-01-20

申请号：US10622285

申请日：2003-07-18

Applicant: Subhajit Dasgupta ,  Jaisimha Bannur ,  Anujan Varma

Inventor： Subhajit Dasgupta ,  Jaisimha Bannur ,  Anujan Varma

IPC: G06F7/00 ,  H04L12/56

CPC classification number: H04L49/254 ,  H04L47/50 ,  H04L47/522 ,  H04L47/621 ,  H04L47/6255

Abstract: In general, in one aspect, the disclosure describes an apparatus that includes a plurality of flow controllable queues containing data to be transmitted. The queues are organized by flow. The apparatus also includes a plurality of destinations to receive data from the plurality of queues. The apparatus further includes a controller to continually maintain an aggregate count of data ready for transmission to the destinations and determine next queue to transmit data from based at least partially on the aggregate counts.

Abstract translation: 一般来说，一方面，本公开描述了一种包括多个可流式控制的队列的装置，其包含要发送的数据。 队列按流程组织。 该装置还包括从多个队列接收数据的多个目的地。 该装置还包括控制器，用于连续地维护准备好传输到目的地的数据的聚合计数，并且确定下一个队列以至少部分地基于总计数传送数据。

公开(公告)号：US20240409525A1

公开(公告)日：2024-12-12

申请号：US18207440

申请日：2023-06-08

Applicant: Subhajit Dasgupta

Inventor： Subhajit Dasgupta

IPC: C07D311/30 ,  C07D213/04 ,  C07D309/18

Abstract: The computer guided digital platform screened out test compounds in a cell free system using Molecular Docking and Molecular Dynamics. The experimental outcomes demonstrate complex structure formation between the test compounds Rhamnetin, Rosyrane, N-retinylidene-N-retinylethanolamine, Hesperidin, Trihydroxybutyrate, Trihydroxyflavone, Arylaminoethylamide with human Presenilin- and Amyloid Precursor Protein (APP). The compounds also demonstrate the ability to bind with amyloid beta (1-42) peptide. Trihydroxyflavone and its family, and arylaminoethylamide can modulate neurotransmitter release as the test compounds bind with synaptic vesicular protein VAT-1.

公开(公告)号：US11010953B2

公开(公告)日：2021-05-18

申请号：US15493195

申请日：2017-04-21

Applicant: Abhishek R. Appu ,  Prasoonkumar Surti ,  Srivallaba Mysore ,  Subhajit Dasgupta ,  Hiroshi Akiba ,  Eric J. Hoekstra ,  Linda L. Hurd ,  Travis T. Schluessler ,  Daren J. Schmidt

Inventor： Abhishek R. Appu ,  Prasoonkumar Surti ,  Srivallaba Mysore ,  Subhajit Dasgupta ,  Hiroshi Akiba ,  Eric J. Hoekstra ,  Linda L. Hurd ,  Travis T. Schluessler ,  Daren J. Schmidt

IPC: G06T15/00 ,  G06T15/50 ,  G06T1/20 ,  G06F1/3287 ,  G06F9/54

Abstract: Briefly, in accordance with one or more embodiments, a processor receives an incoming data stream that includes alpha channel data, and a memory stores an application programming interface (API). The API is to route the alpha channel data to a fixed point blending unit to perform one or more blending operations using fixed point representation of the alpha channel data. The API is further to route the incoming data stream to a floating point blending unit to perform operations involving floating point representation of the incoming data.