Abstract:
The present invention relates to a process for the preparation of Pasireotide of formula (I) and its acid addition salts. More particularly the present invention is directed to a process for the synthesis of Pasireotide of formula (I) having purity greater than 99.0% by HPLC using fragment coupling.
Abstract:
The present invention relates to a process for the preparation of Liraglutide, which comprises: a) synthesis of suitable fragments (protected) by solid phase peptide synthesis; b) coupling of the suitable fragments on solid support; c) concurrently cleaving the protected peptide from the solid support and de-protecting the peptide; d) purification of Liraglutide (crude) on reverse phase HPLC; e) isolating pure Liraglutide.
Abstract:
This disclosure provides a system of intelligent lights together with control devices and sensors communicating over a wireless network, with methods to allow the lights to take actions based on logical combinations of events generated by other devices. The lights can function autonomously as they have built-in functions of logic processing, storage and wireless communications which allow them to receive events and take actions according to the stored logic configuration data. Complete freedom in the grouping of lights as well as association of control devices and sensors to each individual lights is enabled by this system architecture. Seamless communication coverage is enabled by a wireless protocol that allows the light to form a mesh network. The discovery of devices in the network and their capabilities/services, as well as the setting up of the logic configuration data for the lights, are performed by a smart phone or similarly device with user interface, which facilitates simpler hardware for the lights as well as making it easy to add new devices and discovering their capabilities/services. Additional functions of the intelligent lights are location-based services using periodic broadcast data packets transmitted from the lights, as well as receiving broadcast data packets from other devices.
Abstract:
A method of temperature control in a cryogenic temperature control apparatus. The method includes operating the cryogenic temperature control apparatus in a first mode, and delivering a first flow rate of cryogen from a storage tank to an evaporator coil in the first mode. The cryogenic temperature control apparatus is operated in a second mode after operating the cryogenic temperature control apparatus in the first mode for a predetermined time duration. A second flow rate of cryogen that is lower than the first flow rate is delivered to the evaporator coil in the second mode.
Abstract:
A printed circuit antenna has a feedline region and a radiating structure region. The feedline region is formed of conductors on an upper plane, the conductors including a feedline which is edge coupled to a left ground structure and a right ground structure, all of which are above a ground plane. Upper highband RF is coupled from the RF feedline to a first segment, a second segment, and a third segment. For lowband RF frequencies, RF is coupled from the feedline to the first segment and stub, across a gap to a fourth segment, a fifth segment LB radiating structure, a fifth segment common radiating structure, and to a sixth segment common radiating structure which is grounded. For lower highband RF frequencies, RF is coupled from the feedline to the first segment and stub to a sixth segment common radiating structure, fifth segment, bridge, seventh segment, and eighth segment.
Abstract:
An access control system that utilizes a combination of passive tags and active RFIDs. The system may combine passive and active circuitry in one package or may be separable. The system may incorporate legacy passive access control tags. An access control tag may be associated with a network protocol ID.
Abstract:
In some example embodiments, a graphical user interface (GUI) is caused to be displayed on a computing device of a user. The GUI can be configured to enable the user to submit an identification of a dataset and at least one configuration parameter. The identification of the data source, the at least one configuration parameter, and the at least one wrangling parameter can be received via the GUI on the computing device. A sampling algorithm can be configured based on the at least one configuration parameter. A sample of data from the dataset can be generated using the configured sampling algorithm. At least one data wrangling operation can be performed on the sample of data based on the at least one wrangling parameter.
Abstract:
The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.
Abstract:
A node is configured to receive, from a second node, a request to establish a session; perform, in response to the request, a network address translation (NAT) operation to establish the session, the NAT operation causing a first port block to be allocated to the session, the first port block including a first set of ports via which traffic, associated with the session, is transported; determine that the set of ports are no longer available for the session; determine whether a quantity of times that the first port block has been allocated to the session is greater than a threshold; and retain the first port block, for the session, when the quantity of times that the first port block has been allocated to the session is not greater than the threshold.