公开(公告)号：US20210215705A1

公开(公告)日：2021-07-15

申请号：US17214585

申请日：2021-03-26

Applicant: TSUTOMU TAKEUCHI ,  KEIKO YOSHIMOTO ,  KOWA COMPANY, LTD.

Inventor： Tsutomu Takeuchi ,  Keiko Yoshimoto

IPC: G01N33/68 ,  C07K14/705 ,  C07K16/24 ,  G01N33/74 ,  G01N33/564

Abstract: An antibody against a peptide having an amino acid sequence AVQGPEETVT QDC (expressed in single letter amino acid code) as represented by SEQ ID: NO. 1 corresponding to the 134- to 146-positions in human BAFF (B cell activating factor belonging to the TNF family) protein which is preferably a monoclonal antibody; a method of producing the above antibody; a medicinal composition containing the antibody; utilization of the antibody; and a method of screening an inhibitory effect or an activating effect on BAFF with the use of the antibody.

公开(公告)号：US08777296B2

公开(公告)日：2014-07-15

申请号：US13982058

申请日：2011-08-10

Applicant: Seiichi Suzuki ,  Tsutomu Takeuchi ,  Toshihiko Ishida

Inventor： Seiichi Suzuki ,  Tsutomu Takeuchi ,  Toshihiko Ishida

IPC: B60R3/02 ,  B60R3/00 ,  B60J5/06 ,  E05F15/14

CPC classification number: B60R3/002 ,  B60J5/06 ,  B60R3/00 ,  B62D25/025 ,  E05F15/632 ,  E05Y2900/531

Abstract: A step unit that guides a sliding door of a vehicle includes a step member and a rail plate member. The step member includes first and second lower rails. The first lower rail has two ends that face toward each other to form a cutout portion in between. The rail plate member is arranged in the cutout portion. The step member includes an insertion hole and an extended portion. The insertion hole is located at a position corresponding to the cutout portion. The extended portion is extended from at least one of the two ends to support the rail plate member against a load received by the rail plate member from the roller. The rail plate member is inserted through the insertion hole from above the upper side of the step member and fixed by a fastening member to the step member.

Abstract translation: 引导车辆的滑动门的踏板单元包括台阶构件和轨板构件。 台阶部件包括第一和第二下部导轨。 第一下导轨具有彼此面对的两个端部，以在其间形成切口部分。 轨板构件布置在切口部分中。 台阶构件包括插入孔和延伸部分。 插入孔位于与切口部对应的位置。 延伸部分从两个端部中的至少一个延伸，以支撑轨道板构件抵抗由轨道板构件从辊接收的负载。 轨板构件从台阶构件的上侧的上方穿过插入孔，并通过紧固构件固定到台阶构件。

公开(公告)号：US08622408B2

公开(公告)日：2014-01-07

申请号：US13510124

申请日：2010-11-17

Applicant: Toshihiko Ishida ,  Tsutomu Takeuchi ,  Shigeyuki Miyazaki ,  Shin Sakai ,  Seiichi Suzuki

Inventor： Toshihiko Ishida ,  Tsutomu Takeuchi ,  Shigeyuki Miyazaki ,  Shin Sakai ,  Seiichi Suzuki

IPC: E05F15/14

CPC classification number: B60R3/00 ,  B60J5/06 ,  E05F15/646 ,  E05Y2201/652 ,  E05Y2900/531

Abstract: A step unit comprises: a step member which is provided on the vehicle body side so as to be adjacent to a slide door of the vehicle and has a flat plate section on which an occupant's foot is placed; and a drive device which is affixed to the step member and drives the slide door to open and close the slide door. The step member is molded using a resin material and has a accommodation portion which is provided with a bottom formed below the upper surface of the flat plate section. The drive device is affixed while at least a part thereof is accommodated within the accommodation portion.

Abstract translation: 台阶单元包括：台阶构件，其设置在车身侧以与车辆的滑动门相邻并且具有放置乘客脚的平板部分; 以及驱动装置，其固定到台阶构件并驱动滑动门以打开和关闭滑动门。 台阶部件使用树脂材料成形，并具有设置有形成在平板部的上表面下方的底部的容纳部。 驱动装置固定在其至少一部分容纳在容纳部分内。

公开(公告)号：US20130307291A1

公开(公告)日：2013-11-21

申请号：US13982058

申请日：2011-08-10

Applicant: Seiichi Suzuki ,  Tsutomu Takeuchi ,  Toshihiko Ishida

Inventor： Seiichi Suzuki ,  Tsutomu Takeuchi ,  Toshihiko Ishida

IPC: B62D25/02

CPC classification number: B60R3/002 ,  B60J5/06 ,  B60R3/00 ,  B62D25/025 ,  E05F15/632 ,  E05Y2900/531

Abstract: A step unit that guides a sliding door of a vehicle includes a step member and a rail plate member. The step member includes first and second lower rails. The first lower rail has two ends that face toward each other to form a cutout portion in between. The rail plate member is arranged in the cutout portion. The step member includes an insertion hole and an extended portion. The insertion hole is located at a position corresponding to the cutout portion. The extended portion is extended from at least one of the two ends to support the rail plate member against a load received by the rail plate member from the roller. The rail plate member is inserted through the insertion hole from above the upper side of the step member and fixed by a fastening member to the step member.

Abstract translation: 引导车辆的滑动门的踏板单元包括台阶构件和轨板构件。 台阶部件包括第一和第二下部导轨。 第一下导轨具有彼此面对的两个端部，以在其间形成切口部分。 轨板构件布置在切口部分中。 台阶构件包括插入孔和延伸部分。 插入孔位于与切口部对应的位置。 延伸部分从两个端部中的至少一个延伸，以支撑轨道板构件抵抗由轨道板构件从辊接收的负载。 轨板构件从台阶构件的上侧的上方穿过插入孔，并通过紧固构件固定到台阶构件。

公开(公告)号：US08413379B2

公开(公告)日：2013-04-09

申请号：US13510146

申请日：2010-11-17

Applicant: Toshihiko Ishida ,  Tsutomu Takeuchi

Inventor： Toshihiko Ishida ,  Tsutomu Takeuchi

IPC: B60J5/06

CPC classification number: B60R3/02 ,  E05D15/0652 ,  E05F15/643 ,  E05Y2201/10 ,  E05Y2201/434 ,  E05Y2201/652 ,  E05Y2201/684 ,  E05Y2800/205 ,  E05Y2900/531

Abstract: A step unit includes: a step member which is provided with a pair of lower rails extending in an opening and closing direction of a slide door of the vehicle; and a rail plate member which is provided to a cutout formed in a part of either of the lower rails and which continuously connects the lower rails in the opening and closing direction. The step member is molded using a resin material and is provided with an insertion hole which vertically penetrates through the step member at a position corresponding to the cutout; and a support extension section which is extended from a side end of the cutout of the lower rail. The rail plate member is mounted to the step member by being inserted so as to penetrate through the insertion hole from above the step member.

Abstract translation: 台阶单元包括：台阶构件，其设置有沿车辆的滑动门的开闭方向延伸的一对下轨道; 以及轨道板构件，其设置在形成在任一个下轨道的一部分中的切口，并且沿开闭方向连续地连接下轨道。 台阶部件使用树脂材料成形，并且在与切口对应的位置处设置有垂直地穿过台阶部件的插入孔; 以及从下轨道的切口的侧端延伸的支撑延伸部。 轨板构件通过插入从而从台阶构件的上方穿过插入孔安装到台阶构件。

公开(公告)号：US08217543B2

公开(公告)日：2012-07-10

申请号：US12671852

申请日：2008-10-15

Applicant: Toshihiko Ishida ,  Tsutomu Takeuchi ,  Naoya Oku

Inventor： Toshihiko Ishida ,  Tsutomu Takeuchi ,  Naoya Oku

IPC: H02K7/10

CPC classification number: F16D27/06 ,  E05F15/611 ,  E05Y2201/216 ,  E05Y2201/246 ,  E05Y2201/462 ,  E05Y2900/531 ,  H02K5/141 ,  H02K7/1085 ,  H02K7/1166

Abstract: An electromagnetic clutch includes a motor, a worm wheel rotatably driven by a motor, a rotor having an electromagnetic coil and rotatable about a same rotational axis as the worm wheel, an armature that is mounted to the worm wheel and is pulled into contact with the rotor upon application of electric power to the electromagnetic coil, so that the armature is rotated with the rotor, a cover member configured to cover the rotor and the armature, and a power supply mechanism disposed between the cover member and the rotor and connected to a power source for supplying power to the electromagnetic coil. The power supply mechanism includes a fixed frame body having a first power supply portion for receiving the power from the power source and fixed to the cover member, a rotary frame body having a second power supply portion in contact with the first power supply portion for supplying the power to the electromagnetic coil, the rotary frame body being fixed to the rotor and rotatably engaged with the fixed frame body; and a plate-like conducting member provided in the cover member, the conducting member coming into contact with a portion of the first power supply portion projecting from the fixed frame body.

Abstract translation: 电磁离合器包括电动机，由电动机可旋转地驱动的蜗轮，具有电磁线圈并且可绕与蜗轮相同的旋转轴线旋转的转子，安装到蜗轮并与其接触的电枢 在电磁线圈施加电力时使电枢转动，盖构件覆盖转子和电枢的盖构件以及设置在盖构件和转子之间并连接到电枢的电源机构 用于向电磁线圈供电的电源。 电源机构包括：固定框体，具有用于从电源接收电力并固定到盖构件的第一电源部;具有与第一电源部接触的第二电源部的旋转框架体，供给部 电磁线圈的动力，旋转框架体固定在转子上并与固定框架体旋转接合; 以及设置在所述盖构件中的板状导电构件，所述导电构件与从所述固定框架体突出的所述第一电力供应部的一部分接触。

公开(公告)号：US07980633B2

公开(公告)日：2011-07-19

申请号：US11605364

申请日：2006-11-29

Applicant: Mitsue Koyano ,  Tsutomu Takeuchi ,  Takeshi Ohara ,  Takashi Sunaga

Inventor： Mitsue Koyano ,  Tsutomu Takeuchi ,  Takeshi Ohara ,  Takashi Sunaga

IPC: A47C7/02

CPC classification number: B62J1/12

Abstract: A seat for a vehicle and a seat for a watercraft include a polyurethane-made first cushion body covered with a seat skin. A thermoplastic elastomer-made second cushion body is disposed between the first cushion body and a bottom plate 43. The relationships of t1

Abstract translation: 用于车辆的座椅和用于船只的座椅包括覆盖有座椅皮肤的聚氨酯制成的第一缓冲体。 在第一缓冲体和底板43之间设置热塑弹性体制成的第二缓冲体。建立t1

公开(公告)号：US07846662B2

公开(公告)日：2010-12-07

申请号：US11662795

申请日：2005-09-14

Applicant: Tsutomu Takeuchi ,  Kensei Tsuzuka ,  Keiko Yoshimoto

Inventor： Tsutomu Takeuchi ,  Kensei Tsuzuka ,  Keiko Yoshimoto

IPC: C12Q1/68

CPC classification number: C07K16/2875 ,  A61K31/341 ,  G01N33/5008 ,  G01N33/5023 ,  G01N33/505 ,  G01N33/5052 ,  G01N33/6863 ,  G01N2500/00

Abstract: A method of screening a novel BAFF suppressor or inhibitor. More specifically speaking, a method which comprises adding a combination of TPA with ionomycin and/or an anti-CD3 antibody to a cultured human cell to thereby induce the production of BAFF by the cell; a method of screening a substance capable of suppressing the expression or activity of BAFF which comprises adding a test substance to a BAFF-production system prepared by adding a combination of TPA with ionomycin and/or an anti-CD3 antibody to a cultured human cell and measuring the expression amount and/or the activity of BAFF in the BAFF-production system; and a BAFF production inducer for a BAFF-producing cell which contains a combination of TPA with ionomycin and/or an anti-CD3 antibody.

Abstract translation: 筛选新型BAFF抑制剂或抑制剂的方法。 更具体地说，包括将TPA与离子霉素和/或抗CD3抗体的组合加入到培养的人细胞中，从而诱导细胞产生BAFF的方法; 筛选能够抑制BAFF的表达或活性的物质的方法，其包括向经培养的人细胞添加TPA与离子霉素和/或抗CD3抗体的组合而制备的BAFF-生产系统中的测试物质，以及 测量BAFF在BAFF生产系统中的表达量和/或活性; 以及含有TPA与离子霉素和/或抗CD3抗体的组合的BAFF产生细胞的BAFF产生诱导剂。

公开(公告)号：US07562734B2

公开(公告)日：2009-07-21

申请号：US10969296

申请日：2004-10-06

Applicant: Kengo Yano ,  Fuminori Kamemizu ,  Sadamichi Enjo ,  Junji Kikuno ,  Tsutomu Takeuchi

Inventor： Kengo Yano ,  Fuminori Kamemizu ,  Sadamichi Enjo ,  Junji Kikuno ,  Tsutomu Takeuchi

IPC: B62D61/02 ,  B62J9/00

CPC classification number: B62K19/46 ,  B62K2202/00

Abstract: The present invention relates to a luggage storage device for a motorcycle. In an embodiment, the invention can allow the capacity of a storage box to be large enough to accommodate long goods therein. In an embodiment, the invention includes a storage box having a front helmet storage portion and a rear helmet storage portion. The front helmet storage portion is disposed under a front seat. The rear helmet storage portion is disposed under a rear seat, which together with the front seat, constitutes a tandem type riding seat. The storage box is disposed under the riding seat so as to extend from under a front end of the riding seat up to near an upper portion of a rear cushion that suspends a rear wheel from a rear portion of a vehicle body frame.

Abstract translation: 本发明涉及一种用于摩托车的行李储存装置。 在一个实施例中，本发明可以允许存储箱的容量足够大以容纳其中的长货物。 在一个实施例中，本发明包括具有前头盔存放部分和后头盔存放部分的储物箱。 前头盔存放部设置在前排座椅的下方。 后头盔存放部配置在与前排座椅一起构成串联式座椅的后座椅的下方。 存放箱被设置在乘坐座下方，以便从乘坐座椅的前端向下延伸到从车体框架的后部悬挂后轮的后缓冲垫的上部附近。

公开(公告)号：US20080305502A1

公开(公告)日：2008-12-11

申请号：US11662795

申请日：2005-09-14

Applicant: Tsutomu Takeuchi ,  Kensei Tsuzaka ,  Keiko Yoshimoto

Inventor： Tsutomu Takeuchi ,  Kensei Tsuzaka ,  Keiko Yoshimoto

IPC: G01N33/574 ,  C12P21/04 ,  G01N33/573 ,  C12N9/50 ,  C07K16/18

CPC classification number: C07K16/2875 ,  A61K31/341 ,  G01N33/5008 ,  G01N33/5023 ,  G01N33/505 ,  G01N33/5052 ,  G01N33/6863 ,  G01N2500/00

Abstract: A method of screening a novel BAFF suppressor or inhibitor. More specifically speaking, a method which comprises adding a combination of TPA with ionomycin and/or an anti-CD3 antibody to a cultured human cell to thereby induce the production of BAFF by the cell; a method of screening a substance capable of suppressing the expression or activity of BAFF which comprises adding a test substance to a BAFF-production system prepared by adding a combination of TPA with ionomycin and/or an anti-CD3 antibody to a cultured human cell and measuring the expression amount and/or the activity of BAFF in the BAFF-production system; and a BAFF production inducer for a BAFF-producing cell which contains a combination of TPA with ionomycin and/or an anti-CD3 antibody.

Abstract translation: 筛选新型BAFF抑制剂或抑制剂的方法。 更具体地说，包括将TPA与离子霉素和/或抗CD3抗体的组合加入到培养的人细胞中，从而诱导细胞产生BAFF的方法; 筛选能够抑制BAFF的表达或活性的物质的方法，其包括向经培养的人细胞添加TPA与离子霉素和/或抗CD3抗体的组合而制备的BAFF-生产系统中的测试物质，以及 测量BAFF在BAFF生产系统中的表达量和/或活性; 以及含有TPA与离子霉素和/或抗CD3抗体的组合的BAFF产生细胞的BAFF产生诱导剂。