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    COMPOSITION AND A METHOD FOR PRODUCING CONTRAST AGENT USING THE COMPOSITION
    2.
    发明申请
    COMPOSITION AND A METHOD FOR PRODUCING CONTRAST AGENT USING THE COMPOSITION 审中-公开
    组合物和使用该组合物生产对比剂的方法

    公开(公告)号：US20120052011A1

    公开(公告)日：2012-03-01

    申请号：US13205246

    申请日：2011-08-08

    申请人： Tatsuki Fukui ,  Satoshi Yuasa ,  Kouichi Kato

    发明人： Tatsuki Fukui ,  Satoshi Yuasa ,  Kouichi Kato

    IPC分类号： A61K49/00 ,  A61P43/00

    CPC分类号： A61K49/0034 ,  A61K49/0032

    摘要： A composition including a hydrophilic dye having a sulfonate group and a hydrophobic solvent, wherein the composition includes at least one of a nicotinic acid derivative and a tiamine derivative, can form densely accumulated particles and the like since the composition includes a hydrophilic dye that is likely to dissolve in a hydrophobic solvent.

    摘要翻译： 包含具有磺酸盐基团和疏水性溶剂的亲水性染料的组合物，其中所述组合物包含烟酸衍生物和硫胺素衍生物中的至少一种可以形成致密聚集的颗粒等，因为该组合物包含可能的亲水性染料 溶解在疏水性溶剂中。

    CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME
    3.
    发明申请
    CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING AND PHOTOACOUSTIC IMAGING METHOD USING THE SAME 审中-公开
    用于摄影成像的对比剂和使用其的光电成像方法

    公开(公告)号：US20120027679A1

    公开(公告)日：2012-02-02

    申请号：US13112135

    申请日：2011-05-20

    申请人： Fumio Yamauchi ,  Satoshi Ogawa ,  Kengo Kanazaki ,  Sachiko Inoue ,  Tatsuki Fukui ,  Masato Minami ,  Mayuko Kishi

    发明人： Fumio Yamauchi ,  Satoshi Ogawa ,  Kengo Kanazaki ,  Sachiko Inoue ,  Tatsuki Fukui ,  Masato Minami ,  Mayuko Kishi

    IPC分类号： A61K49/00 ,  B32B5/16 ,  C07K17/14 ,  G01N33/574 ,  B82Y15/00

    CPC分类号： A61K49/221 ,  A61K41/00 ,  A61K47/6855 ,  A61K49/225 ,  A61K49/226 ,  G01N33/53 ,  Y10T428/2982 ,  Y10T428/2989

    摘要： It is intended to provide a novel contrast agent for photoacoustic imaging that is highly capable of binding to a target molecule and generates high photoacoustic signals. The present invention provides a contrast agent for photoacoustic imaging represented by Formula 1: MNP−((L)l−(P)m)n   (Formula 1) (wherein MNP represents a particle containing an iron oxide particle; L represents a linker molecule; P represents a ligand molecule; l represents 0 or 1; and m and n represent an integer of 1 or larger), the contrast agent for photoacoustic imaging including: a particle containing an iron oxide particle that absorbs light in a near-infrared region; and at least one or more ligand molecule(s) immobilized on the particle containing an iron oxide particle, wherein the immobilization density of the ligand molecule is equal to or higher than the cell surface density of a target molecule.

    摘要翻译： 旨在提供一种新颖的光声成像造影剂，其具有高度能够结合靶分子并产生高光声信号。 本发明提供了由式1表示的光声成像造影剂：MNP - （（L）1-（P）m）n（式1）（其中，MNP表示含有氧化铁颗粒的颗粒; L表示连接分子 ; P表示配体分子; l表示0或1; m和n表示1或更大的整数），光声成像用造影剂包括：含有吸收近红外区域的光的氧化铁粒子的粒子 ; 和固定在含有氧化铁颗粒的颗粒上的至少一种或多种配体分子，其中配体分子的固定密度等于或高于靶分子的细胞表面密度。

    Novel polyhydroxyalkanoate having amide, sulfonic acid or sulfonate ester group, charge control agent and toner
    6.
    发明申请
    Novel polyhydroxyalkanoate having amide, sulfonic acid or sulfonate ester group, charge control agent and toner 失效
    具有酰胺，磺酸或磺酸酯基的新型聚羟基链烷酸酯，电荷控制剂和调色剂

    公开(公告)号：US20060287473A1

    公开(公告)日：2006-12-21

    申请号：US11172662

    申请日：2005-06-24

    申请人： Tatsuki Fukui ,  Tetsuya Yano ,  Chieko Mihara ,  Shinya Kozaki ,  Tsutomu Honma ,  Takashi Kenmoku ,  Ako Kusakari

    发明人： Tatsuki Fukui ,  Tetsuya Yano ,  Chieko Mihara ,  Shinya Kozaki ,  Tsutomu Honma ,  Takashi Kenmoku ,  Ako Kusakari

    IPC分类号： C08G63/02

    CPC分类号： C08G63/912 ,  C08G63/6852 ,  C08G63/6882 ,  G03G9/08755 ,  G03G9/08791

    摘要： The invention provides a novel polyester adapted for use in a charge control agent for a toner for an electrophotographic process, having a charge stability, a high charge amount, an improved dispersibility and a biodegradability, and a producing method and an application technology therefor. According to the invention, there is provided polyhydroxyalkanoate comprising at least one unit represented by the following chemical formula in a molecule: —(O—CH(—(CH2)m—CH2-p-C6H4—CONH-A1SO2R1)CH2CO)— (wherein R1 represents OH, a halogen atom, ONa, OK or OR1a; A1 and R1a each represents a substituted or unsubstituted aliphatic hydrocarbon structure, a substituted or unsubstituted aromatic cyclic structure or a substituted or unsubstituted heterocyclic structure; m represents an integer selected from a range of 0 to 7; and R1, A1, R1a and m have the aforementioned meanings independently for each unit when plural units are present), a charge control agent containing such polyhydroxyalkanoate, a toner utilizing such charge control agent, and an image forming method and an image forming apparatus utilizing such toner.

    摘要翻译： 本发明提供一种适用于电荷控制剂用电荷控制剂的新型聚酯，其具有电荷稳定性，高电荷量，改进的分散性和生物降解性，以及其制备方法和应用技术。 根据本发明，提供了在分子中包含由以下化学式表示的至少一个单元的聚羟基链烷酸酯：<？in-line-formula description =“In-line Formulas”end =“lead”→> - （O- CH（ - （CH 2 CH 2）m CH 2 CH 2 CH 2 CH 2 CH 2 - -CONH-A 1 2 1 CO 2） （其中R 1表示OH，卤素原子，ONa，OK或OR 1a; A < 取代或未取代的脂族烃结构，取代或未取代的芳族环状结构或取代或未取代的杂环结构; m表示选自以下的整数; R 1，R 2， 0至7;当存在多个单元时，R 1，A 1，R 1a和m对于每个单元具有上述含义 ），含有这种聚羟基链烷酸酯的电荷控制剂 e，使用这种电荷控制剂的调色剂，以及使用这种调色剂的图像形成方法和图像形成装置。

    Novel polyhydroxy alkanoate copolymer including within molecule unit having vinyl group or carboxyl group in side chain, and producing method therefor
    7.
    发明申请
    Novel polyhydroxy alkanoate copolymer including within molecule unit having vinyl group or carboxyl group in side chain, and producing method therefor 有权
    在侧链中具有乙烯基或羧基的分子单元内的新型多羟基链烷酸酯共聚物及其制造方法

    公开(公告)号：US20060211100A1

    公开(公告)日：2006-09-21

    申请号：US10531689

    申请日：2003-10-23

    申请人： Takashi Kenmoku ,  Tetsuya Yano ,  Chieko Mihara ,  Shinya Kozaki ,  Tsutomu Honma ,  Tatsuki Fukui ,  Takeshi Imamura ,  Etsuko Sugawa

    发明人： Takashi Kenmoku ,  Tetsuya Yano ,  Chieko Mihara ,  Shinya Kozaki ,  Tsutomu Honma ,  Tatsuki Fukui ,  Takeshi Imamura ,  Etsuko Sugawa

    IPC分类号： C12P7/62 ,  C08G63/87

    CPC分类号： C08G63/06 ,  C08G63/6882 ,  C12P7/625

    摘要： The invention provides a PHA copolymer including at least a 3-hydroxy-ω-carboxyalkanoic acid represented by a formula (19) or (32) and simultaneously at least a unit represented by a formula (2) or a formula (3) in a molecule, a precursor PHA copolymer having a corresponding vinyl group or a corresponding alkoxycarbonyl group, a biosynthesis method thereof by microorganisms, and a method of producing a desired PHA copolymer from the precursor PHA copolymer: (wherein k, m, n are integers; R18 represents H, Na, K, R27? represents (A); R1 represents a substituent on a cyclohexyl group and represents H, CN, NO2, a halogen atom, CH3, C2H5, C3H7, CF3, C2F5, or C3F7; R includes a residue including a phenyl structure or a thienyl structure; these being independent for each unit).

    摘要翻译： 本发明提供一种PHA共聚物，其包含至少一种由式（19）或（32）表示的3-羟基-ω-羧基烷酸，同时至少由式（2）或式（3）表示的单元在 分子，具有相应的乙烯基或相应的烷氧基羰基的前体PHA共聚物，微生物的生物合成方法以及由前体PHA共聚物制备所需PHA共聚物的方法（其中k，m，n为整数; R 表示H，Na，K，R “custom 27？表示（A）; R 1表示环己基上的取代基，代表H，CN ，NO 2 2，卤素原子，CH 3，C 2 H 5，C 3， H 3，CF 3，C 2 H 5，或C 3 H 3， R> R包括残基 e包括苯基结构或噻吩基结构; 这些对于每个单元是独立的）。

    Method for controlling molecular weight of polyhydroxyalkanote constituted on units containing residue of pheynyl-, thienyl-, or cyclohexyl-structure in side chain of molecule
    8.
    发明授权
    Method for controlling molecular weight of polyhydroxyalkanote constituted on units containing residue of pheynyl-, thienyl-, or cyclohexyl-structure in side chain of molecule 失效
    用于控制分子量分子量的方法，由含有分子侧链中苯基，噻吩基或环己基结构残基的单元构成

    公开(公告)号：US06649380B1

    公开(公告)日：2003-11-18

    申请号：US10373038

    申请日：2003-02-26

    申请人： Tetsuya Yano ,  Takashi Kenmoku ,  Tsutomu Honma ,  Etsuko Sugawa ,  Tatsuki Fukui ,  Takeshi Imamura

    发明人： Tetsuya Yano ,  Takashi Kenmoku ,  Tsutomu Honma ,  Etsuko Sugawa ,  Tatsuki Fukui ,  Takeshi Imamura

    IPC分类号： C12P762

    CPC分类号： C12P7/625 ,  C08G63/06 ,  C08G63/6882 ,  Y10S435/874

    摘要： A method is provided for controlling the molecular weight of a polyhydroxyalkanoate containing at least one of a unit: —[OCH((CH2)mR1)CH2C(O)]— (m=1-8; R1 is a residue having a ring structure of any of phenyl and thienyl structure), and a unit: —[OCH((CH2)kC6H1)R2)CH2C(O)]— (k=0-8; R2 denotes a substituent on the cyclohexyl group including H, CN, NO2, halogen atom, CH3, C2H5, C3H7, CF3, C2F5 or C3F7), wherein a microorganism is cultivated in the presence of a hydroxyl group-containing compound, which is capable of producing the polyhydroxyalkanoate from R3(CH2)qCH2CH2COOH (q=1-8; R3 contains a residue having a ring structure of phenyl or thienyl) or R4C6H10(CH2)rCH2CH2COOH (r=0-8; R4 denotes a substituent on the cyclohexyl group including H, CN, NO2, halogen, CH3, C2H5, C3H7, CF3, C2F5, or C3F7).

    摘要翻译： 提供一种控制含有至少一个单元的聚羟基链烷酸酯的分子量的方法： - [OCH（（CH 2）m R 1）CH 2 C（O）] - （m = 1-8; R 1是具有环结构 苯基和噻吩基结构中的任一个取代基）和单位： - [OCH（（CH 2）k C 6 H 1）R 2）CH 2 C（O）] - （k = 0-8; R 2表示环己基上的取代基， NO 2，卤素原子，CH 3，C 2 H 5，C 3 H 7，CF 3，C 2 F 5或C 3 F 7），其中微生物在含羟基化合物存在下培养，其能够由R3（CH2）qCH2CH2COOH（q = 1-8; R3包含具有苯基或噻吩基的环结构的残基）或R4C6H10（CH2）rCH2CH2COOH（r = 0-8; R4表示环己基上的取代基，包括H，CN，NO2，卤素，CH3，C2H5 ，C3H7，CF3，C2F5或C3F7）。