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    CONTROLLED RELEASE OF COMPOUNDS
    3.
    发明申请
    CONTROLLED RELEASE OF COMPOUNDS 有权

    公开(公告)号：US20230035578A1

    公开(公告)日：2023-02-02

    申请号：US17757536

    申请日：2020-12-18

    申请人： TECHNISCHE UNIVERSITAET MUENCHEN

    发明人： Oliver LIELEG ,  Ceren KIMNA ,  Benjamin WINKELJANN

    IPC分类号： A61L27/34 ,  A61L27/54 ,  A61L29/08 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16

    摘要： The present invention relates to a method for preparation of a functionalized surface comprising the steps: a) coating of a carrier with a least one polymer selected from a polyanionic or polycationic polymer, b) addition of at least one compound to the coated carrier of step a), c) exposing the at least one polyanionic or polycationic polymer on the coated carrier of step b) to an organic solvent, resulting in compaction of the at least one polyanionic or polycationic polymer and thereby encapsulating the at least one compound, d) reversible cross-linking of the at least one polyanionic or polycationic polymer of step c) with at least one cross-linker; e) removal of the organic solvent. Furthermore, the invention relates to a functionalized surface, a functionalized surface for use in medicine and a method for releasing a compound ex vivo.

    Mutant beta-glucosidase variants with increased thermostability
    5.
    发明授权
    Mutant beta-glucosidase variants with increased thermostability 有权

    公开(公告)号：US10907140B2

    公开(公告)日：2021-02-02

    申请号：US15767066

    申请日：2016-09-05

    申请人： Technische Universitaet Muenchen

    发明人： Vladimir Zverlov ,  Wolfgang Schwarz ,  Roman Prechtl ,  Benedikt Leis ,  Claudia Held ,  Wolfgang Liebl

    IPC分类号： C12N9/42 ,  C12N15/86 ,  C12P19/14

    摘要： A mutant β-glucosidase polypeptide exhibits enhanced thermostability and has the amino acid sequence: MAKFPRDFVWGTATSSYQIEGAVNEDGRTPSIWDTFSKTX1GKTYKGHT GDVACDHYHRYKEDVEILKEIGVKAYRFSIAWPRIFPEEGKYNPKGMDF YKKLIDELQKRDIX2PAATIYHWDLPQWAYDKGGGWLNRESIKWYVEYA TKLFEELGDAIPLWITHNEPWCSSILSYGIGEHAPGHKNYREALIAAHH ILLSHGEAVKAFREMNIKGSKIGITLNLTPAYPASEKEEDKLAAQYADG FANRWELDPIFKGNYPEDMMELYSKIIGEFDFIKEGDLETISVPIDFLG X3NYYTRSIVKYDEDSMLKAENVPGPGKRTEMGWEISPESLYDLLKRLD REYTKLPMYITENGAAFKDEVTEDGRVHDDERIEYIKEHLKAAAKFIGE GGNLKGYFVWSLMDNFEWAHGYSKRFGIVYVDYX4TQKRILKDSALWYK EVIX5DDGIED, wherein X1 is selected from E, P, T, M, A, S and G; X2 is selected from V, K, R and H; X3 is selected from I, L, M, P, T and A; X4 is selected from T, E, D, N, Q, M and P; and X5 is selected from L, R, K and H.

    CRETION-COMPETENT MUTEINS OF THE HUMAN IL-27 ALPHA-SUBUNIT
    6.
    发明申请
    CRETION-COMPETENT MUTEINS OF THE HUMAN IL-27 ALPHA-SUBUNIT 审中-公开

    公开(公告)号：US20200062817A1

    公开(公告)日：2020-02-27

    申请号：US16609726

    申请日：2018-05-04

    申请人： TECHNISCHE UNIVERSITAET MUENCHEN

    发明人： Matthias FEIGE ,  Stephanie MUELLER

    IPC分类号： C07K14/54 ,  A61P37/06

    摘要： The present invention refers to a secretion-competent mutein of the α-subunit of human Interleukin 27 and to a human heterodimeric Interleukin 27. The present invention further refers to a nucleic acid molecule comprising a nucleotide sequence encoding a secretion-competent mutein of the α-subunit of human Interleukin 27 or the human heterodimeric Interleukin 27, to a host cell containing a nucleic acid molecule comprising a nucleotide sequence encoding a secretion-competent mutein of the α-subunit of human Interleukin 27 or of the human heterodimeric Interleukin 27. The invention also refers to an immune modulator comprising a secretion-competent mutein of the α-subunit of human Interleukin 27 or of the human heterodimeric Interleukin 27, to the respective use thereof as well as to a method of producing said secretion-competent muteins and to a secretion-incompetent mutein of the α-subunit of mouse Interleukin 27 and a secretion-competent mutein of the β-subunit of mouse Interleukin 27.

    DEPTH SUPER-RESOLUTION FROM SHADING
    7.
    发明申请
    DEPTH SUPER-RESOLUTION FROM SHADING 审中-公开

    公开(公告)号：US20190340729A1

    公开(公告)日：2019-11-07

    申请号：US16400584

    申请日：2019-05-01

    申请人： Technische Universitaet Muenchen

    发明人： Bjoern HAEFNER ,  Yvain Quéau ,  Thomas Moellenhoff ,  Daniel Cremers

    IPC分类号： G06T3/40 ,  G06T5/50 ,  G06T7/507 ,  G06T7/10

    摘要： A method for determining a high-resolution depth map of a scene, the method comprising: obtaining a low-resolution depth map of the scene, obtaining a high-resolution image of the scene, initializing an estimated reflectance map, an estimated lighting vector and an estimated depth map, wherein the estimated depth map is in high-resolution, iteratively simultaneously updating the estimated reflectance map, the estimated lighting vector, and the estimated depth-map, wherein updating the estimated depth map is partially based on the high-resolution image, and determining the high-resolution depth map based on the iteratively updated estimated depth-map.

    ELECTRONIC AMPLIFIER FOR AMPLIFYING AN INPUT SIGNAL
    8.
    发明申请
    ELECTRONIC AMPLIFIER FOR AMPLIFYING AN INPUT SIGNAL 审中-公开

    公开(公告)号：US20190173375A1

    公开(公告)日：2019-06-06

    申请号：US16266723

    申请日：2019-02-04

    申请人： TECHNISCHE UNIVERSITAET MUENCHEN

    发明人： BERNHARD LEHMEYER ,  AMINE MEZGHANI ,  JOSEF NOSSEK

    IPC分类号： H02M1/34 ,  H02M1/088 ,  H02M7/537 ,  H03F3/217

    CPC分类号： H02M1/34 ,  H02M1/088 ,  H02M7/537 ,  H03F3/2171 ,  H03F3/2173

    摘要： An electronic amplifier for amplifying an input signal has a branching node, a supply branch, a balance branch, an auxiliary branch and a load branch. All of the branches are connected in parallel to each other relative to the branching node and a reference potential. The supply branch supplies a DC voltage to the branching node. The balance branch absorbs and/or storing electric energy. A current supply device supplies a DC current. The control switch, the current valve and the current source are in different branches. The control switch, in a pass current state, establishes a current flow from the supply branch into either the auxiliary branch or the balance branch. In the block current state, current flows from the current supply device to the balancing device. The supply, balance and auxiliary branches provide an amplified signal to the load, controlled only by the input signal at the control switch.

    METHOD FOR DEMODULATION AND DEMODULATOR
    9.
    发明申请
    METHOD FOR DEMODULATION AND DEMODULATOR 有权
    解调和解调器的方法

    公开(公告)号：US20170078134A1

    公开(公告)日：2017-03-16

    申请号：US15361766

    申请日：2016-11-28

    申请人： TECHNISCHE UNIVERSITAET MUENCHEN

    发明人： Josef A. NOSSEK ,  Manuel STEIN ,  Sebastian THEILER

    IPC分类号： H04L27/38 ,  H04B17/20 ,  H04B1/00 ,  H04B1/06

    CPC分类号： H04L27/38 ,  H04B1/0017 ,  H04B1/06 ,  H04B17/20

    摘要： A method is provided for demodulation of an analog receive signal carrying information, wherein a number of more than two analog signals is formed from the receive signal in separate channels such that the receive signal is multiplied in each case by a period function, the phase thereof respectively differing in the channels, and wherein the multiple signals are each low-pass filtered.

    摘要翻译： 提供了一种用于解调携带信息的模拟接收信号的方法，其中在单独信道中从接收信号形成多于两个的模拟信号的数量，使得接收信号在每种情况下被乘以周期函数，其相位 分别在通道中不同，并且其中多个信号各自被低通滤波。

    METHOD AND SYSTEM FOR AUTOMATIC DISTRIBUTION AND SOLUTION OF TASKS
    10.
    发明申请
    METHOD AND SYSTEM FOR AUTOMATIC DISTRIBUTION AND SOLUTION OF TASKS 审中-公开
    方法和系统的自动分配和解决方案的任务

    公开(公告)号：US20160236077A1

    公开(公告)日：2016-08-18

    申请号：US14624407

    申请日：2015-02-17

    申请人： Technische Universitaet Muenchen

    发明人： Maximilian Baust ,  Christoph Hennersperger ,  Nassir Navab

    IPC分类号： A63F13/23 ,  A63F13/52 ,  A63F13/31 ,  H04L29/06

    CPC分类号： A63F13/23 ,  A63F13/31 ,  A63F13/52 ,  G06F9/5027 ,  H04L67/38

    摘要： A method for distributing tasks includes selecting at least one interactive process according to at least one task and transferring input data related to the at least one task to at least one server associated with the at least one interactive process. The input data is to be distributed to one or more clients configured to execute entities of the at least one interactive process. The method further includes collecting, from the at least one server associated with the at least one interactive process, one or more results of processing of respective entities of the at least one interactive process based on the input data on the one or more clients, and providing output data for the at least one task based on the collected one or more results.

    摘要翻译： 一种用于分发任务的方法包括根据至少一个任务选择至少一个交互过程，并将与至少一个任务有关的输入数据传送给与至少一个交互过程相关联的至少一个服务器。 输入数据将被分配给被配置为执行至少一个交互过程的实体的一个或多个客户端。 该方法还包括从至少一个与至少一个交互过程相关联的服务器中收集基于一个或多个客户端上的输入数据的至少一个交互过程的相应实体的一个或多个处理结果，以及 基于所收集的一个或多个结果为所述至少一个任务提供输出数据。