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    Fiber array for optical imaging and therapeutics
    1.
    发明授权
    Fiber array for optical imaging and therapeutics 有权
    用于光学成像和治疗的光纤阵列

    公开(公告)号：US08798722B2

    公开(公告)日：2014-08-05

    申请号：US13203800

    申请日：2010-03-01

    申请人： Christopher Rylander ,  Thomas A. Campbell ,  Ge Wang ,  Yong Xu ,  Mehmet Alpaslan Kosoglu

    发明人： Christopher Rylander ,  Thomas A. Campbell ,  Ge Wang ,  Yong Xu ,  Mehmet Alpaslan Kosoglu

    IPC分类号： A61B5/00

    CPC分类号： A61B18/203 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/411 ,  A61B5/442 ,  A61B5/444 ,  A61B5/685 ,  A61B2018/00452 ,  A61N5/0616 ,  A61N2005/0631 ,  A61N2005/067 ,  G02B6/032 ,  G02B6/06 ,  G02B6/262

    摘要： The present invention relates to the field of optical imaging and therapeutics. More particularly, embodiments of the present invention provide minimally-invasive Fiberoptic Microneedle Devices (FMDs) for light-based therapeutics, which physically penetrate tissue and deliver light directly into the target area below the skin surface (FIG. 1). A preferred embodiment of the invention is a fiberoptic microneedle device comprising: (a) one or more silica-based needles capable of guiding light and comprising a length of about 0.5-6 mm, a base having an outer diameter in the range of about 100-150 micron, and a tip having an outer diameter in the range of about 5-20 micron; (b) a support member to which the needles are secured; (c) a ferrule comprising one or more holes for each of the needles, wherein the ferrule is operably configured to provide mechanical support to each needle at all or some portion of the length of the needle. Embodiments of the invention enable depth-selective and deep photothermal therapeutics and can be adapted for use with any laser-based treatment or diagnostic in which light is used to detect or treat targets under or on the skin surface.

    摘要翻译： 本发明涉及光学成像和治疗学领域。 更具体地说，本发明的实施例提供了用于基于光的治疗剂的微创光纤微针装置（FMD），其物理地穿透组织并将光直接传送到皮肤表面下方的目标区域（图1）。 本发明的优选实施例是一种光纤微针装置，包括：（a）一个或多个能够引导光并且包括约0.5-6mm的长度的基于二氧化硅的针，具有约100的外径的基部 -150微米，以及外径在约5-20微米范围内的尖端; （b）固定针的支撑构件; （c）套圈，其包括用于每个针的一个或多个孔，其中所述套圈可操作地构造成在所述针的所述长度的全部或某一部分处为每个针提供机械支撑。 本发明的实施方案可实现深度选择性和深度光热治疗剂，并且可适用于任何基于激光的治疗或诊断，其中光用于检测或治疗皮肤表面下或皮肤表面上的靶标。

    Carbon nanotube nanometrology system
    3.
    发明授权
    Carbon nanotube nanometrology system 失效
    碳纳米管纳米体系

    公开(公告)号：US07564549B2

    公开(公告)日：2009-07-21

    申请号：US11745779

    申请日：2007-05-08

    申请人： Thomas A. Campbell ,  Kent D. Henry

    发明人： Thomas A. Campbell ,  Kent D. Henry

    IPC分类号： G01J3/44

    CPC分类号： B82Y40/00 ,  B82Y30/00 ,  C01B32/152 ,  C01B32/17 ,  C01B32/172 ,  C01B2202/02 ,  G01J3/1804 ,  G01J3/36 ,  G01J3/44 ,  G01J5/34 ,  G01N21/65

    摘要： The present invention provides systems and methods for quantifying, purifying and separating fullerenes, such as single wall carbon nanotubes (SWNTs). The purification/separation combination provides nearly 100% carbonaceous impurity-free SWNT content from a given impure sample and provides a desired chirality and diameter from a given non-separated sample. Nanometrological validation of the success of purification and separation uses a pyroelectric detector and Raman spectroscopy in a single system, thus providing a critical aspect for the nanomanufacturing environment. The purification/separation and nanometrological validations may be performed in a feedback loop to provide a satisfactorily refined sample and optimized purification/separation settings.

    摘要翻译： 本发明提供了定量，纯化和分离富勒烯如单壁碳纳米管（SWNT）的系统和方法。 纯化/分离组合从给定的不纯样品提供近100％含碳杂质的SWNT含量，并从给定的非分离样品提供所需的手性和直径。 纯化和分离成功的纳米学验证在单一系统中使用热释电检测器和拉曼光谱，从而为纳米制造环境提供了关键方面。 纯化/分离和纳米体系验证可以在反馈回路中进行，以提供令人满意的精制样品和优化的纯化/分离设置。

    Automatic Control Systems for Aircraft Auxiliary Power Units, and Associated Methods
    4.
    发明申请
    Automatic Control Systems for Aircraft Auxiliary Power Units, and Associated Methods 有权
    飞机辅助动力装置自动控制系统及相关方法

    公开(公告)号：US20090037036A1

    公开(公告)日：2009-02-05

    申请号：US12047833

    申请日：2008-03-13

    申请人： Phuong H. Nguyen ,  Joseph A. Sikora ,  Thomas A. Campbell

    发明人： Phuong H. Nguyen ,  Joseph A. Sikora ,  Thomas A. Campbell

    IPC分类号： F02C7/00

    CPC分类号： B64D41/00 ,  B64D2041/002 ,  B64D2221/00

    摘要： Systems and methods for operating aircraft power systems are disclosed. A power system in accordance with one embodiment of the invention includes an aircraft auxiliary power unit and a controller coupled to the aircraft auxiliary power unit, with the controller being configured to automatically stop the auxiliary power unit while the auxiliary power unit is functioning normally. The controller can also be configured to automatically start the auxiliary power unit in-flight when power supplied or expected to be supplied to a subsystem of the aircraft has a non-zero value at or below a threshold value. The controller may also be configured to start the auxiliary power unit when a load or expected load on the subsystem meets or exceeds a threshold value.

    摘要翻译： 公开了用于操作飞机动力系统的系统和方法。 根据本发明的一个实施例的电力系统包括飞行器辅助动力单元和耦合到飞行器辅助动力单元的控制器，其中控制器被配置为在辅助动力单元正常运行时自动停止辅助动力单元。 控制器还可以被配置为在供电或期望提供给飞行器的子系统的电源具有等于或小于阈值的非零值时，在飞行中自动启动辅助电源单元。 控制器还可以被配置为在子系统上的负载或预期负载满足或超过阈值时启动辅助电源单元。

    Adaptive DPCA subsystem
    6.
    发明授权
    Adaptive DPCA subsystem 失效
    自适应DPCA子系统

    公开(公告)号：US5703593A

    公开(公告)日：1997-12-30

    申请号：US571001

    申请日：1995-12-12

    申请人： Thomas A. Campbell ,  Heinz H. Schreiber ,  Niki Yioves

    发明人： Thomas A. Campbell ,  Heinz H. Schreiber ,  Niki Yioves

    IPC分类号： G01S13/44 ,  G01S13/524 ,  G01S13/72 ,  G01S13/534

    CPC分类号： G01S13/4472 ,  G01S13/5242 ,  G01S13/449 ,  G01S13/5244 ,  G01S13/726

    摘要： An ADPCA subsystem includes a weight processor for weighting the delta channel signal according to the results of an adaptive algorithm to which the output of a DPCA vector combiner is input. An AMTI vector combiner is connected to the output of the DPCA vector combiner to form the filter output. The delta channel signal is time delayed and samples of the delta channel signal are collected by the processor together with a sum channel sample and a residue sample, in order to apply the proper weights to the undelayed and delayed delta channel samples. The output of the ADPCA weight processor therefore provides an optimum correction signal to the vector combiner.

    摘要翻译： ADPCA子系统包括权重处理器，用于根据输入DPCA矢量组合器的输出的自适应算法的结果对增量信道信号进行加权。 AMTI矢量组合器连接到DPCA矢量组合器的输出端以形成滤波器输出。 Δ信道信号是时间延迟的，并且Δ信道信号的样本由处理器与和信道样本和残差采样一起收集，以便将适当的权重应用于未延迟和延迟的三角形信道样本。 因此，ADPCA加权处理器的输出为矢量组合器提供最佳校正信号。

    Dual flow APU inlet and associated systems and methods
    7.
    发明授权
    Dual flow APU inlet and associated systems and methods 有权
    双流APU入口及相关系统和方法

    公开(公告)号：US07611093B2

    公开(公告)日：2009-11-03

    申请号：US11829497

    申请日：2007-07-27

    申请人： Thomas A. Campbell ,  David S. Chambers ,  Robert H. Willie ,  Charles W. Rust

    发明人： Thomas A. Campbell ,  David S. Chambers ,  Robert H. Willie ,  Charles W. Rust

    IPC分类号： B64D41/00

    CPC分类号： F02C7/04 ,  B64D41/00 ,  B64D2033/0213 ,  B64D2041/002 ,  F02C6/06 ,  F02C7/042 ,  Y02T50/44 ,  Y02T50/671 ,  Y10T137/0536

    摘要： Dual flow auxiliary power unit (APU) inlets and associated systems and methods are disclosed. An inlet in accordance with one embodiment of the invention includes an entrance aperture and a divider positioned in the inlet and located to separate a first portion of the inlet from a second portion of the inlet. The first portion can be configured to couple to an engine air intake of an APU, and the second portion can be configured to direct air away from the air intake. The divider can be positioned to direct air having a first total pressure level and a first distortion level to the first portion of the inlet, and direct air having a second total pressure level and second distortion level to the second portion of the inlet. The first total pressure level can be approximately the same as or higher than the second total pressure level, or the second distortion level can be approximately the same as or higher than the first distortion level, or both.

    摘要翻译： 公开了双流辅助动力单元（APU）入口及相关系统和方法。 根据本发明的一个实施例的入口包括入口孔和分隔件，其定位在入口中并且定位成将入口的第一部分与入口的第二部分分开。 第一部分可以被配置成联接到APU的发动机进气口，并且第二部分可被配置成将空气引导离开进气口。 分隔器可以定位成将具有第一总压力水平和第一失真水平的空气引导到入口的第一部分，并且具有第二总压力水平和第二失真水平的直接空气到入口的第二部分。 第一总压力水平可以大致等于或高于第二总压力水平，或者第二失真水平可以大致等于或高于第一失真水平，或两者。

    Automatic control systems for aircraft auxiliary power units, and associated methods
    8.
    发明授权
    Automatic control systems for aircraft auxiliary power units, and associated methods 有权
    飞机辅助动力装置自动控制系统及相关方法

    公开(公告)号：US08061650B2

    公开(公告)日：2011-11-22

    申请号：US13021422

    申请日：2011-02-04

    申请人： Phuong H. Nguyen ,  Joseph A. Sikora ,  Thomas A. Campbell

    发明人： Phuong H. Nguyen ,  Joseph A. Sikora ,  Thomas A. Campbell

    IPC分类号： B64D41/00 ,  B60L1/00

    CPC分类号： B64D41/00 ,  B64D2041/002 ,  B64D2221/00

    摘要： Systems and methods for operating aircraft power systems are disclosed. A power system in accordance with one embodiment of the invention includes an aircraft auxiliary power unit and a controller coupled to the aircraft auxiliary power unit, with the controller being configured to automatically stop the auxiliary power unit while the auxiliary power unit is functioning normally. The controller can also be configured to automatically start the auxiliary power unit in-flight when power supplied or expected to be supplied to a subsystem of the aircraft has a non-zero value at or below a threshold value. The controller may also be configured to start the auxiliary power unit when a load or expected load on the subsystem meets or exceeds a threshold value.

    摘要翻译： 公开了用于操作飞机动力系统的系统和方法。 根据本发明的一个实施例的电力系统包括飞行器辅助动力单元和耦合到飞行器辅助动力单元的控制器，其中控制器被配置为在辅助动力单元正常运行时自动停止辅助动力单元。 控制器还可以被配置为在供电或期望提供给飞行器的子系统的电源具有等于或小于阈值的非零值时，在飞行中自动启动辅助电源单元。 控制器还可以被配置为在子系统上的负载或预期负载满足或超过阈值时启动辅助电源单元。

    Dual Flow APU Inlet and Associated Systems and Methods
    9.
    发明申请
    Dual Flow APU Inlet and Associated Systems and Methods 有权
    双流APU入口及相关系统和方法

    公开(公告)号：US20080179466A1

    公开(公告)日：2008-07-31

    申请号：US11829497

    申请日：2007-07-27

    申请人： Thomas A. Campbell ,  David S. Chambers ,  Robert H. Willie ,  Charles W. Rust

    发明人： Thomas A. Campbell ,  David S. Chambers ,  Robert H. Willie ,  Charles W. Rust

    IPC分类号： B64D33/02 ,  F02C7/04

    CPC分类号： F02C7/04 ,  B64D41/00 ,  B64D2033/0213 ,  B64D2041/002 ,  F02C6/06 ,  F02C7/042 ,  Y02T50/44 ,  Y02T50/671 ,  Y10T137/0536

    摘要： Dual flow auxiliary power unit (APU) inlets and associated systems and methods are disclosed. An inlet in accordance with one embodiment of the invention includes an entrance aperture and a divider positioned in the inlet and located to separate a first portion of the inlet from a second portion of the inlet. The first portion can be configured to couple to an engine air intake of an APU, and the second portion can be configured to direct air away from the air intake. The divider can be positioned to direct air having a first total pressure level and a first distortion level to the first portion of the inlet, and direct air having a second total pressure level and second distortion level to the second portion of the inlet. The first total pressure level can be approximately the same as or higher than the second total pressure level, or the second distortion level can be approximately the same as or higher than the first distortion level, or both.

    摘要翻译： 公开了双流辅助动力单元（APU）入口及相关系统和方法。 根据本发明的一个实施例的入口包括入口孔和分隔件，其定位在入口中并且定位成将入口的第一部分与入口的第二部分分开。 第一部分可以被配置成联接到APU的发动机进气口，并且第二部分可被配置成将空气引导离开进气口。 分隔器可以定位成将具有第一总压力水平和第一失真水平的空气引导到入口的第一部分，并且具有第二总压力水平和第二失真水平的直接空气到入口的第二部分。 第一总压力水平可以大致等于或高于第二总压力水平，或者第二失真水平可以大致等于或高于第一失真水平，或两者。