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    Live display appartus for setting extenson and flexion limits in continuous passive motion (CPM) system
    2.
    发明授权
    Live display appartus for setting extenson and flexion limits in continuous passive motion (CPM) system 失效
    在连续被动运动（CPM）系统中设置伸展和屈曲极限的实时显示器

    公开(公告)号：US4807601A

    公开(公告)日：1989-02-28

    申请号：US811636

    申请日：1985-12-20

    申请人： Thomas C. Wright

    发明人： Thomas C. Wright

    IPC分类号： A61H1/02

    CPC分类号： A61H1/0255

    摘要： A live display apparatus for setting extension and flexion limits in a continuous passive motion (CPM) system. The CPM system includes a carriage for supporting a patient's limb through a range of reciprocal angular movement, a drive motor for driving the carriage, a carriage state sensor for providing a signal representative of carriage state and a control unit responsive to the carriage state sensor for controlling the drive motor. The live display apparatus includes an operator controlled extension limit select switch which is operatively coupled to the control unit. The select switch causes the carriage to be driven through its range of movement to a desired extension limit when actuated during an extension limit select mode. Data representative of the selected extension limit is stored in extension memory. An extension limit display is responsive to the control unit and provides a visual display indicative of the extension limit selected. An operator controlled flexion limit select switch is operatively coupled to the control unit, and causes the carriage to be driven through its range of movement to a desired flexion limit when actuated during a flexion limit select mode. Data representative of the selected flexion limit is stored in flexion memory. A flexion limit display provides a visual display indicative of the selected flexion limit.

    摘要翻译： 一种用于在连续被动运动（CPM）系统中设置伸展和屈曲极限的实时显示装置。 CPM系统包括用于通过一定范围的往复角运动来支撑患者肢体的托架，用于驱动托架的驱动马达，用于提供代表托架状态的信号的托架状态传感器和响应于托架状态传感器的控制单元 控制驱动电机。 实时显示装置包括可操作地耦合到控制单元的操作员控制的扩展限位选择开关。 当在延伸极限选择模式下被致动时，选择开关使滑架在其移动范围内被驱动到期望的延伸极限。 代表所选扩展限制的数据存储在扩展存储器中。 扩展限制显示响应于控制单元并且提供指示所选择的扩展限制的视觉显示。 操作者控制的弯曲限制选择开关可操作地联接到控制单元，并且当在屈曲极限选择模式下被致动时，使滑架在其运动范围内被驱动到期望的屈曲极限。 表示所选屈曲极限的数据存储在屈曲记忆体中。 弯曲限制显示提供指示所选择的屈曲极限的视觉显示。

    Atrial rate sensitive cardiac pacer circuit
    4.
    发明授权
    Atrial rate sensitive cardiac pacer circuit 失效
    心房率敏感心脏起搏电路

    公开(公告)号：US4298007A

    公开(公告)日：1981-11-03

    申请号：US170948

    申请日：1980-07-21

    申请人： Thomas C. Wright ,  Terrence R. Hudrlik ,  Perry A. Mills ,  Robert C. Rust ,  Thomas G. Wallner

    发明人： Thomas C. Wright ,  Terrence R. Hudrlik ,  Perry A. Mills ,  Robert C. Rust ,  Thomas G. Wallner

    IPC分类号： A61N1/368 ,  A61N1/36

    CPC分类号： A61N1/368

    摘要： An electrical pacer device which responds to cardiac demand so as to alter the cardiac output in a fashion to satisfy that demand. Changes in the fundamental period of the atrial electrical cycle are detected and averaged over a predetermined time interval and the resulting control signal is used to raise and lower the ventricular heart rate to increase and decrease the aforesaid cardiac output. At the same time, means are provided for continuously driving the ventricular rate toward a predetermined lower rate (the at rest rate) on a time cycle which is significantly longer than the above-mentioned predetermined time interval.

    摘要翻译： 一种响应于心脏需求以便以满足该需求的方式改变心输出量的电子起搏装置。 在预定时间间隔内检测和平均心房电循环的基本周期的变化，并且使用所得到的控制信号来提高和降低心室心率以增加和减少上述心输出量。 同时，提供了用于在明显长于上述预定时间间隔的时间周期上将心室率持续地驱动到预定的较低速率（静止时）的装置。

    Safety features for continuous motion therapy system
    6.
    发明授权
    Safety features for continuous motion therapy system 失效
    连续运动治疗系统的安全特征

    公开(公告)号：US4798197A

    公开(公告)日：1989-01-17

    申请号：US24232

    申请日：1987-03-10

    申请人： Robert H. Nippoldt ,  Gary A. Rocheleau ,  Thomas C. Wright

    发明人： Robert H. Nippoldt ,  Gary A. Rocheleau ,  Thomas C. Wright

    IPC分类号： A61H1/02

    CPC分类号： A61H1/02 ,  A61H1/0255 ,  A61H2201/10 ,  A61H2201/1215 ,  A61H2201/1623 ,  A61H2201/1633 ,  A61H2201/164 ,  A61H2201/1664 ,  A61H2201/1676 ,  A61H2201/5058 ,  A61H2201/5064 ,  A61H2201/5066 ,  A61N1/00

    摘要： Safety features for a continuous motion therapy system of the type including a carriage for supporting a patient's limb, a drive unit for driving the carriage through a range of reciprocal angular movement, first and second channel neuromuscular stimulators for applying electrical stimulation to muscles of a patient's limb, and a controller for controlling the drive unit and stimulators. Both stimulator channels must be turned OFF after the controller is powered up before either stimulator channel will operate. The drive unit is enclosed by a cover. When pressure on the cover is sensed, the controller stops and reverses the direction of the carriage. The drive unit includes a drive motor which is coupled to the carriage by a linkage. Limit switches provide limit signals when the linkage reaches predetermined limit positions. In response, the controller stops and reverses direction of the carriage. A remote patient controller which is coupled to the controller by a multiconductor cable permits the patient to control motion of the carriage from a remote location. Should the cable be disconnected from the controller, or should any lead therein become open or short circuited, the controller causes motion of the carriage to stop either immediately or after the remote patient controller is again actuated.

    摘要翻译： 一种用于连续运动治疗系统的安全特征，包括用于支撑病人肢体的托架，用于通过一定范围的往复角运动来驱动托架的驱动单元，用于向病人的肌肉施加电刺激的第一和第二通道神经肌肉刺激器 肢体和用于控制驱动单元和刺激器的控制器。 控制器上电之后，两个刺激器通道都必须关闭，然后才能在任何一个刺激通道运行。 驱动单元由盖子包围。 当感应到盖子上的压力时，控制器停止并反转滑架的方向。 驱动单元包括驱动马达，其通过连杆联接到滑架。 当连杆到达预定极限位置时，限位开关提供极限信号。 作为响应，控制器停止并反转托架的方向。 通过多导体电缆耦合到控制器的远程患者控制器允许患者控制托架从远程位置的运动。 如果电缆与控制器断开连接，或者其中任何导线处于打开或短路状态，则控制器会立即或在远程患者控制器再次启动后立即停止。

    NMS aided continuous passive motion apparatus
    8.
    发明授权
    NMS aided continuous passive motion apparatus 失效
    NMS辅助连续被动运动装置

    公开(公告)号：US4520827A

    公开(公告)日：1985-06-04

    申请号：US578470

    申请日：1984-02-09

    申请人： Thomas C. Wright ,  Stephen H. Ober

    发明人： Thomas C. Wright ,  Stephen H. Ober

    IPC分类号： A61H1/02 ,  A61N1/36

    CPC分类号： A61H1/0255 ,  A61N1/36003 ,  A61H2201/10

    摘要： A continuous passive motion (CPM) apparatus mobilizes the knee joint of a patient's leg. In order to achieve total extension of the leg, the CPM apparatus pauses each time the extension end position is reached. A neuro-muscular stimulator (NMS) is enabled to provide stimulation to the patient's quadriceps muscle to effect a total extension of the leg. At the end of the pause interval, the NMS turns off, and the CPM resumes motion.

    摘要翻译： 连续被动运动（CPM）装置动员患者腿部的膝关节。 为了实现腿的总伸展，CPM设备在每次到达延伸结束位置时暂停。 神经肌肉刺激器（NMS）能够为患者的股四头肌提供刺激以实现腿部的全部伸展。 在暂停间隔结束时，NMS关闭，CPM恢复运动。

    Detection of high oncogenic-risk papilloma virus in high grade cervical lesions and cancers by a PCR/ELISA assay
    9.
    发明授权
    Detection of high oncogenic-risk papilloma virus in high grade cervical lesions and cancers by a PCR/ELISA assay 失效
    通过PCR / ELISA测定检测高级宫颈病变和癌症中的高致癌风险乳头瘤病毒

    公开(公告)号：US5888724A

    公开(公告)日：1999-03-30

    申请号：US479777

    申请日：1995-06-07

    申请人： Saul J. Silverstein ,  Octavian Lungu ,  Thomas C. Wright ,  Ralph M. Richart

    发明人： Saul J. Silverstein ,  Octavian Lungu ,  Thomas C. Wright ,  Ralph M. Richart

    IPC分类号： C12Q1/68 ,  C12Q1/70 ,  G01N33/574 ,  C12P19/34

    CPC分类号： C12Q1/686 ,  C12Q1/6804 ,  C12Q1/708 ,  G01N33/57411

    摘要： This invention provides a method of detecting a high oncogenic-risk type human papillomavirus in a subject which comprises: obtaining from a subject a specimen containing cervical cells and treating the specimen so as to recover nucleic acid molecules present in the cervical cells; contacting the resulting nucleic acid molecules with multiple pairs of single-stranded labeled oligonucleotide primers capable of specifically hybridizing with a different high oncogenic-risk type of human papillomavirus; amplifying any nucleic acid molecules to which a pair of primers hybridizes so as to obtain a double-stranded amplification product and treating any double-stranded amplification product so as to obtain single-stranded nucleic acid molecules; contacting any resulting single-stranded nucleic acid molecules with multiple single-stranded labeled oligonucleotide probes which are capable of specifically hybridizing with such high oncogenic-risk types of human papillomavirus; contacting any resulting hybrids with a marked antibody capable of specifically forming a complex with the labeled probe, when the probe is present in such a complex; and detecting the presence of any resulting complexes, the presence thereof being indicative of the presence of a high oncogenic-risk type human papillomavirus in the initial specimen.

    摘要翻译： 本发明提供一种检测受试者中高致癌危险型人乳头瘤病毒的方法，包括：从受试者获得含有宫颈细胞的标本并处理该标本以回收存在于宫颈细胞中的核酸分子; 使得到的核酸分子与能够与不同的高致癌危险类型的人乳头瘤病毒特异性杂交的多对单链标记寡核苷酸引物接触; 扩增一对引物杂交的任何核酸分子，以获得双链扩增产物并处理任何双链扩增产物，从而获得单链核酸分子; 使任何得到的单链核酸分子与能够与这种高致癌风险类型的人乳头瘤病毒特异性杂交的多个单链标记的寡核苷酸探针接触; 当所述探针存在于所述复合物中时，使所得到的杂交体与能够与标记的探针特异形成复合物的标记抗体接触; 并检测任何所得复合物的存在，其存在表明初始样品中存在高致癌危险型人乳头瘤病毒。