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公开(公告)号:US12052551B2
公开(公告)日:2024-07-30
申请号:US18171175
申请日:2023-02-17
发明人: Jonathan S. Abel , Eoin F. Callery
IPC分类号: H04R3/02
CPC分类号: H04R3/02
摘要: The present embodiments generally relate to enabling participants in an online gathering with networked audio to use a cancelling auralizer at their respective locations to create a common acoustic space or set of acoustic spaces shared among subgroups of participants. For example, there are a set of network connected nodes, and the nodes can contain speakers and microphones, as well as participants and node mixing-processing blocks. The node mixing-processing blocks generate and manipulate signals for playback over the node loudspeakers and for distribution to and from the network. This processing can include cancellation of loudspeaker signals from the microphone signals and auralization of signals according to control parameters that are developed locally and from the network. A network block can contain network routing and processing functions, including auralization, synthesis, and cancellation of audio signals, synthesis and processing of control parameters, and audio signal and control parameter routing.
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公开(公告)号:US20240229159A1
公开(公告)日:2024-07-11
申请号:US18573842
申请日:2022-06-30
发明人: Colum Dunne , Patrick Kiely , Joanne Nolan , Ailish Hannigan , Shona Tormey , Anne Merrigan , Mary McCumiskey
IPC分类号: C12Q1/6886 , G16B25/10
CPC分类号: C12Q1/6886 , G16B25/10 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158
摘要: A method for determining the presence or absence of lymph node metastasis in a breast cancer subject is provided. The method comprises the steps of assaying for expression of genes (or proteins encoded by the genes) ITGB4 and SNAI2 in a sample from the subject, wherein an increased expression of ITGB4 and a decreased expression of SNAI2 compared with the expression of the same genes (or proteins encoded by said genes) in a subject without cancer is indicative of the absence of lymph node metastasis in said subject. or wherein an increased expression of SNAI2 and a decreased expression of ITGB4 compared with the expression of the same genes (or proteins encoded by said genes) in a subject without cancer is indicative of the presence of lymph node metastasis in said subject.
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公开(公告)号:US20240011855A1
公开(公告)日:2024-01-11
申请号:US18247159
申请日:2021-09-28
IPC分类号: G01L9/00
CPC分类号: G01L9/0042 , G01L9/0079
摘要: The present invention relates to a diaphragm for a pressure sensor, the diaphragm comprising a hybrid sol-gel film. The invention also extends to a process for the manufacture of said diaphragm for a pressure sensor and to a pressure sensor comprising said diaphragm.
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公开(公告)号:US20230285932A1
公开(公告)日:2023-09-14
申请号:US17913038
申请日:2021-03-19
CPC分类号: B01J20/226 , B01D53/02 , B01D53/261 , B01J20/3085 , B01J20/3425 , B01J20/3483 , B01J20/3491 , C02F1/288 , B01D2257/80 , C02F2103/08
摘要: A method of capturing water from a composition comprising water or water vapour using a hybrid ultramicroporous material. The method comprises the steps of: (a) providing a hybrid ultramicroporous material of formula [M(L)a(X)b]; and (b) contacting the hybrid ultramicroporous material with the composition comprising water to capture water into the hybrid ultramicroporous material; The hybrid ultramicroporous materials used in the method of the present invention have fast kinetics of water uptake and high working capacity compared to known commercial sorbent materials. The method of the present invention may be used in water capture and purification processes to provide fresh water suitable for drinking or for use in agriculture. The method of the present invention may also be used to remove water as a contaminant or for use in dehumidification processes. A use of such a hybrid ultramicroporous material and a device for capturing water are also disclosed.
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公开(公告)号:US20230111202A1
公开(公告)日:2023-04-13
申请号:US17904511
申请日:2021-02-19
发明人: Luis PADRELA , Vivek VERMA , Kevin RYAN
IPC分类号: A61K9/16 , B05D1/12 , A61K31/55 , A61K31/519 , A61K31/192 , A61K31/549
摘要: A method of producing a particle coating on one or more items is provided. The method comprises mixing supercritical carbon dioxide with a solution comprising dissolved material for forming particles. The method further comprises spraying the mixture into a precipitation chamber (316) to precipitate particles, wherein the chamber is at a pressure below a supercritical pressure of the supercritical fluid. The method also comprises capturing the precipitated particles on one or more items located within the chamber.
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公开(公告)号:US11323019B2
公开(公告)日:2022-05-03
申请号:US16954185
申请日:2018-12-17
发明人: Eamon O'Malley , Patrick Meehan , Karl Rinne
摘要: A switched mode power supply converter comprises a circuit pulse matching circuit configured to negate output voltage disturbance or noise during switching operation of a power conversion. The current pulse matching circuit input is driven by, or from, a power converter switch node of the switched mode power supply converter. The current pulse matching circuit comprises a rate-of-voltage change detection circuit driven by the power converter switch node.
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公开(公告)号:US11266521B2
公开(公告)日:2022-03-08
申请号:US16088810
申请日:2017-03-16
发明人: Rhona Hunt , Kevin Kelleher , Leonard O'Sullivan
摘要: An ostomy attachment comprises a flexible annular seal configured to embrace a stoma and a spout that in use is disposed beneath the stoma and configured to collect ostomy output at skin level and direct ostomy output away from the patient and annular seal and into an ostomy bag, in which the flexible annular seal is formed from an absorbent material and the spout is formed from a non-absorbent material. The annular seal may be an open ring comprising at least one mouldable arm that in use can be wrapped at least partially around the patients' stoma.
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公开(公告)号:US20220054731A1
公开(公告)日:2022-02-24
申请号:US17222278
申请日:2021-04-05
发明人: Jakki Cooney , Todd Fumio Kagawa , Edmond Magner
摘要: An apparatus for the extracorporeal treatment of blood comprising an extracorporeal blood circuit (2), a pump (6) configured to provide fluid displacement within the extracorporeal blood circuit, and a reaction chamber (8) connected to the extracorporeal blood circuit and configured to receive blood or plasma from the circuit and treat the blood or plasma. The reaction chamber comprises a protease enzyme immobilized to a support, in which the protease enzyme is specific for, and capable of irreversibly cleaving, a human C5a present in the blood or plasma, wherein the abundance of the human C5a in the treated blood or plasma is less than that in the untreated blood or plasma. The apparatus finds utility in the extracorporeal treatment of blood from patients with inflammatory conditions, especially auto-immune disease and sepsis.
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公开(公告)号:US20210243899A1
公开(公告)日:2021-08-05
申请号:US17051723
申请日:2019-05-02
发明人: John Harris , Jennifer Hennessy , Seamus Clifford , Mark Southern
摘要: A PCB, printed circuit board, structure for forming at least one embedded electronic component. The structure comprises a multi-layer PCB board comprising at least one through-hole via, the via comprising a plurality of electrodes vertically aligned within the via, each electrode comprising a plated ring; and an isolation section separating each of the electrodes.
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公开(公告)号:US20210114088A1
公开(公告)日:2021-04-22
申请号:US17054117
申请日:2019-05-14
发明人: Jennifer Hennessy , John Harris , Mark Southern
摘要: A method and apparatus for real-time in-mould marking of a moulded or cast form with an identifier in which a configurable marking module (1) with phase change actuators (23) in the form of a multi-layered printed circuit board assembly (1) with a vertical element (33) having a marker (21) is installed in a mould (2), (35), the marker (21) being remotely configurable by a controller to create a unique identifier which is applied to the form in the mould.
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