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公开(公告)号：US07125549B2
公开(公告)日：2006-10-24
申请号：US10297099
申请日：2001-05-31
IPC分类号： C12N15/63 , C12N15/64 , C12N15/861 , C12N15/867 , C12N15/869
CPC分类号： C12N15/86 , A61K38/00 , A61K48/00 , C12N7/00 , C12N2710/10343
摘要： The invention includes a viral vector method and composition comprising transcomplementary replication incompetent viral vectors, preferably adenoviral vectors, which are cotransformed to a recipient cell. The two vectors complement each other and thus allow viral replication, in a synergistic combination which enhances both gene delivery and gene expression of genetic sequences contained within the vector.
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2.发明授权Methods and compositions for efficient gene transfer using transcomplementary vectors 有权使用反辅助载体进行有效基因转移的方法和组合物公开(公告)号：US06875610B2
公开(公告)日：2005-04-05
申请号：US09871183
申请日：2001-05-31
CPC分类号： C12N15/86 , A61K38/00 , A61K48/00 , C12N7/00 , C12N2710/10343
摘要： The invention includes a viral vector method and composition comprising transcomplementary replication incompetent viral vectors, preferably adenoviral vectors, which are cotransformed to a recipient cell. The two vectors complement each other and thus allow viral replication, in a synergistic combination which enhances both gene delivery and gene expression of genetic sequences contained within the vector.
摘要翻译： 本发明包括病毒载体方法和组合物，其包含转运到受体细胞的反式互补复制无能病毒载体，优选腺病毒载体。 两个载体彼此互补，从而允许病毒复制，其协同组合增强载体中包含的遗传序列的基因递送和基因表达。
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公开(公告)号：US06238858B1
公开(公告)日：2001-05-29
申请号：US09058686
申请日：1998-04-10
IPC分类号： C12Q170
CPC分类号： C12N15/86 , A61K48/00 , C12N7/00 , C12N2710/10321 , C12N2710/10344 , C12N2740/13043 , C12N2740/13051 , C12N2740/13052 , C12N2770/36143 , C12N2840/203
摘要： The present invention provides chimeric primary viruses, which are capable of producing secondary viruses in a producer host cell, and methods of making the same.
摘要翻译： 本发明提供能够在生产者宿主细胞中产生次级病毒的嵌合型初级病毒及其制备方法。
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公开(公告)号：US4420154A
公开(公告)日：1983-12-13
申请号：US205929
申请日：1980-11-12
申请人： John T. Ramsey , William J. Ramsey
发明人： John T. Ramsey , William J. Ramsey
IPC分类号： A63B21/078 , A63B21/06
CPC分类号： A63B21/078
摘要： A weightlifting apparatus and method for preventing injury to a weightlifter from a weightlifting bar including weights thereon in the event of physical collapse of the weightlifter. The apparatus includes a framework having a base, a brace, a first pair of vertical support members secured to the brace and to the base and having a first slot therebetween with a structure defining a plurality of first apertures; and a second pair of vertical support members secured to the brace and to the base and having a second slot therebetween with a structure defining a plurality of second apertures. An adjustment body with adjustment apertures is slidably and adjustably mounted within the first slot and another adjustment body within the second slot. A bolt is threadably secured to the adjustment body for finely adjusting the height of a resting weightlifting bar with respect to a weightlifter. The process comprises placing the adjustment body within the first slot and the second slot, and inserting a pin through the first apertures and the adjustment apertures to retain one of the adjustment bodies within the first slot, and inserting another pin through the second apertures and the adjustment apertures of another adjustment body to retain the other adjustment body in the second slot.
摘要翻译： 一种举重装置和方法，用于在起重机物理塌陷的情况下，防止来自举重杆的举重运动员的损伤，包括其上的重物。 该装置包括具有底座，支架，固定到支架和底座的第一对垂直支撑构件的框架，并且其间具有限定多个第一孔的结构的第一槽; 以及第二对垂直支撑构件，其固定到所述支撑件和所述基部并且在其间具有限定多个第二孔的结构的第二槽。 具有调节孔的调节体可滑动并可调节地安装在第一狭槽内，而另一个调节体在第二狭槽内。 螺栓螺纹地固定到调节体上，用于相对于举重运动器微调静态举重杆的高度。 该过程包括将调节体放置在第一槽和第二槽内，以及通过第一孔和调节孔插入销以将调节体中的一个保持在第一槽内，以及将另一个销插入第二孔和 另一调节体的调节孔将另一个调节体保持在第二槽中。
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