公开(公告)号：US20170224990A1

公开(公告)日：2017-08-10

申请号：US15264224

申请日：2016-09-13

申请人： Isy GOLDWASSER ,  William J. TYLER ,  Jonathan CHARLESWORTH ,  Sumon K. PAL ,  Daniel Z. WETMORE ,  Douglas JEFFERY ,  Wing LAW ,  Jason EGNAL ,  Anil THAKUR ,  Remi DEMERS ,  Jay Frederick HAMLIN ,  Rafal PIERSIAK

发明人： Isy GOLDWASSER ,  William J. TYLER ,  Jonathan CHARLESWORTH ,  Sumon K. PAL ,  Daniel Z. WETMORE ,  Douglas JEFFERY ,  Wing LAW ,  Jason EGNAL ,  Anil THAKUR ,  Remi DEMERS ,  Jay Frederick HAMLIN ,  Rafal PIERSIAK

IPC分类号： A61N1/36 ,  A61N1/04

摘要： Apparatuses (e.g., devices, systems), and methods for transdermal electrical stimulation (TES). Apparatuses described herein can be self-contained, lightweight, and wearable. The apparatuses and methods described herein be configured to apply an ensemble current waveform between the two or more electrodes, wherein the ensemble current waveform comprises a series of component waveforms that are sequentially applied, and wherein each component waveform is different from a component waveform immediately before it and wherein transitions between the component waveforms temporally correlates with transitions in the sensory experience. Also described are neurostimulators for application of transdermal electrical stimulation (TES) and methods of using them for comfortably inducing a cognitive effect. Also described are Methods and apparatuses for amplitude modulation of all or a portion of an ensemble waveform to modify a user's cognitive state by transdermal electrical stimulation (TES).

公开(公告)号：US08443226B2

公开(公告)日：2013-05-14

申请号：US13099824

申请日：2011-05-03

申请人： Svetlana Samoilova ,  Wing Law ,  Andrew Bart Hodge

发明人： Svetlana Samoilova ,  Wing Law ,  Andrew Bart Hodge

IPC分类号： G06F11/00

CPC分类号： G06F11/2294

摘要： Systems and methods for reducing the cost and time required for diagnosing and fixing electronic devices are provided. A host electronic device may be configured to generate a log of events that it experiences. A help component may access the generated log and analyze the log to detect if the host device has experienced a problem. Data may then be exchanged between the help component and the host device in order to fix the detected problem.

摘要翻译： 提供了用于降低诊断和固定电子设备所需的成本和时间的系统和方法。 主机电子设备可以被配置为生成其经历的事件的日志。 帮助组件可以访问生成的日志并分析日志以检测主机设备是否遇到问题。 然后可以在帮助组件和主机设备之间交换数据，以便修复检测到的问题。

公开(公告)号：US20070008546A1

公开(公告)日：2007-01-11

申请号：US11178077

申请日：2005-07-08

申请人： Ho Ho ,  Chi Wong ,  Shu Wu ,  Wing Law ,  Chinlon Lin ,  Sui Kong

发明人： Ho Ho ,  Chi Wong ,  Shu Wu ,  Wing Law ,  Chinlon Lin ,  Sui Kong

IPC分类号： G01B9/02 ,  G01N21/41

CPC分类号： G01N21/553 ,  G01N21/45

摘要： Disclosed is an optical sensing device, which comprises a light source emitting a light; a beam splitter; an SPR sensor unit comprising a sensing surface; and a detecting mechanism; and a converting unit converting the first beam and the second beam from the optical device into a two-dimensional interference fringe pattern. From the above-mentioned configuration, an extra phase shift of a detection beam in SPR phase measurement is obtained. The differential measurement approach has shown to achieve a sensitivity figure significantly better than the best result that can be obtained from the prior art in the field of the measurement based on an SPR sensor.

摘要翻译： 公开了一种光学感测装置，其包括发光的光源; 分束器; SPR传感器单元，包括感测表面; 和检测机构; 以及转换单元，将第一光束和第二光束从光学装置转换为二维干涉条纹图案。 根据上述结构，可以得到SPR相位测定中的检测光束的额外的相移。 微分测量方法已经表明，实现了比基于SPR传感器的测量领域中现有技术可以获得的最佳结果明显更好的灵敏度图。

公开(公告)号：US4742829A

公开(公告)日：1988-05-10

申请号：US895343

申请日：1986-08-11

申请人： Wing Law ,  Wayne Barbour ,  Axel F. Brisken

发明人： Wing Law ,  Wayne Barbour ,  Axel F. Brisken

IPC分类号： A61B8/08 ,  A61B8/12 ,  A61B10/00 ,  A61B10/02 ,  A61B17/34

CPC分类号： A61B10/0291 ,  A61B17/3403 ,  A61B8/0841 ,  A61B8/0866 ,  A61B8/12 ,  A61B2017/3413 ,  A61B8/445

摘要： An ultrasound probe for positioning in the vaginal cavity includes a phased array of transducer elements at one end thereof oriented at an acute angle with respect to the central axis of the probe whereby the imaging field of view is provided by rotating the probe. A biopsy needle assembly snaps onto slots on the probe with a fork and socket fit. A handle on the probe is offset from the central axis of the probe thereby freeing the space around the entrance to the needle guide and facilitating the manipulation by hand of a needle in the guide.

摘要翻译： 用于定位在阴道腔中的超声探头包括在其一端相对于探针的中心轴线成锐角定向的换能器元件的相控阵列，由此通过旋转探针来提供成像视场。 活检针组件通过叉和插座配合到探针上的槽上。 探针上的把手与探针的中心轴线偏移，从而释放针引导入口周围的空间，并且便于手中引导器中的针的操作。

公开(公告)号：US20160346530A1

公开(公告)日：2016-12-01

申请号：US15169445

申请日：2016-05-31

申请人： Douglas JEFFERY ,  Wing LAW ,  Jay Frederick HAMLIN ,  Remi DEMERS ,  Rafal PIERSIAK

发明人： Douglas JEFFERY ,  Wing LAW ,  Jay Frederick HAMLIN ,  Remi DEMERS ,  Rafal PIERSIAK

IPC分类号： A61N1/04 ,  A61N1/36

CPC分类号： A61N1/0492 ,  A61M16/0688 ,  A61M21/02 ,  A61M2021/0072 ,  A61M2205/3306 ,  A61M2205/3324 ,  A61M2205/3375 ,  A61M2210/0687 ,  A61M2230/10 ,  A61M2230/63 ,  A61N1/0456 ,  A61N1/048 ,  A61N1/0488 ,  A61N1/0526 ,  A61N1/36014 ,  A61N1/36025 ,  A61M2230/005

摘要： Methods and apparatuses for transdermal electrical stimulation. Described herein are single-use or limited-use TES apparatuses and methods of using them that include an integrated (e.g., flex-circuit) electrode assembly and controller apparatus including a waveform generator and power supply. Also described herein are TES apparatuses including a cord or wire having current control circuitry and configured to connect a mobile computing device (e.g., smartphone or wearable electronics) to an electrode assembly. Finally, also described herein are intermediate apparatuses including a flex-circuit electrode assembly including a waveform generator but receiving power from a cable connected to a mobile computing device.

摘要翻译： 透皮电刺激的方法和装置。 这里描述的是使用它们的一次性或有限使用的TES装置和方法，其包括集成（例如柔性电路）电极组件和包括波形发生器和电源的控制器装置。 本文还描述了包括具有电流控制电路并被配置为将移动计算设备（例如，智能电话或可穿戴电子设备）连接到电极组件的电缆或电线的TES设备。 最后，这里也描述了包括包括波形发生器的柔性电路电极组件的中间设备，但是从连接到移动计算设备的电缆接收电力。

公开(公告)号：US20170252562A1

公开(公告)日：2017-09-07

申请号：US15601394

申请日：2017-05-22

申请人： Isy GOLDWASSER ,  Douglas JEFFERY ,  Sumon K. PAL ,  Wing LAW

发明人： Isy GOLDWASSER ,  Douglas JEFFERY ,  Sumon K. PAL ,  Wing LAW

IPC分类号： A61N1/36 ,  A61N1/04 ,  A61M21/02

CPC分类号： A61N1/36025 ,  A61M21/02 ,  A61M2021/0072 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/048 ,  A61N1/0484 ,  A61N1/0492 ,  A61N1/3603 ,  A61N1/36034

摘要： Described herein are methods and apparatuses for the application of transdermal electrical stimulation (TES) in order to modulate a user's cognitive state to induce a state of calm or relaxation. The apparatuses described herein include neck-worn devices having electrodes (or configured to connect to electrodes, including automatically self-connecting to electrodes) adapted to couple to the midline of the back of user's neck. A neck-worn controller may be configured as a cord, band, wire, torc, necklace, loop, strap, or the like, and may be rigid or semi-rigid and may be worn at least partially around the subject's neck. The controller may controllably apply one or more waveforms to the electrodes of the electrode pad (e.g., patch) to deliver TES adapted to induce or enhance a relaxed cognitive state.

公开(公告)号：US20150335877A1

公开(公告)日：2015-11-26

申请号：US14634664

申请日：2015-02-27

申请人： Douglas JEFFERY ,  Isy GOLDWASSER ,  Wing LAW ,  Remi DEMERS ,  Jay Frederick HAMLIN ,  Daniel Z. WETMORE ,  Sumon K. PAL ,  Jonathan CHARLESWORTH ,  William J. TYLER

发明人： Douglas JEFFERY ,  Isy GOLDWASSER ,  Wing LAW ,  Remi DEMERS ,  Jay Frederick HAMLIN ,  Daniel Z. WETMORE ,  Sumon K. PAL ,  Jonathan CHARLESWORTH ,  William J. TYLER

IPC分类号： A61N1/04

CPC分类号： A61N1/0492 ,  A61N1/0456 ,  A61N1/36025

摘要： Cantilever electrode apparatuses for wearable neuromodulation devices configured to be worn on a subject's (user's) head or on the subject's head and neck. These cantilever electrodes may mate with the wearable neuromodulation devices to form a neuromodulation system.

摘要翻译： 用于穿戴式神经调节装置的悬臂电极装置，其被配置为佩戴在受试者（用户）的头部或受试者的头部和颈部上。 这些悬臂电极可与可穿戴式神经调节装置配合，形成神经调节系统。

公开(公告)号：US20150088224A1

公开(公告)日：2015-03-26

申请号：US14558604

申请日：2014-12-02

申请人： Isy GOLDWASSER ,  William J. TYLER ,  Jonathan CHARLESWORTH ,  Sumon K. PAL ,  Daniel Z. WETMORE ,  Douglas JEFFERY ,  Wing LAW

发明人： Isy GOLDWASSER ,  William J. TYLER ,  Jonathan CHARLESWORTH ,  Sumon K. PAL ,  Daniel Z. WETMORE ,  Douglas JEFFERY ,  Wing LAW

IPC分类号： A61N1/36

CPC分类号： A61N1/36025 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/36014 ,  A61N1/36082

摘要： Apparatuses (e.g., devices, systems), and methods for transdermal electrical stimulation (TES). Apparatuses described herein can be self-contained, lightweight, and wearable. The apparatus may include a primary unit (TES stimulator) and an electrode portion that includes a first transdermal electrode and a second transdermal electrode and mates with the TES stimulator. The first electrode and secondary electrode are placed at two locations on the skin of a user, for example on the head and/or neck of a user. Electrical stimulation driven between the two electrodes may induce a cognitive effect in a user of the device.

摘要翻译： 装置（例如装置，系统）和透皮电刺激方法（TES）。 本文所述的装置可以是独立的，轻便的和可穿戴的。 该装置可以包括主单元（TES刺激器）和包括第一透皮电极和第二透皮电极并与TES刺激器配合的电极部分。 第一电极和次级电极被放置在用户皮肤上的两个位置，例如在用户的头部和/或颈部。 在两个电极之间驱动的电刺激可能在装置的使用者中引起认知效果。

公开(公告)号：US20150335888A1

公开(公告)日：2015-11-26

申请号：US14715470

申请日：2015-05-18

申请人： Remi DEMERS ,  Jay Frederick HAMLIN ,  Wing LAW ,  Sumon K. PAL ,  Jonathan CHARLESWORTH

发明人： Remi DEMERS ,  Jay Frederick HAMLIN ,  Wing LAW ,  Sumon K. PAL ,  Jonathan CHARLESWORTH

IPC分类号： A61N1/36 ,  A61N1/04

CPC分类号： A61N1/0456 ,  A61N1/0492 ,  A61N1/36025

摘要： Neurostimulators for application of transdermal electrical stimulation (TES) and methods of using them for comfortably inducing a cognitive effect. The apparatuses described herein may include hardware, software and/or firmware components that are configured to safely and effectively apply high current intensity (e.g., using a high voltage source). These apparatuses may also include circuitry configured to deliver complex (e.g., ensemble) TES current waveforms that incorporate capacitive discharge current at selected portions of the delivered waveform to enhance user comfort. Methods of operating these devices to reduce capacitance buildup on the user's skin by delivering integrated capacitive discharging currents are also included.

摘要翻译： 用于应用透皮电刺激（TES）的神经刺激器和使用它们舒适地诱导认知效应的方法。 本文描述的装置可以包括被配置为安全且有效地施加高电流强度（例如，使用高电压源）的硬件，软件和/或固件组件。 这些装置还可以包括经配置以在所输送的波形的选定部分输送并入电容放电电流的复合（例如，整体）TES电流波形以提高用户舒适度的电路。 还包括通过提供集成电容放电电流来操作这些器件以减少用户皮肤上的电容积累的方法。

公开(公告)号：US20110208993A1

公开(公告)日：2011-08-25

申请号：US13099824

申请日：2011-05-03

申请人： Svetlana Samoilova ,  Wing Law ,  Andrew Bart Hodge

发明人： Svetlana Samoilova ,  Wing Law ,  Andrew Bart Hodge

IPC分类号： G06F11/07

CPC分类号： G06F11/2294

摘要： Systems and methods for reducing the cost and time required for diagnosing and fixing electronic devices are provided. A host electronic device may be configured to generate a log of events that it experiences. A help component may access the generated log and analyze the log to detect if the host device has experienced a problem. Data may then be exchanged between the help component and the host device in order to fix the detected problem.

摘要翻译： 提供了用于降低诊断和固定电子设备所需的成本和时间的系统和方法。 主机电子设备可以被配置为生成其经历的事件的日志。 帮助组件可以访问生成的日志并分析日志以检测主机设备是否遇到问题。 然后可以在帮助组件和主机设备之间交换数据，以便修复检测到的问题。