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9 条记录 (耗时 0.019 秒)

    Vaccination Regimen for B-Cell Vaccines
    1.
    发明申请
    Vaccination Regimen for B-Cell Vaccines 审中-公开
    B细胞疫苗接种方案

    公开(公告)号：US20100119540A1

    公开(公告)日：2010-05-13

    申请号：US12594650

    申请日：2008-04-18

    申请人： Martin Bachmann ,  Patrik Maurer ,  Philipp Muller ,  Thomas Pfister ,  Wolfgang Renner

    发明人： Martin Bachmann ,  Patrik Maurer ,  Philipp Muller ,  Thomas Pfister ,  Wolfgang Renner

    IPC分类号： A61K39/385

    CPC分类号： A61K39/0013 ,  A61K47/646 ,  A61K47/6901 ,  A61K2039/5258 ,  A61K2039/55505

    摘要： This invention relates to the field of vaccination and treatment or prevention diseases. In particular this invention relates to the treatment or prevention of diseases by inducing hapten-specific antibody responses in a vaccinated subject. The invention further provides a method for prevention or treatment of a disease by inducing hapten-specific antibodies in a subject comprising administering into said subject a composition comprising a virus-like particle of an RNA bacteriophage and at least one hapten linked thereto.

    摘要翻译： 本发明涉及疫苗接种和治疗或预防疾病领域。 特别地，本发明涉及通过在接种疫苗的受试者中诱导半抗原特异性抗体应答来治疗或预防疾病。 本发明还提供了通过在受试者中诱导半抗原特异性抗体来预防或治疗疾病的方法，所述方法包括向所述受试者施用包含RNA噬菌体的病毒样颗粒和至少一种与其连接的半抗原的组合物。

    Inducible alphaviral gene expression system
    4.
    发明申请
    Inducible alphaviral gene expression system 审中-公开

    公开(公告)号：US20060024788A1

    公开(公告)日：2006-02-02

    申请号：US11177504

    申请日：2005-07-11

    申请人： Wolfgang Renner ,  Lars Nieba ,  Marco Boorsma

    发明人： Wolfgang Renner ,  Lars Nieba ,  Marco Boorsma

    IPC分类号： C12N9/22 ,  C12P21/06 ,  C12N15/86 ,  C07H21/02

    CPC分类号： C07K14/005 ,  A01K2217/05 ,  A61K48/00 ,  C12N9/127 ,  C12N15/86 ,  C12N2770/36122 ,  C12N2770/36143 ,  C12N2840/105

    摘要： The present invention provides novel expression vectors which permit tight regulation of gene expression in eucaryotic cells. More specifically, the invention provides DNA vectors comprising nucleotide sequences that are transcribed to form RNA molecules which are then replicated by a temperature-sensitive replicase to form additional RNA molecules. The RNA molecules produced by replication contain a nucleotide sequence which may be translated to produce a protein of interest or which encode one or more untranslated RNA molecules. Also provided are methods for producing heterologous proteins and untranslated RNA molecules. Further provided are methods for administering heterologous proteins and untranslated RNA molecules to individuals. In addition, pharmaceutical compositions are provided comprising the DNA and RNA molecules of the invention and a pharmaceutically acceptable carrier.

    Window lifter with a guide rail affixed on a base part
    5.
    发明授权
    Window lifter with a guide rail affixed on a base part 失效
    带导轨的窗式升降机固定在基座上

    公开(公告)号：US06425204B1

    公开(公告)日：2002-07-30

    申请号：US09636446

    申请日：2000-08-11

    申请人： Wolfgang Renner

    发明人： Wolfgang Renner

    IPC分类号： E05D1510

    CPC分类号： E05F11/382 ,  E05Y2201/684 ,  E05Y2600/322 ,  E05Y2800/26 ,  E05Y2900/55

    摘要： The invention concerns a window lifter with a guide rail (10) affixed on a base part (20) on a door inner panel, of an assembly carrier. The object of the invention is to provide a window lifter which is simple to adjust and prevents stressing of the window lifter system. This object is accomplished in that a seat (30) is formed on the base part (20), which seat is associated with a correspondingly shaped mating part (300) arranged on the guide rail (10), whereby the seat (30) and the mating part (300) are designed form-fittingly such that the guide rail (10) and the base part (20) are mounted tiltable relative to each other.

    摘要翻译： 本发明涉及一种具有导轨（10）的窗升降器，导轨（10）固定在组装架的门内板上的基部（20）上。 本发明的目的是提供一种能够调节和防止窗升降器系统的应力的窗升降器。 该目的的实现是，在基座部分（20）上形成有一个座（30），该座与相应配置在导轨（10）上的配合部件（300）相连，由此座椅（30）和 配合部件（300）的形状配合成使得导轨（10）和基部部件（20）相对于彼此可倾斜安装。

    Inducible alphaviral/orip based gene expression system
    7.
    发明申请
    Inducible alphaviral/orip based gene expression system 审中-公开
    可诱导的基因甲基病毒/基因座基因表达系统

    公开(公告)号：US20060251620A1

    公开(公告)日：2006-11-09

    申请号：US10524818

    申请日：2003-08-21

    申请人： Lidia Ivanova ,  Wolfgang Renner ,  Philippe Saudan

    发明人： Lidia Ivanova ,  Wolfgang Renner ,  Philippe Saudan

    IPC分类号： A61K48/00 ,  C12N15/86 ,  C07H21/04

    CPC分类号： C12N15/86 ,  A61K48/00 ,  C12N15/85 ,  C12N2710/16243 ,  C12N2800/108 ,  C12N2840/20

    摘要： The present invention relates to compositions and methods that allow the production of polypeptides and untranslated RNA molecules in host cells. More specifically, the invention provides nucleic acid molecules, expression systems, recombinant host cells, methods and kits, which enable the production and/or isolation and/or purification of polypeptides and untranslated RNA molecules. The compositions and methods of the invention can be applied in a regulatable expression system that is transiently transfected into mammalian host cells.

    摘要翻译： 本发明涉及允许在宿主细胞中产生多肽和非翻译的RNA分子的组合物和方法。 更具体地，本发明提供能够产生和/或分离和/或纯化多肽和非翻译的RNA分子的核酸分子，表达系统，重组宿主细胞，方法和试剂盒。 本发明的组合物和方法可以应用于瞬时转染入哺乳动物宿主细胞的可调节表达系统中。

    Pump for fluid media
    8.
    发明授权
    Pump for fluid media 失效
    泵用于流体介质

    公开(公告)号：US4341503A

    公开(公告)日：1982-07-27

    申请号：US140413

    申请日：1980-04-14

    申请人： Alois Gschwender ,  Wolfgang Renner ,  Herbert Hahn

    发明人： Alois Gschwender ,  Wolfgang Renner ,  Herbert Hahn

    IPC分类号： F04D29/06 ,  F04D7/06 ,  F04D29/10

    CPC分类号： F04D29/106 ,  F04D7/06

    摘要： A pump for fluid media, with an inner pipe or tube arranged in a housing. A drive shaft is journalled in the inner tube, and a rotor is arranged in the housing. The rotor has a main body which is secured to the drive shaft and is provided with conveying blades for the medium. The rotor has a turbine or pump operating counter to the transporting or conveying direction of the conveying blades. At least one passage is arranged in the main body and extends from the pressure side to the suction side of the rotor, with the passage being connected with a suction gap on the inner tube.

    摘要翻译： 用于流体介质的泵，其中内管或管布置在壳体中。 驱动轴被安装在内管中，并且转子布置在壳体中。 转子具有固定在驱动轴上的主体，并具有用于介质的输送叶片。 转子具有与输送叶片的输送方向相反的涡轮机或泵。 至少一个通道布置在主体中并且从压力侧延伸到转子的吸入侧，通道与内管上的吸入间隙连接。

    Apparatus for the treatment of workpieces
    9.
    发明授权
    Apparatus for the treatment of workpieces 有权
    用于处理工件的设备

    公开(公告)号：US06725561B2

    公开(公告)日：2004-04-27

    申请号：US10348611

    申请日：2003-01-21

    申请人： Kersten Link ,  Wolfgang Renner

    发明人： Kersten Link ,  Wolfgang Renner

    IPC分类号： F26B1900

    CPC分类号： B05B13/0221 ,  B05B16/40 ,  B65G69/181

    摘要： An apparatus for treating workpieces comprises a treatment chamber enclosing a treatment zone for workpieces. A conveyor guides workpieces through the chamber. Said conveyor comprises drive elements located outside the chamber, and a carrier arm, extending through a slot along the conveyor's path of motion, in a wall of the chamber. A sealing arrangement comprises a first set of spring strips, which overlap laterally and are attached on one side of the slot to the wall, and an opposing second set of spring strips attached on the other side of the slot to the wall. In a resting position, the end zones of the spring strips overlap. Two deflecting devices, which move together with the carrier arm by the conveyor, open the sealing arrangement proximate the carrier arm by resiliently bending apart the spring strips. After passage of the carrier arm, the spring strips return to a sealing position.

    摘要翻译： 一种用于处理工件的设备包括一个封闭工件处理区的处理室。 输送机引导通过该室的工件。 所述输送机包括位于室外的驱动元件，以及承载臂，其沿着输送机的运动路径延伸穿过狭槽，在该室的壁中。 密封装置包括第一组弹簧条，其横向重叠并且被附接到所述槽的一侧与所述壁，以及相对的第二组弹簧条，所述另一组弹簧条附接在所述狭槽的另一侧与所述壁。 在静止位置，弹簧条的端部区域重叠。 通过输送机与承载臂一起移动的两个偏转装置通过弹性地分开弹簧条来打开靠近承载臂的密封装置。 在承载臂通过后，弹簧带返回到密封位置。