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公开(公告)号：US20210361548A1
公开(公告)日：2021-11-25
申请号：US16494342
申请日：2018-10-25
Applicant: Yimin Sun
Inventor： Yimin Sun
Abstract: The present invention relates to the synthesis of new classes of sunscreen agents, the usage of such sunscreen agents in sunscreen formulations aiming at reduction of sunscreen agents' skin penetration, and a formulation technology using existing sunscreen agents aiming at reduction of sunscreen agents' skin penetration, therefore improving the bio-safety of the sunscreen products.
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公开(公告)号：US20230263901A1
公开(公告)日：2023-08-24
申请号：US18040315
申请日：2021-01-29
Applicant: Yimin Sun
Inventor： Yimin Sun
IPC: A61K47/61
CPC classification number: A61K47/61
Abstract: The present invention relates to a mucus adhesion drug delivery technology. The technology involves the preparation of materials consisting of mucus adhesive excipient polymer chemically bonded with drug molecules and delivery of the materials with fast disintegration tablet with enteric coating to intestine. The bonding between the excipient polymer and the drug molecules is either ionic bonds, covalent bonds, or metal coordination bonds. The test of the mucus adhesion drug delivery technology was carried out using a dog model. The test data indicated successful retaining of drug molecules on the intestine mucus resulting in not only dramatic extension of drug release time, but also great improvement in the bioavailability of the API.
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Patent Agency Ranking
公开(公告)号：US08680016B2
公开(公告)日：2014-03-25
申请号：US11791157
申请日：2004-11-23
Applicant: Wei Shao , Yongchao Zhao , Yimin Sun , Jiying Qiao , Huajiang Wei , Weiping Yang , Yuxiang Zhou , Jing Cheng
Inventor： Wei Shao , Yongchao Zhao , Yimin Sun , Jiying Qiao , Huajiang Wei , Weiping Yang , Yuxiang Zhou , Jing Cheng
IPC: C40B20/02
CPC classification number: G01N33/54366 , C12Q1/6806 , C12Q1/6837 , C12Q2565/531 , C12Q2565/501 , C12Q2563/131
Abstract: A testing method of nucleic acid binding protein based on biochip, comprises the following steps: 1. puts a plurality of groups solution including nucleic acid captured probes into biological sample including a plurality of nucleic acid binding protein to be test, and thus forming nucleic acid captured probe-nucleic acid binding protein complexes; such nucleic acid captured probe includes at least a segment of binding sequence which can bind with aimed nucleic acid binding protein; 2. separates such nucleic acid captured probe-nucleic acid binding protein complexes, then recoveries nucleic acid captured probes; 3. hybridizes the nucleic acid captured probes according to step 2 with a plurality of single strand blotting probes on biochip substrate; the sequence of such blotting probe compensates with such nucleic acid captured probe or one of its strand; 4. detects the result of hybridization.
Abstract translation: 一种基于生物芯片的核酸结合蛋白的检测方法，包括以下步骤：1.将包含核酸捕获探针的多组溶液放入包括待测试的多种核酸结合蛋白的生物样品中，从而形成核酸 捕获的探针 - 核酸结合蛋白复合物; 此类核酸捕获的探针包括可与靶核酸结合蛋白结合的至少一段结合序列; 2.分离这些核酸捕获的探针 - 核酸结合蛋白复合物，然后回收核酸捕获的探针; 3.将根据步骤2的核酸捕获探针与生物芯片底物上的多个单链印迹探针杂交; 这种印迹探针的序列用这种核酸捕获的探针或其一条链补偿; 4.检测杂交结果。
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公开(公告)号：US20090018025A1
公开(公告)日：2009-01-15
申请号：US11791157
申请日：2004-11-23
Applicant: Wei Shao , Yongchao Zhao , Yimin Sun , Jiying Qiao , Huajiang Wei , Weiping Yang , Yuxiang Zhou , Jing Cheng
Inventor： Wei Shao , Yongchao Zhao , Yimin Sun , Jiying Qiao , Huajiang Wei , Weiping Yang , Yuxiang Zhou , Jing Cheng
IPC: C40B20/02
CPC classification number: G01N33/54366 , C12Q1/6806 , C12Q1/6837 , C12Q2565/531 , C12Q2565/501 , C12Q2563/131
Abstract: A testing method of nucleic acid binding protein based on biochip, comprises the following steps: 1. puts a plurality of groups solution including nucleic acid captured probes into biological sample including a plurality of nucleic acid binding protein to be test, and thus forming nucleic acid captured probe-nucleic acid binding protein complexes; such nucleic acid captured probe includes at least a segment of binding sequence which can bind with aimed nucleic acid binding protein; 2. separates such nucleic acid captured probe-nucleic acid binding protein complexes, then recoveries nucleic acid captured probes; 3. hybridizes the nucleic acid captured probes according to step 2 with a plurality of single strand blotting probes on biochip substrate; the sequence of such blotting probe compensates with such nucleic acid captured probe or one of its strand; 4. detects the result of hybridization.
Abstract translation: 一种基于生物芯片的核酸结合蛋白的检测方法，包括以下步骤：1.将包含核酸捕获探针的多组溶液放入包括待测试的多种核酸结合蛋白的生物样品中，从而形成核酸 捕获的探针 - 核酸结合蛋白复合物; 此类核酸捕获的探针包括可与靶核酸结合蛋白结合的至少一段结合序列; 2.分离这些核酸捕获的探针 - 核酸结合蛋白复合物，然后回收核酸捕获的探针; 3.将根据步骤2的核酸捕获探针与生物芯片底物上的多个单链印迹探针杂交; 这种印迹探针的序列用这种核酸捕获的探针或其一条链补偿; 4.检测杂交结果。
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公开(公告)号：US20230285258A1
公开(公告)日：2023-09-14
申请号：US16971675
申请日：2019-09-10
Applicant: Yimin Sun
Inventor： Yimin Sun
CPC classification number: A61K8/4966 , A61K8/36 , A61K8/411 , A61K8/8111 , A61Q17/04
Abstract: The present invention relates to the synthesis of new classes of sunscreen agents, the usage of such sunscreen agents to prepare sunscreen formulation materials aiming at reduction of sunscreen agents’ skin penetration. The whole purpose of this invention is to improve the biosafety of sunscreen products via our novel sunscreen materials and formulation technology to reduce or to eliminate skin penetration of sunscreen agents. The technology of this invention can be applied to cosmetics, pharmaceutical or insects’ repellant products.
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公开(公告)号：US11229590B2
公开(公告)日：2022-01-25
申请号：US16494342
申请日：2018-10-25
Applicant: Yimin Sun
Inventor： Yimin Sun
Abstract: The present invention relates to the synthesis of new classes of sunscreen agents, the usage of such sunscreen agents in sunscreen formulations aiming at reduction of sunscreen agents' skin penetration, and a formulation technology using existing sunscreen agents aiming at reduction of sunscreen agents' skin penetration, therefore improving the bio-safety of the sunscreen products.
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公开(公告)号：US20090137411A1
公开(公告)日：2009-05-28
申请号：US10593908
申请日：2005-03-28
Applicant: Yimin Sun , Wanli Xing , Guoqing Wang , Hongwu Du , Rong Zhang , Yuan Lu , Yan Wang , Jing Cheng
Inventor： Yimin Sun , Wanli Xing , Guoqing Wang , Hongwu Du , Rong Zhang , Yuan Lu , Yan Wang , Jing Cheng
CPC classification number: G01N33/543 , B01J2219/00387 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00659 , B01J2219/0072 , C40B60/14 , G01N33/54366
Abstract: The present invention discloses methods for detection of small molecule compounds and its specific biochips. Biochips of the present invention comprise a solid support and carrier-linked small molecules immobilized onto the solid support. The invention also provides methods and kits for detection of small molecule compounds using the biochips of the invention.
Abstract translation: 本发明公开了小分子化合物及其特定生物芯片的检测方法。 本发明的生物芯片包含固体支持物和固定在固体支持物上的载体连接的小分子。 本发明还提供了使用本发明的生物芯片检测小分子化合物的方法和试剂盒。
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