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公开(公告)号：US20180224360A1
公开(公告)日：2018-08-09
申请号：US15945228
申请日：2018-04-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
IPC: G01N1/40
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises diatomaceous earth bearing, on at least a portion of its surface, a surface treatment comprising a surface modifier comprising ferric oxide, titanium dioxide, fine-nanoscale gold or platinum, or a combination thereof; (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device.
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公开(公告)号：US20150132740A1
公开(公告)日：2015-05-14
申请号：US14400390
申请日：2013-05-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Evan Koon Lun Yuuji Hajime , Andrew W. Rabins
IPC: G01N33/53 , G01N33/569
CPC classification number: G01N33/5306 , B01J20/0277 , B01J20/28026 , B01J20/28028 , C12N11/14 , C12Q1/04 , C12Q1/24 , G01N33/56916 , G01N33/56938 , G01N33/56961 , G01N2333/245 , G01N2333/395
Abstract: A concentration agent for microorganisms is provided that contains both lanthanum and carbonate. Additionally, articles that include the concentration agent and methods of concentrating a microorganism using the concentration agent are provided.
Abstract translation: 提供含有镧和碳酸盐的微生物浓缩剂。 此外，提供了包含浓缩剂的物质和使用浓缩剂浓缩微生物的方法。
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公开(公告)号：US09784653B2
公开(公告)日：2017-10-10
申请号：US15018436
申请日：2016-02-08
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Wensheng Xia , Jon A. Kirschhoffer , Andrew W. Rabins
CPC classification number: G01N1/30 , B01L3/502 , B01L3/5023 , B01L3/50255 , B01L2200/026 , B01L2200/028 , B01L2200/10 , B01L2300/0681 , B01L2300/069 , B01L2300/0832 , B01L2300/0861 , B01L2300/0887 , B01L2400/049 , C12N15/1017 , G01N1/34
Abstract: A first apparatus for processing a liquid sample is disclosed. The apparatus includes a sample-receiving, a filtrate-receiving component, and an analyte-capture element. The apparatus forms a liquid flow path through which the sample passes, thereby causing the analyte-capture element to capture an analyte, if present. A method is disclosed whereby a liquid sample is passed through the first apparatus and the analyte-capture element is easily separated from the apparatus for further processing and detection of the analyte. A structurally-related second apparatus for processing a plurality of liquid samples, and a corresponding method of use, also is disclosed.
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公开(公告)号：US08459470B2
公开(公告)日：2013-06-11
申请号：US13708653
申请日：2012-12-07
Applicant: 3M Innovative Properties Company
Inventor： Douglas E. Weiss , Clinton P. Waller, Jr. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
CPC classification number: B01D39/163 , C08F255/00 , C08F289/00 , C08F291/00 , C08L51/08 , C08L2666/02
Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.
Abstract translation: 公开了接枝非织造基材，其平均纤维尺寸为0.7-15微米，空隙体积为50至95％，以及包含接枝到非织造基材表面的阳离子氨基烷基（甲基）丙烯酰基单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物纯化或分离靶物质，例如寡核苷酸或单克隆抗体（MAb）。
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公开(公告)号：US20130092620A1
公开(公告)日：2013-04-18
申请号：US13708653
申请日：2012-12-07
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Douglas E. Weiss , Clinton P. Waller, JR. , Michael R. Berrigan , Andrew W. Rabins , Jeffrey A. Lucas , Kannan Seshadri , Catherine A. Bothof
IPC: B01D39/16
CPC classification number: B01D39/163 , C08F255/00 , C08F289/00 , C08F291/00 , C08L51/08 , C08L2666/02
Abstract: A grafted nonwoven substrate is disclosed having average fiber sizes of 0.7 to 15 microns, and a void volume of 50 to 95%, and a polymer comprising cationic aminoalkyl(meth)acryloyl monomer units grafted to the surface of the nonwoven substrate. The article may be used as a filter element to purify or separate target materials, such as oligonucleotides or monoclonal antibodies (MAb), from a fluid mixture.
Abstract translation: 公开了接枝非织造基材，其平均纤维尺寸为0.7-15微米，空隙体积为50至95％，以及包含接枝到非织造基材表面的阳离子氨基烷基（甲基）丙烯酰基单体单元的聚合物。 该制品可以用作过滤元件以从流体混合物纯化或分离靶物质，例如寡核苷酸或单克隆抗体（MAb）。
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Patent Agency Ranking
公开(公告)号：US10240018B2
公开(公告)日：2019-03-26
申请号：US14602603
申请日：2015-01-22
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device.
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公开(公告)号：US20180312939A1
公开(公告)日：2018-11-01
申请号：US15770060
申请日：2016-10-18
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Michael J. Sierakowski , Andrew W. Rabins , Karl D. Weilandt , Clinton P. Waller, Jr. , Mikhail A. Belkin , Susannah C. Clear , Tien Yi T.H. Whiting
CPC classification number: B01D17/045 , B01D17/0208 , B01D17/048 , C22B3/0005 , C22B3/0017 , C22B3/24 , Y02P10/234
Abstract: Provided are methods and related compositions for separating immiscible organic and aqueous compositions. The methods include dispersing a discrete, insoluble filler in the organic composition, dispersing the organic composition into the aqueous composition, separating under gravity the organic and aqueous compositions into respective upper and lower layers. Advantageously, the insoluble filler remains in the organic composition and facilitates segregation and coalescence of droplets of the organic composition in the aqueous composition.
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公开(公告)号：US20180128722A1
公开(公告)日：2018-05-10
申请号：US15849830
申请日：2017-12-21
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising (1) a porous fibrous nonwoven matrix and (2) a plurality of particles of at least one concentration agent that comprises a metal silicate, the particles being enmeshed in the porous fibrous nonwoven matrix; (b) providing a sample comprising at least one target cellular analyte; (c) contacting the concentration device with the sample such that at least a portion of the at least one target cellular analyte is bound to or captured by the concentration device; and (d) detecting the presence of at least one bound target cellular analyte.
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公开(公告)号：US20150133574A1
公开(公告)日：2015-05-14
申请号：US14602603
申请日：2015-01-22
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Andrew W. Rabins
IPC: C08J9/00
CPC classification number: C08J9/0066 , B01D61/147 , B01D63/00 , C08J9/0061 , C08J2323/06 , C08J2423/06 , C12Q1/24
Abstract: A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one concentration agent that comprises an amorphous metal silicate and that has a surface composition having a metal atom to silicon atom ratio of less than or equal to 0.5, as determined by X-ray photoelectron spectroscopy (XPS); (b) providing a sample comprising at least one microorganism strain; and (c) contacting the concentration device with the sample such that at least a portion of the at least one microorganism strain is bound to or captured by the concentration device.
Abstract translation: 用于捕获或浓缩用于检测或测定的微生物的方法包括（a）提供包含烧结的多孔聚合物基质的浓缩装置，所述多孔聚合物基质包含至少一种浓缩剂，所述浓缩剂包含无定形金属硅酸盐，并且具有具有金属原子与硅原子的表面组成 比例小于或等于0.5，如通过X射线光电子能谱（XPS）测定的; （b）提供包含至少一种微生物菌株的样品; 和（c）使浓缩装置与样品接触，使得至少一部分微生物菌株与浓缩装置结合或捕获。
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公开(公告)号：US20150079582A1
公开(公告)日：2015-03-19
申请号：US14391904
申请日：2013-03-04
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Manjiri T. Kshirsagar , Evan Koon Lun Yuuji Hajime , Andrew W. Rabins
Abstract: A bismuth-containing concentration agent for microorganisms is provided. Additionally, articles that include the concentration agent and methods of concentrating a microorganism using the concentration agent are provided.
Abstract translation: 提供了一种含铋微生物浓缩剂。 此外，提供了包含浓缩剂的物质和使用浓缩剂浓缩微生物的方法。
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