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公开(公告)号：US09750622B2
公开(公告)日：2017-09-05
申请号：US14307440
申请日：2014-06-17
CPC分类号： A61F2/90 , A61F2/91 , A61L31/041 , A61L31/06 , A61L31/148
摘要： Bioresorbable polymer vascular scaffolds made of combinations of polylactide and polycaprolactone having a high molecular weight polymer, thin struts in a selected range and sufficient radial strength to support a vessel upon deployment. The scaffolds have degradation behavior of molecular weight, radial strength, and mass that are conducive to healing of a vessel including providing patency to a vessel, reduction of radial strength, breaking up, and resorbing to allow return of the vessel to a natural state.
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2.发明申请HIGH MOLECULAR WEIGHT POLYLACTIDE AND POLYCAPROLACTONE COPOLYMER AND BLENDS FOR BIORESORBABLE VASCULAR SCAFFOLDS 有权高分子量聚合物和聚碳酸酯共聚物和可生物降解血管的混合物公开(公告)号：US20150359648A1
公开(公告)日：2015-12-17
申请号：US14307440
申请日：2014-06-17
CPC分类号： A61F2/90 , A61F2/91 , A61L31/041 , A61L31/06 , A61L31/148
摘要： Bioresorbable polymer vascular scaffolds made of combinations of polylactide and polycaprolactone having a high molecular weight polymer, thin struts in a selected range and sufficient radial strength to support a vessel upon deployment. The scaffolds have degradation behavior of molecular weight, radial strength, and mass that are conducive to healing of a vessel including providing patency to a vessel, reduction of radial strength, breaking up, and resorbing to allow return of the vessel to a natural state.
摘要翻译： 由具有高分子量聚合物的聚丙交酯和聚己内酯的组合制成的可生物再吸收的聚合物血管支架，在选定范围内的薄支柱和足够的径向强度以在部署时支撑血管。 支架具有有助于血管愈合的分子量，径向强度和质量的降解行为，包括向容器提供通畅性，降低径向强度，分解和再吸收以允许血管返回到自然状态。
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公开(公告)号：US09125763B2
公开(公告)日：2015-09-08
申请号：US13840185
申请日：2013-03-15
发明人： Karen J. Wang , Edward P. Garcia , Manish Gada , Marc Schraner , Michael Green , Stan Lam
CPC分类号： A61F2/958 , A61F2/06 , A61F2/95 , A61F2002/9522 , B21D37/18 , B21D39/048 , B21D41/04 , B23P17/04
摘要： A stent crimping tool insert comprises a core body configured for insertion into and removal from within a crimping chamber of a stent crimping tool. The core body has a core surface configured to withstand a compressive force without a reduction in diameter of the core surface.
摘要翻译： 支架压接工具插入件包括构造成用于插入到支架压接工具的压接室内并从其移除的芯体。 芯体具有被构造为承受压缩力而不减小芯表面直径的芯表面。
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公开(公告)号：US20130187313A1
公开(公告)日：2013-07-25
申请号：US13734879
申请日：2013-01-04
发明人： Thierry Glauser , Vincent Gueriguian , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth
CPC分类号： B29D22/00 , A61F2/91 , B29C49/0005 , B29C49/02 , B29C49/04 , B29C49/08 , B29C49/78 , B29C55/26 , B29C2793/009 , B29K2995/004 , B29K2995/0041 , B29K2995/0046 , B29K2995/0056 , B29K2995/006 , B29K2995/0077 , B29K2995/0089 , B29L2031/7542
摘要： Methods to expand polymer tubing with desirable or optimum morphology and mechanical properties for stem manufacture and fabrication of a stent therefrom are disclosed.
摘要翻译： 公开了扩展聚合物管的方法，其具有用于茎的制造和制造支架的所需或最佳形态和机械性能。
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公开(公告)号：US10213949B2
公开(公告)日：2019-02-26
申请号：US14852135
申请日：2015-09-11
发明人： Bethany Steichen , Stephen Pacetti , Manish Gada , Thierry Glauser , Lothar Kleiner , Yunbing Wang , James Oberhauser , Ni Ding
摘要： Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
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公开(公告)号：US09510964B2
公开(公告)日：2016-12-06
申请号：US14819228
申请日：2015-08-05
发明人： Karen J. Wang , Edward P. Garcia , Manish Gada , Marc Schraner , Michael Green , Stan Lam
CPC分类号： A61F2/958 , A61F2/06 , A61F2/95 , A61F2002/9522 , B21D37/18 , B21D39/048 , B21D41/04 , B23P17/04
摘要： A stent crimping tool insert comprises a core body configured for insertion into and removal from within a crimping chamber of a stent crimping tool. The core body has a core surface configured to withstand a compressive force without a reduction in diameter of the core surface.
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公开(公告)号：US20160157988A1
公开(公告)日：2016-06-09
申请号：US15042045
申请日：2016-02-11
发明人： Yunbing Wang , James Oberhauser , Manish Gada
CPC分类号： A61F2/06 , A61L31/041 , A61L31/129 , A61L31/148 , A61L31/16 , A61L2300/422 , C08L67/04
摘要： A medical device implantable within a peripheral vessel of the body composed of a bioresorbable polymer is disclosed. The device has a high resistance to fracture, is very flexible, and has a high crush recovery when subjected to crushing, axial, or torsional forces.
摘要翻译： 公开了一种可植入在由生物可再吸收的聚合物组成的身体的外周血管内的医疗装置。 该装置具有高抗断裂性，非常柔软，并且当受到破碎，轴向或扭转力时具有高的压碎恢复性。
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8.发明申请CONTROLLING MOISTURE IN AND PLASTICIZATION OF BIORESORBABLE POLYMER FOR MELT PROCESSING 审中-公开控制用于熔融加工的可生物降解聚合物的水分和塑化公开(公告)号：US20150375437A1
公开(公告)日：2015-12-31
申请号：US14852135
申请日：2015-09-11
发明人： Bethany Steichen , Stephen Pacetti , Manish Gada , Thierry Glauser , Lothar Kleiner , Yunbing Wang , James Oberhauser , Ni Ding
IPC分类号： B29C47/00
CPC分类号： B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/0066 , B29C47/0869 , B29C47/0893 , B29C47/0894 , B29C47/1018 , B29C47/1027 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92333 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006
摘要： Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
摘要翻译： 公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。 进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。
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9.发明申请公开(公告)号：US20150359650A1
公开(公告)日：2015-12-17
申请号：US14819228
申请日：2015-08-05
发明人： Karen J. Wang , Edward P. Garcia , Manish Gada , Marc Schraner , Michael Green , Stan Lam
IPC分类号： A61F2/958
CPC分类号： A61F2/958 , A61F2/06 , A61F2/95 , A61F2002/9522 , B21D37/18 , B21D39/048 , B21D41/04 , B23P17/04
摘要： A stent crimping tool insert comprises a core body configured for insertion into and removal from within a crimping chamber of a stent crimping tool. The core body has a core surface configured to withstand a compressive force without a reduction in diameter of the core surface.
摘要翻译： 支架压接工具插入件包括构造成用于插入到支架压接工具的压接室内并从其移除的芯体。 芯体具有被构造为承受压缩力而不减小芯表面直径的芯表面。
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公开(公告)号：US20140277398A1
公开(公告)日：2014-09-18
申请号：US13802098
申请日：2013-03-13
发明人： Yunbing Wang , James Oberhauser , Manish Gada
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61L31/041 , A61L31/129 , A61L31/148 , A61L31/16 , A61L2300/422 , C08L67/04
摘要： A medical device implantable within a peripheral vessel of the body composed of a bioresorbable polymer is disclosed. The device has a high resistance to fracture, is very flexible, and has a high crush recovery when subjected to crushing, axial, or torsional forces.
摘要翻译： 公开了一种可植入在由生物可再吸收的聚合物组成的身体的外周血管内的医疗装置。 该装置具有高抗断裂性，非常柔软，并且当受到破碎，轴向或扭转力时具有高的压碎恢复性。
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