公开(公告)号：US20140066762A1

公开(公告)日：2014-03-06

申请号：US14016060

申请日：2013-08-31

Applicant: ACADEMIA SINICA

Inventor： Yeu-Kuang Hwu ,  Chia-Chi Chien ,  Cheng-Liang Wang

IPC: A61B6/00

CPC classification number: A61B6/485 ,  A61B6/481 ,  A61B6/508 ,  A61K49/0065 ,  B82Y5/00 ,  B82Y15/00

Abstract: A method of tracking specific cells in vivo is disclosed. The method of the disclosure includes: providing fluorescent nanoparticles suitable for targeting of specific cells; administering the fluorescent nanoparticles to a subject; providing an X-ray source to irradiate the subject; and determining the distribution and growth of the specific cells by the fluorescent images from the fluorescent nanoparticles and X-ray images of the subject irradiated by the X-ray source.

Abstract translation: 公开了一种在体内追踪特定细胞的方法。 本公开的方法包括：提供适于靶向特定细胞的荧光纳米颗粒; 向受试者施用荧光纳米颗粒; 提供X射线源以照射受试者; 以及通过来自荧光纳米颗粒的荧光图像和由X射线源照射的被摄体的X射线图像确定特定细胞的分布和生长。

公开(公告)号：US09884306B2

公开(公告)日：2018-02-06

申请号：US14324180

申请日：2014-07-05

Applicant: ACADEMIA SINICA

Inventor： Yeu-Kuang Hwu ,  Sheng-Feng Lai ,  Cheng-Liang Wang

IPC: B01J19/12 ,  B01J19/00 ,  B01J19/02 ,  B01J19/08 ,  B01J19/24 ,  B01J4/00

CPC classification number: B01J19/125 ,  B01J4/002 ,  B01J19/0093 ,  B01J19/02 ,  B01J19/082 ,  B01J19/2415 ,  B01J2219/00164 ,  B01J2219/00799 ,  B01J2219/00801 ,  B01J2219/00822 ,  B01J2219/00833 ,  B01J2219/00927 ,  B01J2219/00939 ,  B01J2219/00959 ,  B01J2219/0277 ,  B01J2219/0295 ,  B01J2219/0871 ,  B01J2219/0877

Abstract: A convection-free flow-type reactor includes a reactor body. The reactor body includes a reaction chamber to house a fluid. An inlet is in communication with the reaction chamber to allow input of a reactant fluid. An outlet is in communication with the reaction chamber to allow output of a product fluid. An energy beam source device provides an energy beam to irradiate the reactant fluid in the reaction chamber. The disclosure further provides a convection-free flow-type synthesis method.

公开(公告)号：US09662080B2

公开(公告)日：2017-05-30

申请号：US14016060

申请日：2013-08-31

Applicant: ACADEMIA SINICA

Inventor： Yeu-Kuang Hwu ,  Chia-Chi Chien ,  Cheng-Liang Wang

IPC: A61B5/05 ,  A61B6/00 ,  A61K49/00 ,  B82Y5/00 ,  B82Y15/00

CPC classification number: A61B6/485 ,  A61B6/481 ,  A61B6/508 ,  A61K49/0065 ,  B82Y5/00 ,  B82Y15/00

Abstract: A method of tracking specific cells in vivo is disclosed. The method of the disclosure includes: providing fluorescent nanoparticles suitable for targeting of specific cells; administering the fluorescent nanoparticles to a subject; providing an X-ray source to irradiate the subject; and determining the distribution and growth of the specific cells by the fluorescent images from the fluorescent nanoparticles and X-ray images of the subject irradiated by the X-ray source.