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公开(公告)号:US20200016057A1
公开(公告)日:2020-01-16
申请号:US16579122
申请日:2019-09-23
Applicant: Ajinomoto Co., Inc.
Inventor: Yoshinobu TAKINO , Sachise KARAKAWA , Fumie OKURA , Eri IKEGAMI
Abstract: Agents which contain at least one D-amino acid selected from the group consisting of D-asparagine, D-valine, D-allo-threonine, D-lysine, D-glutamine, D-histidine, D-leucine, D-phenylalanine, D-serine, D-tryptophan, and D-tyrosine are useful as whitening agents and are effective in preventing and inhibiting melanin pigmentation such as pigmented spot, freckles, and somberness.
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公开(公告)号:US20130095048A1
公开(公告)日:2013-04-18
申请号:US13686384
申请日:2012-11-27
Applicant: AJINOMOTO CO., INC.
Inventor: Yusuke AMINO , Yoshinobu TAKINO , Shinji KURODA , Keiji IWASAKI , Megumi KANEKO , Fumie OKURA
IPC: C07D277/06 , C07D513/08 , A61Q19/02 , A61Q17/00 , A61Q1/02 , A61Q15/00 , A61K8/49 , C07D417/04
CPC classification number: C07D277/06 , A61K8/49 , A61K8/4926 , A61Q1/02 , A61Q15/00 , A61Q17/00 , A61Q19/02 , C07D417/04 , C07D513/08 , C07K5/06139
Abstract: Cysteine compounds represented by the following formula wherein each symbol is as defined in the specification, and salts thereof, are superior in stability, have less odor, exhibit an eumelanin production suppressive effect, and are useful as cosmetic agents.
Abstract translation: 由下式表示的半胱氨酸化合物,其中每个符号如本说明书中所定义,及其盐的稳定性优异,具有较少的气味,显示出黑素素产生抑制作用,并且可用作化妆品。
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公开(公告)号:US20160060234A1
公开(公告)日:2016-03-03
申请号:US14934596
申请日:2015-11-06
Applicant: AJINOMOTO CO., INC.
Inventor: Yusuke AMINO , Yoshinobu TAKINO , Shinji KURODA , Keiji IWASAKI , Megumi KANEKO , Fumie OKURA
IPC: C07D277/06 , C07K5/078 , C07D417/04 , C07D513/08
CPC classification number: C07D277/06 , A61K8/49 , A61K8/4926 , A61Q1/02 , A61Q15/00 , A61Q17/00 , A61Q19/02 , C07D417/04 , C07D513/08 , C07K5/06139
Abstract: Cysteine compounds represented by the following formula wherein each symbol is as defined in the specification, and salts thereof, are superior in stability, have less odor, exhibit an eumelanin production suppressive effect, and are useful as cosmetic agents.
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公开(公告)号:US20140271510A1
公开(公告)日:2014-09-18
申请号:US14288791
申请日:2014-05-28
Applicant: AJINOMOTO CO., INC.
Inventor: Yoshinobu TAKINO , Fumie OKURA , Shinji KURODA
CPC classification number: A61K8/49 , A61K8/361 , A61K8/368 , A61K8/44 , A61K8/445 , A61K8/4973 , A61K8/498 , A61K8/602 , A61K8/64 , A61K8/97 , A61K31/426 , A61Q19/02
Abstract: Provided is a cosmetic agent superior in a whitening effect (including prophylaxis and removal of pigmented spot) and having high safety. In addition, a superior melanin production suppressive agent is provided.A cosmetic agent or melanin production suppressive agent comprising (A) a cysteine derivative represented by the formula (I) or a salt thereof: wherein X and Y are each independently OR1 or NHR2 wherein R1 and R2 are each independently a hydrogen atom or a C1-22 alkyl group; Z is a hydrogen atom or a C1-22 alkyl group; and W is a C1-22 alkyl group, a C1-22 alkoxy group or a C1-22 alkylamino group, and (B) a whitening agent.
Abstract translation: 本发明提供优异的美白效果(包括预防和去除色素斑点)并具有高安全性的美容剂。 此外,还提供了优异的黑色素生产抑制剂。 一种美容剂或黑素生成抑制剂,其包含(A)由式(I)表示的半胱氨酸衍生物或其盐:其中X和Y各自独立地为OR 1或NHR 2,其中R 1和R 2各自独立地为氢原子或C1 -22烷基; Z是氢原子或C 1-22烷基; W是C1-22烷基,C1-22烷氧基或C1-22烷基氨基,和(B)增白剂。
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公开(公告)号:US20140255327A1
公开(公告)日:2014-09-11
申请号:US14287899
申请日:2014-05-27
Applicant: AJINOMOTO CO. INC.
Inventor: Yusuke AMINO , Yoshinobu TAKINO , Satoru OHASHI , Fumie OKURA , Megumi KANEKO
CPC classification number: A61K8/492 , A61K8/42 , A61K8/49 , A61K31/4045 , A61Q19/02 , C07C235/34 , C07D209/14 , C07D209/20 , C07D209/32 , C07D405/12
Abstract: Compound represented by formula (I): wherein the symbols are as defined in the description, and salts thereof, are useful as skin whitening agents.
Abstract translation: 由式(I)表示的化合物:其中符号如说明书中所定义,及其盐可用作皮肤增白剂。
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