公开(公告)号：US09228215B2

公开(公告)日：2016-01-05

申请号：US14085171

申请日：2013-11-20

Applicant: AJINOMOTO CO., INC.

Inventor： Ryo Takeshita ,  Naoki Kadotani ,  Kenji Abe

IPC: C12P13/22 ,  C12P13/04 ,  C12P13/08 ,  C12P19/34 ,  C12N1/20 ,  C12N9/24 ,  C07H21/04 ,  C07K1/00 ,  C12N9/12

CPC classification number: C12P13/08 ,  C12N9/1205 ,  C12N9/2402 ,  C12P13/22 ,  C12Y302/0101

Abstract: A method is described for producing a target substance utilizing a microorganism by culturing the microorganism in a medium to produce and accumulate the target substance in the medium, and then collecting the target substance from culture. The microorganism is imparted with isomaltase activity, or modified to increase isomaltase activity.

公开(公告)号：US20190161780A1

公开(公告)日：2019-05-30

申请号：US16268082

申请日：2019-02-05

Applicant: AJINOMOTO CO., INC.

Inventor： Kazuteru Yamada ,  Ye Zhang ,  Kenji Abe ,  Naoki Iwanaga ,  Ryo Takeshita ,  Yuri Uehara ,  Chika Hikichi ,  Yasuhiro Oota

IPC: C12P13/08 ,  C12P13/04 ,  C12P13/20 ,  C12P13/14 ,  C12N1/20 ,  A23K50/80 ,  A23K10/18 ,  A01K61/10 ,  A01K61/59

Abstract: A method for producing an L-amino acid such as L-lysine is provided. An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a carotenoid biosynthesis enzyme is increased, in a medium, and collecting the L-amino acid from the medium.

公开(公告)号：US20140080185A1

公开(公告)日：2014-03-20

申请号：US14085171

申请日：2013-11-20

Applicant: AJINOMOTO CO., INC.

Inventor： Ryo Takeshita ,  Naoki Kadotani ,  Kenji Abe

IPC: C12P13/08

CPC classification number: C12P13/08 ,  C12N9/1205 ,  C12N9/2402 ,  C12P13/22 ,  C12Y302/0101

Abstract: A method is described for producing a target substance utilizing a microorganism by culturing the microorganism in a medium to produce and accumulate the target substance in the medium, and then collecting the target substance from culture. The microorganism is imparted with isomaltase activity, or modified to increase isomaltase activity.

Abstract translation: 描述了一种用于通过在培养基中培养微生物来生产和利用微生物的目标物质生产和累积目标物质的方法，然后从培养物中收集目标物质。 赋予微生物异麦芽糖酶活性，或修饰以增加异麦芽糖酶活性。

公开(公告)号：US11198894B2

公开(公告)日：2021-12-14

申请号：US16268082

申请日：2019-02-05

Applicant: AJINOMOTO CO., INC.

Inventor： Kazuteru Yamada ,  Ye Zhang ,  Kenji Abe ,  Naoki Iwanaga ,  Ryo Takeshita ,  Yuri Uehara ,  Chika Hikichi ,  Yasuhiro Oota

IPC: C12P13/20 ,  C12P13/08 ,  C12P13/04 ,  C12N15/09 ,  A23K50/80 ,  A23K10/18 ,  A01K61/10 ,  A01K61/59 ,  C12N1/20 ,  C12P13/14

Abstract: A method for producing an L-amino acid such as L-lysine is provided. An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a carotenoid biosynthesis enzyme is increased, in a medium, and collecting the L-amino acid from the medium.