公开(公告)号：US20180051250A1

公开(公告)日：2018-02-22

申请号：US15718574

申请日：2017-09-28

Applicant: AJINOMOTO CO., INC.

Inventor： Takuya MATSUMOTO ,  Sho SENDA ,  Tsuyoshi KOBAYASHI ,  Akihiro ARAKAWA

IPC: C12N5/0797

CPC classification number: C12N5/0623 ,  A61K35/30 ,  A61L27/00 ,  C12N5/10 ,  C12N2500/24 ,  C12N2500/46 ,  C12N2501/115 ,  C12N2506/03 ,  C12N2506/45

Abstract: Culture media, which contain chelated iron, promote cell proliferation of neural stem cells and/or neural progenitor cells while maintaining undifferentiated state and multipotency.

公开(公告)号：US20210284971A1

公开(公告)日：2021-09-16

申请号：US17213839

申请日：2021-03-26

Applicant: AJINOMOTO CO., INC.

Inventor： Takuya MATSUMOTO ,  Shimpei OGAWA ,  Shumpei FUROMITSU ,  Yusuke OHYA ,  Kotoe KOSEKI ,  Takuya HIGUCHI ,  Megumi NISHIYAMA

IPC: C12N5/074 ,  C12N5/0735

Abstract: By using an additive for culturing animal cells that contains an amino acid or glucose, or an amino acid and glucose; or a medium for culturing animal cells that contains an amino acid or glucose, or an amino acid and glucose in addition to a medium component; or a method for culturing animal cells that includes culturing the animal cells using the aforementioned medium, or adding the aforementioned additive to a culture, the proliferation ability of animal cells can be improved particularly when the animal cells are cultured using a serum-free medium or a low albumin medium.

公开(公告)号：US20170009200A1

公开(公告)日：2017-01-12

申请号：US15275586

申请日：2016-09-26

Applicant: AJINOMOTO CO., INC.

Inventor： Yoko KURIYAMA ,  Satoru OKAMOTO ,  Manabu KITAZAWA ,  Nao SUGIMOTO ,  Takuya MATSUMOTO

IPC: C12N5/00 ,  C12N5/074

CPC classification number: C12N5/0018 ,  C12N5/0696 ,  C12N2500/50 ,  C12N2501/998

Abstract: Culture media which contain a water-soluble polymer, such as polyvinyl alcohol and the like, and albumin, and the like, are useful for the proliferation of stem cells, and show good culture results, particularly with iPS cells, and maintain the stability of the medium properties, as well as using a reduced amount of albumin.

Abstract translation: 含有水溶性聚合物如聚乙烯醇等的培养基和白蛋白等可用于干细胞的增殖，并且显示出良好的培养结果，特别是对于iPS细胞，并保持稳定性 中等特性，以及使用减少量的白蛋白。

公开(公告)号：US20190024047A1

公开(公告)日：2019-01-24

申请号：US16144187

申请日：2018-09-27

Applicant: AJINOMOTO CO., INC.

Inventor： Takuya MATSUMOTO ,  Ikue HARATA ,  Sho SENDA

IPC: C12N5/0793 ,  C12N5/0797

Abstract: Media which are substantially free of one or more amino acids selected from the group consisting of L-glutamine, L-asparagine, and L-aspartic acid are useful for producing a neural stem cell and/or a neural progenitor cell with promoted neuronal differentiation potency.

公开(公告)号：US20180016554A1

公开(公告)日：2018-01-18

申请号：US15718445

申请日：2017-09-28

Applicant: AJINOMOTO CO., INC.

Inventor： Takuya MATSUMOTO ,  Sho SENDA ,  Tsuyoshi KOBAYASHI

IPC: C12N5/0797

CPC classification number: C12N5/0623 ,  C12N2500/36 ,  C12N2500/50 ,  C12N2500/90 ,  C12N2501/115

Abstract: A medium, which contains human serum albumin, is useful for proliferating neural stem cells and/or neural progenitor cells.