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    REAL TIME PEAK INTEGRATION FOR POOL COLLECTION CRITERIA VIA CHROMATOGRAPHIC AREA UNDER THE CURVE
    3.
    发明公开
    REAL TIME PEAK INTEGRATION FOR POOL COLLECTION CRITERIA VIA CHROMATOGRAPHIC AREA UNDER THE CURVE 审中-公开

    公开(公告)号：US20240316478A1

    公开(公告)日：2024-09-26

    申请号：US18579598

    申请日：2022-07-15

    Applicant: AMGEN INC.

    Inventor： Erik E. Zinn ,  Diana Woehle ,  Cassidy Maly ,  Xuejun Han ,  Kylee Celine Quitayen

    IPC: B01D15/42 ,  G01N30/86 ,  G01N30/88

    CPC classification number: B01D15/424 ,  G01N30/8631 ,  G01N30/88 ,  G01N2030/8804

    Abstract: A elution product yield improvement system includes a processor, an estimation model and an elution controller application including instructions configured, when executed by the processors, to receive initialization data; instantiate a communication link to a remote process/automation system; determine collection criteria; initiate collection; read data values; computing an area ratio via the estimation model; and cease collection. A computer-implemented method for improving elution yield and purity includes receiving initialization data; instantiating a communication link to a remote process/automation system; determining collection criteria; initiating collection; reading data values; computing an area ratio; and ceasing collection. A non-transitory computer readable medium includes program instructions that when executed, cause a computer to receive initialization data; instantiate a communication link to a remote process/automation system; determine collection criteria; initiate collection; read data values; computing an area ratio via the estimation model; and cease collection.

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