公开(公告)号：US20230363997A1

公开(公告)日：2023-11-16

申请号：US18153467

申请日：2023-01-12

Applicant: AMOREPACIFIC CORPORATION

Inventor： Euidong SON ,  Insup KIL ,  Si Young CHO ,  Wonseok PARK ,  Yong Deog HONG

IPC: A61K8/49 ,  A61Q19/00

CPC classification number: A61K8/498 ,  A61Q19/005 ,  A61Q19/004

Abstract: The disclosure relates to the method for alleviating skin irritation or inhibiting sebum production, which includes administering a composition including a compound represented by Chemical Formula 1, a salt thereof, a stereoisomer thereof, a hydrate thereof, or a solvate thereof as an active ingredient to a subject in need of alleviating skin irritation or inhibiting sebum production, and specifically the composition can alleviate the irritation of the skin stimulated by ultraviolet rays, and more specifically, the composition can alleviate the skin irritation by reducing inflammatory factors in the cells of the skin stimulated by simultaneous stimulation of UVA and UVB ultraviolet rays, and in addition, specifically, it is possible to suppress the sebum production by inhibiting intracellular lipid synthesis with the composition, and more specifically, the sebum production of the skin can be suppressed by reducing the expression level of the factors related to intracellular lipid synthesis with the composition.

公开(公告)号：US20210393496A1

公开(公告)日：2021-12-23

申请号：US17284643

申请日：2019-10-10

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Jeong CHOI ,  Young Gyu KANG ,  Jihyun KIM ,  Euidong SON ,  Gayoung CHO ,  Sowoong CHOI ,  Hyoung June KIM ,  Tae Ryong LEE

IPC: A61K8/49 ,  A61Q19/00

Abstract: Provided are a composition including coumestrol extracted from soybeans as an active ingredient, and a method of inhibiting cortisone reductase by applying it to skin of a subject.

公开(公告)号：US20220241168A1

公开(公告)日：2022-08-04

申请号：US17589202

申请日：2022-01-31

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyung Su KIM ,  Si Young CHO ,  Young Gyu KANG ,  Hyuk KIM ,  Euidong SON

IPC: A61K8/42 ,  A61Q7/00 ,  A61Q19/04 ,  A61Q19/00 ,  A23L33/00 ,  A23L33/10

Abstract: A composition includes, as an active ingredient, a substance capable of providing a useful effect to the skin by stimulating production of beta (β)-endorphin. The composition containing, as an active ingredient, sanshool, an isomer thereof, a hydrate thereof, or a solvate thereof stimulates production of β-endorphin when applied into the body, thereby providing useful effects to the skin, such as relieving skin irritation from the outside and providing a skin soothing effect.

公开(公告)号：US20220000816A1

公开(公告)日：2022-01-06

申请号：US17285750

申请日：2019-10-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Jeong CHOI ,  Euidong SON ,  Young Gyu KANG ,  Hyoung June KIM ,  Tae Ryong LEE

IPC: A61K31/192 ,  A61K9/00 ,  A61K36/15

Abstract: Provided are a composition including a compound of the following chemical formula as an active ingredient and a method of inhibiting a cortisone reductase by applying the same:

公开(公告)号：US20210353658A1

公开(公告)日：2021-11-18

申请号：US17284252

申请日：2019-10-10

Applicant: Amorepacific Corporation

Inventor： Eun Jeong CHOI ,  Euidong SON ,  Young Gyu KANG ,  Hyoung June KIM ,  Tae Ryong LEE

IPC: A61K31/7008 ,  A61K8/60 ,  A61Q19/00

Abstract: Provided is a composition for inhibiting cortisone reductase, including a compound represented by a specific chemical formula as an active ingredient.

公开(公告)号：US20210338555A1

公开(公告)日：2021-11-04

申请号：US17285801

申请日：2019-10-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun Jeong CHOI ,  Euidong SON ,  Young Gyu KANG ,  Hyoung June KIM ,  Tae Ryong LEE

IPC: A61K8/49 ,  A61Q19/00

Abstract: Provided are a composition including a compound represented by a specific chemical formula as an active ingredient and a method of inhibiting a cortisone reductase by applying the same to skin of a subject.