公开(公告)号：US11168357B2

公开(公告)日：2021-11-09

申请号：US16303647

申请日：2017-05-24

申请人： Atila Biosystems, Inc.

发明人： Youxiang Wang ,  Xin Chen ,  Rong Wang ,  Zhijie Yang ,  Yu Zhao

IPC分类号： C12Q1/6818 ,  C12Q1/6844 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6853 ,  C12Q1/686

摘要： The present disclosure provides compositions, methods and kits for Omega amplification technologies. In addition, the present disclosure provides compositions, methods and kits for universal FQ probe and for G-quadruplex detection methods for use in isothermal amplification technologies.

公开(公告)号：US20180148775A1

公开(公告)日：2018-05-31

申请号：US15569080

申请日：2016-04-22

申请人： ATILA BIOSYSTEMS, INC.

发明人： Youxiang Wang ,  Zhijie Yang ,  Xin Chen

IPC分类号： C12Q1/6848

CPC分类号： C12Q1/6848 ,  C12Q2525/101 ,  C12Q2531/113 ,  C12Q2537/157 ,  C12Q2537/159

摘要： The invention provides methods of amplification from a single primer or a pair of forward and reverse primers of limited nucleotide composition. Limited nucleotide composition means that the primers are underrepresented in at least one nucleotide type. Such primers have much reduced capacity to prime from each other or to extend initiated by mispriming from other than at their intended primer binding sites in a target nucleic acid.