公开(公告)号：US20220017950A1

公开(公告)日：2022-01-20

申请号：US17494561

申请日：2021-10-05

申请人： Atila Biosystems, Inc.

发明人： Youxiang WANG ,  Xin CHEN ,  Rong WANG ,  Zhijie YANG ,  Yu ZHAO

IPC分类号： C12Q1/6818 ,  C12Q1/6844 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6853 ,  C12Q1/686

摘要： The present disclosure provides compositions, methods and kits for Omega amplification technologies. In addition, the present disclosure provides compositions, methods and kits for universal FQ probe and for G-quadruplex detection methods for use in isothermal amplification technologies.

公开(公告)号：US20190187054A1

公开(公告)日：2019-06-20

申请号：US16323244

申请日：2017-08-09

申请人： ATILA BIOSYSTEMS, INC. ,  SYNERGISTIC DETECTOR DESIGNS, LLC

发明人： Arthur H. ROGERS ,  James T. ALCIVAR

IPC分类号： G01N21/64 ,  G01N21/03

CPC分类号： G01N21/6452 ,  G01N21/0332 ,  G01N21/6456 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2021/6419 ,  G01N2201/0627

摘要： Various embodiments are directed to a fluorescence reader for assessing a fluorescence intensity of one or more substance samples. The fluorescence reader may comprise a sample support structure for accepting sample wells containing corresponding samples therein, an illumination structure positioned below the sample support structure and configured to illuminate one or more samples positioned within the sample wells, and an imaging structure positioned above the sample support structure and configured to detect a fluorescence emitted by the one or more samples. The illumination structure may comprise one or more reflective perimeter walls, together with the support structure, defining an enclosed illumination cavity, and one or more light sources positioned within the enclosed illumination cavity and configured to emit light causing the one or more samples to fluoresce.

公开(公告)号：US11168357B2

公开(公告)日：2021-11-09

申请号：US16303647

申请日：2017-05-24

申请人： Atila Biosystems, Inc.

发明人： Youxiang Wang ,  Xin Chen ,  Rong Wang ,  Zhijie Yang ,  Yu Zhao

IPC分类号： C12Q1/6818 ,  C12Q1/6844 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6853 ,  C12Q1/686

摘要： The present disclosure provides compositions, methods and kits for Omega amplification technologies. In addition, the present disclosure provides compositions, methods and kits for universal FQ probe and for G-quadruplex detection methods for use in isothermal amplification technologies.

公开(公告)号：US20190203271A1

公开(公告)日：2019-07-04

申请号：US16303647

申请日：2017-05-24

申请人： Atila Biosystems, Inc.

发明人： Youxiang WANG ,  Xin CHEN ,  Rong WANG ,  Zhijie YANG ,  Yu ZHAO

IPC分类号： C12Q1/6818 ,  C12Q1/6844 ,  C12Q1/6853 ,  C12Q1/686 ,  C12Q1/6806

CPC分类号： C12Q1/6818 ,  C12N2310/16 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6846 ,  C12Q1/6853 ,  C12Q1/686 ,  C12Q2525/205 ,  C12Q2525/301 ,  C12Q2531/119 ,  C12Q2537/143 ,  C12Q2561/109 ,  C12Q2565/1015

摘要： The present disclosure provides compositions, methods and kits for Omega amplification technologies. In addition, the present disclosure provides compositions, methods and kits for universal FQ probe and for G-quadruplex detection methods for use in isothermal amplification technologies.

公开(公告)号：US20180148775A1

公开(公告)日：2018-05-31

申请号：US15569080

申请日：2016-04-22

申请人： ATILA BIOSYSTEMS, INC.

发明人： Youxiang Wang ,  Zhijie Yang ,  Xin Chen

IPC分类号： C12Q1/6848

CPC分类号： C12Q1/6848 ,  C12Q2525/101 ,  C12Q2531/113 ,  C12Q2537/157 ,  C12Q2537/159

摘要： The invention provides methods of amplification from a single primer or a pair of forward and reverse primers of limited nucleotide composition. Limited nucleotide composition means that the primers are underrepresented in at least one nucleotide type. Such primers have much reduced capacity to prime from each other or to extend initiated by mispriming from other than at their intended primer binding sites in a target nucleic acid.