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公开(公告)号：US20190185897A1
公开(公告)日：2019-06-20
申请号：US16042037
申请日：2018-07-23
Applicant: AbbVie Inc.
Inventor： Patrick Hossler , Sean McDermott , Christopher Racicot , Ivan Correia
CPC classification number: C12P21/005 , C07K16/00 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/60 , C07K2317/732 , C12N5/0018 , C12N2500/34
Abstract: The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of proteins expressed in host cells.
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2.发明申请公开(公告)号：US20170226552A1
公开(公告)日：2017-08-10
申请号：US15320522
申请日：2015-07-01
Applicant: AbbVie Inc.
Inventor： Patrick Hossler , Christopher Racicot , Sean McDermott
CPC classification number: C12P21/005 , C07K16/00 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/55 , C07K2317/64 , C12N1/38 , C12P21/00
Abstract: The present invention relates to the field of protein production and, in particular, to methods and compositions for modulating the glycosylation of recombinant proteins expressed in host cells using cell culture media supplemented with cobalt.
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公开(公告)号：US20170247445A1
公开(公告)日：2017-08-31
申请号：US15429780
申请日：2017-02-10
Applicant: AbbVie Inc.
Inventor： Sean McDermott , Patrick Hossler
CPC classification number: C07K16/241 , C07K16/00 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/90 , C12N5/0018 , C12N2500/36 , C12N2500/50 , C12N2510/02
Abstract: The present invention provides methods for increasing cell culture performance through the use of chemically defined feed media (CDFM). In particular, the present invention provides methods for the use of surfactants as supplements to CDFM to allow for higher concentrations of media components and thereby result in increased cell culture performance.
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Patent Agency Ranking
4.发明申请METHODS FOR MODULATING PROTEIN GLYCOSYLATION PROFILES OF RECOMBINANT PROTEIN THERAPEUTICS USING MONOSACCHARIDES AND OLIGOSACCHARIDES 有权使用单加糖和低聚糖调节重组蛋白质治疗药物蛋白质糖蛋白的方法公开(公告)号：US20140271632A1
公开(公告)日：2014-09-18
申请号：US14209821
申请日：2014-03-13
Applicant: AbbVie, Inc.
Inventor： Patrick Hossler , Sean McDermott , Christopher Racicot , Ivan Correia
IPC: C07K16/24
CPC classification number: C12P21/005 , C07K16/00 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/60 , C07K2317/732 , C12N5/0018 , C12N2500/34
Abstract: The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of proteins expressed in host cells.
Abstract translation: 本发明涉及蛋白质生产领域，特别涉及调节在宿主细胞中表达的蛋白质糖基化的方法和组合物。
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公开(公告)号：US20170355760A1
公开(公告)日：2017-12-14
申请号：US15588211
申请日：2017-05-05
Applicant: AbbVie Inc.
Inventor： Patrick Hossler , Sean McDermott , Christopher Racicot , Joseph G. Matuck , Keith Cochran , Christopher M. Chumsae
CPC classification number: C07K16/241 , C07K16/00 , C07K2317/14 , C07K2317/24 , C07K2317/41 , C12N5/0037 , C12N2500/34 , C12N2510/02 , C12P21/005
Abstract: The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of recombinant proteins expressed in host cells.
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公开(公告)号：US20170137860A1
公开(公告)日：2017-05-18
申请号：US15343549
申请日：2016-11-04
Applicant: AbbVie Inc.
Inventor： Patrick Hossler , Sean McDermott , Christopher Racicot , Ivan Correia
CPC classification number: C12P21/005 , C07K16/00 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/60 , C07K2317/732 , C12N5/0018 , C12N2500/34
Abstract: The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of proteins expressed in host cells.
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7.发明授权公开(公告)号：US09499614B2
公开(公告)日：2016-11-22
申请号：US14209821
申请日：2014-03-13
Applicant: AbbVie, Inc.
Inventor： Patrick Hossler , Sean McDermott , Christopher Racicot , Ivan Correia
CPC classification number: C12P21/005 , C07K16/00 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/60 , C07K2317/732 , C12N5/0018 , C12N2500/34
Abstract: The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of proteins expressed in host cells.
Abstract translation: 本发明涉及蛋白质生产领域，特别涉及调节在宿主细胞中表达的蛋白质糖基化的方法和组合物。
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8.发明申请METHODS FOR MODULATING THE GLYCOSYLATION PROFILE OF RECOMBINANT PROTEINS USING SUGARS 审中-公开使用蔗糖调节重组蛋白质糖化曲线的方法公开(公告)号：US20160185848A1
公开(公告)日：2016-06-30
申请号：US14795838
申请日：2015-07-09
Applicant: ABBVIE INC.
Inventor： Patrick Hossler , Sean McDermott , Christopher Racicot , Joseph G. Matuck , Keith Cochran , Chris M. Chumsae
CPC classification number: C07K16/241 , C07K16/00 , C07K2317/14 , C07K2317/24 , C07K2317/41 , C12N5/0037 , C12N2500/34 , C12N2510/02 , C12P21/005
Abstract: The present invention relates to the field of protein production, and in particular to methods and compositions for modulating glycosylation of recombinant proteins expressed in host cells.
Abstract translation: 本发明涉及蛋白质生产领域，特别涉及用于调节在宿主细胞中表达的重组蛋白质糖基化的方法和组合物。
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