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23 条记录 (耗时 0.015 秒)

    Brown adipose tissue utilization through neuromodulation
    1.
    发明授权
    Brown adipose tissue utilization through neuromodulation 有权
    棕色脂肪组织利用通过神经调节

    公开(公告)号：US08340772B2

    公开(公告)日：2012-12-25

    申请号：US12774073

    申请日：2010-05-05

    申请人： Abhi Vase ,  Johann Neisz

    发明人： Abhi Vase ,  Johann Neisz

    IPC分类号： A61N1/34

    CPC分类号： A61N1/0551

    摘要： Methods and devices for improved neurostimulation to treat obesity. Some methods include measuring temperature increases in Brown Adipose Tissue (BAT) during intraoperative test stimulations to determine the proper nerve electrode placement for implantation. Methods can include determining the side of the patient having the most BAT, and stimulating preferentially on that right or left side. The BAT maybe used to burn fat by stimulating the sympathetic nervous system innervating the BAT deposits.

    摘要翻译： 改善神经刺激治疗肥胖症的方法和装置。 一些方法包括在术中测试刺激期间测量棕色脂肪组织（BAT）中的温度升高，以确定用于植入的适当的神经电极放置。 方法可以包括确定具有最多BAT的患者的侧面，并且优先地在该右侧或左侧刺激。 BAT可能通过刺激支配BAT沉积物的交感神经系统来燃烧脂肪。

    BROWN ADIPOSE TISSUE UTILIZATION THROUGH NEUROMODULATION
    2.
    发明申请
    BROWN ADIPOSE TISSUE UTILIZATION THROUGH NEUROMODULATION 有权
    通过神经修复的棕色ADIPOSE组织利用

    公开(公告)号：US20100312295A1

    公开(公告)日：2010-12-09

    申请号：US12774073

    申请日：2010-05-05

    申请人： Abhi Vase ,  Johann Neisz

    发明人： Abhi Vase ,  Johann Neisz

    IPC分类号： A61N1/36

    CPC分类号： A61N1/0551

    摘要： Methods and devices for improved neurostimulation to treat obesity. Some methods include measuring temperature increases in Brown Adipose Tissue (BAT) during intraoperative test stimulations to determine the proper nerve electrode placement for implantation. Methods can include determining the side of the patient having the most BAT, and stimulating preferentially on that right or left side. The BAT maybe used to burn fat by stimulating the sympathetic nervous system innervating the BAT deposits.

    摘要翻译： 改善神经刺激治疗肥胖症的方法和装置。 一些方法包括在术中测试刺激期间测量棕色脂肪组织（BAT）中的温度升高，以确定用于植入的适当的神经电极放置。 方法可以包括确定具有最多BAT的患者的侧面，并且优先地在该右侧或左侧刺激。 BAT可能通过刺激支配BAT沉积物的交感神经系统来燃烧脂肪。

    Retrievable stent and method of use thereof
    6.
    发明申请
    Retrievable stent and method of use thereof 审中-公开
    可检索的支架及其使用方法

    公开(公告)号：US20050080480A1

    公开(公告)日：2005-04-14

    申请号：US10960195

    申请日：2004-10-06

    申请人： Stephen Bolea ,  Robert Rykhus ,  Sidney Hauschild ,  Johann Neisz ,  Mark Polyak ,  Bradford Staehle

    发明人： Stephen Bolea ,  Robert Rykhus ,  Sidney Hauschild ,  Johann Neisz ,  Mark Polyak ,  Bradford Staehle

    IPC分类号： A61F2/90 ,  A61F2/06

    CPC分类号： A61F2/90 ,  A61F2/848 ,  A61F2/95 ,  A61F2002/9511 ,  A61F2002/9528

    摘要： A removable stent system and method for extraction of a removable stent from a target site is disclosed. The removable stent includes a removable stent having a collapsible end and a collapsing element configured for coupling with a removal tool. The collapsing element can be configured as a lasso or can be movable between two positions when deployed at a target site in vivo. The removable stent overcomes disadvantages and limitations of previous types of stents as well as overcoming complications during or following stent deployment in vivo. The removable stent further includes features that increase its ease of use and reduce the maneuvering required of devices or tools used to remove the stent. This then decreases the amount of effort required by the physician, the procedure time, and the level of discomfort experienced by a patient during the procedure.

    摘要翻译： 公开了一种用于从目标部位提取可移除支架的可移除支架系统和方法。 可拆卸支架包括具有可折叠端部的可拆卸支架和被构造成与拆卸工具联接的塌缩元件。 折叠元件可以被配置为套索，或者当在体内部署在目标部位时可以在两个位置之间移动。 可移除的支架克服了先前支架类型的缺点和局限性，并克服了体内支架展开期间或之后的并发症。 可拆卸支架还包括增加其易用性并减少用于移除支架的装置或工具所需的操纵的特征。 这样就减少了医师所需的努力量，手术时间以及患者在手术过程中所遇到的不适程度。

    Esophageal activity modulated obesity therapy
    7.
    发明授权
    Esophageal activity modulated obesity therapy 有权
    食管活动调节肥胖症治疗

    公开(公告)号：US08321030B2

    公开(公告)日：2012-11-27

    申请号：US12763980

    申请日：2010-04-20

    申请人： Jeremy Maniak ,  Johann Neisz

    发明人： Jeremy Maniak ,  Johann Neisz

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36007 ,  A61N1/0551

    摘要： Methods and devices for delivering electrical stimulation to the sympathetic nervous system in response to the onset of eating. In some methods, swallowing is detected which then initiates a dose of stimulation which can vary in intensity, frequency, or both over the dose length. In some methods, the dose length is between about one quarter hour and one hour. The dose frequency may increase, hold steady, then decrease over the dose duration so as to mimic the response of the gut stretch and nutrient receptors to receiving food. The dose can drive biomarkers indicative of eating, for example glucagon, glucose, FFA or glycerol to at least about half of their normal post eating levels and then stop so as to retain stimulation effectiveness for subsequent doses and to prolong battery life.

    摘要翻译： 用于向交感神经系统递送电刺激以响应于进食的方法和装置。 在一些方法中，检测吞咽，然后开始剂量的刺激，其可以在剂量长度上强度，频率或两者都变化。 在一些方法中，剂量长度在约四分之一小时至一小时之间。 剂量频率可能增加，保持稳定，然后在剂量持续时间内减少，以模拟肠道拉伸和营养受体对接受食物的反应。 该剂量可以将指示进食的生物标志物（例如胰高血糖素，葡萄糖，FFA或甘油）驱动至其正常饮食水平的至少约一半，然后停止，以保持后续剂量的刺激效果并延长电池寿命。

    ESOPHAGEAL ACTIVITY MODULATED OBESITY THERAPY
    8.
    发明申请
    ESOPHAGEAL ACTIVITY MODULATED OBESITY THERAPY 有权
    食疗活性调节性肥胖治疗

    公开(公告)号：US20100268306A1

    公开(公告)日：2010-10-21

    申请号：US12763980

    申请日：2010-04-20

    申请人： Jeremy Maniak ,  Johann Neisz

    发明人： Jeremy Maniak ,  Johann Neisz

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36007 ,  A61N1/0551

    摘要： Methods and devices for delivering electrical stimulation to the sympathetic nervous system in response to the onset of eating. In some methods, swallowing is detected which then initiates a dose of stimulation which can vary in intensity, frequency, or both over the dose length. In some methods, the dose length is between about one quarter hour and one hour. The dose frequency may increase, hold steady, then decrease over the dose duration so as to mimic the response of the gut stretch and nutrient receptors to receiving food. The dose can drive biomarkers indicative of eating, for example glucagon, glucose, FFA or glycerol to at least about half of their normal post eating levels and then stop so as to retain stimulation effectiveness for subsequent doses and to prolong battery life.

    摘要翻译： 用于向交感神经系统递送电刺激以响应于进食的方法和装置。 在一些方法中，检测吞咽，然后开始剂量的刺激，其可以在剂量长度上强度，频率或两者都变化。 在一些方法中，剂量长度在约四分之一小时至一小时之间。 剂量频率可能增加，保持稳定，然后在剂量持续时间内减少，以模拟肠道拉伸和营养受体对接受食物的反应。 该剂量可以将指示进食的生物标志物（例如胰高血糖素，葡萄糖，FFA或甘油）驱动至其正常饮食水平的至少约一半，然后停止，以保持后续剂量的刺激效果并延长电池寿命。