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1.发明申请METHOD FOR DETERMINING AT LEAST ONE APPLICABLE PATH OF MOVEMENT FOR AN OBJECT IN TISSUE 有权用于确定用于组织中的对象的运动的至少一个适用路径的方法公开(公告)号：US20130287280A1
公开(公告)日：2013-10-31
申请号：US13979150
申请日：2012-01-13
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , A61B17/3403 , A61B34/10 , A61B90/11 , A61B90/36 , A61B2034/107 , G06F19/00 , G06F19/321 , G06T15/08 , G06T2207/10081 , G06T2207/10088 , G06T2207/10136 , G06T2207/30016 , G06T2207/30241 , G16H50/20 , G16H50/50
摘要： The invention relates to a method for determining at least one applicable path (32) for the movement of an object, especially of a surgical and/or diagnostical device, in human tissue (14) or animal tissue by means of a data set of intensity data obtained by a 3D imaging technique, the applicable path (32) of movement connecting a starting position (28) of the device with a defined target location (30). According to the invention the method comprises the steps: defining the target location (30) of a reference point of the device and choosing at least one possible starting position of the reference point of the device; —determining a candidate path of movement (18, 20, 22) between the corresponding possible starting position (24,26, 28) and the defined target location (30); and—evaluating the candidate path of movement (18, 20, 22) as being an applicable path (32) depending on information about local intensity extrema and/or intensity variation resulting from the intensity data along the candidate path of movement (18, 20, 22). The invention further relates to a corresponding computer-readable medium, a corresponding computer program product, and a corresponding computerized system.
摘要翻译： 本发明涉及一种用于通过强度数据集来确定用于在人体组织（14）或动物组织中移动物体（特别是手术和/或诊断装置）的至少一个适用路径（32）的方法 通过3D成像技术获得的数据，将设备的起始位置（28）与定义的目标位置（30）连接的适用的运动路径（32）。 根据本发明，该方法包括以下步骤：定义设备的参考点的目标位置（30）并且选择设备的参考点的至少一个可能的起始位置; - 确定相应的可能起始位置（24,26,28）和所确定的目标位置（30）之间的候选移动路径（18,20,22）; 并且根据关于由沿着候选移动路径（18,20）的强度数据产生的局部强度极值和/或强度变化的信息，将候选运动路径（18,20,22）评估为可应用路径（32） ，22）。 本发明还涉及相应的计算机可读介质，相应的计算机程序产品和相应的计算机化系统。
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2.发明授权Method for determining at least one applicable path of movement for an object in tissue 有权用于确定组织中的物体的至少一个运动路径的方法公开(公告)号：US09286671B2
公开(公告)日：2016-03-15
申请号：US13979150
申请日：2012-01-13
CPC分类号： G06T7/0012 , A61B17/3403 , A61B34/10 , A61B90/11 , A61B90/36 , A61B2034/107 , G06F19/00 , G06F19/321 , G06T15/08 , G06T2207/10081 , G06T2207/10088 , G06T2207/10136 , G06T2207/30016 , G06T2207/30241 , G16H50/20 , G16H50/50
摘要： A method for determining an applicable path of movement of an object in human or animal tissue is based on intensity data obtained by a 3D imaging technique. The applicable path of movement connects a starling position of the object with a defined target location. The method includes defining the target location of a reference point of the object and choosing at least one possible starting position of the reference point of the object. Further, the method includes determining a candidate path of movement between the corresponding possible starling position and the defined target location. Next, the candidate path of movement is evaluated for being an applicable path. The candidate path is evaluated based on information about local intensity extrema and/or intensity variation resulting from the intensity data along the candidate path of movement.
摘要翻译： 用于确定人体或动物组织中的物体的运动路径的方法是基于通过3D成像技术获得的强度数据。 适用的运动路径将物体的星空位置与定义的目标位置相连。 该方法包括定义对象的参考点的目标位置并选择对象的参考点的至少一个可能的起始位置。 此外，该方法包括确定在相应的可能椋鸟位置和所定义的目标位置之间的候选移动路径。 接下来，评估候选运动路径作为适用路径。 基于从候选移动路径的强度数据产生的局部强度极值和/或强度变化的信息来评估候选路径。
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公开(公告)号：US09421359B2
公开(公告)日：2016-08-23
申请号：US13120758
申请日：2009-10-07
申请人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Ke Wang , Hubert Cecile Francois Martens , Franciscus Paulus Maria Budzelaar , Dirk Willem Harberts , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
CPC分类号： A61N1/05 , A61N1/0529 , A61N1/0531 , A61N1/0551 , A61N1/056 , A61N1/086 , H05K9/002
摘要： The invention relates to a probe for an implantable electro-stimulation device. The probe (20) has a distal end (12) and a proximal end (13), and moreover comprises: one or more electrodes (11) a shield (21) of conducting material covering a major part of the probe, said shield extending from the vicinity of at least one of the one or more electrodes (11) towards the proximal end (13) or towards the distal end (12) of the probe (20); and a layer (22a, 22b) of insulating material covering part of the shield (21) in the vicinity of the at least one of the one or more electrodes. The shield protects wires (14), extending from electrodes to the proximal end of the probe, from undesired interference of external RF fields. The exposed part of the shield not covered by the layer of insulating material serves as a return electrode for the electrostimulation signal path.
摘要翻译： 本发明涉及可植入电刺激装置的探针。 探针（20）具有远端（12）和近端（13），并且还包括：一个或多个电极（11）覆盖探针的主要部分的导电材料的屏蔽件（21），所述屏蔽件延伸 从所述一个或多个电极（11）中的至少一个朝向所述近端（13）或所述探针（20）的远端（12）的附近; 以及覆盖所述一个或多个电极中的至少一个电极附近的所述屏蔽体（21）的一部分的绝缘材料层（22a，22b）。 屏蔽保护从电极延伸到探针近端的电线（14）免受外部RF场的不期望的干扰。 未被绝缘材料层覆盖的屏蔽件的暴露部分用作电刺激信号路径的返回电极。
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公开(公告)号：US09259592B2
公开(公告)日：2016-02-16
申请号：US13119038
申请日：2009-09-17
申请人： Jacobus Josephus Leijssen , Hubert Cecile Francois Martens , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
发明人： Jacobus Josephus Leijssen , Hubert Cecile Francois Martens , Michael Marcel Jose Decre , Jeroen Jacob Arnold Tol
CPC分类号： A61N1/3787 , A61N1/00 , A61N1/0529 , A61N1/0534 , A61N1/36082 , A61N1/37276
摘要： The invention relates to an electronic apparatus (100) comprising a charging module (20) for receiving external energy (RF1) and for transferring it to a rechargeable energy storage (10) in a “charging state”. Moreover, the apparatus comprises a processing module which can be operated in a working state that is enabled if the charging module (20) is in the charging state and the apparatus is in a standard operating mode. The processing module may for example be a communication module (30) that can communicate wirelessly in its working state. In the standard operating mode, communication with the apparatus (100) is thus only possible if the apparatus (100) is simultaneously charged. The communication module (30) can therefore be completely switched off during the residual time, thus reducing power consumption and avoiding erroneous communication or misuse.
摘要翻译： 本发明涉及一种电子设备（100），包括用于接收外部能量（RF1）的充电模块（20）并将其传送到“充电状态”的可再充电能量存储器（10）。 此外，该装置包括处理模块，其可以在充电模块（20）处于充电状态并且该装置处于标准操作模式的情况下工作的工作状态下工作。 处理模块可以例如是可以在其工作状态下以无线方式通信的通信模块（30）。 在标准操作模式下，如果设备（100）同时充电，则与设备（100）的通信是可能的。 因此，通信模块（30）可以在剩余时间内完全关闭，从而降低功耗并避免错误的通信或误用。
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公开(公告)号：US08297997B2
公开(公告)日：2012-10-30
申请号：US13126361
申请日：2009-11-09
IPC分类号： H01R13/28
CPC分类号： A61N1/3752 , H01R12/75 , H01R2107/00 , H01R2201/12
摘要： A connector (10, 30, 40) is provided for coupling an electronic circuit (11) of an electronic device to sensor and/or actuation elements (12) of the electronic device. The connector (10, 30, 40) comprises at least one connection surface (21) with i connection points (13), the i connection points (13) comprise j primary connection points (13) for coupling the electronic circuit (11) to j corresponding ones of the elements (12), and k redundant connection points (13) for redundantly coupling the electronic circuit (11) to at least one of the elements (12). The primary and the redundant connection points (13) for the at least one of the elements (12) are distributed over the connection surface (21).
摘要翻译： 提供连接器（10,30,40），用于将电子设备的电子电路（11）耦合到电子设备的传感器和/或致动元件（12）。 连接器（10,30,40）包括具有i个连接点（13）的至少一个连接表面（21），i个连接点（13）包括j个主要连接点（13），用于将电子电路（11）耦合到 j个对应的元件（12）和k个用于将电子电路（11）冗余地耦合到元件（12）中的至少一个的冗余连接点（13）。 元件（12）中的至少一个元件的主要和冗余连接点（13）分布在连接表面（21）上。
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公开(公告)号：US20120109599A1
公开(公告)日：2012-05-03
申请号：US13285136
申请日：2011-10-31
IPC分类号： G06F7/60
CPC分类号： A61N1/37247 , A61N1/00
摘要： A system for planning implantation of a neurostimulation probe is provided. The system comprises an input for receiving anatomical data comprising information regarding a position and an orientation of at least one fiber bundle in a target region, an input for receiving therapeutic information comprising information regarding a stimulation preferability of the at least one fiber bundle, an optimization module for based on the position, the orientation and the stimulation preferability of the at least one fiber bundle calculating at least one optimal position and at least one optimal orientation for implantation of the neurostimulation probe at which optimal position and orientation the probe is capable of generating an electric field gradient substantially parallel to at least one fiber bundle with a high stimulation preferability and/or substantially perpendicular to at least one fiber bundle with a low stimulation preferability and an output for providing the optimal position and orientation.
摘要翻译： 提供了一种用于规划神经刺激探针植入的系统。 该系统包括用于接收包括关于目标区域中的至少一个纤维束的位置和取向的信息的解剖数据的输入，用于接收包括关于至少一个纤维束的刺激优选性的信息的治疗信息的输入，优化 模块，用于基于所述至少一个纤维束的位置，方向和刺激优选性计算至少一个最佳位置和至少一个用于植入神经刺激探针的最佳取向，其中探针能够产生最佳位置和取向 基本平行于具有高刺激优选性和/或基本垂直于具有低刺激优选性的至少一个纤维束的至少一个纤维束的电场梯度和用于提供最佳位置和取向的输出。
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公开(公告)号：US20110213382A1
公开(公告)日：2011-09-01
申请号：US13126283
申请日：2009-11-03
申请人： Michel Marcel Jose Decre , Johannes Cornelius Antonius Muller , Michel Gerarous Pardoel , Hubert Cecile Francois Martens
发明人： Michel Marcel Jose Decre , Johannes Cornelius Antonius Muller , Michel Gerarous Pardoel , Hubert Cecile Francois Martens
IPC分类号： A61B19/00
CPC分类号： A61N1/0534 , A61B5/6864 , A61N1/0539
摘要： A device for cranial implantation, comprising a ferrule and a plate for placement in the ferrule is provided. Furthermore, a neurological implant system comprising a probe and a device for cranial implantation is provided.
摘要翻译： 提供了一种用于头部植入的装置，其包括套圈和用于放置在套圈中的板。 此外，提供了包括探针和用于头部植入的装置的神经植入物系统。
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公开(公告)号：US20100036468A1
公开(公告)日：2010-02-11
申请号：US12518158
申请日：2007-11-16
CPC分类号： A61N1/36139 , A61N1/05 , A61N1/0529 , A61N1/0534 , A61N1/3605 , A61N1/3606 , A61N1/36082 , A61N1/36185
摘要： The disclosure is directed to a deep brain stimulation (DBS) lead having a distal end for providing therapeutic electrical stimulation to tissue in a stimulation target area of a patient's brain, comprising an array of one or more stimulation elements and sensing elements located at the distal end of the lead; each of the one or more stimulation elements is capable of providing electrical stimulation to the brain tissue in the target area; and each of the one or more sensing elements is capable of detecting electrical signals produced by nerve cells within the brain; wherein after the first implantation of the lead into the brain along a trajectory that is pre-determined by non-surgical procedures, the array of stimulation and sensing elements is capable of facilitating the location of the target area and the determination for each of the stimulation elements of the required stimulation parameters needed to provide the therapeutic stimulation to the brain tissue in the stimulation target area, without requiring any additional implantations of the lead after the first implantation. A stimulation system including the DBS lead and a pulse generator is disclosed. Also disclosed is a method of providing therapeutic DBS to brain tissue using the lead.
摘要翻译： 本公开涉及具有远端的深部脑刺激（DBS）引线，其用于向患者的大脑的刺激目标区域中的组织提供治疗性电刺激，包括一个或多个刺激元件的阵列和位于远端的感测元件 领先的结束 所述一个或多个刺激元件中的每一个能够向目标区域中的脑组织提供电刺激; 并且所述一个或多个感测元件中的每一个能够检测由脑内的神经细胞产生的电信号; 其中在沿着通过非外科手术预先确定的轨迹将引线首次植入脑中之后，刺激和感测元件的阵列能够促进目标区域的位置和每个刺激的确定 为了在刺激目标区域中的脑组织提供治疗刺激所需的刺激参数的要素，而不需要在第一次植入之后再进行铅的注入。 公开了包括DBS引线和脉冲发生器的刺激系统。 还公开了使用铅向脑组织提供治疗性DBS的方法。
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9.发明授权Method for recording information on a multi layer record carrier, and record carrier for use by such method 有权用于在多层记录载体上记录信息的方法，以及通过这种方法使用的记录载体公开(公告)号：US07480225B2
公开(公告)日：2009-01-20
申请号：US10568474
申请日：2004-08-20
申请人： Pierre Hermanus Woerlee , Hubert Cecile Francois Martens , Wilhelmus Robert Koppers , Robert Alberta Arnoldus Ponsen
发明人： Pierre Hermanus Woerlee , Hubert Cecile Francois Martens , Wilhelmus Robert Koppers , Robert Alberta Arnoldus Ponsen
IPC分类号： G11B7/00
CPC分类号： G11B7/00736 , G11B20/1217 , G11B27/329 , G11B2007/0013 , G11B2020/1227
摘要： This invention relates to a method for recording information on a multi layer record carrier. The information is recorded on the record carrier according to special filling patterns, such that the record carrier is compatible with the DVD-ROM standard while the time required for closing a session and/or finalizing the disc is reduced. The information is substantially evenly distributed over the layers in blocks of a predefined amount of storage space. The size of these blocks may be flexible and set by the method or read from the record carrier.
摘要翻译： 本发明涉及一种在多层记录载体上记录信息的方法。 信息根据特殊的填充模式被记录在记录载体上，使得记录载体与DVD-ROM标准兼容，同时减少了关闭会话和/或完成光盘所需的时间。 信息基本均匀地分布在预定量的存储空间的块中的层上。 这些块的大小可以是灵活的，通过该方法设置或从记录载体读取。
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公开(公告)号：US20080259759A1
公开(公告)日：2008-10-23
申请号：US10597565
申请日：2005-01-28
CPC分类号： G11B7/24085 , G11B7/004 , G11B7/0079 , G11B7/14 , G11B7/24038
摘要： A record carrier has information represented by high density read-only marks in a track. The read-only marks (74,75) are optically readable according to a predefined high-density data format such as CD or DVD via a beam of radiation by first variations of the radiation. The record carrier has a recordable layer (70) for writing recorded marks (72,73) in a recording area of the record carrier, which recording area extends over the track (9) carrying the read-only marks. The recordable layer (70) is arranged to generate second variations of the radiation by a difference between an unrecorded state and a recorded state. A recording device writes recorded marks on top of the read-only marks. A read device recovers the first and second variations, and detects the read-only marks and the recorded marks from a same part of the track.
摘要翻译： 记录载体具有由轨道中的高密度只读标记表示的信息。 根据预定的高密度数据格式（例如CD或DVD），通过辐射的第一变化经由辐射束，只读标记（74,75）是光学可读的。 记录载体具有用于在记录载体的记录区域中写入记录标记（72,73）的记录层（70），该记录区域在承载只读标记的轨道（9）上延伸。 可记录层（70）被布置成通过未记录状态和记录状态之间的差异来产生辐射的第二变化。 记录装置将记录标记写在只读标记之上。 读取装置恢复第一和第二变化，并且从轨道的相同部分检测只读标记和记录标记。
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