公开(公告)号：US20070079231A1

公开(公告)日：2007-04-05

申请号：US11243494

申请日：2005-10-03

申请人： Ahyh ,  Ken Kerr ,  George Smith ,  Richard Hanson ,  Gregg Janes ,  Dane Parker

发明人： Ahyh ,  Ken Kerr ,  George Smith ,  Richard Hanson ,  Gregg Janes ,  Dane Parker

IPC分类号： G06F17/00 ,  G06F17/30

CPC分类号： G06F8/71 ,  G06F8/36

摘要： A document construction and management system is described. In one embodiment, documents are assembled by combining one or more modules. In one embodiment, the modules are combined according to one or more construction rules. The modules can be provided to a number of subscribers, each subscriber having one or more users. Access to each of the modules can be controlled on a subscriber basis and/or on a user basis based on different users or user classes. When new modules or new versions of an existing module are added to the database of available modules, access to the new module or version can be restricted until the new modules or versions have been reviewed and accepted. During the review period, the previous version of the module is made available to users for construction of documents. In one embodiment, one or more access rules are used to control which modules are available to which users. In one embodiment, search rules are provided to facilitate searching for a desired module.

摘要翻译： 描述文件构建和管理系统。 在一个实施例中，通过组合一个或多个模块来组装文档。 在一个实施例中，根据一个或多个构造规则组合模块。 模块可以被提供给多个用户，每个用户具有一个或多个用户。 可以基于用户和/或基于不同用户或用户类别的用户来控制对每个模块的访问。 当现有模块的新模块或新版本添加到可用模块的数据库时，可以限制对新模块或版本的访问，直到新模块或版本已被审查和接受为止。 在审查期间，模块的先前版本可供用户构建文档。 在一个实施例中，使用一个或多个访问规则来控制哪些模块可用于哪些用户。 在一个实施例中，提供搜索规则以便于搜索期望的模块。

公开(公告)号：US20060141150A1

公开(公告)日：2006-06-29

申请号：US11023868

申请日：2004-12-27

申请人： Lei Zheng ,  John Lean ,  Eric Castner ,  Thierry Florent Materne ,  Dane Parker ,  Frank Feher

发明人： Lei Zheng ,  John Lean ,  Eric Castner ,  Thierry Florent Materne ,  Dane Parker ,  Frank Feher

IPC分类号： B01J13/02

CPC分类号： C08F279/02 ,  C08F257/02 ,  C08F291/00 ,  C08F2/38

摘要： The present invention discloses a process for producing a core-shell polymer that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, optional one crosslinking monomer (b) a conjugate acid of a surfactant with a pKa of less than 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier to produce a polymerization medium, and (4) initiating free radical polymerization within the polymerization medium to produce a core polymer, wherein the core contains a free radical control agents, (5) adding a second monomer to the polymerization medium containing the core polymer, and (6) allowing polymerization to proceed in the presence of the free radical control agent to produce the core-shell polymer.

摘要翻译： 本发明公开了一种制备核 - 壳聚合物的方法，其包括：（1）制备单体溶液，该单体溶液由（a）至少一种单体，任选的一种交联单体（b）表面活性剂的共轭酸与 pKa小于14，（c）受控自由基聚合剂; （2）制备由（a）水和（b）弱酸的共轭碱组成的水性介质，其中碱的pKb小于14; 和（3）在导致乳化剂原位形成以产生聚合介质的条件下将单体溶液与水性介质混合，和（4）在聚合介质内引发自由基聚合以制备芯聚合物，其中 核心包含自由基控制剂，（5）在含有核聚合物的聚合介质中加入第二单体，和（6）在自由基控制剂的存在下使聚合进行以制备核 - 壳聚合物。

公开(公告)号：US20050282957A1

公开(公告)日：2005-12-22

申请号：US11186305

申请日：2005-07-21

申请人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

发明人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

IPC分类号： C08F2/22 ,  C08F2/24 ,  C08F2/38 ,  C08F293/00 ,  C08F2/00

CPC分类号： C08F297/048 ,  C08F2/22 ,  C08F2/38 ,  C08F12/08 ,  C08F293/00 ,  C08F293/005 ,  C08F2438/00 ,  C08F2438/01 ,  C08F2438/02 ,  C08F2438/03 ,  C08G61/08 ,  C08G2261/418 ,  C08L53/00 ,  C08L53/02 ,  C08L2666/02

摘要： The present invention discloses an emulsion polymerization process that comprises: (1) preparing an aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; and (2) initiating polymerization of said monomer within the aqueous polymerization medium. The subject invention more specifically reveals an emulsion polymerization process that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, (b) a conjugate acid of a surfactant with a pKa of less than 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier, and (4) initiating free radical polymerization.

摘要翻译： 本发明公开了一种乳液聚合方法，其包括：（1）制备由（a）至少一种单体，（b）聚合控制剂和乳化剂组成的水性聚合介质，其中， 位于水性聚合介质中; 和（2）在水性聚合介质中引发所述单体的聚合。 本发明更具体地揭示了一种乳液聚合方法，其包括：（1）制备单体溶液，其包含（a）至少一种单体，（b）表面活性剂的共轭酸与pK < SUB>小于14，和（c）受控自由基聚合剂; （2）制备由（a）水和（b）弱酸的共轭碱组成的水性介质，其中所述碱的pK 小于14; 和（3）在导致乳化剂原位形成的条件下将单体溶液与水性介质混合，和（4）引发自由基聚合。

公开(公告)号：US20080033197A1

公开(公告)日：2008-02-07

申请号：US11895331

申请日：2007-08-24

申请人： Dane Parker

发明人： Dane Parker

IPC分类号： C07F9/6584

CPC分类号： C08F2/38 ,  C07F9/6584

摘要： This invention discloses a process for producing a polymer by controlled polymerization which comprises polymerizing at least one monomer in the presence of a free radical control agent of the structural formula: (Z)-(R1)n, wherein n represents an integer from 1 to about 6; wherein Z represents an aromatic or aliphatic moiety containing from 1 to about 20 carbon atoms; wherein R1 represents a moiety of the structural formula: wherein R2 represents a moiety selected from the group consisting of alkyl groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, and alkaryl groups; wherein the alky groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, and alkaryl groups can be substituted, unsubstituted, linear, branched or cyclic; and wherein Ar represents a p-alkoxyphenyl group having an alkoxy moiety that contains from 1 to 8 carbon atoms.

摘要翻译： 本发明公开了一种通过控制聚合制备聚合物的方法，该方法包括在下列结构式的自由基控制剂存在下聚合至少一种单体：（Z） - （R 1） 其中n表示1至约6的整数; 其中Z表示含有1至约20个碳原子的芳族或脂族部分; 其中R 1表示结构式的部分：其中R 2表示选自烷基，烯基，炔基，芳基，杂芳基的部分 基团和烷芳基; 其中烷基，烯基，炔基，芳基，杂芳基和烷芳基可以是取代的，未取代的，直链的，支链的或环状的; 并且其中Ar表示具有含有1至8个碳原子的烷氧基部分的对 - 烷氧基苯基。

公开(公告)号：US20060241258A1

公开(公告)日：2006-10-26

申请号：US11454742

申请日：2006-06-16

申请人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

发明人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

IPC分类号： C08F4/00

CPC分类号： C08F297/048 ,  C08F2/22 ,  C08F2/38 ,  C08F12/08 ,  C08F293/00 ,  C08F293/005 ,  C08F2438/00 ,  C08F2438/01 ,  C08F2438/02 ,  C08F2438/03 ,  C08G61/08 ,  C08G2261/418 ,  C08L53/00 ,  C08L53/02 ,  C08L2666/02

摘要： The present invention discloses an emulsion polymerization process that comprises: (1) preparing an aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; and (2) initiating polymerization of said monomer within the aqueous polymerization medium. The subject invention more specifically reveals an emulsion polymerization process that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, (b) a conjugate acid of a surfactant with a pKa of less than 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier, and (4) initiating free radical polymerization.

摘要翻译： 本发明公开了一种乳液聚合方法，其包括：（1）制备由（a）至少一种单体，（b）聚合控制剂和乳化剂组成的水性聚合介质，其中， 位于水性聚合介质中; 和（2）在水性聚合介质中引发所述单体的聚合。 本发明更具体地揭示了一种乳液聚合方法，其包括：（1）制备单体溶液，其包含（a）至少一种单体，（b）表面活性剂的共轭酸与pK < SUB>小于14，和（c）受控自由基聚合剂; （2）制备由（a）水和（b）弱酸的共轭碱组成的水性介质，其中所述碱的pK 小于14; 和（3）在导致乳化剂原位形成的条件下将单体溶液与水性介质混合，和（4）引发自由基聚合。

公开(公告)号：US20080097057A1

公开(公告)日：2008-04-24

申请号：US11975313

申请日：2007-10-18

申请人： Dane Parker

发明人： Dane Parker

IPC分类号： C08F2/00

CPC分类号： C08F2/38 ,  C07F9/6584

摘要： This invention discloses a process for producing a polymer by controlled polymerization which comprises polymerizing at least one monomer in the presence of a free radical control agent of the structural formula: (Z)-(R1)n, wherein n represents an integer from 1 to about 6; wherein Z represents an aromatic or aliphatic moiety containing from 1 to about 20 carbon atoms; wherein R1 represents a moiety of the structural formula: wherein R2 represents a moiety selected from the group consisting of alkyl groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, and alkaryl groups; wherein the alky groups, alkenyl groups, alkynyl groups, aryl groups, heteroaryl groups, and alkaryl groups can be substituted, unsubstituted, linear, branched or cyclic; and wherein Ar represents a p-alkoxyphenyl group having an alkoxy moiety that contains from 1 to 8 carbon atoms.

公开(公告)号：US20080090962A1

公开(公告)日：2008-04-17

申请号：US11973411

申请日：2007-10-09

申请人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

发明人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

IPC分类号： C08F8/04

CPC分类号： C08F4/40 ,  C08F2/38 ,  C08F2/40 ,  C08F8/04 ,  C08F8/08 ,  C08F293/005

摘要： The present invention discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; (2) initiating polymerization of said monomer within the aqueous polymerization medium to produce a latex of an unsaturated polymer; (3) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer. The present invention further discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, (b) a conjugate acid of a surfactant with a pKa of less than about 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than about 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier; (4) initiating free radical polymerization to produce a latex of an unsaturated polymer; and (5) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer.

摘要翻译： 本发明公开了一种合成氢化聚合物的方法，该方法包括：（1）制备水性聚合介质，其由（a）至少一种单体，（b）聚合控制剂和乳化剂组成，其中乳化剂为 在水性聚合介质中原位制备; （2）在水性聚合介质中引发所述单体的聚合以产生不饱和聚合物的胶乳; （3）用（a）选自氧，空气和氢过氧化物的氧化剂处理不饱和聚合物的胶乳; （b）选自肼和肼的水合物的还原剂; 和（c）金属离子活化剂以产生氢化聚合物。 本发明还公开了一种合成氢化聚合物的方法，其包括：（1）制备单体溶液，该单体溶液包含（a）至少一种单体，（b）表面活性剂的共轭酸与pK 小于约14，和（c）受控自由基聚合剂; （2）制备由（a）水和（b）弱酸的共轭碱组成的水性介质，其中碱的pK 小于约14; 和（3）在导致乳化剂原位形成的条件下将单体溶液与水性介质混合; （4）引发自由基聚合以产生不饱和聚合物的胶乳; 和（5）用（a）选自氧，空气和氢过氧化物的氧化剂处理不饱和聚合物的胶乳; （b）选自肼和肼的水合物的还原剂; 和（c）金属离子活化剂以产生氢化聚合物。

公开(公告)号：US20060004210A1

公开(公告)日：2006-01-05

申请号：US10882824

申请日：2004-07-01

申请人： Dane Parker

发明人： Dane Parker

IPC分类号： C07D339/06

CPC分类号： C07D339/06

摘要： This invention provides a low cost technique for synthesizing cyclic trithiocarbonates by a simple one step process from epoxides that can be conducted under atmospheric pressure. This synthesis can be depicted as follows: wherein R represents a moiety selected from the group consisting of alkyl groups and aryl groups, wherein R′ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, and wherein R″ represents a moiety selected from the group consisting of alkyl groups, aryl groups, and hydrogen atoms, wherein the R moiety and the R′ moiety can be bonded together to form a cyclic structure, with the proviso that R″ represents a hydrogen atom if R′ represents an alkyl group or an aryl group. In this process carbon disulfide and a thiocyanate salt, such as potassium thiocyanate, are reacted with the epoxide in an ionic liquid, such as 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim] PF6) in the presence of water to produce the cyclic trithiocarbonate.

摘要翻译： 本发明提供了一种用于通过可在大气压下进行的环氧化物的简单的一步法合成环状三硫代碳酸酯的低成本技术。 该合成可以描述如下：其中R表示选自烷基和芳基的部分，其中R'表示选自烷基，芳基和氢原子的部分，其中R “表示选自烷基，芳基和氢原子的部分，其中R部分和R'部分可以键合在一起形成环状结构，条件是R”表示氢 原子，如果R'表示烷基或芳基。 在该方法中，将二硫化碳和硫氰酸盐如硫氰酸钾与环氧化物在离子液体中反应，例如1-丁基-3-甲基咪唑六氟磷酸盐（[Bmim] PF 6））在 存在水以产生环状三硫代碳酸酯。

公开(公告)号：US20050256253A1

公开(公告)日：2005-11-17

申请号：US11120222

申请日：2005-05-02

申请人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

发明人： Dane Parker ,  Frank Feher ,  Viswanath Mahadevan

IPC分类号： C08F2/38 ,  C08F4/40 ,  C08F8/04 ,  C08F8/08 ,  C08L1/00

CPC分类号： C08F4/40 ,  C08F2/38 ,  C08F2/40 ,  C08F8/04 ,  C08F8/08 ,  C08F293/005

摘要： The present invention discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; (2) initiating polymerization of said monomer within the aqueous polymerization medium to produce a latex of an unsaturated polymer; (3) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer. The present invention further discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, (b) a conjugate acid of a surfactant with a pKa of less than about 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than about 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier; (4) initiating free radical polymerization to produce a latex of an unsaturated polymer; and (5) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer.

摘要翻译： 本发明公开了一种合成氢化聚合物的方法，该方法包括：（1）制备水性聚合介质，其由（a）至少一种单体，（b）聚合控制剂和乳化剂组成，其中乳化剂为 在水性聚合介质中原位制备; （2）在水性聚合介质中引发所述单体的聚合以产生不饱和聚合物的胶乳; （3）用（a）选自氧，空气和氢过氧化物的氧化剂处理不饱和聚合物的胶乳; （b）选自肼和肼的水合物的还原剂; 和（c）金属离子活化剂以产生氢化聚合物。 本发明还公开了一种合成氢化聚合物的方法，其包括：（1）制备单体溶液，该单体溶液包含（a）至少一种单体，（b）表面活性剂的共轭酸与pK 小于约14，和（c）受控自由基聚合剂; （2）制备由（a）水和（b）弱酸的共轭碱组成的水性介质，其中碱的pK 小于约14; 和（3）在导致乳化剂原位形成的条件下将单体溶液与水性介质混合; （4）引发自由基聚合以产生不饱和聚合物的胶乳; 和（5）用（a）选自氧，空气和氢过氧化物的氧化剂处理不饱和聚合物的胶乳; （b）选自肼和肼的水合物的还原剂; 和（c）金属离子活化剂以产生氢化聚合物。

公开(公告)号：US20100068214A1

公开(公告)日：2010-03-18

申请号：US12520395

申请日：2007-12-19

申请人： Julian Rood ,  Keith Al-Hasani ,  John Boyce ,  Dane Parker

发明人： Julian Rood ,  Keith Al-Hasani ,  John Boyce ,  Dane Parker

IPC分类号： A61K39/40 ,  C07K14/00 ,  C07K16/00 ,  C07H21/00 ,  A61K38/16 ,  A61K39/02 ,  A61K31/7052 ,  C12Q1/68 ,  C40B40/10 ,  C40B40/08 ,  C40B30/04 ,  G01N33/68 ,  G01N33/48 ,  A61P31/04

CPC分类号： G01N33/56911 ,  A61K39/00 ,  C07K14/195 ,  Y10T436/143333

摘要： This invention relates to a prophylactic and/or therapeutic treatment of footrot, and in particular to a vaccine effective in prophylactic and/or therapeutic treatment of footrot. Specific polypeptides of Dichelobacter nodosus have been identified as vaccine candidates. In some embodiments the polypeptide is expressed more strongly when the bacterium is grown in vivo or is expressed more strongly in the presence of ovine hoof powder. In other embodiments the polypeptide are reactive against sera recovered from animals repeatedly infected with D. nodosus.

摘要翻译： 本发明涉及脚部的预防和/或治疗性治疗，特别涉及一种有效预防和/或治疗脚部动物的疫苗。 已经鉴定了结肠杆菌的特异性多肽作为疫苗候选物。 在一些实施方案中，当细菌在体内生长或在绵羊蹄粉存在下更强烈地表达时，多肽表达得更强。 在其它实施方案中，多肽对从重复感染D.结节的动物回收的血清反应。