公开(公告)号：US20230079759A1

公开(公告)日：2023-03-16

申请号：US18056531

申请日：2022-11-17

Applicant: Ajinomoto Co., Inc.

Inventor： Takashi HASHIMOTO ,  Yuichi NAKAHARA ,  Akira IMAIZUMI ,  Ippei INOUE ,  Hiroshi UMISHIO ,  Megumi YAMADA

IPC: G01N29/44 ,  G01N29/036 ,  G01N29/02

Abstract: A compatibility prediction method includes predicting compatibility between a prediction target food and a prediction target drink using: a model for predicting the compatibility between the prediction target food and the prediction target drink, and measurements that are values related to predetermined information obtained when a measuring instrument measures aroma components of the prediction target food and the prediction target drink or calculations calculated based on the measurements.

公开(公告)号：US20230279063A1

公开(公告)日：2023-09-07

申请号：US18062906

申请日：2022-12-07

Applicant: Ajinomoto Co., Inc.

Inventor： Kei YAMADA ,  Ippei INOUE ,  Natsuki SHIKIDA ,  Kazutaka SHIMBO

IPC: C07K14/47 ,  A61K47/64

CPC classification number: C07K14/47 ,  A61K47/64

Abstract: Controlling the number of modifying groups introduced into a surface of ferritin affords a modified ferritin containing a human ferritin H chain, in which the human ferritin H chain contains a modifying group that is covalently bonded specifically to a cysteine residue at position 91 and/or position 103 according to a reference position of a natural human ferritin H chain.

公开(公告)号：US20140150855A1

公开(公告)日：2014-06-05

申请号：US14176543

申请日：2014-02-10

Applicant: AJINOMOTO CO., INC.

Inventor： Ippei INOUE ,  Ichiro Yamashita ,  Bin Zheng ,  Hisashi Yasueda ,  Yukiharu Uraoka ,  Yasuaki Ishikawa

IPC: H01G9/20 ,  H01L31/18

CPC classification number: H01L31/1884 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/16 ,  C01B32/174 ,  C01G9/02 ,  C01G23/047 ,  C07K14/195 ,  C07K2319/00 ,  C07K2319/20 ,  C07K2319/70 ,  H01G9/2031 ,  H01G9/204 ,  H01G9/2045 ,  H01L51/0049 ,  H01L51/0093 ,  H01L51/444 ,  H01M4/8605 ,  Y02E10/542 ,  Y02E10/549 ,  Y02P70/521

Abstract: A functional material having excellent photocatalytic activity, electric characteristics and the like is provided. A porous structure body 10 comprises a first target material 20 and an aggregate body 30 formed by aggregation of the first material. The aggregate body 30 adheres to the first target material and is located so as to surround the first target material. The aggregate body has a plurality of first pores 32 unevenly distributed near the first target material in the aggregate body and a plurality of second pores 34 scattered over the aggregate body.

Abstract translation: 提供了具有优异的光催化活性，电特性等的功能材料。 多孔结构体10包括第一靶材料20和通过第一材料的聚集形成的骨料体30。 聚集体30粘附到第一目标材料并且被定位成围绕第一靶材料。 骨料主体具有多个不均匀分布在聚集体中的第一目标材料附近的第一孔32和散布在聚集体上的多个第二孔34。

公开(公告)号：US20240018272A1

公开(公告)日：2024-01-18

申请号：US18460810

申请日：2023-09-05

Applicant: AJINOMOTO CO., INC.

Inventor： Yuichi NAKAHARA ,  Yuta ENDO ,  Ippei INOUE ,  Takahiro OKASORA ,  Junko YAMAZAKI HOSHIDA ,  Sachise KARAKAWA

IPC: C07K17/04 ,  C07K14/435

CPC classification number: C07K17/04 ,  C07K14/435

Abstract: the present invention provides a method for producing a protein having a supramolecular structure in which a bioactive substance is encapsulated, comprising: (I) bringing a subunit of a protein, which forms a supramolecular structure, a bioactive substance, and a solution for forming the protein having the supramolecular structure from the subunit into contact with one another in a flow micro mixer.

公开(公告)号：US20220401560A1

公开(公告)日：2022-12-22

申请号：US17685643

申请日：2022-03-03

Applicant: Ajinomoto Co., Inc.

Inventor： Ippei INOUE ,  Kenichiro ITO ,  Mayumi TOKUYAMA

IPC: A61K47/42

Abstract: Peptide-encapsulating ferritins including a peptide that is composed of 3 to 19 amino acid residues and satisfies the following requirement:
a) −10.2≤X≤5.9 and 445≤Y≤2,524
wherein X represents a charge of the peptide at pH 9, and I represents a chemical formula weight of the peptide are useful for transporting a peptide while avoiding destruction of cellular membrane, immunogenicity, and toxicity

公开(公告)号：US20240058473A1

公开(公告)日：2024-02-22

申请号：US18467134

申请日：2023-09-14

Applicant: Ajinomoto Co., Inc.

Inventor： Kei YAMADA ,  Yutaka MATSUDA ,  Ippei INOUE ,  Natsuki SHIKIDA ,  Kazutaka SHIMBO

IPC: A61K47/69 ,  A61K47/68

CPC classification number: A61K47/6949 ,  A61K47/6835 ,  A61K47/6889

Abstract: The present invention provides a highly controlled complex comprising an antibody and ferritin particles. More specifically, the present invention provides the inventions of a complex or salt thereof comprising (A) one IgG antibody and (B) two human ferritin particles comprising one or more human ferritin H chains linked thereto; and methods for producing the same.

公开(公告)号：US20210253651A1

公开(公告)日：2021-08-19

申请号：US17242379

申请日：2021-04-28

Applicant: Ajinomoto Co., Inc.

Inventor： Ippei INOUE ,  Yuichi NAKAHARA

IPC: C07K14/47 ,  A61K47/42

Abstract: An organic compound-encapsulating ferritin may be prepared by: (1) mixing an organic compound with ferritin in a buffer to obtain a mixture of the organic compound and ferritin; and (2) incubating the mixture in the buffer, wherein the buffer has a pH of 3 or more and less than 13, and the buffer has a pH of 3 or more and less than 7 when the organic compound has a pKa less than 7, and has a pH of 6 or more and less than 13 when the organic compound has a pKa of 7 or more.