-
公开(公告)号：US20100151574A1
公开(公告)日：2010-06-17
申请号：US12664343
申请日：2008-06-16
IPC分类号： C12N5/077
CPC分类号： C12N5/0667
摘要： Disclosed is a cell mass containing an adipose-tissue-derived multipotent progenitor cell. Also disclosed is a method for producing an adipose-tissue-derived multipotent progenitor cell from an adipose tissue, which comprises the steps of: (a) removing erythrocytes from an adipose-tissue-derived cell mass to produce a preadipose-tissue-derived multipotent progenitor cell mass; and (b) removing cells other than the adipose-tissue-derived multipotent progenitor cell from the preadipose-tissue-derived multipotent progenitor cell mass to produce the desired adipose-tissue-derived multipotent progenitor cell. Further disclosed is an adipose-tissue-derived multipotent progenitor cell produced by the method.
摘要翻译： 公开了含有脂肪组织衍生的多能祖细胞的细胞团。 还公开了从脂肪组织制备脂肪组织衍生的多能祖细胞的方法，其包括以下步骤：（a）从脂肪组织衍生的细胞块中除去红细胞，以产生前脂组织衍生的多能 祖细胞; 和（b）除去来自前脂肪组织衍生的多能祖细胞的脂肪组织衍生的多能祖细胞以外的细胞，以产生所需的脂肪组织衍生的多能祖细胞。 进一步公开的是通过该方法生产的脂肪组织衍生的多能祖细胞。
-
公开(公告)号：US09845458B2
公开(公告)日：2017-12-19
申请号：US12664343
申请日：2008-06-16
IPC分类号： C12N5/00 , C12N5/0775
CPC分类号： C12N5/0667
摘要： Disclosed is a cell mass containing an adipose-tissue-derived multipotent progenitor cell. Also disclosed is a method for producing an adipose-tissue-derived multipotent progenitor cell from an adipose tissue, which comprises the steps of: (a) removing erythrocytes from an adipose-tissue-derived cell mass to produce a preadipose-tissue-derived multipotent progenitor cell mass; and (b) removing cells other than the adipose-tissue-derived multipotent progenitor cell from the preadipose-tissue-derived multipotent progenitor cell mass to produce the desired adipose-tissue-derived multipotent progenitor cell. Further disclosed is an adipose-tissue-derived multipotent progenitor cell produced by the method.
-
3.发明申请COMPOSITION FOR REGENERATION OF PERIODONTAL HARD TISSUE AND METHOD FOR REGENERATION OF PERIODONTAL HARD TISSUE 审中-公开用于再生胸腔硬组织的组合物和再生胸腔硬组织的方法公开(公告)号：US20100068188A1
公开(公告)日：2010-03-18
申请号：US12311275
申请日：2007-09-20
CPC分类号： A61L27/3865 , A61K35/12 , A61L27/3834 , A61L27/3895 , A61L2430/12 , C12N5/0654 , C12N2500/38 , C12N2500/42 , C12N2501/30 , C12N2501/39 , C12N2506/1384
摘要： An object of the present invention is to provide technology of using a preadipocyte to restore comprehensively bone, cartilage and periodontal ligament, and cause a periodontal hard tissue to regenerate. By culturing a preadipocyte using a culture medium containing (i) at least one member selected from the group consisting of glycerophosphate and salts thereof, and (ii) at least one member selected from the group consisting of ascorbic acid, derivatives thereof and salts thereof and not containing an adrenal cortical hormone in such an amount that promotes differentiation of a preadipocyte into a periodontal hard tissue cell, differentiation of the cell into a periodontal hard tissue cell is induced efficiently. Furthermore, a scaffold is combined with the preadipocyte cultured with the above-mentioned culture medium to be transplanted into a periodontal tissue that requires regeneration.
摘要翻译： 本发明的目的是提供使用前脂肪细胞全面恢复骨，软骨和牙周韧带并使牙周硬组织再生的技术。 通过使用培养基培养前脂肪细胞，所述培养基含有（i）选自甘油磷酸盐及其盐的至少一种，和（ii）至少一种选自抗坏血酸，其衍生物和盐及其盐的成员，以及 不含有促进前脂肪细胞分化为牙周硬组织细胞的量的肾上腺皮质激素，有效诱导细胞向牙周硬组织细胞的分化。 此外，将支架与与上述培养基一起培养的前脂肪细胞组合以移植到需要再生的牙周组织中。
-
公开(公告)号：US09428733B2
公开(公告)日：2016-08-30
申请号：US13507249
申请日：2012-06-15
IPC分类号： C12N5/0775 , A61K35/12 , C12N5/071 , G01N33/50
CPC分类号： C12N5/0676 , A61K35/12 , C12N5/0653 , C12N5/0667 , C12N5/0678 , C12N2500/25 , C12N2500/32 , C12N2500/33 , C12N2500/38 , C12N2501/115 , C12N2501/335 , C12N2503/02 , C12N2506/1384 , C12N2533/52 , G01N33/507
摘要： A method of obtaining pancreatic endocrine cells from cells originating in an adipose tissue characterized by comprising culturing the adipose tissue-origin cells; the pancreatic endocrine cells that can be obtained thereby; a method of treating or preventing a disease caused by the hypofunction in pancreatic endocrine cells wherein the above-described pancreatic endocrine cells are used; a method of screening a substance capable of promoting or inhibiting the differentiation into pancreatic endocrine cells characterized by comprising adding a candidate substance to a medium in the course of culturing adipose tissue-origin cells to obtain the pancreatic endocrine cells; and so on.
-
5.发明申请Method for obtaining pancreatic endocrine cells from adipose tissue-origin cells 审中-公开从脂肪组织起源细胞获得胰腺内分泌细胞的方法公开(公告)号：US20130109092A1
公开(公告)日：2013-05-02
申请号：US13507249
申请日：2012-06-15
IPC分类号： C12N5/071
CPC分类号： C12N5/0676 , A61K35/12 , C12N5/0653 , C12N5/0667 , C12N5/0678 , C12N2500/25 , C12N2500/32 , C12N2500/33 , C12N2500/38 , C12N2501/115 , C12N2501/335 , C12N2503/02 , C12N2506/1384 , C12N2533/52 , G01N33/507
摘要： A method of obtaining pancreatic endocrine cells from cells originating in an adipose tissue characterized by comprising culturing the adipose tissue-origin cells; the pancreatic endocrine cells that can be obtained thereby; a method of treating or preventing a disease caused by the hypofunction in pancreatic endocrine cells wherein the above-described pancreatic endocrine cells are used; a method of screening a substance capable of promoting or inhibiting the differentiation into pancreatic endocrine cells characterized by comprising adding a candidate substance to a medium in the course of culturing adipose tissue-origin cells to obtain the pancreatic endocrine cells; and so on.
摘要翻译： 从源于脂肪组织的细胞获得胰内分泌细胞的方法，其特征在于包括培养所述脂肪组织起源细胞; 可以获得的胰腺内分泌细胞; 一种治疗或预防胰腺内分泌细胞中由功能低下引起的疾病的方法，其中使用上述胰内分泌细胞; 筛选能够促进或抑制分化成胰腺内分泌细胞的物质的方法，其特征在于包括在培养脂肪组织起源细胞的过程中向培养基中加入候选物质以获得胰内分泌细胞; 等等。
-
6.发明申请Method for Obtaining Pancreatic Endocrine Cells From Adipose Tissue-Origin Cells 审中-公开从脂肪组织起源细胞获得胰腺内分泌细胞的方法公开(公告)号：US20100322906A1
公开(公告)日：2010-12-23
申请号：US12083018
申请日：2006-08-14
CPC分类号： C12N5/0676 , A61K35/12 , C12N5/0653 , C12N5/0667 , C12N5/0678 , C12N2500/25 , C12N2500/32 , C12N2500/33 , C12N2500/38 , C12N2501/115 , C12N2501/335 , C12N2503/02 , C12N2506/1384 , C12N2533/52 , G01N33/507
摘要： A method of obtaining pancreatic endocrine cells from cells originating in an adipose tissue characterized by comprising culturing the adipose tissue-origin cells; the pancreatic endocrine cells that can be obtained thereby; a method of treating or preventing a disease caused by the hypofunction in pancreatic endocrine cells wherein the above-described pancreatic endocrine cells are used; a method of screening a substance capable of promoting or inhibiting the differentiation into pancreatic endocrine cells characterized by comprising adding a candidate substance to a medium in the course of culturing adipose tissue-origin cells to obtain the pancreatic endocrine cells; and so on.
摘要翻译： 从源于脂肪组织的细胞获得胰内分泌细胞的方法，其特征在于包括培养所述脂肪组织起源细胞; 可以获得的胰腺内分泌细胞; 一种治疗或预防胰腺内分泌细胞中由功能低下引起的疾病的方法，其中使用上述胰内分泌细胞; 筛选能够促进或抑制分化成胰腺内分泌细胞的物质的方法，其特征在于包括在培养脂肪组织起源细胞的过程中向培养基中加入候选物质以获得胰内分泌细胞; 等等。
-
7.发明申请METHOD FOR PRODUCTION OF HEPATIC-LOBULE-LIKE CELL CLUSTER FROM ADIPOSE-TISSUE-DERIVED CELL 审中-公开用于从ADIPOSE-TISSUE-DERIVED细胞中产生肝细胞样细胞簇的方法公开(公告)号：US20100183568A1
公开(公告)日：2010-07-22
申请号：US12664344
申请日：2008-06-16
申请人： Akifumi Matsuyama , Hiroshi Komoda , Yoshiki Sawa
发明人： Akifumi Matsuyama , Hiroshi Komoda , Yoshiki Sawa
IPC分类号： C12N5/071 , A61K35/00 , A61K35/407 , C12Q1/02 , C07K14/00
CPC分类号： C12N5/0667
摘要： Disclosed are: a method for producing a hepatic-lobule-like cell mass from an adipose-tissue-derived cell, which is characterized by culturing the adipose-tissue-derived cell; a hepatic-lobule-like cell mass produced by the method; a method for the screening of a substance capable of promoting or inhibiting the formation of a hepatic-lobule-like cell mass, which is characterized by culturing an adipose-tissue-derived cell to produce the hepatic-lobule-like cell mass, wherein a candidate substance is added to a culture medium; and a kit for use in the screening method.
摘要翻译： 公开了从脂肪组织来源的细胞产生肝小叶状细胞群的方法，其特征在于培养来自脂肪组织的细胞; 通过该方法产生的肝小叶状细胞块; 筛选能够促进或抑制肝小叶状细胞块形成的物质的方法，其特征在于培养脂肪组织来源的细胞以产生肝小叶状细胞块，其中a 将候选物质加入到培养基中; 以及用于筛选方法的试剂盒。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.023 秒)
