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    Living body light measuring device
    1.
    发明申请
    Living body light measuring device 有权
    活体光测量装置

    公开(公告)号：US20060241361A1

    公开(公告)日：2006-10-26

    申请号：US11348441

    申请日：2006-02-07

    申请人： Akiko Obata ,  Atsushi Maki ,  Kanehisa Morimoto

    发明人： Akiko Obata ,  Atsushi Maki ,  Kanehisa Morimoto

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14553 ,  A61B5/7264

    摘要： There is provided a living body light measuring device capable of monitoring a time curve of a blood substance concentration as time curves of parameters of a signal waveform and judging or analyzing characteristic traits of a subject relevant to the parameters of the signal waveform, wherein a signal processor extracts parameters such as a peak value and latency from a hemoglobin signal waveform measured before and after substance intake of a testee, and generates and displays a time curve graph having a parameter and time respectively as its ordinate and abscissa. Influence of an intake substance upon blood component concentrations and blood flow can be monitored by monitoring the time curves of parameters of the signal waveform. A category processor classifies measurement data into categories, analyzes time curves of a plurality of parameters every category, and displays a result on a result viewer.

    摘要翻译： 本发明提供一种生物体光测定装置，其能够将血液物质浓度的时间曲线作为信号波形的参数的时间曲线进行监视，并且判断或分析与信号波形的参数相关的被检体的特征特征，其中，信号 处理器从被测者的物质摄取之前和之后测量的血红蛋白信号波形提取诸如峰值和延迟的参数，并且生成并显示具有参数和时间的时间曲线图作为其纵坐标和横坐标。 摄入物质对血液成分浓度和血流量的影响可通过监测信号波形参数的时间曲线来监测。 类别处理器将测量数据分类，分析每个类别的多个参数的时间曲线，并在结果查看器上显示结果。

    Living body light measuring device
    2.
    发明授权
    Living body light measuring device 有权
    活体光测量装置

    公开(公告)号：US07349727B2

    公开(公告)日：2008-03-25

    申请号：US11348441

    申请日：2006-02-07

    申请人： Akiko Obata ,  Atsushi Maki ,  Kanehisa Morimoto

    发明人： Akiko Obata ,  Atsushi Maki ,  Kanehisa Morimoto

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14553 ,  A61B5/7264

    摘要： There is provided a living body light measuring device capable of monitoring a time curve of a blood substance concentration as time curves of parameters of a signal waveform and judging or analyzing characteristic traits of a subject relevant to the parameters of the signal waveform, wherein a signal processor extracts parameters such as a peak value and latency from a hemoglobin signal waveform measured before and after substance intake of a testee, and generates and displays a time curve graph having a parameter and time respectively as its ordinate and abscissa. Influence of an intake substance upon blood component concentrations and blood flow can be monitored by monitoring the time curves of parameters of the signal waveform. A category processor classifies measurement data into categories, analyzes time curves of a plurality of parameters every category, and displays a result on a result viewer.

    摘要翻译： 本发明提供一种生物体光测定装置，其能够将血液物质浓度的时间曲线作为信号波形的参数的时间曲线进行监视，并且判断或分析与信号波形的参数相关的被检体的特征特征，其中，信号 处理器从被测者的物质摄取之前和之后测量的血红蛋白信号波形提取诸如峰值和延迟的参数，并且生成并显示具有参数和时间的时间曲线图作为其纵坐标和横坐标。 摄入物质对血液成分浓度和血流量的影响可通过监测信号波形参数的时间曲线来监测。 类别处理器将测量数据分类，分析每个类别的多个参数的时间曲线，并在结果查看器上显示结果。

    Biological optical measurement instrument
    3.
    发明授权
    Biological optical measurement instrument 有权
    生物光学测量仪器

    公开(公告)号：US08521243B2

    公开(公告)日：2013-08-27

    申请号：US12014311

    申请日：2008-01-15

    申请人： Hiroki Sato ,  Akiko Obata ,  Atsushi Maki ,  Kazutaka Ozaki ,  Takaomi Yasuhara ,  Ichiro Moda

    发明人： Hiroki Sato ,  Akiko Obata ,  Atsushi Maki ,  Kazutaka Ozaki ,  Takaomi Yasuhara ,  Ichiro Moda

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/4011 ,  A61B5/04842 ,  A61B5/04847 ,  A61B5/14553 ,  A61B5/4017 ,  A61B5/486

    摘要： Appropriate measurement and analysis parameters are set according to cerebral function to be measured. To measure gustatory function, a time period of absence of cerebral activity to be measured is set so as not to contain a period of 60 seconds after start of stimulation, an activity period for analysis for an oxyhemoglobin concentration change signal is set so as to contain a period between an instant after a lapse of 16 seconds, and an instant after a lapse of 25 seconds, after the start of the stimulation, and an activity period for analysis for a deoxyhemoglobin concentration change signal is set so as to contain a period between an instant after a lapse of 28 seconds and an instant after a lapse of 37 seconds after the start of the stimulation. Moreover, a time interval between stimulations is set to 80 seconds or more.

    摘要翻译： 根据要测量的脑功能设定适当的测量和分析参数。 为了测定放气功能，设定要测定的脑活动不存在的时间段，以使刺激开始后不含有60秒的期间，设定氧合血红蛋白浓度变化信号的分析活动期，使其含有 在经过16秒之后的瞬间与经过25秒之后的瞬间之间的时间之间，以及用于分析脱氧血红蛋白浓度改变信号的活动期间，设定为包含： 经过28秒之后的瞬间，以及在刺激开始后经过了37秒的瞬间。 此外，刺激之间的时间间隔设定为80秒以上。

    Biological optical measurement system
    4.
    发明申请
    Biological optical measurement system 有权

    公开(公告)号：US20060100525A1

    公开(公告)日：2006-05-11

    申请号：US11205160

    申请日：2005-08-17

    申请人： Takusige Katura ,  Naoki Tanaka ,  Hiroki Sato ,  Akiko Obata ,  Atsushi Maki

    发明人： Takusige Katura ,  Naoki Tanaka ,  Hiroki Sato ,  Akiko Obata ,  Atsushi Maki

    IPC分类号： A61B6/00

    CPC分类号： A61B5/6814 ,  A61B5/0059 ,  A61B5/024 ,  A61B5/14553

    摘要： A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity signals, a result, it is difficult to reduce the Mayer wave noise signal using a bandpass filter or a bandcut filter. Light irradiating units and light detecting units for detecting the emitted light that has been passed through or reflected within the tissue are provided. A biological signal measuring unit measures at least one of the pulsation, breathing, blood pressure, and temperature. The relationship between an optical signal obtained by the light detecting unit and a biological signal using non-linear analysis; and a computation for separating the biological noise signal from the optical signal on the basis of the obtained relationship.

    Biological optical measurement system
    5.
    发明授权
    Biological optical measurement system 有权
    生物光学测量系统

    公开(公告)号：US07565192B2

    公开(公告)日：2009-07-21

    申请号：US11205160

    申请日：2005-08-17

    申请人： Takusige Katura ,  Naoki Tanaka ,  Hiroki Sato ,  Akiko Obata ,  Atsushi Maki

    发明人： Takusige Katura ,  Naoki Tanaka ,  Hiroki Sato ,  Akiko Obata ,  Atsushi Maki

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6814 ,  A61B5/0059 ,  A61B5/024 ,  A61B5/14553

    摘要： A typical task assigned for measuring a brain activity signal lasts from 10 to 30 seconds. The frequency band of the Mayer wave noise signal is very close to the frequency bands of brain activity signals, a result, it is difficult to reduce the Mayer wave noise signal using a bandpass filter or a bandcut filter. Light irradiating units and light detecting units for detecting the emitted light that has been passed through or reflected within the tissue are provided. A biological signal measuring unit measures at least one of the pulsation, breathing, blood pressure, and temperature. The relationship between an optical signal obtained by the light detecting unit and a biological signal using non-linear analysis; and a computation for separating the biological noise signal from the optical signal on the basis of the obtained relationship.

    摘要翻译： 分配给测量大脑活动信号的典型任务持续10到30秒。 梅耶尔波噪声信号的频带非常接近脑活动信号的频带，结果是难以使用带通滤波器或带通滤波器来减少梅耶波噪声信号。 提供了用于检测已经通过或反射在组织内的发射光的光照射单元和光检测单元。 生物信号测量单元测量脉动，呼吸，血压和温度中的至少一个。 由光检测单元获得的光信号与使用非线性分析的生物信号之间的关系; 以及基于所获得的关系从生物噪声信号与光信号分离的计算。

    BIOLOGICAL OPTICAL MEASUREMENT INSTRUMENT
    6.
    发明申请
    BIOLOGICAL OPTICAL MEASUREMENT INSTRUMENT 有权
    生物光学测量仪器

    公开(公告)号：US20080188729A1

    公开(公告)日：2008-08-07

    申请号：US12014311

    申请日：2008-01-15

    申请人： Hiroki Sato ,  Akiko Obata ,  Atsushi Maki ,  Kazutaka Ozaki ,  Takaomi Yasuhara ,  Ichiro Moda

    发明人： Hiroki Sato ,  Akiko Obata ,  Atsushi Maki ,  Kazutaka Ozaki ,  Takaomi Yasuhara ,  Ichiro Moda

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/4011 ,  A61B5/04842 ,  A61B5/04847 ,  A61B5/14553 ,  A61B5/4017 ,  A61B5/486

    摘要： Appropriate measurement and analysis parameters are set according to cerebral function to be measured. To measure gustatory function, a time period of absence of cerebral activity to be measured is set so as not to contain a period of 60 seconds after start of stimulation, an activity period for analysis for an oxyhemoglobin concentration change signal is set so as to contain a period between an instant after a lapse of 16 seconds, and an instant after a lapse of 25 seconds, after the start of the stimulation, and an activity period for analysis for a deoxyhemoglobin concentration change signal is set so as to contain a period between an instant after a lapse of 28 seconds and an instant after a lapse of 37 seconds after the start of the stimulation. Moreover, a time interval between stimulations is set to 80 seconds or more.

    摘要翻译： 根据要测量的脑功能设定适当的测量和分析参数。 为了测定放气功能，设定要测定的脑活动不存在的时间段，以使刺激开始后不含有60秒的期间，设定氧合血红蛋白浓度变化信号的分析活动期，使其含有 在经过16秒之后的瞬间与经过25秒之后的瞬间之间的时间之间，以及用于分析脱氧血红蛋白浓度改变信号的活动期间，设定为包含： 经过28秒之后的瞬间，以及在刺激开始后经过了37秒的瞬间。 此外，刺激之间的时间间隔设定为80秒以上。

    GUIDED BONE REGENERATION MEMBRANE AND MANUFACTURING METHOD THEREOF
    9.
    发明申请
    GUIDED BONE REGENERATION MEMBRANE AND MANUFACTURING METHOD THEREOF 审中-公开
    引导骨再生膜及其制造方法

    公开(公告)号：US20110060413A1

    公开(公告)日：2011-03-10

    申请号：US12876665

    申请日：2010-09-07

    申请人： Toshihiro KASUGA ,  Akiko Obata ,  Kie Fujikura

    发明人： Toshihiro KASUGA ,  Akiko Obata ,  Kie Fujikura

    IPC分类号： A61F2/28 ,  B29C47/04

    CPC分类号： A61F2/2846 ,  A61F2/2803 ,  A61F2/3094 ,  A61F2002/30008 ,  A61F2002/30062 ,  A61F2002/30971 ,  A61F2002/4495 ,  A61F2210/0004 ,  A61F2250/0017

    摘要： A guided bone regeneration membrane has a bilayer structure including a first nonwoven fabric layer and a second nonwoven fabric layer. The first nonwoven fabric layer includes a fibrous substance containing a biodegradable resin as a principal component and further containing a siloxane, and the second nonwoven fabric layer includes a fibrous substance containing a biodegradable resin as a principal component. The first and second nonwoven fabric layers are electrospun nonwoven fabric layers, and the fibrous substance constituting the second nonwoven fabric layer has an average diameter smaller than that of the fibrous substance constituting the first nonwoven fabric layer. Specifically, the fibrous substance constituting the second nonwoven fabric layer preferably has an average diameter of more than 0 μm and equal to or less than 5 μm.

    摘要翻译： 引导骨再生膜具有包括第一无纺布层和第二无纺布层的双层结构。 第一无纺布层包括含有生物降解性树脂作为主要成分并且还含有硅氧烷的纤维状物质，第二无纺布层包含含有生物降解性树脂作为主要成分的纤维状物质。 第一无纺布层和第二无纺布层是电纺无纺布层，构成第二无纺布层的纤维物质的平均直径小于构成第一无纺布层的纤维物质的平均直径。 具体地，构成第二无纺布层的纤维状物质的平均直径优选大于等于5μm且小于等于5μm。