公开(公告)号：US20070213669A1

公开(公告)日：2007-09-13

申请号：US11368540

申请日：2006-03-07

申请人： Alan Eskuri ,  Christopher Johnson ,  Chad Harris ,  Matthew Hawk ,  Grace Kim

发明人： Alan Eskuri ,  Christopher Johnson ,  Chad Harris ,  Matthew Hawk ,  Grace Kim

IPC分类号： A61M5/178

CPC分类号： A61M25/0054 ,  A61M25/0045 ,  A61M25/0069 ,  A61M25/0084 ,  A61M25/0138

摘要： A catheter is provided for the injection of therapeutic agents at a target site within a patient's body. The catheter includes a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also includes a second elongated shaft in the form of a needle slidingly disposed in the first elongated shaft, the needle having a distal end and a proximal and a lumen extending therebetween. The catheter may include a flexible sleeve, wherein the flexible sleeve compresses along the inside of a curve and elongates along the outside of a curve. The catheter may additionally or alternatively include an adjustable distal tissue contact surface, wherein the position of the distal tissue contact surface may be adjusted with respect to a stop surface for stopping the advancement of a needle. The catheter may additionally or alternatively include a fluid pressure contact monitor.

摘要翻译： 提供导管，用于在患者体内的靶位置处注射治疗剂。 导管包括第一细长轴，其具有远端和近端以及在其间延伸的内腔。 导管还包括滑动地设置在第一细长轴中的针形式的第二细长轴，所述针具有远端和近端以及在其间延伸的内腔。 导管可以包括柔性套管，其中柔性套筒沿着曲线的内部压缩并沿着曲线的外侧延伸。 导管可另外地或替代地包括可调节的远端组织接触表面，其中远端组织接触表面的位置可以相对于止动表面进行调整，以阻止针的前进。 导管可以附加地或可选地包括流体压力接触监视器。

公开(公告)号：US20130267934A1

公开(公告)日：2013-10-10

申请号：US13441116

申请日：2012-04-06

申请人： Alan Eskuri

发明人： Alan Eskuri

IPC分类号： A61M25/09 ,  B21F1/00

CPC分类号： A61M25/09 ,  A61M2025/09083 ,  A61M2025/09108 ,  A61M2025/09175

摘要： A guidewire comprising an elongate guide member dimensioned for insertion within a body vessel of a subject is disclosed. The guide member defines a longitudinal axis and has trailing and leading end segments. The leading end segment has a reduced cross-sectional dimension relative to a cross-sectional dimension of the trailing end segment. The leading end segment includes at least one finger thereon. A first transverse dimension of the finger is greater than a corresponding first transverse dimension of the leading end segment in contact therewith.

摘要翻译： 公开了一种导丝，其包括用于插入到受试者的体内容器内的细长引导构件。 引导构件限定纵向轴线并具有拖尾和前端段。 前端段相对于后端段的横截面尺寸具有减小的横截面尺寸。 前端段包括至少一根手指。 手指的第一横向尺寸大于与其接触的前端部分的对应的第一横向尺寸。

公开(公告)号：US09326774B2

公开(公告)日：2016-05-03

申请号：US13565859

申请日：2012-08-03

申请人： Alan Eskuri

发明人： Alan Eskuri

IPC分类号： A61F2/06 ,  A61B17/12

CPC分类号： A61B17/12022 ,  A61B2017/12063 ,  A61B2017/1209

摘要： An apparatus for implanting a medical device is provided that can be severed by electrolysis from a delivery member positioned in a patient. The apparatus can include an electrolytically detachable component that interconnects the medical device and the delivery member. The detachable component can have at least one corrodible first portion being adapted to serve as an anode in electrolytic corrosion. The at least one first portion can define a body having an outer surface and at least one surface structure extending inwardly from the outer surface into the body. The first portion can be electrolytically corrodible when in contact with a body fluid such that the medical device may be severed by electrolysis.

摘要翻译： 提供了用于植入医疗装置的装置，其可以通过从定位在患者体内的输送构件进行电解而被切断。 该装置可以包括将医疗装置和递送部件互连的可电解的部件。 可拆卸部件可以具有至少一个可腐蚀的第一部分，适于在电解腐蚀中用作阳极。 至少一个第一部分可以限定具有外表面的主体和从外表面向内延伸到主体中的至少一个表面结构。 当与体液接触时，第一部分可以被电解腐蚀，使得医疗装置可能被电解切断。

公开(公告)号：US07857826B2

公开(公告)日：2010-12-28

申请号：US11297492

申请日：2005-12-08

申请人： Alan Eskuri ,  James G. Hansen

发明人： Alan Eskuri ,  James G. Hansen

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0076

摘要： An embolic protection filter having a reduced profile for placement within a body lumen is disclosed. An embolic protection filter in accordance with the present invention includes a filter frame slidably and rotationally disposed along a guidewire, a plurality of retaining collars coupled to a proximal end of the filter frame, a plurality of expandable struts each having a proximal section adapted to slide within a corresponding retaining collar, and a filter mesh coupled to a distal section of the expandable struts for filtering embolic debris.

摘要翻译： 公开了一种用于放置在体腔中的具有减小的轮廓的栓塞保护过滤器。 根据本发明的栓塞保护过滤器包括沿着导丝线可滑动地和旋转地设置的过滤器框架，多个保持套环，其耦合到过滤器框架的近端，多个可膨胀支柱，每个具有适于滑动 在相应的保持环内，以及过滤网，其连接到可膨胀支柱的远端部分，用于过滤栓塞碎片。

公开(公告)号：US20070123913A1

公开(公告)日：2007-05-31

申请号：US11621921

申请日：2007-01-10

申请人： Mel Beulke ,  Thomas Broome ,  Robert Cassell ,  John Daniel ,  Alan Eskuri ,  James Hansen ,  Gary Kostur ,  Douglas Molland ,  Scott Smith ,  Jeffrey Vogel ,  Anthony Vrba

发明人： Mel Beulke ,  Thomas Broome ,  Robert Cassell ,  John Daniel ,  Alan Eskuri ,  James Hansen ,  Gary Kostur ,  Douglas Molland ,  Scott Smith ,  Jeffrey Vogel ,  Anthony Vrba

IPC分类号： A61B17/10

CPC分类号： A61F2/013 ,  A61B2017/22049 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/005 ,  A61F2230/0067

摘要： Anchoring mechanisms for releasably securing an intravascular device along an elongated member such as a guidewire or catheter. The anchoring mechanism may include an object that can be actuated between an unlocked position and a locked position. In the unlocked position, the anchoring mechanism is slidably and rotationally disposed about the elongated member. In the locked position, the anchoring mechanism is releasably secured to the elongated member, preventing movement thereon. A placement mechanism such as a tubular member can be utilized to actuate the anchoring mechanism between the unlocked and locked positions.

摘要翻译： 锚定机构，用于沿着诸如导丝或导管的细长构件可释放地固定血管内装置。 锚固机构可以包括能够在解锁位置和锁定位置之间被致动的物体。 在解锁位置，锚定机构围绕细长构件可滑动地和旋转地设置。 在锁定位置，锚定机构可释放地固定到细长构件上，防止其上移动。 可以使用诸如管状构件的放置机构来致动解锁位置和锁定位置之间的锚固机构。

公开(公告)号：US20060041264A1

公开(公告)日：2006-02-23

申请号：US11255706

申请日：2005-10-21

申请人： Alan Eskuri

发明人： Alan Eskuri

IPC分类号： A61B17/08

CPC分类号： A61F2/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61F2/013 ,  A61M2025/0058 ,  Y10S310/80

摘要： The present invention is directed to novel apparatus for use in medical procedures relating to tubular body fluid conduits. According to a first aspect of the invention, a filter apparatus is provided for delivery over a guidewire within a tubular body conduit, such as a blood vessel. The filter apparatus comprises: (a) a filter element transformable between a collapsed state and a deployed state, wherein the filter element is adapted to filter particulate matter from fluid within the tubular body conduit while in the deployed state; and (b) a locking member comprising one or more electroactive polymer actuators which switch the locking member between (i) a locking state wherein the locking member securely engages the guidewire and (ii) a release state wherein the locking member is movable along the length of the guidewire. According to a second aspect of the invention, a connector apparatus is provided for use in making an anastomotic connection between first and second tubular fluid conduits in a patient. The connector apparatus comprises: (a) a locking member, which further comprises one or more electroactive polymer actuators that switch the locking member between a locking state and a release state; and (b) a connector body that is configured to permit flow of bodily fluid between the first and second tubular fluid conduits. The connector body has a first portion configured for insertion into an axial end of the first tubular fluid conduit and a second portion configured for insertion through a sidewall of the second tubular fluid conduit. The second portion of the connector body is further configured to securely engage the locking member when the locking member is in the locking state.

摘要翻译： 本发明涉及用于与管状体液管道相关的医疗程序中的新型装置。 根据本发明的第一方面，提供一种过滤器装置，用于在诸如血管的管状体导管内的导丝上输送。 过滤装置包括：（a）可在折叠状态和展开状态之间转换的过滤元件，其中所述过滤元件适于在所述展开状态下从所述管状主体导管内的流体中过滤颗粒物质; 和（b）锁定构件，其包括一个或多个电活性聚合物致动器，所述电活性聚合物致动器在（i）锁定状态（其中锁定构件牢固地接合导丝）和（ii）释放状态之间切换锁定构件，其中锁定构件可沿着长度移动 的导丝。 根据本发明的第二方面，提供一种用于在患者体内在第一和第二管状流体导管之间进行吻合连接的连接器装置。 连接器装置包括：（a）锁定构件，其还包括一个或多个电活性聚合物致动器，其在锁定状态和释放状态之间切换锁定构件; 和（b）连接器主体，其构造成允许体液在第一和第二管状流体管道之间流动。 连接器主体具有构造成用于插入第一管状流体导管的轴向端部的第一部分和被配置用于插入通过第二管状流体导管的侧壁的第二部分。 连接器主体的第二部分进一步构造成当锁定构件处于锁定状态时牢固地接合锁定构件。

公开(公告)号：US20130226033A1

公开(公告)日：2013-08-29

申请号：US13407182

申请日：2012-02-28

申请人： Alan Eskuri

发明人： Alan Eskuri

IPC分类号： A61M25/09

CPC分类号： A61M25/09 ,  A61M2025/09083 ,  A61M2025/09091 ,  A61M2025/09133

摘要： A guidewire for use in a medical procedure includes an elongate guide member dimensioned for insertion within a body vessel of a subject. The guide member defines a longitudinal axis and has trailing and leading end segments. The leading end segment has a reduced cross-sectional dimension relative to a cross-sectional dimension of the trailing end segment. The leading end segment includes a first core element comprising a first material and a second core element comprising a second material different from the first material and being forward of the first core element. The first material of the first core element has greater rigidity than the rigidity of the second material of the second core element, to thereby facilitate advancement of, and application of torque to, the leading end segment while minimizing deformation.

摘要翻译： 用于医疗过程的导丝包括细长导向构件，其尺寸适于插入到受试者的体内容器内。 引导构件限定纵向轴线并具有拖尾和前端段。 前端段相对于后端段的横截面尺寸具有减小的横截面尺寸。 前端段包括第一芯元件，其包括第一材料和第二芯元件，第二芯元件包括与第一材料不同的第二材料并且位于第一芯元件的前面。 第一芯元件的第一材料具有比第二芯元件的第二材料的刚性更大的刚性，从而有助于使前端段的前进和转矩施加到最小化变形。

公开(公告)号：US08162974B2

公开(公告)日：2012-04-24

申请号：US11345832

申请日：2006-02-02

申请人： Alan Eskuri ,  Anthony C. Vrba

发明人： Alan Eskuri ,  Anthony C. Vrba

IPC分类号： A61B17/08 ,  A61D1/00

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00597 ,  A61B2017/00606 ,  A61B2017/00619

摘要： Methods, apparatus, and systems for occluding a defective occlusion. Methods, apparatus, and systems include the use of an occlusion device having occluder pads. The distance between the occluder pads can be adjusted so as to compress tissue between the occluder pads to anchor the occlusion device to the tissue and to block the defective occlusion.

摘要翻译： 用于阻塞缺陷闭塞的方法，装置和系统。 方法，装置和系统包括使用具有封堵器垫的闭塞装置。 可以调节封堵器垫之间的距离，以便压缩封堵器垫之间的组织，以将闭塞装置锚定到组织​​上并阻止缺陷闭塞。

公开(公告)号：US07320698B2

公开(公告)日：2008-01-22

申请号：US10842195

申请日：2004-05-10

申请人： Alan Eskuri

发明人： Alan Eskuri

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61F2002/016 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/006 ,  A61F2230/008 ,  A61F2230/0093

摘要： An intravascular filter device comprising a frame having an open configuration and a closed configuration, the frame comprising a plurality of elongate members each having a proximal end and a distal end, and a proximal region and a distal region and being fixedly connected at the proximal end to each other; and a filter having an open end and a closed end disposed on the frame; wherein the elongate members have a bend distal the proximal region and a helical curve over a substantial length of the distal region when the elongate members are in the open configuration.

摘要翻译： 一种血管内过滤器装置，包括具有打开构造和闭合构型的框架，所述框架包括多个细长构件，每个细长构件具有近端和远端，以及近端区域和远端区域，并且在近端固定连接 对彼此; 以及具有设置在所述框架上的开口端和封闭端的过滤器; 其中当所述细长构件处于打开构型时，所述细长构件具有远离所述近侧区域的远侧弯曲部以及远侧区域的相当长度上的螺旋形曲线。

公开(公告)号：US20070021775A1

公开(公告)日：2007-01-25

申请号：US11466758

申请日：2006-08-23

申请人： Anthony Vrba ,  Alan Eskuri

发明人： Anthony Vrba ,  Alan Eskuri

IPC分类号： A61M29/00

CPC分类号： A61M25/09 ,  A61M25/09025 ,  A61M2025/09175

摘要： An intravascular guidewire having an articulating distal section for improved maneuverability beyond a lesion or other protrusion within a body lumen. An elongated core wire having an actuatable stop disposed thereon is adapted to have a reduced profile in a first position, and an enlarged profile in a second position. The actuatable stop can be adapted to expand by any number of means, including a spring coil, a polymeric tube or a mesh sleeve. In one particular embodiment, the actuatable stop comprises a distal section of a tubular member having a plurality of circumferentially disposed openings adapted to permit a plurality of struts disposed therebetween to expand in an outward direction when compressed axially.

摘要翻译： 一种血管内导丝，其具有铰接式远端部分，用于提高超过体腔内病变或其它突出部分的机动性。 具有设置在其上的可致动止动件的细长芯线适于在第一位置具有减小的轮廓，并且在第二位置具有放大轮廓。 可致动止动件可以适于通过任何数量的装置来膨胀，包括弹簧圈，聚合物管或网眼套筒。 在一个具体实施例中，可致动止动件包括管状构件的远端部分，其具有多个周向设置的开口，适于允许沿轴向压缩时在其间设置的多个支柱沿向外的方向膨胀。