公开(公告)号：US20070123913A1

公开(公告)日：2007-05-31

申请号：US11621921

申请日：2007-01-10

申请人： Mel Beulke ,  Thomas Broome ,  Robert Cassell ,  John Daniel ,  Alan Eskuri ,  James Hansen ,  Gary Kostur ,  Douglas Molland ,  Scott Smith ,  Jeffrey Vogel ,  Anthony Vrba

发明人： Mel Beulke ,  Thomas Broome ,  Robert Cassell ,  John Daniel ,  Alan Eskuri ,  James Hansen ,  Gary Kostur ,  Douglas Molland ,  Scott Smith ,  Jeffrey Vogel ,  Anthony Vrba

IPC分类号： A61B17/10

CPC分类号： A61F2/013 ,  A61B2017/22049 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/005 ,  A61F2230/0067

摘要： Anchoring mechanisms for releasably securing an intravascular device along an elongated member such as a guidewire or catheter. The anchoring mechanism may include an object that can be actuated between an unlocked position and a locked position. In the unlocked position, the anchoring mechanism is slidably and rotationally disposed about the elongated member. In the locked position, the anchoring mechanism is releasably secured to the elongated member, preventing movement thereon. A placement mechanism such as a tubular member can be utilized to actuate the anchoring mechanism between the unlocked and locked positions.

摘要翻译： 锚定机构，用于沿着诸如导丝或导管的细长构件可释放地固定血管内装置。 锚固机构可以包括能够在解锁位置和锁定位置之间被致动的物体。 在解锁位置，锚定机构围绕细长构件可滑动地和旋转地设置。 在锁定位置，锚定机构可释放地固定到细长构件上，防止其上移动。 可以使用诸如管状构件的放置机构来致动解锁位置和锁定位置之间的锚固机构。

公开(公告)号：US20080051671A1

公开(公告)日：2008-02-28

申请号：US11929007

申请日：2007-10-30

申请人： Thomas Broome ,  Anthony Vrba ,  Narin Anderson ,  Justin Crank ,  James Hansen ,  Horng-Ban Lin ,  Mark Smith

发明人： Thomas Broome ,  Anthony Vrba ,  Narin Anderson ,  Justin Crank ,  James Hansen ,  Horng-Ban Lin ,  Mark Smith

IPC分类号： A61B5/026

CPC分类号： A61B5/02158 ,  A61B5/02156 ,  A61F2/013

摘要： Devices and methods for monitoring the flow of blood through an intravascular device are disclosed. An apparatus for monitoring blood flow in accordance with an exemplary embodiment of the present invention includes an intravascular device coupled to an elongated member, a first sensor adapted to measure fluidic pressure proximal the intravascular device, a second sensor adapted to measure fluidic pressure distal the intravascular device, and a control unit for comparing the signals received from the first and second sensors to determine the pressure drop across the intravascular device.

摘要翻译： 公开了通过血管内装置监测血流的装置和方法。 根据本发明的示例性实施例的用于监测血流的装置包括联接到细长构件的血管内装置，适于测量血管内装置近侧的流体压力的第一传感器，适于测量血管内远端的流体压力的第二传感器 装置和控制单元，用于比较从第一和第二传感器接收的信号，以确定穿过血管内装置的压降。

公开(公告)号：US20070088384A1

公开(公告)日：2007-04-19

申请号：US11610292

申请日：2006-12-13

申请人： Anthony Vrba ,  Mel Beulke

发明人： Anthony Vrba ,  Mel Beulke

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/008

摘要： A distal protection device comprising a filter cartridge having a frame and filter material and a proximal region having a ridge adapted for interface with a retrieval device, wherein the retrieval device includes a distally located expandable cuff. The distal protection device is able to be deployed remotely in a body vessel lumen optionally using a guidewire and sheath and later retrieved using the retrieval device. A method of retrieving a cartridge from a body vessel lumen, the method comprising the steps of providing a filter cartridge disposed within a body vessel lumen; providing a retrieval device; advancing the retrieval device distally in the body vessel lumen until at least a portion of the retrieval device is distal the proximal most portion of the filter cartridge; engaging the filter cartridge with the retrieval device such that at least a portion of the filter cartridge is prevented from moving distally beyond at least a distal portion of the retrieval device; and advancing the retrieval device and the filter cartridge proximally from the body lumen.

摘要翻译： 一种远端保护装置，其包括具有框架和过滤材料的过滤器滤芯以及具有适于与取回装置接合的脊的近端区域，其中所述检索装置包括位于远侧的可扩张的袖带。 远端保护装置能够远程部署在体内血管腔内，任选地使用导丝和护套，并且随后使用检索装置检索。 一种从身体血管腔取回药筒的方法，所述方法包括以下步骤：提供设置在体管腔内的滤芯; 提供检索装置; 将取回装置向远侧推进体管腔，直到至少一部分取出装置远离滤筒的最近部分; 使所述滤筒与所述取回装置接合，使得所述滤筒的至少一部分被阻止远离所述取出装置的至少远端部分移动; 并且使取出装置和滤筒从体腔向近侧推进。

公开(公告)号：US20070021775A1

公开(公告)日：2007-01-25

申请号：US11466758

申请日：2006-08-23

申请人： Anthony Vrba ,  Alan Eskuri

发明人： Anthony Vrba ,  Alan Eskuri

IPC分类号： A61M29/00

CPC分类号： A61M25/09 ,  A61M25/09025 ,  A61M2025/09175

摘要： An intravascular guidewire having an articulating distal section for improved maneuverability beyond a lesion or other protrusion within a body lumen. An elongated core wire having an actuatable stop disposed thereon is adapted to have a reduced profile in a first position, and an enlarged profile in a second position. The actuatable stop can be adapted to expand by any number of means, including a spring coil, a polymeric tube or a mesh sleeve. In one particular embodiment, the actuatable stop comprises a distal section of a tubular member having a plurality of circumferentially disposed openings adapted to permit a plurality of struts disposed therebetween to expand in an outward direction when compressed axially.

摘要翻译： 一种血管内导丝，其具有铰接式远端部分，用于提高超过体腔内病变或其它突出部分的机动性。 具有设置在其上的可致动止动件的细长芯线适于在第一位置具有减小的轮廓，并且在第二位置具有放大轮廓。 可致动止动件可以适于通过任何数量的装置来膨胀，包括弹簧圈，聚合物管或网眼套筒。 在一个具体实施例中，可致动止动件包括管状构件的远端部分，其具有多个周向设置的开口，适于允许沿轴向压缩时在其间设置的多个支柱沿向外的方向膨胀。

公开(公告)号：US20070179527A1

公开(公告)日：2007-08-02

申请号：US11345832

申请日：2006-02-02

申请人： Alan Eskuri ,  Anthony Vrba

发明人： Alan Eskuri ,  Anthony Vrba

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00597 ,  A61B2017/00606 ,  A61B2017/00619

摘要： Methods, apparatus, and systems for occluding a defective occlusion. Methods, apparatus, and systems include the use of an occlusion device having occluder pads. The distance between the occluder pads can be adjusted so as to compress tissue between the occluder pads to anchor the occlusion device to the tissue and to block the defective occlusion.

摘要翻译： 用于阻塞缺陷闭塞的方法，装置和系统。 方法，装置和系统包括使用具有封堵器垫的闭塞装置。 可以调节封堵器垫之间的距离，以便压缩封堵器垫之间的组织，以将闭塞装置锚定到组织​​上并阻止缺陷闭塞。

公开(公告)号：US20050159773A1

公开(公告)日：2005-07-21

申请号：US10762683

申请日：2004-01-20

申请人： Thomas Broome ,  Anthony Vrba

发明人： Thomas Broome ,  Anthony Vrba

IPC分类号： A61F2/01 ,  A61M29/00

CPC分类号： A61F2/013 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2230/0008

摘要： Devices and systems for retrieving an intravascular device within a body lumen are disclosed. The retrieval device may comprise an elongated tubular member having a relatively stiff proximal segment, an expandable distal segment, and an inner lumen disposed about a guidewire. The distal segment may include a braid configured to expand when axially compressed. A dilator tip operatively coupled to the elongated tubular member and guidewire may be used to track the retrieval device through the body.

摘要翻译： 公开了用于在体腔内检索血管内装置的装置和系统。 取回装置可以包括细长的管状构件，其具有相对刚性的近端段，可扩张的远端段和围绕导丝布置的内腔。 远侧段可以包括构造成在轴向压缩时膨胀的编织物。 可操作地连接到细长管状构件和导丝的扩张器尖端可用于通过身体跟踪取回装置。

公开(公告)号：US20060015135A1

公开(公告)日：2006-01-19

申请号：US11224417

申请日：2005-09-12

申请人： Anthony Vrba ,  Lance Monroe ,  Scott Smith ,  David Sogard

发明人： Anthony Vrba ,  Lance Monroe ,  Scott Smith ,  David Sogard

IPC分类号： A61M29/00

CPC分类号： A61F2/01 ,  A61F2/95 ,  A61F2/958 ,  A61F2/966 ,  A61F2002/011 ,  A61F2230/005 ,  A61M25/0119

摘要： A medical device delivery system, having a rolling retractable sheath covering a medical device mounting region on the system is disclosed. The rolling retractable sheath comprises an inner wall and an outer wall and may be formed of one or more materials, optionally porous. Optionally, a lubricant may be applied selectively to the interior and exterior walls of the stent.

公开(公告)号：US20110263921A1

公开(公告)日：2011-10-27

申请号：US12980972

申请日：2010-12-29

申请人： Anthony Vrba ,  Dave Sogard ,  Raed Rizq ,  Dominic Allocco ,  Michael Gerdts ,  Gordon Kocur ,  Steve Kangas

发明人： Anthony Vrba ,  Dave Sogard ,  Raed Rizq ,  Dominic Allocco ,  Michael Gerdts ,  Gordon Kocur ,  Steve Kangas

IPC分类号： A61M37/00 ,  A61M36/04 ,  A61M25/00 ,  A61M5/00

CPC分类号： A61B18/18 ,  A61B18/02 ,  A61B18/04 ,  A61B18/20 ,  A61B18/24 ,  A61B2018/00023 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/0212 ,  A61B2018/0281 ,  A61B2018/046 ,  A61B2018/1861 ,  A61N5/1002 ,  A61N7/022 ,  A61N2007/003

摘要： A renal denervation apparatus includes a treatment element dimensioned for deployment on or within a renal artery of a patient. The treatment element comprises a predefined pattern arranged to complete at least one revolution of the treatment element. The apparatus includes a treatment source. The treatment source and treatment element are configured to cooperatively facilitate communication of an agent from the treatment source to the pattern arrangement of the treatment element. The treatment element is configured to deliver denervation therapy using the agent via the pattern arrangement to one or more regions of the renal artery adjacent the pattern arrangement, such that at least one complete revolution of the renal artery is subjected to the denervation therapy.

摘要翻译： 肾去神经支配装置包括用于部署在患者的肾动脉上或内部的治疗元件。 治疗元件包括布置成完成治疗元件的至少一圈的预定图案。 该装置包括处理源。 处理源和处理元件被配置为协同地促进试剂从处理源到处理元件的图案布置的连通。 治疗元件被配置为使用所述药剂经由图案布置将去神经治疗递送到与所述图案布置相邻的所述肾动脉的一个或多个区域，使得对所述肾动脉的至少一个完整的转动进行去神经支配治疗。

公开(公告)号：US20110264116A1

公开(公告)日：2011-10-27

申请号：US12980948

申请日：2010-12-29

申请人： Gordon Kocur ,  Dave Sogard ,  Anthony Vrba ,  Roger Hastings

发明人： Gordon Kocur ,  Dave Sogard ,  Anthony Vrba ,  Roger Hastings

IPC分类号： A61B17/10 ,  A61F2/82 ,  A61M29/00

CPC分类号： A61B17/12 ,  A61B2017/00606 ,  A61B2017/00778 ,  A61B2017/00867 ,  A61F2/04 ,  A61F2/86 ,  A61F2220/0041 ,  A61F2220/0058

摘要： Devices, systems, and methods facilitate modification of renal sympathetic nerve activity using a force generating arrangement. A device for mechanically modifying renal sympathetic nerve activity includes a contact arrangement having a shape that generally conforms to a portion of a renal artery wall and is configured for placement at the renal artery wall portion. A compression arrangement is configured to cooperate with the contact arrangement to place the wall portion of the renal artery in compression sufficient to achieve a desired reduction in renal sympathetic nerve activity. The compression arrangement and the contact arrangement are preferably configured to cooperatively place the wall portion of the renal artery in compression sufficient to irreversibly terminate renal sympathetic nerve activity.

摘要翻译： 装置，系统和方法利用力产生装置促进肾交感神经活动的改变。 用于机械修饰肾交感神经活动的装置包括具有通常与肾动脉壁的一部分一致的形状的接触装置，并被配置为放置在肾动脉壁部分。 压缩装置被配置为与接触装置协作以将肾动脉的壁部分压缩到足以实现肾交感神经活动期望的减少。 压缩装置和接触装置优选构造成协同地将肾动脉的壁部分协调地置于足以不可逆地终止肾交感神经活动的压缩中。

公开(公告)号：US20070100374A1

公开(公告)日：2007-05-03

申请号：US11608619

申请日：2006-12-08

申请人： Anthony Vrba

发明人： Anthony Vrba

IPC分类号： A61M29/00 ,  A61B1/267

CPC分类号： A61F2/013 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/008 ,  A61M25/09 ,  A61M2025/09075 ,  A61M2025/09141 ,  A61M2025/0915 ,  A61M2025/09183

摘要： A guidewire having a proximal section, a distal section, and a transition section is disclosed. In one exemplary embodiment of the present invention, the proximal section may be formed of a relatively stiff, inelastic material, whereas the distal section may be formed of a relatively flexible, elastic material having super-elastic properties. A coupling member may be placed adjacent to the transition section to secure the proximal and distal sections together.

摘要翻译： 公开了一种具有近端部分，远侧部分和过渡部分的导丝。 在本发明的一个示例性实施例中，近端部分可以由相对刚性的非弹性材料形成，而远端部分可以由具有超弹性特性的相对柔性的弹性材料形成。 联接构件可以邻近过渡部分放置以将近端部分和远端部分固定在一起。