公开(公告)号：US20210267208A1

公开(公告)日：2021-09-02

申请号：US17315559

申请日：2021-05-10

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Valerie Beck ,  Elias Shaheen

IPC分类号： A01N55/00 ,  C23C26/00 ,  A01N33/08 ,  C09D5/14 ,  C09D179/02 ,  B05D1/04 ,  A01N25/02 ,  B05D1/02 ,  C09D183/08 ,  A01N59/16 ,  B05D7/00 ,  A61L2/00 ,  B05D7/14 ,  C08G77/26

摘要： An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR′)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X−; +—N(CH3)2(C14H29)X−; +—N(C10H21)2(CH3)X−; —Cl or —NH2; X−=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4−, or ClO4−; and R′=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR′)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

公开(公告)号：US20210195902A1

公开(公告)日：2021-07-01

申请号：US17200245

申请日：2021-03-12

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Valerie Beck ,  Elias Shaheen

IPC分类号： A01N55/00 ,  A01N59/16 ,  A61L2/00 ,  C09D5/14 ,  A01N25/02 ,  A01N33/08 ,  B05D1/02 ,  B05D7/14 ,  B05D7/00 ,  C09D179/02 ,  C23C26/00 ,  B05D1/04 ,  C08G77/26 ,  C09D183/08

摘要： An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR′)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X−; +—N(CH3)2(C14H29)X−; +—N(C10H21)2(CH3)X−; —Cl or —NH2; X−=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4−, or ClO4; and R′=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR′)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

公开(公告)号：US20200068897A1

公开(公告)日：2020-03-05

申请号：US16591785

申请日：2019-10-03

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman

IPC分类号： A01N55/00 ,  C08G77/26 ,  B05D1/04 ,  C23C26/00 ,  C09D179/02 ,  B05D7/00 ,  B05D7/14 ,  B05D1/02 ,  A01N33/08 ,  A01N25/02 ,  C09D5/14 ,  A61L2/00 ,  A01N59/16 ,  C09D183/08

摘要： Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

公开(公告)号：US10993441B2

公开(公告)日：2021-05-04

申请号：US16591785

申请日：2019-10-03

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman ,  Daniel Moros

IPC分类号： C08G77/26 ,  A01N55/00 ,  B05D1/04 ,  C23C26/00 ,  C09D179/02 ,  B05D7/00 ,  B05D7/14 ,  B05D1/02 ,  A01N33/08 ,  A01N25/02 ,  C09D5/14 ,  A61L2/00 ,  A01N59/16 ,  C09D183/08 ,  C09D183/00 ,  C08K3/22 ,  C09D183/06 ,  C07F7/08

摘要： Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

公开(公告)号：US11442032B2

公开(公告)日：2022-09-13

申请号：US17234330

申请日：2021-04-19

申请人： Allied Bioscience, Inc.

发明人： Parham Asgari ,  Jie Fang ,  Gavri Grossman ,  Maha El-Sayed

IPC分类号： G01N23/223 ,  G01B15/02

摘要： A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

公开(公告)号：US11033031B1

公开(公告)日：2021-06-15

申请号：US17200245

申请日：2021-03-12

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Valerie Beck ,  Elias Shaheen

IPC分类号： C09D183/08 ,  A01N55/00 ,  A01N59/16 ,  A61L2/00 ,  C09D5/14 ,  A01N25/02 ,  A01N33/08 ,  B05D1/02 ,  B05D7/14 ,  B05D7/00 ,  C09D179/02 ,  C23C26/00 ,  B05D1/04 ,  C08G77/26 ,  C08K3/22 ,  C09D183/00

摘要： An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR′)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X−; +—N(CH3)2(C14H29)X−; +—N(C10H21)2(CH3)X−; —Cl or —NH2; X−=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4−, or ClO4−; and R′=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR′)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.

公开(公告)号：US20200240935A1

公开(公告)日：2020-07-30

申请号：US16749343

申请日：2020-01-22

申请人： Allied Bioscience, Inc.

发明人： Parham Asgari ,  Jie Fang ,  Gavri Grossman ,  Maha El-Sayed

IPC分类号： G01N23/223 ,  G01B15/02

摘要： A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

公开(公告)号：US11369114B2

公开(公告)日：2022-06-28

申请号：US17177850

申请日：2021-02-17

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman ,  Daniel Moros

IPC分类号： C09D183/08 ,  A01N55/00 ,  B05D1/04 ,  C23C26/00 ,  C09D179/02 ,  B05D7/00 ,  B05D7/14 ,  B05D1/02 ,  A01N33/08 ,  A01N25/02 ,  C09D5/14 ,  A61L2/00 ,  A01N59/16 ,  C08G77/26 ,  C09D183/00 ,  C08K3/22 ,  C09D183/06 ,  C07F7/08

摘要： Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.

公开(公告)号：US20210239630A1

公开(公告)日：2021-08-05

申请号：US17234330

申请日：2021-04-19

申请人： Allied Bioscience, Inc.

发明人： Parham Asgari ,  Jie Fang ,  Gavri Grossman ,  Maha El-Sayed

IPC分类号： G01N23/223 ,  G01B15/02

摘要： A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.

公开(公告)号：US20210169081A1

公开(公告)日：2021-06-10

申请号：US17177850

申请日：2021-02-17

申请人： ALLIED BIOSCIENCE, INC.

发明人： Gavri Grossman ,  Jie Fang ,  Parham Asgari ,  Maha El-Sayed ,  Craig Grossman ,  Daniel Moros

IPC分类号： A01N55/00 ,  C09D183/08 ,  A01N59/16 ,  C09D5/14 ,  A01N33/08 ,  B05D7/14 ,  A61L2/00 ,  C09D179/02 ,  C23C26/00 ,  C08G77/26 ,  B05D1/04 ,  A01N25/02 ,  B05D1/02 ,  B05D7/00 ,  C09D183/00 ,  C07F7/08 ,  C09D183/06 ,  C08K3/22

摘要： Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.