摘要:
New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
摘要翻译:新的氟化衍生物可用作表面活性剂或用于药物或标记物的运输,或用于药物靶向的药物,以及含有衍生物的用于医疗,化妆品和兽医用途的制剂,具有下式:其中RF是氟化基团 X是直链或支链的亚烷基,R 1是H或CH 3,R 2是具有至少一个OH基团的基团,R 3是衍生自氨基酸或肽的基团,n = 50和0 = m = 200,其中0.2 = n / n + m 1。 这些衍生物可用作前药或在生物学和医学中配制药物,化妆品和兽医制剂,特别是用作氧气和其它气体的载体的造影剂,或作为治疗中使用的物质的载体,或作为载体 的标记。
摘要:
Fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
摘要翻译:用作医药,化妆品和兽医用途的用作表面活性剂或药物或标记物或药物靶向运输和含有衍生物的制剂的氟化衍生物,具有下式:其中RF是氟化基团, X是直链或支链的亚烷基,R1是H或CH3,R2是具有至少一个OH基团的基团,R3是衍生自氨基酸或肽的基团,1≤n≤50和0 < / = m = 200,其中0.2 = n / n + m 1。 这些衍生物可用作前药或在生物学和医学中配制药物,化妆品和兽医制剂,特别是用作氧气和其它气体的载体,造影剂的组合物,或作为治疗用物质的载体或载体 的标记。
摘要:
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
摘要:
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
摘要:
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
摘要:
New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: wherein RF is a fluorinated radical, X is a linear or branched alkylene, R1 is H or CH3, R2 is a radical having at least one OH group, R3 is a radical derived from an amino acid or a peptide, 1≦n≦50 and 0≦m≦200 with 0.2≦n/n+m≦1. These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
摘要翻译:用作医药,化妆品和兽医用途的用作表面活性剂或用于药物或标记物或药物靶向的药物和含有衍生物的制剂的新的氟化衍生物,其具有下式:其中RF是氟化基团,X是直链或 支链亚烷基,R 1是H或CH 3,R 2是具有至少一个OH基团的基团,R 3是衍生自氨基酸或肽的基团,1 <= n <= 50和0 <= m <= 200,其中0.2 <= n / n + m <= 1。这些衍生物可用作前药或在生物学和医学中配制药物,化妆品和兽医制剂,特别是用作造影剂的氧气和其他气体的载体的组合物,或 作为治疗中使用的物质的载体,或作为标记物的载体。
摘要:
New fluorinated derivatives useful as surfactants or in the transport of drug or markers, or in drug targeting, and preparations containing the derivatives, for medical, cosmetic and veterinary uses, having the formula: ##STR1## wherein R.sub.F is a fluorinated radical, X is a linear or branched alkylene, R.sup.1 is H or CH.sub.3, R.sup.2 is a radical having at least one OH group, R.sup.3 is a radical derived from an amino acid or a peptide, 1.ltoreq.n.ltoreq.50 and 0.ltoreq.m.ltoreq.200 with 0.2.ltoreq.n/n+m.ltoreq.1.These derivatives can be used as prodrugs or in formulating pharmaceutical, cosmetic and veterinary preparations, in biology and medicine, notably in compositions acting as carriers of oxygen and other gases, of contrast agents, or as carriers of substances used in therapy, or as carriers of markers.
摘要翻译:新的氟化衍生物可用作表面活性剂或用于药物或标记物的运输,或用于药物靶向的药物,以及含有衍生物的用于医疗,化妆品和兽医用途的制剂,具有下式:其中RF是氟化基团 X是直链或支链的亚烷基,R 1是H或CH 3,R 2是具有至少一个OH基团的基团,R 3是衍生自氨基酸或肽的基团,n = 50和0 = m = 200,其中0.2 = n / n + m 1。 这些衍生物可用作前药或在生物学和医学中配制药物,化妆品和兽医制剂,特别是用作氧气和其它气体的载体,造影剂的组合物,或作为治疗用物质的载体或载体 的标记。
摘要:
The invention provides a file management method and system for managing file retrieval and access. The method operates at the operating system level within a file system of a computer device and allows creating file move links upon detection of a file move request. The file move link associates the file source location with the file target location and is stored within a file move link table of the file system for subsequent file access request. File path to target location is automatically retrieved and file reached transparently for the user.
摘要:
The present invention is a system and method for generating a personal voice font including, monitoring voice segments automatically from phone conversations of a user by a voice learning processor to generate a personalized voice font and delivering the personalized voice font (PVF) to the a server.
摘要:
Novel ampiphilic fluorocarbon molecules applicable as vectors for active ingredients, active molecules comprising such a vector and the use thereof in the pharmaceutical field, particularly for the production of medicaments.